Exact Mass: 473.19843160000005
Exact Mass Matches: 473.19843160000005
Found 500 metabolites which its exact mass value is equals to given mass value 473.19843160000005
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
(6R)-Folinic acid
The active metabolite of folic acid. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. [HMDB] D020011 - Protective Agents > D000931 - Antidotes C2140 - Adjuvant > C2078 - Folic Acid Derivative Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1]. Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1].
Raloxifene
C28H27NO4S (473.1660702000001)
Raloxifene is only found in individuals that have used or taken this drug. It is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue. [PubChem]. Raloxifene binds to estrogen receptors, resulting in differential expression of multiple estrogen-regulated genes in different tissues. Raloxifene produces estrogen-like effects on bone, reducing resorption of bone and increasing bone mineral density in postmenopausal women, thus slowing the rate of bone loss. The maintenance of bone mass by raloxifene and estrogens is, in part, through the regulation of the gene-encoding transforming growth factor-β3 (TGF-β3), which is a bone matrix protein with antiosteoclastic properties. Raloxifene activates TGF-β3 through pathways that are estrogen receptor-mediated but involve DNA sequences distinct from the estrogen response element. The drug also binds to the estrogen receptor and acts as an estrogen agonist in preosteoclastic cells, which results in the inhibtion of their proliferative capacity. This inhibition is thought to contribute to the drugs effect on bone resorption. Other mechanisms include the suppression of activity of the bone-resorbing cytokine interleukin-6 promoter activity. Raloxifene also antagonizes the effects of estrogen on mammary tissue and blocks uterotrophic responses to estrogen. By competing with estrogens for the estrogen receptors in reproductive tissue, raloxifene prevents the transcriptional activation of genes containing the estrogen response element. As well, raloxifene inhibits the estradiol-dependent proliferation of MCF-7 human mammary tumor cells in vitro. The mechansim of action of raloxifene has not been fully determined, but evidence suggests that the drugs tissue-specific estrogen agonist or antagonist activity is related to the structural differences between the raloxifene-estrogen receptor complex (specifically the surface topography of AF-2) and the estrogen-estrogen receptor complex. Also, the existence of at least 2 estrogen receptors (ERα, ERβ) may contribute to the tissue specificity of raloxifene. CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3671; ORIGINAL_PRECURSOR_SCAN_NO 3667 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7479; ORIGINAL_PRECURSOR_SCAN_NO 7477 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3606; ORIGINAL_PRECURSOR_SCAN_NO 3604 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3605; ORIGINAL_PRECURSOR_SCAN_NO 3603 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7456; ORIGINAL_PRECURSOR_SCAN_NO 7455 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7507; ORIGINAL_PRECURSOR_SCAN_NO 7505 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7491; ORIGINAL_PRECURSOR_SCAN_NO 7487 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7503; ORIGINAL_PRECURSOR_SCAN_NO 7502 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7515; ORIGINAL_PRECURSOR_SCAN_NO 7513 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3597; ORIGINAL_PRECURSOR_SCAN_NO 3594 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3612; ORIGINAL_PRECURSOR_SCAN_NO 3610 CONFIDENCE standard compound; INTERNAL_ID 236; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3602; ORIGINAL_PRECURSOR_SCAN_NO 3597 G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03X - Other sex hormones and modulators of the genital system > G03XC - Selective estrogen receptor modulators D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D020847 - Estrogen Receptor Modulators D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1821 - Selective Estrogen Receptor Modulator C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist CONFIDENCE standard compound; INTERNAL_ID 2754 CONFIDENCE standard compound; INTERNAL_ID 8536 D050071 - Bone Density Conservation Agents C1892 - Chemopreventive Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[1].
10-Formyltetrahydrofolate
10-formyltetrahydrofolate, also known as 10-formyl-thf or 10-formyltetrahydropteroylglutamic acid, is a member of the class of compounds known as tetrahydrofolic acids. Tetrahydrofolic acids are heterocyclic compounds based on the 5,6,7,8-tetrahydropteroic acid skeleton conjugated with at least one L-glutamic acid unit. 10-formyltetrahydrofolate is practically insoluble (in water) and a moderately acidic compound (based on its pKa). 10-formyltetrahydrofolate can be found in a number of food items such as agave, black salsify, white cabbage, and lemon, which makes 10-formyltetrahydrofolate a potential biomarker for the consumption of these food products. 10-formyltetrahydrofolate exists in all eukaryotes, ranging from yeast to humans. In humans, 10-formyltetrahydrofolate is involved in several metabolic pathways, some of which include mercaptopurine action pathway, methionine metabolism, purine metabolism, and folate malabsorption, hereditary. 10-formyltetrahydrofolate is also involved in several metabolic disorders, some of which include myoadenylate deaminase deficiency, adenine phosphoribosyltransferase deficiency (APRT), molybdenum cofactor deficiency, and cystathionine beta-synthase deficiency. 10-Formyltetrahydrofolate (10-CHO-THF) is a form of tetrahydrofolate that acts as a donor of formyl groups in anabolism. In these reactions 10-CHO-THF is used as a substrate in formyltransferase reactions. This is important in purine biosynthesis, where 10-CHO-THF is a substrate for phosphoribosylaminoimidazolecarboxamide formyltransferase, as well as in the formylation of the methionyl initiator tRNA (fMet-tRNA), when 10-CHO-THF is a substrate for methionyl-tRNA formyltransferase . 10-Formyltetrahydrofolate (10-CHO-THF) is form of tetrahydrofolate that acts as a donor of formyl groups in anabolism. In particular, 10-CHO-THF is used as a substrate in a number of formyltransferase reactions. It plays an important role in purine biosynthesis, where 10-CHO-THF is a substrate for phosphoribosylaminoimidazolecarboxamide formyltransferase, as well as in the formylation of the methionyl initiator tRNA (fMet-tRNA), when 10-CHO-THF is a substrate for methionyl-tRNA formyltransferase. 10-Formyltetrahydrofolate is a substrate for Trifunctional purine biosynthetic protein adenosine-3, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase (mitochondrial), 10-formyltetrahydrofolate dehydrogenase, Folylpolyglutamate synthase (mitochondrial), Bifunctional purine biosynthesis protein PURH and C-1-tetrahydrofolate synthase (cytoplasmic).
