Exact Mass: 691.2691937999999
Exact Mass Matches: 691.2691937999999
Found 105 metabolites which its exact mass value is equals to given mass value 691.2691937999999,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Maytansine
D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent C274 - Antineoplastic Agent > C1931 - Antineoplastic Plant Product C1907 - Drug, Natural Product Same as: D04864 Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations[1].
Alpha-Tetrasaccharide
Alpha-Tetrasaccharide is a metabolite that accumulates in the urine of glucosidase I deficient patients, a defect due to missense mutations in the glucosidase I gene. (PMID 10788335). A tetrasaccharide is a carbohydrate which gives upon hydrolysis four molecules of the same or different monosaccharides. For example, stachyose upon hydrolysis gives one molecule each of glucose and fructose and two molecules of galactose. The general formula of a tetrasaccharide is typically C24H42O21. (Wikipedia). Alpha-Tetrasaccharide is a metabolite that accumulates in the urine of glucosidase I deficiency patients, a defect due to missense mutations in the glucosidase I gene. (PMID 10788335)
Blood group B type 1 tetrasaccharide
Maitansine
Noa-Asn-Apns-Dmt-NH-tBu
3beta-O-propionyl-5alpha-O-benzoyl-7beta-O-acetyl-17-O-nicotinoylpremyrsinol|euphorbialoid A
Maitansine
Maytansine is an organic heterotetracyclic compound and 19-membered macrocyclic lactam antibiotic originally isolated from the Ethiopian shrub Maytenus serrata but also found in other Maytenus species. It exhibits cytotoxicity against many tumour cell lines. It has a role as a plant metabolite, an antimicrobial agent, an antineoplastic agent, a tubulin modulator and an antimitotic. It is an epoxide, a carbamate ester, an organochlorine compound, an alpha-amino acid ester, an organic heterotetracyclic compound and a maytansinoid. Maytansine is a natural product found in Putterlickia verrucosa and Gymnosporia diversifolia with data available. Maytansine is an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata. Maytansine binds to tubulin at the rhizoxin binding site, thereby inhibiting microtubule assembly, inducing microtubule disassembly, and disrupting mitosis. Maytansine exhibits cytotoxicity against many tumor cell lines and may inhibit tumor growth in vivo. (NCI04) An ansa macrolide isolated from the MAYTENUS genus of East African shrubs. An organic heterotetracyclic compound and 19-membered macrocyclic lactam antibiotic originally isolated from the Ethiopian shrub Maytenus serrata but also found in other Maytenus species. It exhibits cytotoxicity against many tumour cell lines. C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators C274 - Antineoplastic Agent > C1931 - Antineoplastic Plant Product D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents C1907 - Drug, Natural Product Same as: D04864 Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations[1].
Asp Trp Trp Trp
Trp Asp Trp Trp
Trp Trp Asp Trp
Trp Trp Trp Asp
2-[4-[2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-1-yl]-1-morpholin-4-ylethanone
C37H43Cl2N5O4 (691.2691937999999)
O-6-Deoxy-alpha-L-galactopyranosyl-(1-2)-O-[alpha-D-galactopyranosyl-(1-3)]-O-beta-D-galactopyranosyl-(1-3)-2-(acetylamino)-2-deoxy-D-galactose
O-2-(Acetylamino)-2-deoxy-alpha-D-galactopyranosyl-(1-3)-O-[6-deoxy-alpha-L-galactopyranosyl-(1-2)]-O-beta-D-galactopyranosyl-(1-4)-D-galactose
O-6-Deoxy-alpha-L-galactopyranosyl-(1-2)-O-beta-D-galactopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-D-galactose
O-6-Deoxy-alpha-L-galactopyranosyl-(1-2)-O-[alpha-D-galactopyranosyl-(1-3)]-O-beta-D-galactopyranosyl-(1-3)-2-(acetylamino)-2-deoxy-D-glucose
O-alpha-L-Fucopyranosyl-(1 - 2)-O-[alpha-D-galactopyranosyl-(1 - 3)]-O-beta-D-galactopyranosyl-(1 - 4)-2-acetamido-2-deoxy-D-glucopyranose
(3S)-3-methylsulfanyl-1-[2-[4-[4-(1-methyl-1,2,4-triazol-3-yl)phenyl]-3,6-dihydro-2H-pyridin-1-yl]-2-oxoethyl]-N-[3-(6-propan-2-yloxypyridin-3-yl)-1H-indazol-5-yl]pyrrolidine-3-carboxamide
MK-8353 (SCH900353) is a potent, selective and orally available ERK1/2 inhibitor, with IC50s of 23.0 nM and 8.8 nM, respectively; MK-8353 has antitumor activity.