Chemical Formula: C18H23NO5
Chemical Formula C18H23NO5
Found 80 metabolite its formula value is C18H23NO5
Spartioidine
Seneciphylline
A pyrrolizine alkaloid that is 13,19-didehydrosenecionane carrying a hydroxy substituent at position 12 and two oxo substituents at positions 11 and 16. CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2297 [Raw Data] CB082b_Seneciphylline_pos_40eV_CB000034.txt [Raw Data] CB082b_Seneciphylline_pos_30eV_CB000034.txt [Raw Data] CB082b_Seneciphylline_pos_20eV_CB000034.txt [Raw Data] CB082b_Seneciphylline_pos_10eV_CB000034.txt [Raw Data] CB082b_Seneciphylline_pos_50eV_CB000034.txt Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica[1]. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities[2].
Seneciphylline
4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
1ST14177
(1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-, (3Z,6R,14aR,14bR)-
Seneciphylline is a white powder. (NTP, 1992) LSM-2853 is a citraconoyl group. Seneciphylline is a natural product found in Senecio bollei, Tussilago farfara, and other organisms with data available. Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica[1]. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities[2].
Sinococuline
(1S,9S,12S,13S)-4,11-DIMETHOXY-17-AZATETRACYCLO(7.5.3.0^(1,10).0^(2,7))HEPTADECA-2(7),3,5,10-TETRAENE-3,12,13-TRIOL
Sinococuline is a natural product found in Cocculus trilobus, Stephania excentrica, and Stephania cephalantha with data available.
4,8-dimethyl-6-O-(2,4-di-O-methyl-beta-D-xylopyranosyl)-hydroxyquinoline|4,8-dimethyl-6-O-(2?,4?-di-O-methyl-beta-D-xylopyranosyl)hydroxyquinoline
4,8-dimethyl-6-O-(2,4-di-O-methyl-beta-D-xylopyranosyl)-hydroxyquinoline|4,8-dimethyl-6-O-(2?,4?-di-O-methyl-beta-D-xylopyranosyl)hydroxyquinoline
1-(4-hydroxy-3-methoxypheny)-2-<(4-hydroxy-3-methoxyphenetyl)amino>ethanol|1-(4-hydroxy-3-methoxypheny)-2-[(4-hydroxy-3-methoxyphenetyl)amino]ethanol
1-(4-hydroxy-3-methoxypheny)-2-<(4-hydroxy-3-methoxyphenetyl)amino>ethanol|1-(4-hydroxy-3-methoxypheny)-2-[(4-hydroxy-3-methoxyphenetyl)amino]ethanol
3-(2-hydroxy-3-methyl-but-3-enyl)-4,7,8-trimethoxy-1-methyl-1H-quinolin-2-one|Isoptelefolin
3-(2-hydroxy-3-methyl-but-3-enyl)-4,7,8-trimethoxy-1-methyl-1H-quinolin-2-one|Isoptelefolin
Convolicine
(8-Acetyl-8-azabicyclo[3.2.1]octan-3-yl) 3,4-dimethoxybenzoate
Origin: Plant; SubCategory_DNP: Alkaloids derived from ornithine, Tropane alkaloids
Seneciphylline
Senenciphylline
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.402 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.399 Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica[1]. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities[2].