OA-6129B1
Temsavir
C24H23N7O4 (473.18114380000003)
C254 - Anti-Infective Agent > C281 - Antiviral Agent > C1660 - Anti-HIV Agent
OA-6129 B2
Folinic acid
(6S)-5-formyltetrahydrofolic acid is the pharmacologically active (6S)-stereoisomer of 5-formyltetrahydrofolic acid. It has a role as an antineoplastic agent and a metabolite. It is a conjugate acid of a (6S)-5-formyltetrahydrofolate(2-). Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be rapidly converted to the biologically available methyl-tetrahydrofolate form while the dextro form is slowly excreted by the kidneys. Despite this difference in activity, the two commercially available forms have been shown to be pharmacokinetically identical and may be used interchangeably with limited differences in efficacy or side effects (Kovoor et al, 2009). As folate analogs, levoleucovorin and leucovorin are both used to counteract the toxic effects of folic acid antagonists, such as methotrexate, which act by inhibiting the enzyme dihydrofolate reductase (DHFR). They are indicated for use as rescue therapy following use of high-dose methotrexate in the treatment of osteosarcoma or for diminishing the toxicity associated with inadvertent overdosage of folic acid antagonists. Levoleucovorin, as the product Fusilev (FDA), has an additional indication for use in combination chemotherapy with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal cancer. Folic acid is an essential B vitamin required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA or protein. However, in order to function in this role, it must first be reduced by the enzyme dihydrofolate reductase (DHFR) into the cofactors dihydrofolate (DHF) and tetrahydrofolate (THF). This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is disrupted when high-dose methotrexate is used for cancer therapy. As methotrexate functions as a DHFR inhibitor to prevent DNA synthesis in rapidly dividing cells, it also prevents the formation of DHF and THF. This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible for numerous adverse side effects of methotrexate therapy. As levoleucovorin and leucovorin are analogs of tetrahydrofolate (THF), they are able to bypass DHFR reduction and act as a cellular replacement for the co-factor THF, thereby preventing these toxic side effects. Levoleucovorin is a Folate Analog. Levoleucovorin is a natural product found in Homo sapiens with data available. Levoleucovorin is the active l-isomer of the racemic mixture of the 5-formyl derivative of tetrahydrofolic acid. Metabolically active, l-leucovorin, also known levoleucovorin, does not require bioactivation by dihydrofolate reductase, an enzyme inhibited by folic acid antagonists. This agent may enhance the effects of fluoropyrimidines by stabilizing their binding to the enzyme thymidylate synthase. (NCI04) 5-Formyltetrahydrofolic acid is a metabolite found in or produced by Saccharomyces cerevisiae. A folate analog consisting of the pharmacologically active isomer of LEUCOVORIN. See also: Levoleucovorin Calcium (active moiety of); Levoleucovorin disodium (active moiety of). Folinic acid (CAS: 58-05-9), also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate (a chemotherapy agent and immune system suppressant) and pyrimethamine (Wikipedia). Folinic acid is the active metabolite of folic acid. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. D020011 - Protective Agents > D000931 - Antidotes C2140 - Adjuvant > C2078 - Folic Acid Derivative Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1]. Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1].
Pteroyl-D-glutamic acid
The active metabolite of Folic acid, is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. Folic acid, a water-soluble B-complex vitamin, is found in foods such as liver, kidneys, yeast, and leafy, green vegetables. Folic acid is used to diagnose folate deficiency and to treat topical sprue and megaloblastic and macrocytic anemias, hematologic complications resulting from a deficiency in folic acid. A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. The active metabolite of Folic acid, is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid.
CD 1790
C25H27N7O3 (473.21752720000006)
CD 1790 is a metabolite of linagliptin. Linagliptin (BI-1356, trade names Tradjenta and Trajenta) is a DPP-4 inhibitor developed by Boehringer Ingelheim for treatment of type II diabetes. Linagliptin (once-daily) was approved by the US FDA on 2 May 2011 for treatment of type II diabetes. It is being marketed by Boehringer Ingelheim and Lilly. (Wikipedia)
Mefox
Temsavir
C24H23N7O4 (473.18114380000003)
C254 - Anti-Infective Agent > C281 - Antiviral Agent > C1660 - Anti-HIV Agent
Formyltetrahydrofolate
Ketotrexate
C21H27N7O6 (473.20227220000004)
quinoneimine
C23H27N3O8 (473.17980620000003)
2-[[4-[(2-Amino-4-oxo-5,6,7,8-tetrahydro-3H-pteridin-6-yl)methylamino]benzoyl]amino]-4-formylpentanedioic acid
[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[2-(4-hydroxyphenyl)ethoxy]oxan-2-yl]methyl 2-(2-oxo-1,3-dihydroindol-3-yl)acetate
plumbagine G alpha-D-xylopyranoside|plumbagoside D
Folinic acid
Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1]. Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1].
