Exact Mass: 498.24309179999995
Exact Mass Matches: 498.24309179999995
Found 1 metabolites which its exact mass value is equals to given mass value 498.24309179999995,
within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error
8.0E-6 dalton.
Mutant IDH1-IN-1
Mutant IDH1-IN-1
C30H31FN4O2 (498.24309179999995)
Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.