(7aS)-7c-(6-hydroxymethyl-benzo[1,3]dioxol-5-yl)-6c-methoxy-1-methyl-(7ar)-2,3,5,6,7,7a-hexahydro-indol-5t-ol|9,10-methanediyldioxy-1,6-dimethyl-6,7-seco-lycoran-4(12)-ene-5alpha,7-diol|Galanthusin|galanthusine|O6-methyl-tetrahydro-hippeastrine
(7aS)-7c-(6-hydroxymethyl-benzo[1,3]dioxol-5-yl)-6c-methoxy-1-methyl-(7ar)-2,3,5,6,7,7a-hexahydro-indol-5t-ol|9,10-methanediyldioxy-1,6-dimethyl-6,7-seco-lycoran-4(12)-ene-5alpha,7-diol|Galanthusin|galanthusine|O6-methyl-tetrahydro-hippeastrine
benzyl 3-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate
benzyl 3-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate
Pentanoic acid, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-4-methyl-, 1,1-dimethylethyl ester, (2R)-
Pentanoic acid, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-4-methyl-, 1,1-dimethylethyl ester, (2R)-
3-Oxo-3-(1-Cbz-Piperidin-4-Yl)-Propionic Acid Ethyl Ester
3-Oxo-3-(1-Cbz-Piperidin-4-Yl)-Propionic Acid Ethyl Ester
5-[[[(5-Tert-butyl-2-methyl-3-furanyl)-oxomethyl]amino]methyl]-2-furancarboxylic acid ethyl ester
5-[[[(5-Tert-butyl-2-methyl-3-furanyl)-oxomethyl]amino]methyl]-2-furancarboxylic acid ethyl ester
(4Z)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione
(4Z)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione
(15E)-12-hydroxy-13,19-didehydrosenecionan-11,16-dione
(15E)-12-hydroxy-13,19-didehydrosenecionan-11,16-dione
2-cyclopentyl 5-methyl 3,6-dimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2,5-dicarboxylate
2-cyclopentyl 5-methyl 3,6-dimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2,5-dicarboxylate
3-hydroxy-7-(hydroxymethyl)-6-methyl-2-[(1E,3E)-nona-1,3-dien-1-yl]-6,7-dihydropyrano[2,3-c]pyrrole-4,5-dione
3-hydroxy-7-(hydroxymethyl)-6-methyl-2-[(1E,3E)-nona-1,3-dien-1-yl]-6,7-dihydropyrano[2,3-c]pyrrole-4,5-dione
Senecionan-11,16-dione, 13,19-didehydro-12-hydroxy-
Senecionan-11,16-dione, 13,19-didehydro-12-hydroxy-
[(5R)-8-acetyl-8-azabicyclo[3.2.1]octan-3-yl] 3,4-dimethoxybenzoate
[(5R)-8-acetyl-8-azabicyclo[3.2.1]octan-3-yl] 3,4-dimethoxybenzoate
pyranonigrin H
pyranonigrin H
A member of the class of pyranopyrroles with formula C18H23NO5, originally isolated from Aspergillus niger.
(1s,12r,14s,15r,16s,17s)-4,5,15-trimethoxy-13-oxa-9-azapentacyclo[7.7.1.0²,⁷.0¹²,¹⁴.0¹²,¹⁷]heptadeca-2(7),3,5-trien-16-ol
(1s,12r,14s,15r,16s,17s)-4,5,15-trimethoxy-13-oxa-9-azapentacyclo[7.7.1.0²,⁷.0¹²,¹⁴.0¹²,¹⁷]heptadeca-2(7),3,5-trien-16-ol
3-{2,4-dihydroxy-5-[(1-hydroxy-7-methylocta-2,4-dien-1-ylidene)amino]phenyl}propanoic acid
3-{2,4-dihydroxy-5-[(1-hydroxy-7-methylocta-2,4-dien-1-ylidene)amino]phenyl}propanoic acid
4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-15-ene-3,8-dione
4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-15-ene-3,8-dione
(1r,8s,10s,11r,12r)-4-methoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.1⁸,¹¹.0¹,¹⁰.0²,⁷]octadeca-2,4,6-triene-3,11,12-triol
(1r,8s,10s,11r,12r)-4-methoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.1⁸,¹¹.0¹,¹⁰.0²,⁷]octadeca-2,4,6-triene-3,11,12-triol
(1r,3r,5s)-8-acetyl-8-azabicyclo[3.2.1]octan-3-yl 3,4-dimethoxybenzoate
(1r,3r,5s)-8-acetyl-8-azabicyclo[3.2.1]octan-3-yl 3,4-dimethoxybenzoate
8-acetyl-8-azabicyclo[3.2.1]octan-3-yl 3,4-dimethoxybenzoate
8-acetyl-8-azabicyclo[3.2.1]octan-3-yl 3,4-dimethoxybenzoate
(1r,4e,7r,17r)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