Ala Pro Thr Trp
Ala Pro Trp Thr
Ala Gln Gln Gln
Ala Thr Pro Trp
Ala Thr Trp Pro
Ala Trp Pro Thr
Ala Trp Thr Pro
Cys His Lys Ser
C18H31N7O6S (473.20564260000003)
Cys His Asn Thr
Cys His Gln Ser
Cys His Ser Lys
C18H31N7O6S (473.20564260000003)
Cys His Ser Gln
Cys His Thr Asn
Cys Lys His Ser
C18H31N7O6S (473.20564260000003)
Cys Lys Ser His
C18H31N7O6S (473.20564260000003)
Cys Asn His Thr
Cys Asn Thr His
Cys Gln His Ser
Cys Gln Ser His
Cys Ser His Lys
C18H31N7O6S (473.20564260000003)
Cys Ser His Gln
Cys Ser Lys His
C18H31N7O6S (473.20564260000003)
Cys Ser Gln His
Cys Thr His Asn
Cys Thr Asn His
Asp Asp Lys Pro
C19H31N5O9 (473.21216760000004)
Asp Asp Pro Lys
C19H31N5O9 (473.21216760000004)
Asp Asp Pro Gln
C18H27N5O10 (473.17578419999995)
Asp Asp Gln Pro
C18H27N5O10 (473.17578419999995)
Asp Glu Asn Pro
C18H27N5O10 (473.17578419999995)
Asp Glu Pro Asn
C18H27N5O10 (473.17578419999995)
Asp Gly Pro Trp
C22H27N5O7 (473.19103920000003)
Asp Gly Trp Pro
C22H27N5O7 (473.19103920000003)
Asp Lys Asp Pro
C19H31N5O9 (473.21216760000004)
Asp Lys Pro Asp
C19H31N5O9 (473.21216760000004)
Asp Asn Glu Pro
C18H27N5O10 (473.17578419999995)
Asp Asn Pro Glu
C18H27N5O10 (473.17578419999995)
Asp Pro Asp Lys
C19H31N5O9 (473.21216760000004)
Asp Pro Asp Gln
C18H27N5O10 (473.17578419999995)
Asp Pro Glu Asn
C18H27N5O10 (473.17578419999995)
Asp Pro Gly Trp
C22H27N5O7 (473.19103920000003)
Asp Pro Lys Asp
C19H31N5O9 (473.21216760000004)
Asp Pro Asn Glu
C18H27N5O10 (473.17578419999995)
Asp Pro Gln Asp
C18H27N5O10 (473.17578419999995)
Asp Pro Arg Ser
Asp Pro Ser Arg
Asp Pro Trp Gly
C22H27N5O7 (473.19103920000003)
Asp Gln Asp Pro
C18H27N5O10 (473.17578419999995)
Asp Gln Pro Asp
C18H27N5O10 (473.17578419999995)
Asp Arg Pro Ser
Asp Arg Ser Pro
Asp Ser Pro Arg
Asp Ser Arg Pro
Asp Trp Gly Pro
C22H27N5O7 (473.19103920000003)
Asp Trp Pro Gly
C22H27N5O7 (473.19103920000003)
Glu Asp Asn Pro
C18H27N5O10 (473.17578419999995)
Glu Asp Pro Asn
C18H27N5O10 (473.17578419999995)
Glu Asn Asp Pro
C18H27N5O10 (473.17578419999995)
Glu Asn Pro Asp
C18H27N5O10 (473.17578419999995)
Glu Pro Asp Asn
C18H27N5O10 (473.17578419999995)
Glu Pro Asn Asp
C18H27N5O10 (473.17578419999995)
Glu Pro Gln Thr
C19H31N5O9 (473.21216760000004)
Glu Pro Thr Gln
C19H31N5O9 (473.21216760000004)
Glu Gln Pro Thr
C19H31N5O9 (473.21216760000004)
Glu Gln Thr Pro
C19H31N5O9 (473.21216760000004)
Glu Thr Pro Gln
C19H31N5O9 (473.21216760000004)
Glu Thr Gln Pro
C19H31N5O9 (473.21216760000004)
Phe Gly His Asn
C21H27N7O6 (473.20227220000004)
Phe Gly Asn His
C21H27N7O6 (473.20227220000004)
Phe His Gly Asn
C21H27N7O6 (473.20227220000004)
Phe His Asn Gly
C21H27N7O6 (473.20227220000004)
Phe Asn Gly His
C21H27N7O6 (473.20227220000004)
Phe Asn His Gly
C21H27N7O6 (473.20227220000004)
Phe Asn Pro Pro
Phe Pro Asn Pro
Phe Pro Pro Asn
Gly Asp Pro Trp
C22H27N5O7 (473.19103920000003)
Gly Asp Trp Pro
C22H27N5O7 (473.19103920000003)
Gly Phe His Asn
C21H27N7O6 (473.20227220000004)
Gly Phe Asn His
C21H27N7O6 (473.20227220000004)
Gly His Phe Asn
C21H27N7O6 (473.20227220000004)
Gly His Asn Phe
C21H27N7O6 (473.20227220000004)
Gly Asn Phe His
C21H27N7O6 (473.20227220000004)
Gly Asn His Phe
C21H27N7O6 (473.20227220000004)
Gly Pro Asp Trp
C22H27N5O7 (473.19103920000003)
Gly Pro Trp Asp
C22H27N5O7 (473.19103920000003)
Gly Trp Asp Pro
C22H27N5O7 (473.19103920000003)
Gly Trp Pro Asp
C22H27N5O7 (473.19103920000003)
His Cys Lys Ser
C18H31N7O6S (473.20564260000003)
His Cys Asn Thr
His Cys Gln Ser
His Cys Ser Lys
C18H31N7O6S (473.20564260000003)
His Cys Ser Gln
His Cys Thr Asn
His Phe Gly Asn
C21H27N7O6 (473.20227220000004)
His Phe Asn Gly
C21H27N7O6 (473.20227220000004)
His Gly Phe Asn
C21H27N7O6 (473.20227220000004)
His Gly Asn Phe
C21H27N7O6 (473.20227220000004)
His Lys Cys Ser
C18H31N7O6S (473.20564260000003)
His Lys Ser Cys
C18H31N7O6S (473.20564260000003)
His Asn Cys Thr
His Asn Phe Gly
C21H27N7O6 (473.20227220000004)
His Asn Gly Phe
C21H27N7O6 (473.20227220000004)
His Asn Thr Cys
His Gln Cys Ser
His Gln Ser Cys
His Ser Cys Lys
C18H31N7O6S (473.20564260000003)
His Ser Cys Gln
His Ser Lys Cys
C18H31N7O6S (473.20564260000003)
His Ser Gln Cys
His Thr Cys Asn
His Thr Asn Cys
Ile Met Asn Pro
C20H35N5O6S (473.23079300000006)
Ile Met Pro Asn
C20H35N5O6S (473.23079300000006)
Ile Asn Met Pro
C20H35N5O6S (473.23079300000006)
Ile Asn Asn Asn
Ile Asn Pro Met
C20H35N5O6S (473.23079300000006)
