Chemical Formula: C21H18O3
Chemical Formula C21H18O3
Found 11 metabolite its formula value is C21H18O3
3-(3,5-DIMETHOXYPHENYL)-1-(2-NAPHTHYL)PROP-2-EN-1-ONE
3-(3,5-DIMETHOXYPHENYL)-1-(2-NAPHTHYL)PROP-2-EN-1-ONE
Benzoic acid,4-(phenylmethoxy)-, phenylmethyl ester
Benzoic acid,4-(phenylmethoxy)-, phenylmethyl ester
(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
LT175, a dual PPARα/γ ligand, is an orally active partial agonist against PPARγ(hPPARα:EC50=0.22 μm; mPPARα:EC50=0.26 μm; hPPARγ:EC50=0.48 μm). LT175 interacts with PPARγ and affects the recruitment of the coregulators cyclic-AMP response element-binding protein-binding protein and nuclear corepressor 1 (NCoR1). LT175 interacts with PPARγ in a hydrophobic region called “diphenyl pocket”. LT175 has potent insulin-sensitizing effects and reduced adipogenic properties[1].
3-(6-Benzyloxy-naphthalen-2-yl)-acrylic acid methyl ester
3-(6-Benzyloxy-naphthalen-2-yl)-acrylic acid methyl ester