Chemical Formula: C31H50N7O18P3S
Chemical Formula C31H50N7O18P3S
Found 19 metabolite its formula value is C31H50N7O18P3S
3-Oxoheptanoyl-CoA
C31H50N7O18P3S (933.2145790000001)
3-Oxoheptanoyl-CoA is also known as (3S)-3-Isopropenyl-6-oxoenanthoyl-CoA. 3-Oxoheptanoyl-CoA is considered to be slightly soluble (in water) and acidic. 3-Oxoheptanoyl-CoA is a fatty ester lipid molecule
2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA
C31H50N7O18P3S (933.2145790000001)
(4E,6Z)-3-Hydroxydeca-4,6-dienoyl-CoA
C31H50N7O18P3S (933.2145790000001)
(4e,6z)-3-hydroxydeca-4,6-dienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (4E_6Z)-3-hydroxydeca-4_6-dienoic acid thioester of coenzyme A. (4e,6z)-3-hydroxydeca-4,6-dienoyl-coa is an acyl-CoA with 10 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (4e,6z)-3-hydroxydeca-4,6-dienoyl-coa is therefore classified as a medium chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (4e,6z)-3-hydroxydeca-4,6-dienoyl-coa, being a medium chain acyl-CoA is a substrate for medium chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (4E,6Z)-3-Hydroxydeca-4,6-dienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (4E,6Z)-3-Hydroxydeca-4,6-dienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (4E,6Z)-3-Hydroxydeca-4,6-dienoyl-CoA into (4E_6Z)-3-Hydroxydeca-4_6-dienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (4E_6Z)-3-Hydroxydeca-4_6-dienoylcarnitine is converted back to (4E,6Z)-3-Hydroxydeca-4,6-dienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (4E,6Z)-3-Hydroxydeca-4,6-dienoyl-CoA occurs in four steps. First, since (4E,6Z)-3-Hydroxydeca-4,6-dienoyl-CoA is a medium chain acyl-CoA it is the substrate for a medium chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (4E,6Z)-3-Hydroxydeca-4,6-dienoyl-CoA, creating a double bond between the alpha and beta carbons. FAD ...
(6Z,8E)-3-Hydroxydeca-6,8-dienoyl-CoA
C31H50N7O18P3S (933.2145790000001)
(6z,8e)-3-hydroxydeca-6,8-dienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (6Z_8E)-3-hydroxydeca-6_8-dienoic acid thioester of coenzyme A. (6z,8e)-3-hydroxydeca-6,8-dienoyl-coa is an acyl-CoA with 10 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (6z,8e)-3-hydroxydeca-6,8-dienoyl-coa is therefore classified as a medium chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (6z,8e)-3-hydroxydeca-6,8-dienoyl-coa, being a medium chain acyl-CoA is a substrate for medium chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (6Z,8E)-3-Hydroxydeca-6,8-dienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (6Z,8E)-3-Hydroxydeca-6,8-dienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (6Z,8E)-3-Hydroxydeca-6,8-dienoyl-CoA into (6Z_8E)-3-Hydroxydeca-6_8-dienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (6Z_8E)-3-Hydroxydeca-6_8-dienoylcarnitine is converted back to (6Z,8E)-3-Hydroxydeca-6,8-dienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (6Z,8E)-3-Hydroxydeca-6,8-dienoyl-CoA occurs in four steps. First, since (6Z,8E)-3-Hydroxydeca-6,8-dienoyl-CoA is a medium chain acyl-CoA it is the substrate for a medium chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (6Z,8E)-3-Hydroxydeca-6,8-dienoyl-CoA, creating a double bond between the alpha and beta carbons. FAD ...