Ile Pro Met Asn
C20H35N5O6S (473.23079300000006)
Ile Pro Asn Met
C20H35N5O6S (473.23079300000006)
Lys Cys His Ser
C18H31N7O6S (473.20564260000003)
Lys Cys Ser His
C18H31N7O6S (473.20564260000003)
Lys Asp Asp Pro
C19H31N5O9 (473.21216760000004)
Lys Asp Pro Asp
C19H31N5O9 (473.21216760000004)
Lys His Cys Ser
C18H31N7O6S (473.20564260000003)
Lys His Ser Cys
C18H31N7O6S (473.20564260000003)
Lys Pro Asp Asp
C19H31N5O9 (473.21216760000004)
Lys Ser Cys His
C18H31N7O6S (473.20564260000003)
Lys Ser His Cys
C18H31N7O6S (473.20564260000003)
Leu Met Asn Pro
C20H35N5O6S (473.23079300000006)
Leu Met Pro Asn
C20H35N5O6S (473.23079300000006)
Leu Asn Met Pro
C20H35N5O6S (473.23079300000006)
Leu Asn Asn Asn
Leu Asn Pro Met
C20H35N5O6S (473.23079300000006)
Leu Pro Met Asn
C20H35N5O6S (473.23079300000006)
Leu Pro Asn Met
C20H35N5O6S (473.23079300000006)
Met Ile Asn Pro
C20H35N5O6S (473.23079300000006)
Met Ile Pro Asn
C20H35N5O6S (473.23079300000006)
Met Leu Asn Pro
C20H35N5O6S (473.23079300000006)
Met Leu Pro Asn
C20H35N5O6S (473.23079300000006)
Met Asn Ile Pro
C20H35N5O6S (473.23079300000006)
Met Asn Leu Pro
C20H35N5O6S (473.23079300000006)
Met Asn Pro Ile
C20H35N5O6S (473.23079300000006)
Met Asn Pro Leu
C20H35N5O6S (473.23079300000006)
Met Pro Ile Asn
C20H35N5O6S (473.23079300000006)
Met Pro Leu Asn
C20H35N5O6S (473.23079300000006)
Met Pro Asn Ile
C20H35N5O6S (473.23079300000006)
Met Pro Asn Leu
C20H35N5O6S (473.23079300000006)
Met Pro Gln Val
C20H35N5O6S (473.23079300000006)
Met Pro Val Gln
C20H35N5O6S (473.23079300000006)
Met Gln Pro Val
C20H35N5O6S (473.23079300000006)
Met Gln Val Pro
C20H35N5O6S (473.23079300000006)
Met Val Pro Gln
C20H35N5O6S (473.23079300000006)
Met Val Gln Pro
C20H35N5O6S (473.23079300000006)
Asn Cys His Thr
Asn Cys Thr His
Asn Asp Glu Pro
C18H27N5O10 (473.17578419999995)
Asn Asp Pro Glu
C18H27N5O10 (473.17578419999995)
Asn Glu Asp Pro
C18H27N5O10 (473.17578419999995)
Asn Glu Pro Asp
C18H27N5O10 (473.17578419999995)
Asn Phe Gly His
C21H27N7O6 (473.20227220000004)
Asn Phe His Gly
C21H27N7O6 (473.20227220000004)
Asn Phe Pro Pro
Asn Gly Phe His
C21H27N7O6 (473.20227220000004)
Asn Gly His Phe
C21H27N7O6 (473.20227220000004)
Asn His Cys Thr
Asn His Phe Gly
C21H27N7O6 (473.20227220000004)
Asn His Gly Phe
C21H27N7O6 (473.20227220000004)
Asn His Thr Cys
Asn Ile Met Pro
C20H35N5O6S (473.23079300000006)
Asn Ile Asn Asn
Asn Ile Pro Met
C20H35N5O6S (473.23079300000006)
Asn Leu Met Pro
C20H35N5O6S (473.23079300000006)
Asn Leu Asn Asn
Asn Leu Pro Met
C20H35N5O6S (473.23079300000006)
Asn Met Ile Pro
C20H35N5O6S (473.23079300000006)
Asn Met Leu Pro
C20H35N5O6S (473.23079300000006)
Asn Met Pro Ile
C20H35N5O6S (473.23079300000006)
Asn Met Pro Leu
C20H35N5O6S (473.23079300000006)
Asn Asn Ile Asn
Asn Asn Leu Asn
Asn Asn Asn Ile
Asn Asn Asn Leu
Asn Asn Gln Val
Asn Asn Val Gln
Asn Pro Asp Glu
C18H27N5O10 (473.17578419999995)
Asn Pro Glu Asp
C18H27N5O10 (473.17578419999995)
Asn Pro Phe Pro
Asn Pro Ile Met
C20H35N5O6S (473.23079300000006)
Asn Pro Leu Met
C20H35N5O6S (473.23079300000006)
Asn Pro Met Ile
C20H35N5O6S (473.23079300000006)
Asn Pro Met Leu
C20H35N5O6S (473.23079300000006)
Asn Pro Pro Phe
Asn Gln Asn Val
Asn Gln Val Asn
Asn Thr Cys His
Asn Thr His Cys
Asn Val Asn Gln
Asn Val Gln Asn
Pro Ala Thr Trp
Pro Ala Trp Thr
Pro Asp Asp Lys
C19H31N5O9 (473.21216760000004)
Pro Asp Asp Gln
C18H27N5O10 (473.17578419999995)
Pro Asp Glu Asn
C18H27N5O10 (473.17578419999995)
Pro Asp Gly Trp
C22H27N5O7 (473.19103920000003)
Pro Asp Lys Asp
C19H31N5O9 (473.21216760000004)
Pro Asp Asn Glu
C18H27N5O10 (473.17578419999995)
Pro Asp Gln Asp
C18H27N5O10 (473.17578419999995)
Pro Asp Arg Ser
Pro Asp Ser Arg
Pro Asp Trp Gly
C22H27N5O7 (473.19103920000003)
Pro Glu Asp Asn
C18H27N5O10 (473.17578419999995)
Pro Glu Asn Asp
C18H27N5O10 (473.17578419999995)
Pro Glu Gln Thr
C19H31N5O9 (473.21216760000004)
Pro Glu Thr Gln
C19H31N5O9 (473.21216760000004)
Pro Phe Asn Pro
Pro Phe Pro Asn
Pro Gly Asp Trp
C22H27N5O7 (473.19103920000003)
Pro Gly Trp Asp
C22H27N5O7 (473.19103920000003)
Pro Ile Met Asn
C20H35N5O6S (473.23079300000006)
Pro Ile Asn Met
C20H35N5O6S (473.23079300000006)
Pro Lys Asp Asp
C19H31N5O9 (473.21216760000004)
Pro Leu Met Asn
C20H35N5O6S (473.23079300000006)
Pro Leu Asn Met
C20H35N5O6S (473.23079300000006)
Pro Met Ile Asn
C20H35N5O6S (473.23079300000006)
