EFL1 diterpene (BioDeep_00000230433)

   


代谢物信息卡片


[(3Z)-1,11-diacetyloxy-3,6,6,14-tetramethyl-2-oxospiro[oxirane-2,10-tricyclo[10.3.0.05,7]pentadec-3-ene]-13-yl] 2-phenylacetate

化学式: C32H40O8 (552.2723040000001)
中文名称: 大戟因子L1, 千金子甾醇, 大戟因子 L1
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC2(C(C1OC(=O)CC3=CC=CC=C3)C(C4(CCC5C(C5(C)C)C=C(C2=O)C)CO4)OC(=O)C)OC(=O)C
InChI: InChI=1S/C32H40O8/c1-18-14-24-23(30(24,5)6)12-13-31(17-37-31)29(38-20(3)33)26-27(39-25(35)15-22-10-8-7-9-11-22)19(2)16-32(26,28(18)36)40-21(4)34/h7-11,14,19,23-24,26-27,29H,12-13,15-17H2,1-6H3

描述信息

同义名列表

5 个代谢物同义名

(1,11-Diacetyloxy-3,6,6,14-tetramethyl-2-oxospiro[oxirane-2,10-tricyclo[10.3.0.05,7]pentadec-3-ene]-13-yl) 2-phenylacetate; euphorbia factor L1; Euphorbiasteroid; EFL1 diterpene; [(3Z)-1,11-diacetyloxy-3,6,6,14-tetramethyl-2-oxospiro[oxirane-2,10-tricyclo[10.3.0.05,7]pentadec-3-ene]-13-yl] 2-phenylacetate



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Dongjing Jiang, XiaoQin Gao, RuLan Tan, Xun Liu, Ye Zhu, Li Zhang. Euphorbia factor L1 suppresses breast cancer liver metastasis via DDR1-mediated immune infiltration. Aging. 2023 Sep; 15(?):. doi: 10.18632/aging.205030. [PMID: 37709489]
  • Lingyue Zou, Wenqiang Bao, Yadong Gao, Mengting Chen, Yajiao Wu, Shuo Wang, Chutao Li, Jian Zhang, Dongcheng Zhang, Qi Wang, An Zhu. Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of Euphorbia Factors toward Human Colon Adenocarcinoma Cell Line Caco-2. Molecules (Basel, Switzerland). 2022 Oct; 27(20):. doi: 10.3390/molecules27206931. [PMID: 36296525]
  • An Zhu, Zonghui Ji, Jingwei Zhao, Wenjing Zhang, Yuqing Sun, Tao Zhang, Shan Gao, Guojun Li, Qi Wang. Effect of Euphorbia factor L1 on intestinal barrier impairment and defecation dysfunction in Caenorhabditis elegans. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Dec; 65(?):153102. doi: 10.1016/j.phymed.2019.153102. [PMID: 31654989]
  • An Zhu, Yuqing Sun, Qianwen Zhong, Jinlan Yang, Tao Zhang, Jingwei Zhao, Qi Wang. Effect of euphorbia factor L1 on oxidative stress, apoptosis, and autophagy in human gastric epithelial cells. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Nov; 64(?):152929. doi: 10.1016/j.phymed.2019.152929. [PMID: 31454650]
  • Yu-Ning Teng, Yingzi Wang, Pei-Ling Hsu, Guang Xin, Yu Zhang, Susan L Morris-Natschke, Masuo Goto, Kuo-Hsiung Lee. Mechanism of action of cytotoxic compounds from the seeds of Euphorbia lathyris. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2018 Mar; 41(?):62-66. doi: 10.1016/j.phymed.2018.02.001. [PMID: 29519320]
  • Jian-ye Zhang, Yan-jun Mi, Shu-peng Chen, Fang Wang, Yong-ju Liang, Li-sheng Zheng, Cheng-jun Shi, Li-yang Tao, Li-ming Chen, Hu-biao Chen, Li-wu Fu. Euphorbia factor L1 reverses ABCB1-mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtion. Journal of cellular biochemistry. 2011 Apr; 112(4):1076-83. doi: 10.1002/jcb.23021. [PMID: 21308736]
  • C Bicchi, G Appendino, C Cordero, P Rubiolo, D Ortelli, J L Veuthey. HPLC-UV and HPLC-positive-ESI-MS analysis of the diterpenoid fraction from caper spurge (Euphorbia lathyris) seed oil. Phytochemical analysis : PCA. 2001 Jul; 12(4):255-62. doi: 10.1002/pca.592. [PMID: 11705332]