(4E,7E)-3-Hydroxydeca-4,7-dienoyl-CoA
C31H50N7O18P3S (933.2145790000001)
(4e,7e)-3-hydroxydeca-4,7-dienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (4E_7E)-3-hydroxydeca-4_7-dienoic acid thioester of coenzyme A. (4e,7e)-3-hydroxydeca-4,7-dienoyl-coa is an acyl-CoA with 10 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (4e,7e)-3-hydroxydeca-4,7-dienoyl-coa is therefore classified as a medium chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (4e,7e)-3-hydroxydeca-4,7-dienoyl-coa, being a medium chain acyl-CoA is a substrate for medium chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (4E,7E)-3-Hydroxydeca-4,7-dienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (4E,7E)-3-Hydroxydeca-4,7-dienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (4E,7E)-3-Hydroxydeca-4,7-dienoyl-CoA into (4E_7E)-3-Hydroxydeca-4_7-dienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (4E_7E)-3-Hydroxydeca-4_7-dienoylcarnitine is converted back to (4E,7E)-3-Hydroxydeca-4,7-dienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (4E,7E)-3-Hydroxydeca-4,7-dienoyl-CoA occurs in four steps. First, since (4E,7E)-3-Hydroxydeca-4,7-dienoyl-CoA is a medium chain acyl-CoA it is the substrate for a medium chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (4E,7E)-3-Hydroxydeca-4,7-dienoyl-CoA, creating a double bond between the alpha and beta carbons. FAD ...
(5Z,7E)-3-Hydroxydeca-5,7-dienoyl-CoA
C31H50N7O18P3S (933.2145790000001)
(5z,7e)-3-hydroxydeca-5,7-dienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (5Z_7E)-3-hydroxydeca-5_7-dienoic acid thioester of coenzyme A. (5z,7e)-3-hydroxydeca-5,7-dienoyl-coa is an acyl-CoA with 10 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (5z,7e)-3-hydroxydeca-5,7-dienoyl-coa is therefore classified as a medium chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (5z,7e)-3-hydroxydeca-5,7-dienoyl-coa, being a medium chain acyl-CoA is a substrate for medium chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (5Z,7E)-3-Hydroxydeca-5,7-dienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (5Z,7E)-3-Hydroxydeca-5,7-dienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (5Z,7E)-3-Hydroxydeca-5,7-dienoyl-CoA into (5Z_7E)-3-Hydroxydeca-5_7-dienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (5Z_7E)-3-Hydroxydeca-5_7-dienoylcarnitine is converted back to (5Z,7E)-3-Hydroxydeca-5,7-dienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (5Z,7E)-3-Hydroxydeca-5,7-dienoyl-CoA occurs in four steps. First, since (5Z,7E)-3-Hydroxydeca-5,7-dienoyl-CoA is a medium chain acyl-CoA it is the substrate for a medium chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (5Z,7E)-3-Hydroxydeca-5,7-dienoyl-CoA, creating a double bond between the alpha and beta carbons. FAD ...
CoA 10:2;O
C31H50N7O18P3S (933.2145790000001)
An oxo-fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxylic acid group of (3S)-3-isopropenyl-6-oxoheptanoic acid. An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxylic acid group of 3-isopropenyl-6-oxoheptanoic acid. A 3-hydroxyacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of 2-hydroxy-4-isopropenylcyclohexane-1-carboxylic acid.
(4E,6Z)-3-Hydroxydeca-4,6-dienoyl-CoA
C31H50N7O18P3S (933.2145790000001)
(6Z,8E)-3-Hydroxydeca-6,8-dienoyl-CoA
C31H50N7O18P3S (933.2145790000001)
(4E,7E)-3-Hydroxydeca-4,7-dienoyl-CoA
C31H50N7O18P3S (933.2145790000001)
(5Z,7E)-3-Hydroxydeca-5,7-dienoyl-CoA
C31H50N7O18P3S (933.2145790000001)
(3R)-3-Isopropenyl-6-oxoheptanoyl-CoA; (Acyl-CoA); [M+H]+
C31H50N7O18P3S (933.2145790000001)
(R)-3-hydroxydecanoyl-CoA(4-)
C31H50N7O18P3S (933.2145790000001)
A 3-hydroxy fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (R)-3-hydroxydecanoyl-CoA.
3-hydroxydecanoyl-CoA(4-)
C31H50N7O18P3S (933.2145790000001)
A 3-hydroxy fatty acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate OH groups of 3-hydroxydecanoyl-CoA; major species at pH 7.3.
(S)-3-hydroxydecanoyl-CoA(4-)
C31H50N7O18P3S (933.2145790000001)
An (S)-3-hydroxyacyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate OH groups of (S)-3-hydroxydecanoyl-CoA; major species at pH 7.3.