Pro Met Leu Asn
C20H35N5O6S (473.23079300000006)
Pro Met Asn Ile
C20H35N5O6S (473.23079300000006)
Pro Met Asn Leu
C20H35N5O6S (473.23079300000006)
Pro Met Gln Val
C20H35N5O6S (473.23079300000006)
Pro Met Val Gln
C20H35N5O6S (473.23079300000006)
Pro Asn Asp Glu
C18H27N5O10 (473.17578419999995)
Pro Asn Glu Asp
C18H27N5O10 (473.17578419999995)
Pro Asn Phe Pro
Pro Asn Ile Met
C20H35N5O6S (473.23079300000006)
Pro Asn Leu Met
C20H35N5O6S (473.23079300000006)
Pro Asn Met Ile
C20H35N5O6S (473.23079300000006)
Pro Asn Met Leu
C20H35N5O6S (473.23079300000006)
Pro Asn Pro Phe
Pro Pro Phe Asn
Pro Pro Asn Phe
Pro Gln Asp Asp
C18H27N5O10 (473.17578419999995)
Pro Gln Glu Thr
C19H31N5O9 (473.21216760000004)
Pro Gln Met Val
C20H35N5O6S (473.23079300000006)
Pro Gln Thr Glu
C19H31N5O9 (473.21216760000004)
Pro Gln Val Met
C20H35N5O6S (473.23079300000006)
Pro Arg Asp Ser
Pro Arg Ser Asp
Pro Ser Asp Arg
Pro Ser Arg Asp
Pro Thr Ala Trp
Pro Thr Glu Gln
C19H31N5O9 (473.21216760000004)
Pro Thr Gln Glu
C19H31N5O9 (473.21216760000004)
Pro Thr Trp Ala
Pro Val Met Gln
C20H35N5O6S (473.23079300000006)
Pro Val Gln Met
C20H35N5O6S (473.23079300000006)
Pro Trp Ala Thr
Pro Trp Asp Gly
C22H27N5O7 (473.19103920000003)
Pro Trp Gly Asp
C22H27N5O7 (473.19103920000003)
Pro Trp Thr Ala
Gln Ala Gln Gln
Gln Cys His Ser
Gln Cys Ser His
Gln Asp Asp Pro
C18H27N5O10 (473.17578419999995)
Gln Asp Pro Asp
C18H27N5O10 (473.17578419999995)
Gln Glu Pro Thr
C19H31N5O9 (473.21216760000004)
Gln Glu Thr Pro
C19H31N5O9 (473.21216760000004)
Gln His Cys Ser
Gln His Ser Cys
Gln Met Pro Val
C20H35N5O6S (473.23079300000006)
Gln Met Val Pro
C20H35N5O6S (473.23079300000006)
Gln Asn Asn Val
Gln Asn Val Asn
Gln Pro Asp Asp
C18H27N5O10 (473.17578419999995)
Gln Pro Glu Thr
C19H31N5O9 (473.21216760000004)
Gln Pro Met Val
C20H35N5O6S (473.23079300000006)
Gln Pro Thr Glu
C19H31N5O9 (473.21216760000004)
Gln Pro Val Met
C20H35N5O6S (473.23079300000006)
Gln Gln Ala Gln
Gln Gln Gln Ala
Gln Ser Cys His
Gln Ser His Cys
Gln Thr Glu Pro
C19H31N5O9 (473.21216760000004)
Gln Thr Pro Glu
C19H31N5O9 (473.21216760000004)
Gln Val Met Pro
C20H35N5O6S (473.23079300000006)
Gln Val Asn Asn
Gln Val Pro Met
C20H35N5O6S (473.23079300000006)
Arg Asp Pro Ser
Arg Asp Ser Pro
Arg Pro Asp Ser
Arg Pro Ser Asp
Arg Ser Asp Pro
Arg Ser Pro Asp
Ser Cys His Lys
C18H31N7O6S (473.20564260000003)
Ser Cys His Gln
Ser Cys Lys His
C18H31N7O6S (473.20564260000003)
Ser Cys Gln His
Ser Asp Pro Arg
Ser Asp Arg Pro
Ser His Cys Lys
C18H31N7O6S (473.20564260000003)
Ser His Cys Gln
Ser His Lys Cys
C18H31N7O6S (473.20564260000003)
Ser His Gln Cys
Ser Lys Cys His
C18H31N7O6S (473.20564260000003)
Ser Lys His Cys
C18H31N7O6S (473.20564260000003)
Ser Pro Asp Arg
Ser Pro Arg Asp
Ser Gln Cys His
Ser Gln His Cys
Ser Arg Asp Pro
Ser Arg Pro Asp
Thr Ala Pro Trp
Thr Ala Trp Pro
Thr Cys His Asn
Thr Cys Asn His
Thr Glu Pro Gln
C19H31N5O9 (473.21216760000004)
Thr Glu Gln Pro
C19H31N5O9 (473.21216760000004)
Thr His Cys Asn
Thr His Asn Cys
Thr Asn Cys His
Thr Asn His Cys
Thr Pro Ala Trp
Thr Pro Glu Gln
C19H31N5O9 (473.21216760000004)
Thr Pro Gln Glu
C19H31N5O9 (473.21216760000004)
Thr Pro Trp Ala
Thr Gln Glu Pro
C19H31N5O9 (473.21216760000004)
Thr Gln Pro Glu
C19H31N5O9 (473.21216760000004)
Thr Trp Ala Pro
Thr Trp Pro Ala
Val Met Pro Gln
C20H35N5O6S (473.23079300000006)
Val Met Gln Pro
C20H35N5O6S (473.23079300000006)
Val Asn Asn Gln
Val Asn Gln Asn
Val Pro Met Gln
C20H35N5O6S (473.23079300000006)
Val Pro Gln Met
C20H35N5O6S (473.23079300000006)
Val Gln Met Pro
C20H35N5O6S (473.23079300000006)
Val Gln Asn Asn
Val Gln Pro Met
C20H35N5O6S (473.23079300000006)
Trp Ala Pro Thr
Trp Ala Thr Pro
Trp Asp Gly Pro
C22H27N5O7 (473.19103920000003)
Trp Asp Pro Gly
C22H27N5O7 (473.19103920000003)
Trp Gly Asp Pro
C22H27N5O7 (473.19103920000003)
Trp Gly Pro Asp
C22H27N5O7 (473.19103920000003)
Trp Pro Ala Thr
Trp Pro Asp Gly
C22H27N5O7 (473.19103920000003)
Trp Pro Gly Asp
C22H27N5O7 (473.19103920000003)
Trp Pro Thr Ala
Trp Thr Ala Pro
Trp Thr Pro Ala
CAY10641
C28H27NO6 (473.18382820000005)
NBD-FTY720 phenoxy
((2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(4-hydroxyphenethoxy)tetrahydro-2H-pyran-2-yl)methyl 2-(2-oxoindolin-3-yl)acetate
(1-NAPHTHYL) 2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE
Thieno[2,3-b]quinoline-2-carboxamide, N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2-methoxyphenyl)-7-methyl- (9CI)