(1r,4e,7r,17r)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
(2s,3r,4s,5r)-2-[(4,8-dimethylquinolin-6-yl)oxy]-3,5-dimethoxyoxan-4-ol
(2s,3r,4s,5r)-2-[(4,8-dimethylquinolin-6-yl)oxy]-3,5-dimethoxyoxan-4-ol
2',3',4-trimethoxy-10'-azaspiro[cyclopentane-1,7'-tricyclo[4.3.3.0¹,⁶]dodecane]-2',3-diene-4',5-dione
2',3',4-trimethoxy-10'-azaspiro[cyclopentane-1,7'-tricyclo[4.3.3.0¹,⁶]dodecane]-2',3-diene-4',5-dione
18-methoxy-15-methyl-5,7,12-trioxa-15-azapentacyclo[11.7.0.0¹,¹⁶.0²,¹⁰.0⁴,⁸]icosa-2,4(8),9-trien-13-ol
18-methoxy-15-methyl-5,7,12-trioxa-15-azapentacyclo[11.7.0.0¹,¹⁶.0²,¹⁰.0⁴,⁸]icosa-2,4(8),9-trien-13-ol
(3s,5s)-3-hydroxy-5-{[2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methyl}-1,3-dimethylpyrrolidine-2,4-dione
(3s,5s)-3-hydroxy-5-{[2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methyl}-1,3-dimethylpyrrolidine-2,4-dione
(1r,4e,7r,17s)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
(1r,4e,7r,17s)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
7-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-2,3,5,6,7,7a-hexahydroindol-5-ol
7-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-2,3,5,6,7,7a-hexahydroindol-5-ol
4,5,15-trimethoxy-13-oxa-9-azapentacyclo[7.7.1.0²,⁷.0¹²,¹⁴.0¹²,¹⁷]heptadeca-2(7),3,5-trien-16-ol
4,5,15-trimethoxy-13-oxa-9-azapentacyclo[7.7.1.0²,⁷.0¹²,¹⁴.0¹²,¹⁷]heptadeca-2(7),3,5-trien-16-ol
(1s,13s,16r,18s)-18-methoxy-15-methyl-5,7,12-trioxa-15-azapentacyclo[11.7.0.0¹,¹⁶.0²,¹⁰.0⁴,⁸]icosa-2,4(8),9-trien-13-ol
(1s,13s,16r,18s)-18-methoxy-15-methyl-5,7,12-trioxa-15-azapentacyclo[11.7.0.0¹,¹⁶.0²,¹⁰.0⁴,⁸]icosa-2,4(8),9-trien-13-ol
3a-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-3,6,7,7a-tetrahydro-2h-indol-3-ol
3a-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-3,6,7,7a-tetrahydro-2h-indol-3-ol
4,5,14-trimethoxy-9-azatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-2(7),3,5,11-tetraene-13,15-diol
4,5,14-trimethoxy-9-azatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-2(7),3,5,11-tetraene-13,15-diol
5,11-dimethoxy-17-azatetracyclo[7.5.3.0¹,¹⁰.0²,⁷]heptadeca-2,4,6,10-tetraene-4,12,13-triol
5,11-dimethoxy-17-azatetracyclo[7.5.3.0¹,¹⁰.0²,⁷]heptadeca-2,4,6,10-tetraene-4,12,13-triol
(1r,4z,7s,11r,17r)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-15-ene-3,8-dione
(1r,4z,7s,11r,17r)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-15-ene-3,8-dione
3-hydroxy-5-{[2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methyl}-1,3-dimethylpyrrolidine-2,4-dione
3-hydroxy-5-{[2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methyl}-1,3-dimethylpyrrolidine-2,4-dione
4-methoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.1⁸,¹¹.0¹,¹⁰.0²,⁷]octadeca-2,4,6-triene-3,11,12-triol
4-methoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.1⁸,¹¹.0¹,¹⁰.0²,⁷]octadeca-2,4,6-triene-3,11,12-triol
(1s,9s,12s,13s)-5,11-dimethoxy-17-azatetracyclo[7.5.3.0¹,¹⁰.0²,⁷]heptadeca-2,4,6,10-tetraene-4,12,13-triol
(1s,9s,12s,13s)-5,11-dimethoxy-17-azatetracyclo[7.5.3.0¹,¹⁰.0²,⁷]heptadeca-2,4,6,10-tetraene-4,12,13-triol
(2z,5s,7r,8s,9r)-15,16-dimethoxy-18-oxa-10-azatetracyclo[7.7.1.1²,⁸.0¹³,¹⁷]octadeca-1(16),2,13(17),14-tetraene-5,7-diol
(2z,5s,7r,8s,9r)-15,16-dimethoxy-18-oxa-10-azatetracyclo[7.7.1.1²,⁸.0¹³,¹⁷]octadeca-1(16),2,13(17),14-tetraene-5,7-diol
15,16-dimethoxy-18-oxa-10-azatetracyclo[7.7.1.1²,⁸.0¹³,¹⁷]octadeca-1(16),2,13(17),14-tetraene-5,7-diol
