Exact Mass: 895.4493

Exact Mass Matches: 895.4493

Found 3 metabolites which its exact mass value is equals to given mass value 895.4493, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Biie-0246

5-Carbamimidamido-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[(1-hydroxy-2-{1-[2-(4-{10-hydroxy-9-azatricyclo[9.4.0.0,]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-yl}piperazin-1-yl)-2-oxoethyl]cyclopentyl}ethylidene)amino]pentanimidate

C49H57N11O6 (895.4493)


   

5-(diaminomethylideneamino)-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[[2-[1-[2-oxo-2-[4-(6-oxo-5,11-dihydrobenzo[c][1]benzazepin-11-yl)piperazin-1-yl]ethyl]cyclopentyl]acetyl]amino]pentanamide

5-(diaminomethylideneamino)-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[[2-[1-[2-oxo-2-[4-(6-oxo-5,11-dihydrobenzo[c][1]benzazepin-11-yl)piperazin-1-yl]ethyl]cyclopentyl]acetyl]amino]pentanamide

C49H57N11O6 (895.4493)


   

BIIE-0246

BIIE-0246

C49H57N11O6 (895.4493)


BIIE-0246 (AR-H 053591) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [125I]PYY3-36. BIIE-0246 decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 reduces albuminuria in ADR nephropathy[1][2][3].