Exact Mass: 645.2911
Exact Mass Matches: 645.2911
Found 143 metabolites which its exact mass value is equals to given mass value 645.2911,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Aconitine
D049990 - Membrane Transport Modulators > D062687 - Sodium Channel Agonists > D061585 - Voltage-Gated Sodium Channel Agonists D007155 - Immunologic Factors Aconitine is a diterpenoid that is 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diol having acetate and benzoate groups at the 8- and 14-positions respectively. It is functionally related to an aconitane. Aconitine is a natural product found in Aconitum anthora, Aconitum napellus, and other organisms with data available. Aconitine is a plant toxin found in species of wolfsbane (Aconitum genus). It is a neurotoxin previously used as an antipyretic and analgesic, and still has some limited application in herbal medicine. (L1235). The toxic effects of Aconitine have been tested in a variety of different test animals, including mammals (dog, cat, guinea pig, mouse, rat and rabbit), frogs and pigeons. Depending on the route of exposure, the observed toxic effects were: local anesthetic effect, diarrhea, convulsions, arrhythmias or death. According to a review of different reports of aconite poisoning in humans the following clinical features were observed: Neurological, Cardiovascular, Ventricular arrhythmias, Gastrointestinal. A C19 norditerpenoid alkaloid (DITERPENES) from the root of ACONITUM; DELPHINIUM and larkspurs. It activates VOLTAGE-GATED SODIUM CHANNELS. It has been used to induce ARRHYTHMIAS in experimental animals and it has anti-inflammatory and anti-neuralgic properties. See also: Aconitum coreanum root (part of). Origin: Plant; SubCategory_DNP: Terpenoid alkaloids, Diterpene alkaloid, Aconitum alkaloid Annotation level-1 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2309
Acarbose
Acarbose is a tetrasaccharide derivative consisting of a dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl C7 cyclitol moiety [called valienol (or valienamine)] linked via nitrogen to isomaltotriose. It has a role as an EC 3.2.1.20 (alpha-glucosidase) inhibitor, an EC 3.2.1.1 (alpha-amylase) inhibitor, a hypoglycemic agent and a geroprotector. It is a conjugate base of an acarbose(1+). Acarbose is an alpha glucosidase inhibitor which decreases intestinal absorption of carbohydrates and is used as an adjunctive therapy in the management of type 2 diabetes. Acarbose has been linked to rare instances of clinically apparent acute liver injury. Acarbose is a natural product found in Streptomyces glaucescens, Streptomyces coelicoflavus, and other organisms with data available. Acarbose is a pseudotetrasaccharide and inhibitor of alpha-glucosidase and pancreatic alpha-amylase with antihyperglycemic activity. Acarbose binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. In addition, acarbose inhibits pancreatic alpha-amylase which hydrolyzes complex starches to oligosaccharides in the small intestines. An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE. An inhibitor of alpha glucosidase that retards the digestion and absorption of carbohydrates in the small intestine and hence reduces the increase in blood-glucose concentrations after a carbohydrate load. It is given orally to non-insulin dependent diabetes mellitus patients where diet modification or oral hypoglycemic agents do not control their condition. (From Martindale The Extra Pharmacopoeia, 31st ed) A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BF - Alpha glucosidase inhibitors D007004 - Hypoglycemic Agents > D065089 - Glycoside Hydrolase Inhibitors D004791 - Enzyme Inhibitors Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin[1][2][3].
Sterecyt
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AA - Nitrogen mustard analogues D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents
S-(11-hydroxy-9-deoxy-delta12-PGD2)-glutathione
S-(11-hydroxy-9-deoxy-delta12-PGD2)-glutathione is the glutathione conjugate of S-(11-hydroxy-9-deoxy-delta12-PGD2) [HMDB] S-(11-hydroxy-9-deoxy-delta12-PGD2)-glutathione is the glutathione conjugate of S-(11-hydroxy-9-deoxy-delta12-PGD2).
