Exact Mass: 554.1154522

Exact Mass Matches: 554.1154522

Found 1 metabolites which its exact mass value is equals to given mass value 554.1154522, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

GSK837149A

GSK837149A

C23H22N8O5S2 (554.1154522)


GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer[1][2].