C27H27N3O3S (473.1773032000001)
4-[5-(2-chlorophenyl)-4-[4-(dimethylamino)phenyl]-oxazol-2-yl]-N,N-dipropyl-aniline
1-(4-Methoxyphenyl)-6-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
C26H27N5O4 (473.20629420000006)
1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, 1-(4-ethoxyphenyl)-4,5,6,7-tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-
C26H27N5O4 (473.20629420000006)
Simenepag isopropyl
C26H35NO5S (473.2235820000001)
C78283 - Agent Affecting Organs of Special Senses > C29705 - Anti-glaucoma Agent
Benzyl 2-acetamido-2-deoxy-3-O-beta-D-galactopyranosyl-alpha-D-galactopyranoside
C21H31NO11 (473.18970160000003)
2-imino-10-methyl-N-[2-(4-morpholinyl)ethyl]-5-oxo-1-(3-pyridinylmethyl)-3-dipyrido[3,4-c:1,2-f]pyrimidinecarboxamide
C25H27N7O3 (473.21752720000006)
4-[[6-Hydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclohexa-2,4-dien-1-ylidene]amino]-1,5-dimethyl-2-phenylpyrazol-3-one
C23H27N3O8 (473.17980620000003)
Platensimycin A5 Methyl Ester
A polycyclic cage compound that is the methyl ester derivative of the dihydroxy substituted platensimycin. It is isolated from Streptomyces platensis.
Platencin A11 Methyl Ester
A natural product found in Streptomyces platensis.
6-hydroxy platensimycin A1 methyl ester
A natural product found in Streptomyces platensis.
2-(4-propylphenyl)-N-[2-(4-sulfamoylphenyl)ethyl]-4-quinolinecarboxamide
C27H27N3O3S (473.1773032000001)
4-amino-N5-(4-butoxyphenyl)-N5-[2-(cyclohexylamino)-2-oxoethyl]isothiazole-3,5-dicarboxamide
C23H31N5O4S (473.20966460000005)
3-(benzenesulfonyl)-N-[2-(diethylamino)ethyl]-N-(4,6-dimethyl-1,3-benzothiazol-2-yl)propanamide
C24H31N3O3S2 (473.18067360000003)
4-[2-[(1-acetyl-4-oxo-6-spiro[3,4-dihydro-2H-1-benzopyran-2,4-piperidine]yl)oxy]-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester
Platensimycin A6 Methyl Ester
A natural product found in Streptomyces platensis.
4-[(3aR,4R,9bR)-4-(hydroxymethyl)-5-methyl-1-(4-methylphenyl)sulfonyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-8-yl]benzonitrile
C27H27N3O3S (473.1773032000001)
[(1R)-1-ethylsulfonyl-2-[(2-fluorophenyl)methyl]-7-methoxy-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3-azetidine]yl]methanol
C24H28FN3O4S (473.17844600000006)
N-[(2S,4aR,12aS)-5-methyl-2-[2-(methylamino)-2-oxoethyl]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-3,5-difluorobenzamide
N-[(2R,4aR,12aS)-5-methyl-2-[2-(methylamino)-2-oxoethyl]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-3,5-difluorobenzamide
N-[(2S,4aR,12aR)-5-methyl-2-[2-(methylamino)-2-oxoethyl]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-3,5-difluorobenzamide
N-[(2R,4aR,12aR)-5-methyl-2-[2-(methylamino)-2-oxoethyl]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-3,5-difluorobenzamide
N-[(2S,4aS,12aS)-5-methyl-2-[2-(methylamino)-2-oxoethyl]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-3,5-difluorobenzamide
N-[(2R,4aS,12aS)-5-methyl-2-[2-(methylamino)-2-oxoethyl]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-3,5-difluorobenzamide
N-[[(4S,5S)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-8-[(E)-prop-1-enyl]-4,5-dihydro-3H-6,1lambda6,2-benzoxathiazocin-5-yl]methyl]-N-methylpyridine-4-carboxamide
C24H31N3O5S (473.19843160000005)
N-[[(2S,3S)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-8-[(E)-prop-1-enyl]-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-2-yl]methyl]-N-methylbenzenesulfonamide
C24H31N3O5S (473.19843160000005)
1-[(2R,3S,6R)-6-[2-[(4-chlorophenyl)sulfonylamino]ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-cyclohexylurea
C21H32ClN3O5S (473.17510920000007)
1-[(2R,3R,6R)-6-[2-[(4-chlorophenyl)sulfonylamino]ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-cyclohexylurea
C21H32ClN3O5S (473.17510920000007)
(1S,2aR,8bR)-2-(1,3-benzodioxol-5-ylmethyl)-1-(hydroxymethyl)-N-(2-methoxyphenyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinoline-4-carboxamide
C27H27N3O5 (473.19506120000005)
N-[(2R,4aS,12aR)-5-methyl-2-[2-(methylamino)-2-oxoethyl]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-3,5-difluorobenzamide
4-[(3aS,4S,9bS)-4-(hydroxymethyl)-5-methyl-1-(4-methylphenyl)sulfonyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-8-yl]benzonitrile
C27H27N3O3S (473.1773032000001)