S-(9-hydroxy-PGA1)-glutathione
S-(9-hydroxy-PGA1)-glutathione is the glutathione conjugate of S-(9-hydroxy-PGA1). Avian red cells metabolize PGA, to 9-hydroxyl PGA1-GSH, presumably by the combined actions of glutathione-S-transferase (or ligandin) and prostaglandin 9-keto reductase(4, 12). Since conversion of PGAl to the polar metabolite is rapid and nearly complete, PGA1-GSH is the form is which PGAl acts to inhibit cAMP export by avian red cells. S-(9-hydroxy-PGA1)-glutathione is the glutathione conjugate of S-(9-hydroxy-PGA1)
Acarbosa
Aconitinum
Alpha-Acarbose
A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BF - Alpha glucosidase inhibitors D007004 - Hypoglycemic Agents > D065089 - Glycoside Hydrolase Inhibitors D004791 - Enzyme Inhibitors
Prednimustine
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AA - Nitrogen mustard analogues D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents
Euphoheliosnoid A
[(1S,2R,3aR,4R,5R,6E,11R,12E,13aS)-3a,4-diacetyloxy-1-benzoyloxy-2,5,8,8,12-pentamethyl-9-oxo-1,2,3,4,5,10,11,13a-octahydrocyclopenta[12]annulen-11-yl] pyridine-3-carboxylate is a natural product found in Euphorbia helioscopia with data available.
(?)-(A-b)-8beta-acetoxy-14alpha-benzoyloxy-N-ethyl-3alpha,10beta,13beta-trihydroxy-1alpha,6alpha,16beta,18-tetramethoxyaconitane
Acarbose
Acarbose is a tetrasaccharide derivative consisting of a dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl C7 cyclitol moiety [called valienol (or valienamine)] linked via nitrogen to isomaltotriose. It has a role as an EC 3.2.1.20 (alpha-glucosidase) inhibitor, an EC 3.2.1.1 (alpha-amylase) inhibitor, a hypoglycemic agent and a geroprotector. It is a conjugate base of an acarbose(1+). Acarbose is an alpha glucosidase inhibitor which decreases intestinal absorption of carbohydrates and is used as an adjunctive therapy in the management of type 2 diabetes. Acarbose has been linked to rare instances of clinically apparent acute liver injury. Acarbose is a natural product found in Streptomyces glaucescens, Streptomyces coelicoflavus, and other organisms with data available. Acarbose is a pseudotetrasaccharide and inhibitor of alpha-glucosidase and pancreatic alpha-amylase with antihyperglycemic activity. Acarbose binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. In addition, acarbose inhibits pancreatic alpha-amylase which hydrolyzes complex starches to oligosaccharides in the small intestines. An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE. A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BF - Alpha glucosidase inhibitors D007004 - Hypoglycemic Agents > D065089 - Glycoside Hydrolase Inhibitors D004791 - Enzyme Inhibitors C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent C471 - Enzyme Inhibitor > C2846 - Glucosidase Inhibitor Origin: Microbe, Polysaccharides Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin[1][2][3].
OXONITINE
A diterpene alkaloid with formula C33H43NO12, originally isolated from Aconitum carmichaeli.
