Exact Mass: 474.1971
Exact Mass Matches: 474.1971
Found 222 metabolites which its exact mass value is equals to given mass value 474.1971
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Sildenafil
Sildenafil is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH), developed by the pharmaceutical company Pfizer. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a form of ischaemic cardiovascular disease). Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections; Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. The molecular structure of sildenafil is similar to that of cGMP and acts as a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and better erections. Without sexual stimulation, and therefore lack of activation of the NO/cGMP system, sildenafil should not cause an erection. Other drugs that operate by the same mechanism include tadalafil (Cialis) and vardenafil (Levitra); Sildenafil citrate, sold under the names Viagra, Revatio and generically under various other names, is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH), developed by the pharmaceutical company Pfizer. Viagra pills are blue and diamond-shaped with the words Pfizer on one side, and VGR xx (where xx stands for 25, 50 or 100, the dose of that pill in milligrams) on the other. Its primary competitors on the market are tadalafil (Cialis), and vardenafil (Levitra). Sildenafil is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH), developed by the pharmaceutical company Pfizer. G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals > G04BE - Drugs used in erectile dysfunction D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058986 - Phosphodiesterase 5 Inhibitors C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor > C2127 - cGMP Phosphodiesterase Inhibitor COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent D000089162 - Genitourinary Agents > D064804 - Urological Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Quinapril hydrochloride
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
N-[2-(Diacetylamino)-3-(4-isothiocyanatophenyl)propyl]-N-[2-(diacetylamino)propyl]acetamide
2-((2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-[1,1'-biphenyl]-3-yl)oxy)acetic acid
BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells[1][2][3].
Ibrutinib metabolite M37
MeOSuc-AAPA-CMK
Mitopodozidum
N-(2-Benzyl-3-((2-amino-4-methylpentyl)dithio)-1-oxopropyl)glycine benzyl ester
5alpha,6beta,8alpha-Trihydroxy-28-norisotoonafolin
[(4R,6aR,9S,9aR,9bR)-9-methyl-3,6-dimethylidene-2,8-dioxo-3a,4,5,6a,7,9,9a,9b-octahydroazuleno[4,5-b]furan-4-yl] (E)-4-hydroxy-2-[[(E)-4-hydroxy-2-methylbut-2-enoyl]oxymethyl]but-2-enoate
(+)-(7S,8R,8R)-4,4,9-trihydroxy-3,5-dimethoxy-9-(5-hydroxy-4-oxo-pentanoyl)-2,7-cyclolignane|clemomanshurinane B
ligustrin-<4-hydroxy-5-(4,5-dihydroxytigloyloxy)-tiglate>|ligustrin-[4-hydroxy-5-(4,5-dihydroxytigloyloxy)-tiglate]
(+)-(7S,8R,8R)-4,4,9-trihydroxy-3,5-dimethoxy-9-(5-hydroxy-4-oxo-pentanoyl)-2,7-cyclolignane|clemomanshurinane A
NSC 72274; Podophyllic acid ethylhydrazide; Podophyllinic acid 2-ethylhydrazide
8beta-5-(4,5-dihydroxytigloyl)-4-hydroxytigloyloxydesacetylzuubergenin|8beta-5-<4,5-dihydroxytigloyl>-4-hydroxytigloyloxydesacetylzuubergenin
ligustrin-4-hydroxy-5-(2-1,2-dihydroxyacryloyl)-tiglate
10-beta-D-glucopyranosyloxy-3,9-dimethoxy-7-methoxymethyl-5H-dibenzo[a,c][7]annulene|subavenoside E
lobarin
A member of the class of 2-benzofurans that is 3-butyl-3-hydroxy-2-benzofuran-1(3H)-one substituted by a 3-carboxy-4,6-dihydroxy-2-pentylphenoxy group and a methoxy group at positions 4 and 6, respectively. It is a metabolite isolated from the Sumatran lichen, Stereocaulon halei.
