Exact Mass: 498.2366

Exact Mass Matches: 498.2366

Found 119 metabolites which its exact mass value is equals to given mass value 498.2366, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Moexipril

[3S-[2[R*(R*)],3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid, monohydrochloride;[3S-[2[R*(R*)],3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid, monohydrochloride

C27H34N2O7 (498.2366)

Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents

2-[2-[(1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid

2-{2-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

C27H34N2O7 (498.2366)

D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents

beta-Alanine, N-(N-(2-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)-2-oxo-1-(phenylmethyl)ethyl)-L-phenylalanyl)-

3-{[2-({1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]-1-oxo-3-phenylpropan-2-yl}amino)-1-hydroxy-3-phenylpropylidene]amino}propanoate

C27H34N2O7 (498.2366)

Sograzepide

N-[1-(3,3-Dimethyl-2-oxobutyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-n-[3-(methylamino)phenyl]carbamimidate

C28H30N6O3 (498.2379)

Avapritinib

(1S)-1-(4-fluorophenyl)-1-(2-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl}pyrimidin-5-yl)ethan-1-amine

C26H27FN10 (498.2404)

9-Hydroxy-gamma-geraniol-1-O-(4,6-diacetyl-3-angelyl)-beta-D-glucopyranoside|9-Hydroxy-gamma-geraniol-1-O-<4,6-diacetyl-3-angelyl>-beta-D-glucopyranoside

C25H38O10 (498.2465)

Phe Trp Phe

C29H30N4O4 (498.2267)

Trp Phe Phe

C29H30N4O4 (498.2267)

Phe Phe Trp

C29H30N4O4 (498.2267)

Glu His Ile Thr

(4S)-4-amino-4-{[(1S)-1-{[(1S,2S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Glu His Leu Thr

(4S)-4-amino-4-{[(1S)-1-{[(1S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Glu His Thr Ile

(2S,3S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-4-carboxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-3-hydroxybutanamido]-3-methylpentanoic acid

C21H34N6O8 (498.2438)

Glu His Thr Leu

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-4-carboxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-3-hydroxybutanamido]-4-methylpentanoic acid

C21H34N6O8 (498.2438)

Glu Ile His Thr

(4S)-4-amino-4-{[(1S,2S)-1-{[(1S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Glu Ile Thr His

(4S)-4-amino-4-{[(1S,2S)-1-{[(1S,2R)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Glu Leu His Thr

(4S)-4-amino-4-{[(1S)-1-{[(1S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-3-methylbutyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Glu Leu Thr His

(4S)-4-amino-4-{[(1S)-1-{[(1S,2R)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Glu Thr His Ile

(2S,3S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-4-carboxybutanamido]-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-3-methylpentanoic acid

C21H34N6O8 (498.2438)

Glu Thr His Leu

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-4-carboxybutanamido]-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanoic acid

C21H34N6O8 (498.2438)

Glu Thr Ile His

(4S)-4-amino-4-{[(1S,2R)-1-{[(1S,2S)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-hydroxypropyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Glu Thr Leu His

(4S)-4-amino-4-{[(1S,2R)-1-{[(1S)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-hydroxypropyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

His Glu Ile Thr

(4S)-4-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-{[(1S,2S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

His Glu Leu Thr

(4S)-4-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-{[(1S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

His Glu Thr Ile

(2S,3S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-carboxybutanamido]-3-hydroxybutanamido]-3-methylpentanoic acid

C21H34N6O8 (498.2438)

His Glu Thr Leu

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-carboxybutanamido]-3-hydroxybutanamido]-4-methylpentanoic acid

C21H34N6O8 (498.2438)

His Ile Glu Thr

(4S)-4-[(2S,3S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-methylpentanamido]-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

His Ile Thr Glu

(2S)-2-[(2S,3R)-2-[(2S,3S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-methylpentanamido]-3-hydroxybutanamido]pentanedioic acid

C21H34N6O8 (498.2438)

His Leu Glu Thr

(4S)-4-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanamido]-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

His Leu Thr Glu

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanamido]-3-hydroxybutanamido]pentanedioic acid

C21H34N6O8 (498.2438)