3-[(3aR,4S,9bR)-4-(hydroxymethyl)-5-methyl-1-(2-methylphenyl)sulfonyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-8-yl]benzonitrile
C27H27N3O3S (473.1773032000001)
[(1S)-7-methoxy-1,9-dimethyl-2-[(1-methyl-4-imidazolyl)sulfonyl]-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]methanol
C23H31N5O4S (473.20966460000005)
1-[(2S,3R,6S)-6-[2-[(4-chlorophenyl)sulfonylamino]ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-cyclohexylurea
C21H32ClN3O5S (473.17510920000007)
1-[(2S,3S,6S)-6-[2-[(4-chlorophenyl)sulfonylamino]ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-cyclohexylurea
C21H32ClN3O5S (473.17510920000007)
1-[(2S,3S,6R)-6-[2-[(4-chlorophenyl)sulfonylamino]ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-cyclohexylurea
C21H32ClN3O5S (473.17510920000007)
1-[(2R,3R,6S)-6-[2-[(4-chlorophenyl)sulfonylamino]ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-cyclohexylurea
C21H32ClN3O5S (473.17510920000007)
2-[(2S,5R,6S)-5-[(2-fluorophenyl)sulfonylamino]-6-(hydroxymethyl)-2-oxanyl]-N-[3-(4-morpholinyl)propyl]acetamide
(1R,2aR,8bR)-2-(1,3-benzodioxol-5-ylmethyl)-1-(hydroxymethyl)-N-(2-methoxyphenyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinoline-4-carboxamide
C27H27N3O5 (473.19506120000005)
(1R,2aS,8bS)-2-(1,3-benzodioxol-5-ylmethyl)-1-(hydroxymethyl)-N-(2-methoxyphenyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinoline-4-carboxamide
C27H27N3O5 (473.19506120000005)
N-[(2S,4aS,12aR)-5-methyl-2-[2-(methylamino)-2-oxoethyl]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-3,5-difluorobenzamide
2-[(3R,6aR,8S,10aR)-3-hydroxy-1-[oxo(3-pyridinyl)methyl]-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocin-8-yl]-N-[(4-chlorophenyl)methyl]acetamide
C24H28ClN3O5 (473.17173880000007)
4-[(3aS,4R,9bS)-4-(hydroxymethyl)-5-methyl-1-(4-methylphenyl)sulfonyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-8-yl]benzonitrile
C27H27N3O3S (473.1773032000001)
4-[(3aR,4S,9bR)-4-(hydroxymethyl)-5-methyl-1-(4-methylphenyl)sulfonyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-8-yl]benzonitrile
C27H27N3O3S (473.1773032000001)
3-[(3aS,4R,9bS)-4-(hydroxymethyl)-5-methyl-1-(2-methylphenyl)sulfonyl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinolin-8-yl]benzonitrile
C27H27N3O3S (473.1773032000001)
[(1R)-7-methoxy-1,9-dimethyl-2-[(1-methyl-4-imidazolyl)sulfonyl]-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]methanol
C23H31N5O4S (473.20966460000005)
[(1S)-1-ethylsulfonyl-2-[(2-fluorophenyl)methyl]-7-methoxy-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3-azetidine]yl]methanol
C24H28FN3O4S (473.17844600000006)
5-O-[(S)-hydroxy(octanoyloxy)phosphoryl]adenosine
C18H28N5O8P (473.16754180000004)
2-(2-Carbomethoxyphenylamino)-4-phenyl-6-(4-phenoxyphenyl)pyrimidine
Raloxifene
C28H27NO4S (473.1660702000001)
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03X - Other sex hormones and modulators of the genital system > G03XC - Selective estrogen receptor modulators D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D020847 - Estrogen Receptor Modulators D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1821 - Selective Estrogen Receptor Modulator C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist D050071 - Bone Density Conservation Agents C1892 - Chemopreventive Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[1].
(5R,6S)-3-[2-[3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6R)-3-[2-[3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
beta-D-Gal-(1->3)-alpha-D-GalNAc-OBn
C21H31NO11 (473.18970160000003)
An amino disaccharide consisting of benzyl 2-acetamido-2-deoxy-D-galactoside having a beta-D-galactosyl residue attached at the 3-position.
ALOX15-IN-1
C24H31N3O5S (473.19843160000005)
ALOX15-IN-1 (compound 8b) is a potent inhibitor of the linoleate oxygenase activity of rabbit and human ALOX15 with IC50s of 0.04 and 2.06 μM for ALOX15 0rthologs linoleic acid (LA) and arachidonic acid (AA), respectively[1].
ASN007
ASN007 (ERK-IN-3) is a potent and orally active inhibitor of ERK. ASN007 inhibits ERK1/2 with low single-digit nM IC50 values. ASN007 can be used for the research of cancers driven by RAS mutations[1].
Usmarapride
Usmarapride (SUVN-D4010) is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM). Usmarapride (SUVN-D4010) can be used for the research of cognitive deficits associated with Alzheimer's disease[1].