Asp Trp Tyr Tyr
Asp Tyr Trp Tyr
Asp Tyr Tyr Trp
Glu Arg Arg Trp
Glu Arg Trp Arg
Glu Trp Arg Arg
Phe Phe Phe Trp
Phe Phe Trp Phe
Phe Met Trp Tyr
Phe Met Tyr Trp
Phe Trp Phe Phe
Phe Trp Met Tyr
Phe Trp Tyr Met
Phe Tyr Met Trp
Phe Tyr Trp Met
Met Phe Trp Tyr
Met Phe Tyr Trp
Met Trp Phe Tyr
Met Trp Tyr Phe
Met Tyr Phe Trp
Met Tyr Trp Phe
Arg Glu Arg Trp
Arg Glu Trp Arg
Arg Arg Glu Trp
Arg Arg Trp Glu
Arg Val Trp Trp
Arg Trp Glu Arg
Arg Trp Arg Glu
Arg Trp Val Trp
Arg Trp Trp Val
Val Arg Trp Trp
Val Trp Arg Trp
Val Trp Trp Arg
Trp Asp Tyr Tyr
Trp Glu Arg Arg
Trp Phe Phe Phe
Trp Phe Met Tyr
Trp Phe Tyr Met
Trp Met Phe Tyr
Trp Met Tyr Phe
Trp Arg Glu Arg
Trp Arg Arg Glu
Trp Arg Val Trp
Trp Arg Trp Val
Trp Val Arg Trp
Trp Val Trp Arg
Trp Trp Arg Val
Trp Trp Val Arg
Trp Tyr Asp Tyr
Trp Tyr Phe Met
Trp Tyr Met Phe
Trp Tyr Tyr Asp
Tyr Asp Trp Tyr
Tyr Asp Tyr Trp
Tyr Phe Met Trp
Tyr Phe Trp Met
Tyr Met Phe Trp
Tyr Met Trp Phe
Tyr Trp Asp Tyr
Tyr Trp Phe Met
Tyr Trp Met Phe
Tyr Trp Tyr Asp
Tyr Tyr Asp Trp
Tyr Tyr Trp Asp
[3-(9H-Carbazol-4-yloxy)-2-hydroxy]propyl Carvedilol
β-Alanine, N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-, ethyl ester, tetrahydrate
(3R,4R,6R)-5-[(3R,4R,6R)-5-[(3R,4S,6R)-3,4-Dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol
A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BF - Alpha glucosidase inhibitors
Glucobay
A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BF - Alpha glucosidase inhibitors D007004 - Hypoglycemic Agents > D065089 - Glycoside Hydrolase Inhibitors D004791 - Enzyme Inhibitors
8-(Acetyloxy)-20-formyl-3,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitan-14alpha-yl benzoate
2-(7Z,10Z,13Z,16Z,19Z-docosapentaenoyl)-sn-glycero-3-phospho-1D-myo-inositol
[(1S,9R,10R,13R,14R,16S,17S,18R)-8-acetyloxy-11-formyl-5,7,14-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate
Prednimustine
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AA - Nitrogen mustard analogues D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents
Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle)
Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) (Azido-c(RGDyK)) is a polypeptide composed of arginine, glycine, aspartic acid, and tyrosine that can be used for Synthesis of [18F]FPyKYNE-c(RGDyK)[1].
(1s,2r,3r,4r,5r,6s,7s,8s,9r,10r,13s,15s,16r,17r,18s)-8-(acetyloxy)-11-ethyl-5,7,15-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecan-4-yl benzoate
(2r,3s,3as,6r,12r,13r,13ar)-13,13a-bis(acetyloxy)-3-(benzoyloxy)-2,5,9,9,12-pentamethyl-8-oxo-1h,2h,3h,3ah,6h,7h,12h,13h-cyclopenta[12]annulen-6-yl pyridine-3-carboxylate
(2r,5s,6r)-5-{[(5s,6r)-5-{[(2r,3r,6r)-3,4-dihydroxy-6-methyl-5-{[(4r)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-2,3,4-triol
(1s,2r,3r,4r,5r,6s,7s,8r,9r,10r,13s,15s,16r,17r,18r)-8-(acetyloxy)-11-ethyl-5,7,15-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecan-4-yl benzoate
(1s,2s,3r,4s,5r,6s,7r,8r,9r,10r,13r,14r,16s,17s,18s)-8-(acetyloxy)-11-ethyl-5,7,14-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecan-4-yl benzoate
4-methylaconitane-1,6,8,10,13,14,15,16,18-nonol; (1α,6α,14α,15α,16β)-form,o6,o16,o18-tri-me,14-benzoyl,8,n-di-ac
{"Ingredient_id": "HBIN010681","Ingredient_name": "4-methylaconitane-1,6,8,10,13,14,15,16,18-nonol; (1\u03b1,6\u03b1,14\u03b1,15\u03b1,16\u03b2)-form,o6,o16,o18-tri-me,14-benzoyl,8,n-di-ac","Alias": "NA","Ingredient_formula": "C33H43NO12","Ingredient_Smile": "NA","Ingredient_weight": "645.69","OB_score": "NA","CAS_id": "125263-91-4","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7781","PubChem_id": "NA","DrugBank_id": "NA"}