15,16-dimethoxy-18-oxa-10-azatetracyclo[7.7.1.1²,⁸.0¹³,¹⁷]octadeca-1(16),2,13(17),14-tetraene-5,7-diol
(1s,4e,7r)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
(1s,4e,7r)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
(1r,8s,10s,11r,12s)-4-methoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.1⁸,¹¹.0¹,¹⁰.0²,⁷]octadeca-2,4,6-triene-3,11,12-triol
(1r,8s,10s,11r,12s)-4-methoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.1⁸,¹¹.0¹,¹⁰.0²,⁷]octadeca-2,4,6-triene-3,11,12-triol
3-(2,4-dihydroxy-5-{[(2e,4e)-1-hydroxy-7-methylocta-2,4-dien-1-ylidene]amino}phenyl)propanoic acid
3-(2,4-dihydroxy-5-{[(2e,4e)-1-hydroxy-7-methylocta-2,4-dien-1-ylidene]amino}phenyl)propanoic acid
(3s,3as,6s,7as)-3a-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-3,6,7,7a-tetrahydro-2h-indol-3-ol
(3s,3as,6s,7as)-3a-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-3,6,7,7a-tetrahydro-2h-indol-3-ol
3-[(2r)-2-hydroxy-3-methylbut-3-en-1-yl]-4,6,8-trimethoxy-1-methylquinolin-2-one
3-[(2r)-2-hydroxy-3-methylbut-3-en-1-yl]-4,6,8-trimethoxy-1-methylquinolin-2-one
(1s,13r,14r,15s,16s)-4,5,14-trimethoxy-9-azatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-2(7),3,5,11-tetraene-13,15-diol
(1s,13r,14r,15s,16s)-4,5,14-trimethoxy-9-azatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-2(7),3,5,11-tetraene-13,15-diol
8,11-dimethoxy-1h,2h,4h,5h,10h,11h,12h-indolo[7a,1-a]isoquinoline-5,7,12-triol
8,11-dimethoxy-1h,2h,4h,5h,10h,11h,12h-indolo[7a,1-a]isoquinoline-5,7,12-triol
(1r,4z,7s,17s)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
(1r,4z,7s,17s)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
2-[(4,8-dimethylquinolin-6-yl)oxy]-3,5-dimethoxyoxan-4-ol
2-[(4,8-dimethylquinolin-6-yl)oxy]-3,5-dimethoxyoxan-4-ol
(1r,4z,7r,17s)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
(1r,4z,7r,17s)-4-ethylidene-7-hydroxy-7-methyl-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione
6-methoxy-3-{6-methoxy-2,4-dioxabicyclo[3.3.1]nona-1(9),5,7-trien-7-yl}-1-methyl-3a,6,7,7a-tetrahydro-2h-indol-3-ol
6-methoxy-3-{6-methoxy-2,4-dioxabicyclo[3.3.1]nona-1(9),5,7-trien-7-yl}-1-methyl-3a,6,7,7a-tetrahydro-2h-indol-3-ol
(3r,3as,6s,7as)-3a-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-3,6,7,7a-tetrahydro-2h-indol-3-ol
(3r,3as,6s,7as)-3a-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-3,6,7,7a-tetrahydro-2h-indol-3-ol
(2s)-3-hydroxy-1-(4-methoxy-1-methyl-2-oxoquinolin-3-yl)-3-methylbutan-2-yl acetate
(2s)-3-hydroxy-1-(4-methoxy-1-methyl-2-oxoquinolin-3-yl)-3-methylbutan-2-yl acetate
3-(2-hydroxy-3-methylbut-3-en-1-yl)-4,6,8-trimethoxy-1-methylquinolin-2-one
3-(2-hydroxy-3-methylbut-3-en-1-yl)-4,6,8-trimethoxy-1-methylquinolin-2-one
(5r,6r,7s,7as)-7-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-2,3,5,6,7,7a-hexahydroindol-5-ol
(5r,6r,7s,7as)-7-[6-(hydroxymethyl)-2h-1,3-benzodioxol-5-yl]-6-methoxy-1-methyl-2,3,5,6,7,7a-hexahydroindol-5-ol
(3s,5s)-3-hydroxy-5-{[(2s)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methyl}-1,3-dimethylpyrrolidine-2,4-dione
(3s,5s)-3-hydroxy-5-{[(2s)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methyl}-1,3-dimethylpyrrolidine-2,4-dione
(5s,9bs,11r,12s)-8,11-dimethoxy-1h,2h,4h,5h,10h,11h,12h-indolo[7a,1-a]isoquinoline-5,7,12-triol
(5s,9bs,11r,12s)-8,11-dimethoxy-1h,2h,4h,5h,10h,11h,12h-indolo[7a,1-a]isoquinoline-5,7,12-triol