Exact Mass: 498.24309179999995
Exact Mass Matches: 498.24309179999995
Found 1 metabolites which its exact mass value is equals to given mass value 498.24309179999995,
within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error
4.0E-5 dalton.
Mutant IDH1-IN-1
Mutant IDH1-IN-1
C30H31FN4O2 (498.24309179999995)
Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.