desacetoxyzuubergenin-8beta-4-hydroxy-5-(1,2-dihydroxyethylacryloyl)-tiglate
3alpha,4alpha-epoxyligustrin-4-hydroxy-5-(4-hydroxytigloyl)-tiglate
(aS,5S,6S,7S)-5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-5-[Ac]oxybenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol|schisanwilsonin F
C25H30O9_(4R,6aR,9S,9aR,9bR)-9-Methyl-3,6-bis(methylene)-2,8-dioxododecahydroazuleno[4,5-b]furan-4-yl (2E)-4-hydroxy-2-({[(2E)-4-hydroxy-2-methyl-2-butenoyl]oxy}methyl)-2-butenoate
sildenafil
G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals > G04BE - Drugs used in erectile dysfunction D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058986 - Phosphodiesterase 5 Inhibitors C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor > C2127 - cGMP Phosphodiesterase Inhibitor COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent D000089162 - Genitourinary Agents > D064804 - Urological Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Cys Pro Gln Gln
Cys Gln Pro Gln
Cys Gln Gln Pro
Glu Glu Pro Thr
Glu Glu Thr Pro
Glu Pro Glu Thr
Glu Pro Thr Glu
Glu Thr Glu Pro
Glu Thr Pro Glu
His Met Ser Thr
His Met Thr Ser
His Ser Met Thr
His Ser Thr Met
His Thr Met Ser
His Thr Ser Met
Met His Ser Thr
Met His Thr Ser
Met Met Pro Pro
Met Asn Asn Pro
Met Asn Pro Asn
Met Pro Met Pro
Met Pro Asn Asn
Met Pro Pro Met
Met Ser His Thr
Met Ser Thr His
Met Thr His Ser
Met Thr Ser His
Asn Met Asn Pro
Asn Met Pro Asn
Asn Asn Met Pro
Asn Asn Pro Met
Asn Pro Met Asn
Asn Pro Asn Met
Pro Cys Gln Gln
Pro Glu Glu Thr
Pro Glu Thr Glu
Pro Met Met Pro
Pro Met Asn Asn
Pro Met Pro Met
Pro Asn Met Asn
Pro Asn Asn Met
Pro Pro Met Met
Pro Gln Cys Gln
Pro Gln Gln Cys
Pro Thr Glu Glu
Gln Cys Pro Gln
Gln Cys Gln Pro
Gln Pro Cys Gln
Gln Pro Gln Cys
Gln Gln Cys Pro
Gln Gln Pro Cys
Ser His Met Thr
Ser His Thr Met
Ser Met His Thr
Ser Met Thr His
Ser Thr His Met
Ser Thr Met His
Thr Glu Glu Pro
Thr Glu Pro Glu
Thr His Met Ser
Thr His Ser Met
Thr Met His Ser
Thr Met Ser His
Thr Pro Glu Glu
Thr Ser His Met
Thr Ser Met His
(4R,6aR,9S,9aR,9bR)-9-Methyl-3,6-bis(methylene)-2,8-dioxododecahydroazuleno[4,5-b]furan-4-yl (2E)-4-hydroxy-2-({[(2E)-4-hydroxy-2-methyl-2-butenoyl]oxy}methyl)-2-butenoate
ETHYL 4-(2,4-BIS(BENZYLOXY)-5-ISOPROPYLPHENYL)-2-HYDROXY-4-OXOBUT-2-ENOATE
butyl prop-2-enoate,2-methylprop-2-enoic acid,2-methyl-2-(prop-2-enoylamino)propane-1-sulfonic acid,prop-2-enenitrile
N-[2-(4-{[4-(Cyclobutylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino}-11-azatricyclo[6.2.1.02,7]undeca-2,4,6-trien-11-yl)-2-oxoethyl]acetamide
MITOPODOZIDE
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C1931 - Antineoplastic Plant Product > C1331 - Epipodophyllotoxin Compound C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C1748 - Topoisomerase Inhibitor D000970 - Antineoplastic Agents C1907 - Drug, Natural Product
pf-03814735
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C61074 - Serine/Threonine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
ZD 7155 hydrochloride
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
methyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazole-[3,4-c]pyridine-3-carboxylate
Ananolignan D
A lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura ananosma.
Ananolignan E
A lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura ananosma.
MSACK
D009676 - Noxae > D000477 - Alkylating Agents > D000590 - Amino Acid Chloromethyl Ketones