Chemical Formula: C23H22N8O5S2

Chemical Formula C23H22N8O5S2

Found 1 metabolite its formula value is C23H22N8O5S2

GSK837149A

GSK837149A

C23H22N8O5S2 (554.1154522)


GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer[1][2].