Chemical Formula: C21H22Cl2N4O2

Chemical Formula C21H22Cl2N4O2

Found 2 metabolite its formula value is C21H22Cl2N4O2

Ulixertinib

4-{5-chloro-2-[(propan-2-yl)amino]pyridin-4-yl}-N-[1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide

C21H22Cl2N4O2 (432.11197319999997)

Ulixertinib

Ulixertinib (BVD-523)

C21H22Cl2N4O2 (432.11197319999997)

C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C61074 - Serine/Threonine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line[1][2].