Exact Mass: 467.9736

Exact Mass Matches: 467.9736

Found 43 metabolites which its exact mass value is equals to given mass value 467.9736, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Deoxyuridine triphosphate

({[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid

C9H15N2O14P3 (467.9736)


Dutp, also known as 2-deoxyuridine 5-triphosphate or deoxy-utp, is a member of the class of compounds known as pyrimidine 2-deoxyribonucleoside triphosphates. Pyrimidine 2-deoxyribonucleoside triphosphates are pyrimidine nucleotides with a triphosphate group linked to the ribose moiety lacking a hydroxyl group at position 2. Dutp is slightly soluble (in water) and an extremely strong acidic compound (based on its pKa). Dutp can be found in a number of food items such as bilberry, japanese chestnut, black radish, and lovage, which makes dutp a potential biomarker for the consumption of these food products. Dutp can be found primarily in prostate Tissue, as well as throughout most human tissues. Dutp exists in all living species, ranging from bacteria to humans. In humans, dutp is involved in the pyrimidine metabolism. Dutp is also involved in few metabolic disorders, which include beta ureidopropionase deficiency, dihydropyrimidinase deficiency, MNGIE (mitochondrial neurogastrointestinal encephalopathy), and UMP synthase deficiency (orotic aciduria). Moreover, dutp is found to be associated with prostate cancer. Dutp is a non-carcinogenic (not listed by IARC) potentially toxic compound. Metabolism of organophosphates occurs principally by oxidation, by hydrolysis via esterases and by reaction with glutathione. Demethylation and glucuronidation may also occur. Oxidation of organophosphorus pesticides may result in moderately toxic products. In general, phosphorothioates are not directly toxic but require oxidative metabolism to the proximal toxin. The glutathione transferase reactions produce products that are, in most cases, of low toxicity. Paraoxonase (PON1) is a key enzyme in the metabolism of organophosphates. PON1 can inactivate some organophosphates through hydrolysis. PON1 hydrolyzes the active metabolites in several organophosphates insecticides as well as, nerve agents such as soman, sarin, and VX. The presence of PON1 polymorphisms causes there to be different enzyme levels and catalytic efficiency of this esterase, which in turn suggests that different individuals may be more susceptible to the toxic effect of organophosphate exposure (T3DB). Deoxyuridine triphosphate (dUTP) is a deoxynucleotide triphosphate (dNTP) that is chemically similar to uridine triphosphate (UTP) except that it has a deoxyribose sugar instead of a ribose sugar. DNA synthesis requires the availability of deoxynucleotide triphosphates (dTTP, dATP, dGTP, dCTP), whereas RNA synthesis requires the availability of nucleotide triphosphates (NTPs) such as TTP, ATP, GTP, and UTP. The conversion of nucleotide triphosphates (NTPs) into dNTPs can only be done in the diphosphate form. Typically, an NTP has one phosphate removed to become an NDP. This is then converted into a dNDP by an enzyme called ribonucleotide reductase and followed by the re-addition of phosphate to give a dNTP. dUTP is a substrate for several enzymes, including inosine triphosphate pyrophosphatase, deoxyuridine 5-triphosphate nucleotidohydrolase (mitochondrial), uridine-cytidine kinase 1, nucleoside diphosphate kinase 3, nucleoside diphosphate kinase B, nucleoside diphosphate kinase 6, nucleoside diphosphate kinase (mitochondrial), nucleoside diphosphate kinase homolog 5, nucleoside diphosphate kinase A, and nucleoside diphosphate kinase 7. While UTP is routinely incorporated into RNA, dUTP is not normally incorporated into DNA. Instead, if dUTP is misincorporated into DNA, it can cause DNA damage. Therefore, dUTP can be considered as a teratogen or a mutagen. The extent of DNA damage caused by dUTP is highly dependent on the levels of the dUTP pyrophosphatase (dUTPase) and uracil-DNA glycosylase (UDG), which limits the intracellular accumulation of dUTP. Additionally, loss of viability following thymidylate synthase (TS) inhibition occurs as a consequence of the accumulation of dUTP in some cell lines and subsequent misincorporation of uracil into DNA (PMID: 11487279).