His Thr Glu Ile

(2S,3S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-hydroxybutanamido]-4-carboxybutanamido]-3-methylpentanoic acid

C21H34N6O8 (498.2438)

His Thr Glu Leu

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-hydroxybutanamido]-4-carboxybutanamido]-4-methylpentanoic acid

C21H34N6O8 (498.2438)

His Thr Ile Glu

(2S)-2-[(2S,3S)-2-[(2S,3R)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-hydroxybutanamido]-3-methylpentanamido]pentanedioic acid

C21H34N6O8 (498.2438)

His Thr Leu Glu

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-hydroxybutanamido]-4-methylpentanamido]pentanedioic acid

C21H34N6O8 (498.2438)

Ile Glu His Thr

(4S)-4-[(2S,3S)-2-amino-3-methylpentanamido]-4-{[(1S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Ile Glu Thr His

(4S)-4-[(2S,3S)-2-amino-3-methylpentanamido]-4-{[(1S,2R)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Ile His Glu Thr

(4S)-4-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Ile His Thr Glu

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-hydroxybutanamido]pentanedioic acid

C21H34N6O8 (498.2438)

Ile Thr Glu His

(4S)-4-[(2S,3R)-2-[(2S,3S)-2-amino-3-methylpentanamido]-3-hydroxybutanamido]-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Ile Thr His Glu

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S,3S)-2-amino-3-methylpentanamido]-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido]pentanedioic acid

C21H34N6O8 (498.2438)

Leu Glu His Thr

(4S)-4-[(2S)-2-amino-4-methylpentanamido]-4-{[(1S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Leu Glu Thr His

(4S)-4-[(2S)-2-amino-4-methylpentanamido]-4-{[(1S,2R)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Leu His Glu Thr

(4S)-4-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Leu His Thr Glu

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-hydroxybutanamido]pentanedioic acid

C21H34N6O8 (498.2438)

Leu Thr Glu His

(4S)-4-[(2S,3R)-2-[(2S)-2-amino-4-methylpentanamido]-3-hydroxybutanamido]-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Leu Thr His Glu

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-4-methylpentanamido]-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido]pentanedioic acid

C21H34N6O8 (498.2438)

Thr Glu His Ile

(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carboxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-3-methylpentanoic acid

C21H34N6O8 (498.2438)

Thr Glu His Leu

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carboxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanoic acid

C21H34N6O8 (498.2438)

Thr Glu Ile His

(4S)-4-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-{[(1S,2S)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Thr Glu Leu His

(4S)-4-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-{[(1S)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-3-methylbutyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Thr His Glu Ile

(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-4-carboxybutanamido]-3-methylpentanoic acid

C21H34N6O8 (498.2438)

Thr His Glu Leu

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-4-carboxybutanamido]-4-methylpentanoic acid

C21H34N6O8 (498.2438)

Thr His Ile Glu

(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-3-methylpentanamido]pentanedioic acid

C21H34N6O8 (498.2438)

Thr His Leu Glu

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanamido]pentanedioic acid

C21H34N6O8 (498.2438)

Thr Ile Glu His

(4S)-4-[(2S,3S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-methylpentanamido]-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Thr Ile His Glu

(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]pentanedioic acid

C21H34N6O8 (498.2438)

Thr Leu Glu His

(4S)-4-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-methylpentanamido]-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C21H34N6O8 (498.2438)

Thr Leu His Glu

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]pentanedioic acid

C21H34N6O8 (498.2438)

2-O-(beta-D-galactopyranosyl-(1->6)-beta-D-galactopyranosyl) 2S-hydroxynonanoic acid

C21H38O13 (498.2312)

Sograzepide

C28H30N6O3 (498.2379)

C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent C308 - Immunotherapeutic Agent > C63817 - Chemokine Receptor Antagonist Sograzepide?(Netazepide; YF 476; YM-220) is an extremely?potent?, highly?selective?and orally active Gastrin/CCK-B antagonist with an IC50 value of 0.1 nM, has inhibitory effect on Gastrin/CCK-A activity with an IC50 of 502 nM[1]. Sograzepide?(Netazepide; YF 476; YM-220) replaces the specific binding of [125I]CCK-8 to the rat brain, cloned canine and cloned human?Gastrin/CCK-B receptors, with Ki values of 0.068, 0.62 and 0.19 nM, respectively[2].

Avapritinib

C26H27FN10 (498.2404)

C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C164037 - PDGFR-targeting Agent C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C163999 - cKIT-targeting Agent C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C159198 - c-KIT Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor

Gdc-0152

C25H34N6O3S (498.2413)

C274 - Antineoplastic Agent > C129839 - Apoptotic Pathway-targeting Antineoplastic Agent

CCK-B Receptor Antagonist 1

C28H30N6O3 (498.2379)

(Rac)-Sograzepide is an antagonist of cholecystokinin B (CCK-B) receptor, and has the potential of reducing the secretion of gastric acid.

12-(3,4-Dimethoxy-phenyl)-10-(2-morpholin-4-yl-ethyl)-10,12-dihydro-7-oxa-8,10-diaza-benzo[a]anthra cen-11-ylideneamine

C29H30N4O4 (498.2267)

(2R,6Z)-2-Benzyl-1-(cyclopropanecarbonyl)-4-[(4-fluorophenyl)methyl]-5-(4-methoxyphenyl)-5,8-dihydro-2H-1,4-diazocin-3-one

C31H31FN2O3 (498.2319)

4-hydroxy-1-(2-methylpropyl)-2-oxo-N-[4-oxo-2-(phenylmethyl)-3-quinazolinyl]-5,6,7,8-tetrahydroquinoline-3-carboxamide

C29H30N4O4 (498.2267)

3-[[1-[1-(2-furanylmethyl)-5-tetrazolyl]propyl-(2-phenylethyl)amino]methyl]-7-methoxy-1H-quinolin-2-one

C28H30N6O3 (498.2379)

3-(4-nitrophenyl)-N-(4-phenylbutyl)-5-(phenylmethyl)-4,6-dihydro-3aH-pyrrolo[3,4-d]isoxazole-6a-carboxamide

C29H30N4O4 (498.2267)

Trp-Phe-Phe

C29H30N4O4 (498.2267)

(2S,3S,3aR,9bR)-1-[cyclopropyl(oxo)methyl]-3-(hydroxymethyl)-6-oxo-7-phenyl-N-(2-pyridin-4-ylethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide

C29H30N4O4 (498.2267)

(2R,3R,3aS,9bS)-1-[cyclopropyl(oxo)methyl]-3-(hydroxymethyl)-6-oxo-7-phenyl-N-(2-pyridin-4-ylethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide

C29H30N4O4 (498.2267)

(1S,9R,10R,11R)-N-(2,3-dihydro-1H-inden-2-yl)-10-(hydroxymethyl)-6-oxo-12-propanoyl-5-pyridin-4-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

C29H30N4O4 (498.2267)

1-[(1R,3R,4aR,9aS)-1-(hydroxymethyl)-3-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-3-(4-fluorophenyl)urea

C26H31FN4O5 (498.2278)

1-[(1R,3S,4aR,9aS)-1-(hydroxymethyl)-3-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-3-(4-fluorophenyl)urea

C26H31FN4O5 (498.2278)

1-[(1R,3R,4aS,9aR)-1-(hydroxymethyl)-3-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-3-(4-fluorophenyl)urea

C26H31FN4O5 (498.2278)

1-[(1S,3R,4aR,9aS)-1-(hydroxymethyl)-3-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-3-(4-fluorophenyl)urea

C26H31FN4O5 (498.2278)

(1R,9S,10S,11S)-N-(2,3-dihydro-1H-inden-2-yl)-10-(hydroxymethyl)-6-oxo-12-propanoyl-5-pyridin-4-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

C29H30N4O4 (498.2267)

1-[(1S,3S,4aS,9aR)-1-(hydroxymethyl)-3-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-3-(4-fluorophenyl)urea

C26H31FN4O5 (498.2278)

1-[(1S,3R,4aS,9aR)-1-(hydroxymethyl)-3-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-3-(4-fluorophenyl)urea

C26H31FN4O5 (498.2278)

1-[(1S,3S,4aR,9aS)-1-(hydroxymethyl)-3-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-3-(4-fluorophenyl)urea

C26H31FN4O5 (498.2278)

1-[(1R,3S,4aS,9aR)-1-(hydroxymethyl)-3-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-3-(4-fluorophenyl)urea

C26H31FN4O5 (498.2278)

(1R,9S,10S,11S)-10-(hydroxymethyl)-6-oxo-5-[(E)-2-phenylethenyl]-N-propyl-12-(pyridine-4-carbonyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

C29H30N4O4 (498.2267)

(1S,9R,10R,11R)-10-(hydroxymethyl)-6-oxo-5-[(E)-2-phenylethenyl]-N-propyl-12-(pyridine-4-carbonyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

C29H30N4O4 (498.2267)

Phe-Trp-Phe

C29H30N4O4 (498.2267)

Phe-Phe-Trp

C29H30N4O4 (498.2267)

(1-butanoyloxy-3-phosphonooxypropan-2-yl) (3Z,6Z,9Z,12Z,15Z)-octadeca-3,6,9,12,15-pentaenoate

C25H39O8P (498.2382)

(1-acetyloxy-3-phosphonooxypropan-2-yl) (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate

C25H39O8P (498.2382)

Moexipril

C27H34N2O7 (498.2366)

C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents

MGGA 16:4

C25H38O10 (498.2465)

LPA 22:6;O

C25H39O8P (498.2382)

PA 18:4/4:1

C25H39O8P (498.2382)

PA 2:0_20:5

C25H39O8P (498.2382)

PA 20:5/2:0

C25H39O8P (498.2382)

PA 22:5

C25H39O8P (498.2382)

PEth 20:5

C25H39O8P (498.2382)

PM 21:5

C25H39O8P (498.2382)

ST 19:1;O4;GlcA

C25H38O10 (498.2465)

ST 19:2;O5;Hex

C25H38O10 (498.2465)

ST 25:3;O5;S

C25H38O8S (498.2287)

ST 29:7;O2;S

C29H38O5S (498.244)

Mutant IDH1-IN-1

C30H31FN4O2 (498.2431)

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.

3-(acetyloxy)-4,10,11,15,17-pentahydroxy-5,5,10,15-tetramethyl-7-oxapentacyclo[12.2.1.0¹,¹¹.0⁴,⁹.0⁶,⁸]heptadecan-2-yl propanoate

C25H38O10 (498.2465)

(2r)-3-[(2r,3s,4r)-2-[(s)-(1s)-cyclohex-2-en-1-yl(hydroxy)methyl]-4-hexyl-3,5-dihydroxy-3-methyl-4h-pyrrole-2-carbonylsulfanyl]-2-[(1-hydroxyethylidene)amino]propanoic acid

C24H38N2O7S (498.24)

16-acetyl-1-methoxy-12-methyl-23-(2-methylbut-3-en-2-yl)-3,11,14,16-tetraazahexacyclo[12.10.0.0²,¹¹.0⁴,⁹.0¹⁵,²³.0¹⁷,²²]tetracosa-2,4,6,8,17,19,21-heptaene-10,13-dione

C29H30N4O4 (498.2267)

3-(acetyloxy)-2-[(acetyloxy)methyl]-5-hydroxy-6-[(8-hydroxy-7-methyl-3-methylideneoct-6-en-1-yl)oxy]oxan-4-yl 2-methylbut-2-enoate

C25H38O10 (498.2465)

(1s,4s,12r,14s,17s,25r)-25-(2-methylbut-3-en-2-yl)-2,15-dioxo-3,5,16,18-tetraazaheptacyclo[14.10.0.0³,¹⁴.0⁴,¹².0⁶,¹¹.0¹⁷,²⁵.0¹⁹,²⁴]hexacosa-6,8,10,19,21,23-hexaen-12-yl acetate

(1s,4s,12r,14s,17s,25r)-25-(2-methylbut-3-en-2-yl)-2,15-dioxo-3,5,16,18-tetraazaheptacyclo[14.10.0.0³,¹⁴.0⁴,¹².0⁶,¹¹.0¹⁷,²⁵.0¹⁹,²⁴]hexacosa-6,8,10,19,21,23-hexaen-12-yl acetate

C29H30N4O4 (498.2267)

(1s,4ar,6s,7r,7as)-4a,6-dihydroxy-1-[(3-methylbutanoyl)oxy]-1,5,6,7a-tetrahydrospiro[cyclopenta[c]pyran-7,2'-oxiran]-4-ylmethyl 3-methyl-2-[(3-methylbutanoyl)oxy]butanoate

C25H38O10 (498.2465)

4a,6-dihydroxy-1-[(3-methylbutanoyl)oxy]-1,5,6,7a-tetrahydrospiro[cyclopenta[c]pyran-7,2'-oxiran]-4-ylmethyl 3-methyl-2-[(3-methylbutanoyl)oxy]butanoate

C25H38O10 (498.2465)

3-(acetyloxy)-2,4,10,11,15-pentahydroxy-5,5,10,15-tetramethyl-7-oxapentacyclo[12.2.1.0¹,¹¹.0⁴,⁹.0⁶,⁸]heptadecan-17-yl propanoate

C25H38O10 (498.2465)

(1s,4ar,6s,7r,7as)-4a,6-dihydroxy-1-[(3-methylbutanoyl)oxy]-1,5,6,7a-tetrahydrospiro[cyclopenta[c]pyran-7,2'-oxiran]-4-ylmethyl (2r)-3-methyl-2-[(3-methylbutanoyl)oxy]butanoate

C25H38O10 (498.2465)

25-(2-methylbut-3-en-2-yl)-2,15-dioxo-3,5,16,18-tetraazaheptacyclo[14.10.0.0³,¹⁴.0⁴,¹².0⁶,¹¹.0¹⁷,²⁵.0¹⁹,²⁴]hexacosa-6,8,10,19,21,23-hexaen-12-yl acetate

C29H30N4O4 (498.2267)

(1r,2s,3r,4r,6r,8s,9r,10s,11s,14r,15r,17r)-3-(acetyloxy)-4,10,11,15,17-pentahydroxy-5,5,10,15-tetramethyl-7-oxapentacyclo[12.2.1.0¹,¹¹.0⁴,⁹.0⁶,⁸]heptadecan-2-yl propanoate

C25H38O10 (498.2465)

(1s,2s,3r,4r,6r,8s,9r,10s,11s,14r,15r,17r)-3-(acetyloxy)-2,4,10,11,15-pentahydroxy-5,5,10,15-tetramethyl-7-oxapentacyclo[12.2.1.0¹,¹¹.0⁴,⁹.0⁶,⁸]heptadecan-17-yl propanoate

C25H38O10 (498.2465)

(1s,4as,6s,7r,7as)-4a,6-dihydroxy-1-[(3-methylbutanoyl)oxy]-1,5,6,7a-tetrahydrospiro[cyclopenta[c]pyran-7,2'-oxiran]-4-ylmethyl 3-methyl-2-[(3-methylbutanoyl)oxy]butanoate

C25H38O10 (498.2465)

(2r,3r,4r,5r,6r)-3-(acetyloxy)-2-[(acetyloxy)methyl]-5-hydroxy-6-{[(6z)-8-hydroxy-7-methyl-3-methylideneoct-6-en-1-yl]oxy}oxan-4-yl (2z)-2-methylbut-2-enoate

C25H38O10 (498.2465)

(1s,12s,15r,23s)-16-acetyl-1-methoxy-12-methyl-23-(2-methylbut-3-en-2-yl)-3,11,14,16-tetraazahexacyclo[12.10.0.0²,¹¹.0⁴,⁹.0¹⁵,²³.0¹⁷,²²]tetracosa-2,4,6,8,17,19,21-heptaene-10,13-dione

(1s,12s,15r,23s)-16-acetyl-1-methoxy-12-methyl-23-(2-methylbut-3-en-2-yl)-3,11,14,16-tetraazahexacyclo[12.10.0.0²,¹¹.0⁴,⁹.0¹⁵,²³.0¹⁷,²²]tetracosa-2,4,6,8,17,19,21-heptaene-10,13-dione

C29H30N4O4 (498.2267)