n-[2,6-dihydroxy-3-(methoxycarbonyl)phenyl]-3-[(1s,5s,10s)-10-hydroxy-10-(hydroxymethyl)-5-methyl-4-oxotricyclo[7.2.1.0¹,⁶]dodec-2-en-5-yl]propanimidic acid
(2r,9s,9ar)-9-hydroxy-9-{[(1s,4s)-3-hydroxy-1-isopropyl-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl]methyl}-2-methyl-1h,2h,9ah-imidazo[1,2-a]indol-3-one
C26H27N5O4 (473.20629420000006)
(2s,9s,9ar)-9-hydroxy-9-{[(1r,4r)-3-hydroxy-1-isopropyl-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl]methyl}-2-methyl-1h,2h,9ah-imidazo[1,2-a]indol-3-one
C26H27N5O4 (473.20629420000006)
(4r,5s,6e)-5-methoxy-4-methyl-7-(2-{2-[(2s,3e,5e)-7-methylocta-3,5-dien-2-yl]-1,3-thiazol-4-yl}-1,3-thiazol-4-yl)-3-oxohept-6-enimidic acid
C24H31N3O3S2 (473.18067360000003)
n-[2,6-dihydroxy-3-(methoxycarbonyl)phenyl]-3-[(1r,2r,5s,7s,9s)-2-hydroxy-5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.1⁷,¹⁰.0¹,⁶]tridecan-5-yl]propanimidic acid
6-[(s)-(acetyloxy)[(5r)-4-methoxy-6-methyl-2h,5h,7h,8h-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]methyl]-2,3-dimethoxybenzoic acid
n-[2,6-dihydroxy-3-(methoxycarbonyl)phenyl]-3-{2-hydroxy-5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.1⁷,¹⁰.0¹,⁶]tridecan-5-yl}propanimidic acid
n-[2,6-dihydroxy-3-(methoxycarbonyl)phenyl]-3-[(1s,5s,6r,8s,9r)-9-hydroxy-9-(hydroxymethyl)-5-methyl-4-oxotricyclo[6.2.2.0¹,⁶]dodec-2-en-5-yl]propanimidic acid
(2s,9r,9ar)-9-hydroxy-9-{[(1s,4r)-3-hydroxy-1-methyl-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl]methyl}-2-isopropyl-1h,2h,9ah-imidazo[1,2-a]indol-3-one
C26H27N5O4 (473.20629420000006)
(2r)-2-[(4r)-1-(2-hydroxy-4-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}butyl)-2-iminoimidazolidin-4-yl]-3-[(2r)-4-methyl-5-oxo-2h-furan-2-yl]propanoic acid
(5r,6s)-3-({2-[(1-hydroxy-3-{[(2r)-1,2,4-trihydroxy-3,3-dimethylbutylidene]amino}propylidene)amino]ethyl}sulfanyl)-6-[(1s)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
5-[4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]-4-hydroxy-17-methyl-12,16,18-trioxapentacyclo[8.7.1.0¹,¹⁰.0³,⁸.0¹¹,¹⁵]octadeca-3,5,7-triene-2,9,13-trione
n-[(2r,3s,4r,6r)-3-hydroxy-6-[(11r,15r,17r)-4-hydroxy-17-methyl-2,9,13-trioxo-12,16-dioxatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadeca-1(10),3(8),4,6-tetraen-5-yl]-2-methyloxan-4-yl]-n-methylmethanamine oxide
(5r,5as,6s,9as,9bs)-6-[(acetyloxy)methyl]-9b-hydroxy-6,9a-dimethyl-3-oxo-1h,5h,5ah,7h,8h,9h-naphtho[1,2-c]furan-5-yl 4-nitrobenzoate
(2s,9s,9ar)-9-hydroxy-9-{[(1s,4r)-3-hydroxy-1-isopropyl-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl]methyl}-2-methyl-1h,2h,9ah-imidazo[1,2-a]indol-3-one
C26H27N5O4 (473.20629420000006)
n-(3-hydroxy-6-{4-hydroxy-17-methyl-2,9,13-trioxo-12,16-dioxatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadeca-1(10),3,5,7-tetraen-7-yl}-2-methyloxan-4-yl)-n-methylmethanamine oxide
n-[2,6-dihydroxy-3-(methoxycarbonyl)phenyl]-3-[9-hydroxy-9-(hydroxymethyl)-5-methyl-4-oxotricyclo[6.2.2.0¹,⁶]dodec-2-en-5-yl]propanimidic acid
n-[(2r,3s,4r,6r)-3-hydroxy-6-[(11r,15r,17r)-4-hydroxy-17-methyl-2,9,13-trioxo-12,16-dioxatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadeca-1(10),3,5,7-tetraen-7-yl]-2-methyloxan-4-yl]-n-methylmethanamine oxide
5-methoxy-4-methyl-7-{2-[2-(7-methylocta-3,5-dien-2-yl)-1,3-thiazol-4-yl]-1,3-thiazol-4-yl}-3-oxohept-6-enimidic acid
C24H31N3O3S2 (473.18067360000003)
n-[2,6-dihydroxy-3-(methoxycarbonyl)phenyl]-3-[10-hydroxy-10-(hydroxymethyl)-5-methyl-4-oxotricyclo[7.2.1.0¹,⁶]dodec-2-en-5-yl]propanimidic acid
(2r,9s,9ar)-9-hydroxy-9-{[(1r,4r)-3-hydroxy-1-isopropyl-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl]methyl}-2-methyl-1h,2h,9ah-imidazo[1,2-a]indol-3-one
C26H27N5O4 (473.20629420000006)
9-hydroxy-9-({3-hydroxy-1-methyl-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl}methyl)-2-isopropyl-1h,2h,9ah-imidazo[1,2-a]indol-3-one
C26H27N5O4 (473.20629420000006)
(12s,16r,18r)-5-[(2r,4r,5s,6r)-4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]-4-hydroxy-18-methyl-10,13,17-trioxatetracyclo[9.7.0.0³,⁸.0¹²,¹⁶]octadeca-1(11),3,5,7-tetraene-2,9,14-trione
9'-({1,3-dihydroxy-1-methyl-6-oxo-4h-pyrazino[2,1-b]quinazolin-4-yl}methyl)-9'-hydroxy-1',9'a-dihydrospiro[cyclopropane-1,2'-imidazo[1,2-a]indol]-3'-one
(11r,15r,17r)-5-[(5s,6r)-4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]-2,9-dihydroxy-17-methyl-12,16-dioxatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadeca-1,3(8),5,9-tetraene-4,7,13-trione
6-[(acetyloxy)methyl]-9b-hydroxy-6,9a-dimethyl-3-oxo-1h,5h,5ah,7h,8h,9h-naphtho[1,2-c]furan-5-yl 4-nitrobenzoate
9-hydroxy-9-({3-hydroxy-1-isopropyl-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl}methyl)-2-methyl-1h,2h,9ah-imidazo[1,2-a]indol-3-one
C26H27N5O4 (473.20629420000006)
(9'r,9'as)-9'-{[(1r,4r)-1,3-dihydroxy-1-methyl-6-oxo-4h-pyrazino[2,1-b]quinazolin-4-yl]methyl}-9'-hydroxy-1',9'a-dihydrospiro[cyclopropane-1,2'-imidazo[1,2-a]indol]-3'-one
(2r,9s,9ar)-9-hydroxy-9-{[(1s,4r)-3-hydroxy-1-isopropyl-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl]methyl}-2-methyl-1h,2h,9ah-imidazo[1,2-a]indol-3-one
C26H27N5O4 (473.20629420000006)