Exact Mass: 554.1154522

Exact Mass Matches: 554.1154522

Found 1 metabolites which its exact mass value is equals to given mass value 554.1154522, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

GSK837149A

GSK837149A

C23H22N8O5S2 (554.1154522)


GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer[1][2].