Chemical Formula: C28H30Cl2N2

Chemical Formula C28H30Cl2N2

Found 1 metabolite its formula value is C28H30Cl2N2

Amn082 dihydrochloride

Amn082 dihydrochloride

C28H30Cl2N2 (464.1786)


AMN082, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 potently inhibits cAMP accumulation and stimulates GTPγS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects[1][2].