Exact Mass: 552.273
Exact Mass Matches: 552.273
Found 219 metabolites which its exact mass value is equals to given mass value 552.273
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within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Handelin
Handelin is a sesterterpenoid. [(1R,2R,3R,3aR,4S,5S,6R,6aR,9S,9aR,9bR,10S,11R)-2,6-dihydroxy-2,6,9,11-tetramethyl-6-methylidene-2,7-dioxospiro[4,5,6a,7,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-3,15-8-oxatetracyclo[9.2.2.01,10.05,9]pentadec-12-ene]-4-yl] acetate is a natural product found in Tanacetum vulgare, Chrysanthemum lavandulifolium, and other organisms with data available. Handelin is a guaianolide dimer from Chrysanthemum boreale that has potent anti-inflammatory activity by down-regulating NF-κB signaling and pro-inflammatory cytokine production[1]. Handelin is a guaianolide dimer from Chrysanthemum boreale that has potent anti-inflammatory activity by down-regulating NF-κB signaling and pro-inflammatory cytokine production[1].
D-Phenylalanyl-L-2-piperidinecarbonyl-N-(4-nitro phenyl)-L-argininamide
PA(2:0/PGF1alpha)
PA(2:0/PGF1alpha) is an oxidized phosphatidic acid (PA). Oxidized phosphatidic acids are glycerophospholipids in which a phosphate moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidic acids belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidic acids can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PA(2:0/PGF1alpha), in particular, consists of one chain of one acetyl at the C-1 position and one chain of Prostaglandin F1alpha at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PAs can be synthesized via three different routes. In one route, the oxidized PA is synthetized de novo following the same mechanisms as for PAs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PA backbone, mainly through the action of LOX (PMID: 33329396).
PA(PGF1alpha/2:0)
PA(PGF1alpha/2:0) is an oxidized phosphatidic acid (PA). Oxidized phosphatidic acids are glycerophospholipids in which a phosphate moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidic acids belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidic acids can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PA(PGF1alpha/2:0), in particular, consists of one chain of one Prostaglandin F1alpha at the C-1 position and one chain of acetyl at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PAs can be synthesized via three different routes. In one route, the oxidized PA is synthetized de novo following the same mechanisms as for PAs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PA backbone, mainly through the action of LOX (PMID: 33329396).
Euhorbiasteroid
Euphorbiasteroid is a natural product found in Macaranga tanarius and Euphorbia lathyris with data available.
EFL1 diterpene
11-O-trans-Cinnamoyl-12-O-acetyl-17alphaH-marsdenin
16beta-hydroxy-heteroclitalactone H|heteroclitalactone I
2-O-pentadecanoyl-2-hydroxy-8-methoxy-6,7-methylenedioxyisoflavone|aervin D
3,4,5-trihydroxydrhydro-alpha-ionol-9-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside
Phe His His Ile
Phe His His Leu
Phe His Ile His
Phe His Leu His
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Phe Lys Met Gln
Phe Lys Gln Met
Phe Leu His His
Phe Met Lys Gln
Phe Met Gln Lys
Phe Gln Lys Met
Phe Gln Met Lys
Gly Lys Trp Tyr
Gly Lys Tyr Trp
Gly Trp Lys Tyr
Gly Trp Tyr Lys
Gly Tyr Lys Trp
Gly Tyr Trp Lys
His Phe His Ile
His Phe His Leu
His Phe Ile His
His Phe Leu His
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His His Ile Phe
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His Ile Phe His
His Ile His Phe
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Ile Phe His His
Ile His Phe His
Ile His His Phe
Lys Phe Met Gln
Lys Phe Gln Met
Lys Gly Trp Tyr
Lys Gly Tyr Trp
Lys Met Phe Gln
Lys Met Gln Phe
Lys Gln Phe Met
Lys Gln Met Phe
Lys Trp Gly Tyr
Lys Trp Tyr Gly
Lys Tyr Gly Trp
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Leu Phe His His
Leu His Phe His
Leu His His Phe
Met Phe Lys Gln
Met Phe Gln Lys
Met Lys Phe Gln
Met Lys Gln Phe
Met Gln Phe Lys
Met Gln Lys Phe
Asn Arg Thr Tyr
Asn Arg Tyr Thr
Asn Thr Arg Tyr
Asn Thr Tyr Arg
Asn Tyr Arg Thr
Asn Tyr Thr Arg
Gln Phe Lys Met
Gln Phe Met Lys
Gln Lys Phe Met
Gln Lys Met Phe
Gln Met Phe Lys
Gln Met Lys Phe
Gln Arg Ser Tyr
Gln Arg Tyr Ser
Gln Ser Arg Tyr
Gln Ser Tyr Arg
Gln Tyr Arg Ser
Gln Tyr Ser Arg
Arg Asn Thr Tyr
Arg Asn Tyr Thr
Arg Gln Ser Tyr
Arg Gln Tyr Ser
Arg Ser Gln Tyr
Arg Ser Tyr Gln
Arg Thr Asn Tyr
Arg Thr Tyr Asn
Arg Tyr Asn Thr
Arg Tyr Gln Ser
Arg Tyr Ser Gln
Arg Tyr Thr Asn
Ser Gln Arg Tyr
Ser Gln Tyr Arg
Ser Arg Gln Tyr
Ser Arg Tyr Gln
Ser Tyr Gln Arg
Ser Tyr Arg Gln
Thr Asn Arg Tyr
Thr Asn Tyr Arg
Thr Arg Asn Tyr
Thr Arg Tyr Asn
Thr Tyr Asn Arg
Thr Tyr Arg Asn
Trp Gly Lys Tyr
Trp Gly Tyr Lys
Trp Lys Gly Tyr
Trp Lys Tyr Gly
Trp Tyr Gly Lys
Trp Tyr Lys Gly
Tyr Gly Lys Trp
Tyr Gly Trp Lys
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Tyr Asn Arg Thr
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Tyr Gln Arg Ser
Tyr Gln Ser Arg
Tyr Arg Asn Thr
Tyr Arg Gln Ser
Tyr Arg Ser Gln
Tyr Arg Thr Asn
Tyr Ser Gln Arg
Tyr Ser Arg Gln
Tyr Thr Asn Arg
Tyr Thr Arg Asn
Tyr Trp Gly Lys
Tyr Trp Lys Gly
LEE011 succinate
C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C2185 - Cyclin-Dependent Kinase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent