Exact Mass: 493.2502476
Exact Mass Matches: 493.2502476
Found 286 metabolites which its exact mass value is equals to given mass value 493.2502476
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Epo A
C26H39NO6S (493.24979540000004)
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.
Imatinib
Imatinib is a drug used to treat certain types of cancer. It is currently marketed by Novartis as Gleevec (USA) or Glivec (Europe/Australia) as its mesylate salt, imatinib mesilate (INN). It is occasionally referred to as CGP57148B or STI571 (especially in older publications). It is used in treating chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies. It is the first member of a new class of agents that act by inhibiting particular tyrosine kinase enzymes, instead of non-specifically inhibiting rapidly dividing cells. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors > L01EA - Bcr-abl tyrosine kinase inhibitors C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor COVID info from Guide to PHARMACOLOGY, clinicaltrial, clinicaltrials, clinical trial, clinical trials C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C164037 - PDGFR-targeting Agent C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C163999 - cKIT-targeting Agent C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C159198 - c-KIT Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C155700 - BCR-ABL Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D000970 - Antineoplastic Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Epothilone A
C26H39NO6S (493.24979540000004)
Imatinib
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors > L01EA - Bcr-abl tyrosine kinase inhibitors C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor COVID info from Guide to PHARMACOLOGY, clinicaltrial, clinicaltrials, clinical trial, clinical trials C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C164037 - PDGFR-targeting Agent C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C163999 - cKIT-targeting Agent C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C159198 - c-KIT Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C155700 - BCR-ABL Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D000970 - Antineoplastic Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS CONFIDENCE standard compound; INTERNAL_ID 2742 INTERNAL_ID 2742; CONFIDENCE standard compound CONFIDENCE standard compound; INTERNAL_ID 8521 CONFIDENCE standard compound; EAWAG_UCHEM_ID 3633
C28H35N3O5_(1R,5R,7S,12R)-12-Hydroxy-4,4,4,4,12,14-hexamethyl-4H,13H-spiro[9,14-diazatetracyclo[5.5.2.0~1,9~.0~3,7~]tetradecane-5,8-[1,4]dioxepino[2,3-g]indole]-9,13(10H)-dione
C28H35N3O5 (493.25765800000005)
Ala Glu Phe Lys
C23H35N5O7 (493.25363600000003)
Ala Glu Lys Phe
C23H35N5O7 (493.25363600000003)
Ala Phe Glu Lys
C23H35N5O7 (493.25363600000003)
Ala Phe Lys Glu
C23H35N5O7 (493.25363600000003)
Ala Ile Gln Tyr
C23H35N5O7 (493.25363600000003)
Ala Ile Tyr Gln
C23H35N5O7 (493.25363600000003)
Ala Lys Glu Phe
C23H35N5O7 (493.25363600000003)
Ala Lys Phe Glu
C23H35N5O7 (493.25363600000003)
Ala Leu Gln Tyr
C23H35N5O7 (493.25363600000003)
Ala Leu Tyr Gln
C23H35N5O7 (493.25363600000003)
Ala Gln Ile Tyr
C23H35N5O7 (493.25363600000003)
Ala Gln Leu Tyr
C23H35N5O7 (493.25363600000003)
Ala Gln Tyr Ile
C23H35N5O7 (493.25363600000003)
Ala Gln Tyr Leu
C23H35N5O7 (493.25363600000003)
Ala Tyr Ile Gln
C23H35N5O7 (493.25363600000003)
Ala Tyr Leu Gln
C23H35N5O7 (493.25363600000003)
Ala Tyr Gln Ile
C23H35N5O7 (493.25363600000003)
Ala Tyr Gln Leu
C23H35N5O7 (493.25363600000003)
Glu Ala Phe Lys
C23H35N5O7 (493.25363600000003)
Glu Ala Lys Phe
C23H35N5O7 (493.25363600000003)
Glu Phe Ala Lys
C23H35N5O7 (493.25363600000003)
Glu Phe Lys Ala
C23H35N5O7 (493.25363600000003)
Glu Lys Ala Phe
C23H35N5O7 (493.25363600000003)
Glu Lys Phe Ala
C23H35N5O7 (493.25363600000003)
Phe Ala Glu Lys
C23H35N5O7 (493.25363600000003)
Phe Ala Lys Glu
C23H35N5O7 (493.25363600000003)
Phe Glu Ala Lys
C23H35N5O7 (493.25363600000003)
Phe Glu Lys Ala
C23H35N5O7 (493.25363600000003)
Phe Ile Asn Thr
C23H35N5O7 (493.25363600000003)
Phe Ile Gln Ser
C23H35N5O7 (493.25363600000003)
Phe Ile Ser Gln
C23H35N5O7 (493.25363600000003)
Phe Ile Thr Asn
C23H35N5O7 (493.25363600000003)
Phe Lys Ala Glu
C23H35N5O7 (493.25363600000003)
Phe Lys Glu Ala
C23H35N5O7 (493.25363600000003)
Phe Leu Asn Thr
C23H35N5O7 (493.25363600000003)
Phe Leu Gln Ser
C23H35N5O7 (493.25363600000003)
Phe Leu Ser Gln
C23H35N5O7 (493.25363600000003)
Phe Leu Thr Asn
C23H35N5O7 (493.25363600000003)
Phe Asn Ile Thr
C23H35N5O7 (493.25363600000003)
Phe Asn Leu Thr
C23H35N5O7 (493.25363600000003)
Phe Asn Thr Ile
C23H35N5O7 (493.25363600000003)
Phe Asn Thr Leu
C23H35N5O7 (493.25363600000003)
Phe Gln Ile Ser
C23H35N5O7 (493.25363600000003)
Phe Gln Leu Ser
C23H35N5O7 (493.25363600000003)
Phe Gln Ser Ile
C23H35N5O7 (493.25363600000003)
Phe Gln Ser Leu
C23H35N5O7 (493.25363600000003)
Phe Gln Thr Val
C23H35N5O7 (493.25363600000003)
Phe Gln Val Thr
C23H35N5O7 (493.25363600000003)
Phe Ser Ile Gln
C23H35N5O7 (493.25363600000003)
Phe Ser Leu Gln
C23H35N5O7 (493.25363600000003)
Phe Ser Gln Ile
C23H35N5O7 (493.25363600000003)
Phe Ser Gln Leu
C23H35N5O7 (493.25363600000003)
Phe Thr Ile Asn
C23H35N5O7 (493.25363600000003)
Phe Thr Leu Asn
C23H35N5O7 (493.25363600000003)
Phe Thr Asn Ile
C23H35N5O7 (493.25363600000003)
Phe Thr Asn Leu
C23H35N5O7 (493.25363600000003)
Phe Thr Gln Val
C23H35N5O7 (493.25363600000003)
Phe Thr Val Gln
C23H35N5O7 (493.25363600000003)
Phe Val Gln Thr
C23H35N5O7 (493.25363600000003)
Phe Val Thr Gln
C23H35N5O7 (493.25363600000003)
Ile Ala Gln Tyr
C23H35N5O7 (493.25363600000003)
Ile Ala Tyr Gln
C23H35N5O7 (493.25363600000003)
Ile Phe Asn Thr
C23H35N5O7 (493.25363600000003)
Ile Phe Gln Ser
C23H35N5O7 (493.25363600000003)
Ile Phe Ser Gln
C23H35N5O7 (493.25363600000003)
Ile Phe Thr Asn
C23H35N5O7 (493.25363600000003)
Ile Asn Phe Thr
C23H35N5O7 (493.25363600000003)
Ile Asn Thr Phe
C23H35N5O7 (493.25363600000003)
Ile Gln Ala Tyr
C23H35N5O7 (493.25363600000003)
Ile Gln Phe Ser
C23H35N5O7 (493.25363600000003)
Ile Gln Ser Phe
C23H35N5O7 (493.25363600000003)
Ile Gln Tyr Ala
C23H35N5O7 (493.25363600000003)
Ile Ser Phe Gln
C23H35N5O7 (493.25363600000003)
Ile Ser Gln Phe
C23H35N5O7 (493.25363600000003)
Ile Thr Phe Asn
C23H35N5O7 (493.25363600000003)
Ile Thr Asn Phe
C23H35N5O7 (493.25363600000003)
Ile Tyr Ala Gln
C23H35N5O7 (493.25363600000003)
Ile Tyr Gln Ala
C23H35N5O7 (493.25363600000003)
Lys Ala Glu Phe
C23H35N5O7 (493.25363600000003)
Lys Ala Phe Glu
C23H35N5O7 (493.25363600000003)
Lys Glu Ala Phe
C23H35N5O7 (493.25363600000003)
Lys Glu Phe Ala
C23H35N5O7 (493.25363600000003)
Lys Phe Ala Glu
C23H35N5O7 (493.25363600000003)
Lys Phe Glu Ala
C23H35N5O7 (493.25363600000003)
Lys Pro Ser Tyr
C23H35N5O7 (493.25363600000003)
Lys Pro Tyr Ser
C23H35N5O7 (493.25363600000003)
Lys Ser Pro Tyr
C23H35N5O7 (493.25363600000003)
Lys Ser Tyr Pro
C23H35N5O7 (493.25363600000003)
Lys Tyr Pro Ser
C23H35N5O7 (493.25363600000003)
Lys Tyr Ser Pro
C23H35N5O7 (493.25363600000003)
Leu Ala Gln Tyr
C23H35N5O7 (493.25363600000003)
Leu Ala Tyr Gln
C23H35N5O7 (493.25363600000003)
Leu Phe Asn Thr
C23H35N5O7 (493.25363600000003)
Leu Phe Gln Ser
C23H35N5O7 (493.25363600000003)
Leu Phe Ser Gln
C23H35N5O7 (493.25363600000003)
Leu Phe Thr Asn
C23H35N5O7 (493.25363600000003)
Leu Asn Phe Thr
C23H35N5O7 (493.25363600000003)
Leu Asn Thr Phe
C23H35N5O7 (493.25363600000003)
Leu Gln Ala Tyr
C23H35N5O7 (493.25363600000003)
Leu Gln Phe Ser
C23H35N5O7 (493.25363600000003)
Leu Gln Ser Phe
C23H35N5O7 (493.25363600000003)
Leu Gln Tyr Ala
C23H35N5O7 (493.25363600000003)
Leu Ser Phe Gln
C23H35N5O7 (493.25363600000003)
Leu Ser Gln Phe
C23H35N5O7 (493.25363600000003)
Leu Thr Phe Asn
C23H35N5O7 (493.25363600000003)
Leu Thr Asn Phe
C23H35N5O7 (493.25363600000003)
Leu Tyr Ala Gln
C23H35N5O7 (493.25363600000003)
Leu Tyr Gln Ala
C23H35N5O7 (493.25363600000003)
Asn Phe Ile Thr
C23H35N5O7 (493.25363600000003)
Asn Phe Leu Thr
C23H35N5O7 (493.25363600000003)
Asn Phe Thr Ile
C23H35N5O7 (493.25363600000003)
Asn Phe Thr Leu
C23H35N5O7 (493.25363600000003)
Asn Ile Phe Thr
C23H35N5O7 (493.25363600000003)
Asn Ile Thr Phe
C23H35N5O7 (493.25363600000003)
Asn Leu Phe Thr
C23H35N5O7 (493.25363600000003)
Asn Leu Thr Phe
C23H35N5O7 (493.25363600000003)
Asn Thr Phe Ile
C23H35N5O7 (493.25363600000003)
Asn Thr Phe Leu
C23H35N5O7 (493.25363600000003)
Asn Thr Ile Phe
C23H35N5O7 (493.25363600000003)
Asn Thr Leu Phe
C23H35N5O7 (493.25363600000003)
Asn Val Val Tyr
C23H35N5O7 (493.25363600000003)
Asn Val Tyr Val
C23H35N5O7 (493.25363600000003)
Asn Tyr Val Val
C23H35N5O7 (493.25363600000003)
Pro Lys Ser Tyr
C23H35N5O7 (493.25363600000003)
Pro Lys Tyr Ser
C23H35N5O7 (493.25363600000003)
Pro Ser Lys Tyr
C23H35N5O7 (493.25363600000003)
Pro Ser Tyr Lys
C23H35N5O7 (493.25363600000003)
Pro Tyr Lys Ser
C23H35N5O7 (493.25363600000003)
Pro Tyr Ser Lys
C23H35N5O7 (493.25363600000003)
Gln Ala Ile Tyr
C23H35N5O7 (493.25363600000003)
Gln Ala Leu Tyr
C23H35N5O7 (493.25363600000003)
Gln Ala Tyr Ile
C23H35N5O7 (493.25363600000003)
Gln Ala Tyr Leu
C23H35N5O7 (493.25363600000003)
Gln Phe Ile Ser
C23H35N5O7 (493.25363600000003)
Gln Phe Leu Ser
C23H35N5O7 (493.25363600000003)
Gln Phe Ser Ile
C23H35N5O7 (493.25363600000003)
Gln Phe Ser Leu
C23H35N5O7 (493.25363600000003)
Gln Phe Thr Val
C23H35N5O7 (493.25363600000003)
Gln Phe Val Thr
C23H35N5O7 (493.25363600000003)
Gln Ile Ala Tyr
C23H35N5O7 (493.25363600000003)
Gln Ile Phe Ser
C23H35N5O7 (493.25363600000003)
Gln Ile Ser Phe
C23H35N5O7 (493.25363600000003)
Gln Ile Tyr Ala
C23H35N5O7 (493.25363600000003)
Gln Leu Ala Tyr
C23H35N5O7 (493.25363600000003)
Gln Leu Phe Ser
C23H35N5O7 (493.25363600000003)
Gln Leu Ser Phe
C23H35N5O7 (493.25363600000003)
Gln Leu Tyr Ala
C23H35N5O7 (493.25363600000003)
Gln Ser Phe Ile
C23H35N5O7 (493.25363600000003)
Gln Ser Phe Leu
C23H35N5O7 (493.25363600000003)
Gln Ser Ile Phe
C23H35N5O7 (493.25363600000003)
Gln Ser Leu Phe
C23H35N5O7 (493.25363600000003)
Gln Thr Phe Val
C23H35N5O7 (493.25363600000003)
Gln Thr Val Phe
C23H35N5O7 (493.25363600000003)
Gln Val Phe Thr
C23H35N5O7 (493.25363600000003)
Gln Val Thr Phe
C23H35N5O7 (493.25363600000003)
Gln Tyr Ala Ile
C23H35N5O7 (493.25363600000003)
Gln Tyr Ala Leu
C23H35N5O7 (493.25363600000003)
Gln Tyr Ile Ala
C23H35N5O7 (493.25363600000003)
Gln Tyr Leu Ala
C23H35N5O7 (493.25363600000003)
Ser Phe Ile Gln
C23H35N5O7 (493.25363600000003)
Ser Phe Leu Gln
C23H35N5O7 (493.25363600000003)
Ser Phe Gln Ile
C23H35N5O7 (493.25363600000003)
Ser Phe Gln Leu
C23H35N5O7 (493.25363600000003)
Ser Ile Phe Gln
C23H35N5O7 (493.25363600000003)
Ser Ile Gln Phe
C23H35N5O7 (493.25363600000003)
Ser Lys Pro Tyr
C23H35N5O7 (493.25363600000003)
Ser Lys Tyr Pro
C23H35N5O7 (493.25363600000003)
Ser Leu Phe Gln
C23H35N5O7 (493.25363600000003)
Ser Leu Gln Phe
C23H35N5O7 (493.25363600000003)
Ser Pro Lys Tyr
C23H35N5O7 (493.25363600000003)
Ser Pro Tyr Lys
C23H35N5O7 (493.25363600000003)
Ser Gln Phe Ile
C23H35N5O7 (493.25363600000003)
Ser Gln Phe Leu
C23H35N5O7 (493.25363600000003)
Ser Gln Ile Phe
C23H35N5O7 (493.25363600000003)
Ser Gln Leu Phe
C23H35N5O7 (493.25363600000003)
Ser Tyr Lys Pro
C23H35N5O7 (493.25363600000003)
Ser Tyr Pro Lys
C23H35N5O7 (493.25363600000003)
Thr Phe Ile Asn
C23H35N5O7 (493.25363600000003)
Thr Phe Leu Asn
C23H35N5O7 (493.25363600000003)
Thr Phe Asn Ile
C23H35N5O7 (493.25363600000003)
Thr Phe Asn Leu
C23H35N5O7 (493.25363600000003)
Thr Phe Gln Val
C23H35N5O7 (493.25363600000003)
Thr Phe Val Gln
C23H35N5O7 (493.25363600000003)
Thr Ile Phe Asn
C23H35N5O7 (493.25363600000003)
Thr Ile Asn Phe
C23H35N5O7 (493.25363600000003)
Thr Leu Phe Asn
C23H35N5O7 (493.25363600000003)
Thr Leu Asn Phe
C23H35N5O7 (493.25363600000003)
Thr Asn Phe Ile
C23H35N5O7 (493.25363600000003)
Thr Asn Phe Leu
C23H35N5O7 (493.25363600000003)
Thr Asn Ile Phe
C23H35N5O7 (493.25363600000003)
Thr Asn Leu Phe
C23H35N5O7 (493.25363600000003)
Thr Gln Phe Val
C23H35N5O7 (493.25363600000003)
Thr Gln Val Phe
C23H35N5O7 (493.25363600000003)
Thr Val Phe Gln
C23H35N5O7 (493.25363600000003)
Thr Val Gln Phe
C23H35N5O7 (493.25363600000003)
Val Phe Gln Thr
C23H35N5O7 (493.25363600000003)
Val Phe Thr Gln
C23H35N5O7 (493.25363600000003)
Val Asn Val Tyr
C23H35N5O7 (493.25363600000003)
Val Asn Tyr Val
C23H35N5O7 (493.25363600000003)
Val Gln Phe Thr
C23H35N5O7 (493.25363600000003)
Val Gln Thr Phe
C23H35N5O7 (493.25363600000003)
Val Thr Phe Gln
C23H35N5O7 (493.25363600000003)
Val Thr Gln Phe
C23H35N5O7 (493.25363600000003)
Val Val Asn Tyr
C23H35N5O7 (493.25363600000003)
Val Val Tyr Asn
C23H35N5O7 (493.25363600000003)
Val Tyr Asn Val
C23H35N5O7 (493.25363600000003)
Val Tyr Val Asn
C23H35N5O7 (493.25363600000003)
Tyr Ala Ile Gln
C23H35N5O7 (493.25363600000003)
Tyr Ala Leu Gln
C23H35N5O7 (493.25363600000003)
Tyr Ala Gln Ile
C23H35N5O7 (493.25363600000003)
Tyr Ala Gln Leu
C23H35N5O7 (493.25363600000003)
Tyr Ile Ala Gln
C23H35N5O7 (493.25363600000003)
Tyr Ile Gln Ala
C23H35N5O7 (493.25363600000003)
Tyr Lys Pro Ser
C23H35N5O7 (493.25363600000003)
Tyr Lys Ser Pro
C23H35N5O7 (493.25363600000003)
Tyr Leu Ala Gln
C23H35N5O7 (493.25363600000003)
Tyr Leu Gln Ala
C23H35N5O7 (493.25363600000003)
Tyr Asn Val Val
C23H35N5O7 (493.25363600000003)
Tyr Pro Lys Ser
C23H35N5O7 (493.25363600000003)
Tyr Pro Ser Lys
C23H35N5O7 (493.25363600000003)
Tyr Gln Ala Ile
C23H35N5O7 (493.25363600000003)
Tyr Gln Ala Leu
C23H35N5O7 (493.25363600000003)
Tyr Gln Ile Ala
C23H35N5O7 (493.25363600000003)
Tyr Gln Leu Ala
C23H35N5O7 (493.25363600000003)
Tyr Ser Lys Pro
C23H35N5O7 (493.25363600000003)
Tyr Ser Pro Lys
C23H35N5O7 (493.25363600000003)
Tyr Val Asn Val
C23H35N5O7 (493.25363600000003)
Tyr Val Val Asn
C23H35N5O7 (493.25363600000003)
6-chloro-2-[4-(4,4-difluoropiperidin-1-yl)butylamino]-N-(2-pyrrolidin-1-ylethyl)quinoline-4-carboxamide
7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
C26H39NO6S (493.24979540000004)
[(1S)-2-[(4-chlorophenyl)methyl]-1-(cyclopropylmethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]methanol
C29H36ClN3O2 (493.24959060000003)
[(1R)-2-[(4-chlorophenyl)methyl]-1-(cyclopropylmethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]methanol
C29H36ClN3O2 (493.24959060000003)
(2S,3S)-10-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2S,3S)-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2R,3R)-8-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2R,3R)-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
N-[(5R,6R,9S)-8-[cyclopropyl(oxo)methyl]-5-methoxy-3,6,9-trimethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C28H35N3O5 (493.25765800000005)
N-[(5R,6S,9R)-8-[cyclopropyl(oxo)methyl]-5-methoxy-3,6,9-trimethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C28H35N3O5 (493.25765800000005)
methyl N-[[(10S,11R)-13-[(2R)-1-hydroxypropan-2-yl]-11,16-dimethyl-14-oxo-9-oxa-13,16-diazatetracyclo[13.7.0.02,7.017,22]docosa-1(15),2,4,6,17,19,21-heptaen-10-yl]methyl]-N-methylcarbamate
C28H35N3O5 (493.25765800000005)
1-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-oxo-2-[4-(phenylmethyl)-1-piperidinyl]ethyl]-3,6-dihydro-2H-pyran-3-yl]-3-(2-methoxyphenyl)urea
C28H35N3O5 (493.25765800000005)
1-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-oxo-2-[4-(phenylmethyl)-1-piperidinyl]ethyl]-3,6-dihydro-2H-pyran-3-yl]-3-(2-methoxyphenyl)urea
C28H35N3O5 (493.25765800000005)
methyl N-[[(10S,11S)-13-[(2R)-1-hydroxypropan-2-yl]-11,16-dimethyl-14-oxo-9-oxa-13,16-diazatetracyclo[13.7.0.02,7.017,22]docosa-1(15),2,4,6,17,19,21-heptaen-10-yl]methyl]-N-methylcarbamate
C28H35N3O5 (493.25765800000005)
(2S,3S)-8-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2R,3R)-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2S,3R)-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2R,3S)-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
N-[(5R,6R,9R)-8-[cyclopropyl(oxo)methyl]-5-methoxy-3,6,9-trimethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C28H35N3O5 (493.25765800000005)
N-[(5S,6S,9S)-8-[cyclopropyl(oxo)methyl]-5-methoxy-3,6,9-trimethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C28H35N3O5 (493.25765800000005)
N-[(5S,6S,9R)-8-[cyclopropyl(oxo)methyl]-5-methoxy-3,6,9-trimethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C28H35N3O5 (493.25765800000005)
N-[(5S,6R,9S)-8-[cyclopropyl(oxo)methyl]-5-methoxy-3,6,9-trimethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C28H35N3O5 (493.25765800000005)
methyl N-[[(10R,11R)-13-[(2R)-1-hydroxypropan-2-yl]-11,16-dimethyl-14-oxo-9-oxa-13,16-diazatetracyclo[13.7.0.02,7.017,22]docosa-1(15),2,4,6,17,19,21-heptaen-10-yl]methyl]-N-methylcarbamate
C28H35N3O5 (493.25765800000005)
methyl N-[[(10R,11S)-13-[(2S)-1-hydroxypropan-2-yl]-11,16-dimethyl-14-oxo-9-oxa-13,16-diazatetracyclo[13.7.0.02,7.017,22]docosa-1(15),2,4,6,17,19,21-heptaen-10-yl]methyl]-N-methylcarbamate
C28H35N3O5 (493.25765800000005)
methyl N-[[(10S,11R)-13-[(2S)-1-hydroxypropan-2-yl]-11,16-dimethyl-14-oxo-9-oxa-13,16-diazatetracyclo[13.7.0.02,7.017,22]docosa-1(15),2,4,6,17,19,21-heptaen-10-yl]methyl]-N-methylcarbamate
C28H35N3O5 (493.25765800000005)
1-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-oxo-2-[4-(phenylmethyl)-1-piperidinyl]ethyl]-3,6-dihydro-2H-pyran-3-yl]-3-(2-methoxyphenyl)urea
C28H35N3O5 (493.25765800000005)
1-[(2S,3S,6R)-2-(hydroxymethyl)-6-[2-oxo-2-[4-(phenylmethyl)-1-piperidinyl]ethyl]-3,6-dihydro-2H-pyran-3-yl]-3-(2-methoxyphenyl)urea
C28H35N3O5 (493.25765800000005)
1-[(2R,3R,6S)-2-(hydroxymethyl)-6-[2-oxo-2-[4-(phenylmethyl)-1-piperidinyl]ethyl]-3,6-dihydro-2H-pyran-3-yl]-3-(2-methoxyphenyl)urea
C28H35N3O5 (493.25765800000005)
1-[(2S,3S,6S)-2-(hydroxymethyl)-6-[2-oxo-2-[4-(phenylmethyl)-1-piperidinyl]ethyl]-3,6-dihydro-2H-pyran-3-yl]-3-(2-methoxyphenyl)urea
C28H35N3O5 (493.25765800000005)
methyl N-[[(10R,11R)-13-[(2S)-1-hydroxypropan-2-yl]-11,16-dimethyl-14-oxo-9-oxa-13,16-diazatetracyclo[13.7.0.02,7.017,22]docosa-1(15),2,4,6,17,19,21-heptaen-10-yl]methyl]-N-methylcarbamate
C28H35N3O5 (493.25765800000005)
methyl N-[[(10S,11S)-13-[(2S)-1-hydroxypropan-2-yl]-11,16-dimethyl-14-oxo-9-oxa-13,16-diazatetracyclo[13.7.0.02,7.017,22]docosa-1(15),2,4,6,17,19,21-heptaen-10-yl]methyl]-N-methylcarbamate
C28H35N3O5 (493.25765800000005)
(1S,6R,7R,8R)-6-Hydroxy-4,4,6,10,10,13-hexamethylspiro[10H-[1,4]dioxepino[2,3-g]indole-8,11-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-9,14-dione
C28H35N3O5 (493.25765800000005)
2-amino-3-[[3-[(9Z,12Z)-hexadeca-9,12-dienoyl]oxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxypropanoic acid
C22H40NO9P (493.24405600000006)
Epothilone A
C26H39NO6S (493.24979540000004)
An epithilone that is epothilone C in which the double bond in the macrocyclic lactone ring has been oxidised to the corresponding epoxide (the 13R,14S diastereoisomer). C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.
(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-5,7,9,9-tetramethyl-14-[1-(2-methyl-4-thiazolyl)prop-1-en-2-yl]-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione
C26H39NO6S (493.24979540000004)
(4s,7r,8s,9s,13z,15s,16r)-4,8,15-trihydroxy-5,5,7,9-tetramethyl-16-[(1e)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione
C26H39NO6S (493.24979540000004)
(1'r,3'r,7's,8r,12'r)-9,12'-dihydroxy-4,4,4',4',12',14'-hexamethyl-9',14'-diazaspiro[[1,4]dioxepino[2,3-g]indole-8,5'-tetracyclo[5.5.2.0¹,⁹.0³,⁷]tetradecan]-13'-one
C28H35N3O5 (493.25765800000005)
(4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-16-[(1e)-3-hydroxy-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-5,5,7,9-tetramethyl-1-oxacyclohexadec-13-ene-2,6-dione
C26H39NO6S (493.24979540000004)