   

alpha-D-Ribose 1-methylphosphonate 5-triphosphate

alpha-D-Ribose 1-methylphosphonate 5-triphosphate

C6H16O16P4 (467.9389)


   

C.I. Pigment Yellow 100

5-Hydroxy-1-(4-sulphophenyl)-4-[(e)-2-(4-sulphophenyl)diazen-1-yl]-1H-pyrazole-3-carboxylic acid

C16H12N4O9S2 (468.0046)


FDA permitted colourant for food and food contact paper or board. FDA permitted colourant for food and food contact paper or board

   

2-[3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzoyl)imino]-4-oxo-5-thiazolidinylidene]-acetic acid, methyl ester

2-[3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzoyl)imino]-4-oxo-5-thiazolidinylidene]-acetic acid, methyl ester

C19H11Cl3N2O4S (467.9505)


   

Indigotin disulfonate sodium

disodium 3-oxo-2-[(2E)-3-oxo-5-sulfo-2,3-dihydro-1H-indol-2-ylidene]-2,3-dihydro-1H-indole-5-sulfonic acid

C16H10N2Na2O8S2 (467.9674)


Colour additive for food

   
   

4-(3-Chloro-2-cyanophenoxy)-N-(3,5-dichloro-4-pyridinyl)benzenesulfonohydrazide

4-(3-Chloro-2-cyanophenoxy)-N-(3,5-dichloro-4-pyridinyl)benzenesulfonohydrazide

C18H11Cl3N4O3S (467.9617)


   

2-[(4-Chlorobenzyl)sulfonyl]-3-[3,5-bis(trifluoromethyl)anilino]acrylonitrile

2-[(4-Chlorobenzyl)sulfonyl]-3-[3,5-bis(trifluoromethyl)anilino]acrylonitrile

C18H11ClF6N2O2S (468.0134)


   
   
   

5-acetoxy-2,10-dibromo-3-chloro-7alpha,8alpha-epoxy-alpha-chamigrene

5-acetoxy-2,10-dibromo-3-chloro-7alpha,8alpha-epoxy-alpha-chamigrene

C17H23Br2ClO3 (467.9702)


   

4, 19-Dibromo-3-ethyl-2, 20-dioxabicyclo[14.3.1]eicosa-1(19), 6, 9, 16-tetraen-12-yn-18-one, 9CI

4, 19-Dibromo-3-ethyl-2, 20-dioxabicyclo[14.3.1]eicosa-1(19), 6, 9, 16-tetraen-12-yn-18-one, 9CI

C20H22Br2O3 (467.9936)


   

2'-DEOXYURIDINE 5'-TRIPHOSPHATE

2'-DEOXYURIDINE 5'-TRIPHOSPHATE

C9H15N2O14P3 (467.9736)


   

Deoxyuridine triphosphate

Deoxyuridine triphosphate

C9H15N2O14P3 (467.9736)


   

2-Deoxyuridine 5-triphosphate

2-Deoxyuridine 5-triphosphate

C9H15N2O14P3 (467.9736)


   

Dibrompropamidine

Dibrompropamidine

C17H18Br2N4O2 (467.9796)


D - Dermatologicals > D08 - Antiseptics and disinfectants > D08A - Antiseptics and disinfectants > D08AC - Biguanides and amidines S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent D000890 - Anti-Infective Agents

   
   

dimethyl perfluoroazelate

dimethyl perfluoroazelate

C11H6F14O4 (468.0043)


   

2-Deoxythymidine-5-diphosphate trisodium salt

2-Deoxythymidine-5-diphosphate trisodium salt

C10H13N2Na3O11P2 (467.9688)


   

Magnesium hexafluoro-2,4-pentanedionate dihydrate

Magnesium hexafluoro-2,4-pentanedionate dihydrate

C12H12Mg3O15 (467.9728)


   

5-bromo-1,3-bis(bromomethyl)-2-octoxybenzene

5-bromo-1,3-bis(bromomethyl)-2-octoxybenzene

C16H23Br3O (467.9299)


   
   

2-(perfluoro-5-methylhexyl)ethyl acrylate

2-(perfluoro-5-methylhexyl)ethyl acrylate

C12H7F15O2 (468.0207)


   

2-[4-bromo-2-[1-(2,6-dichlorophenyl)pyrazole-4-carbonyl]phenoxy]acetic acid

2-[4-bromo-2-[1-(2,6-dichlorophenyl)pyrazole-4-carbonyl]phenoxy]acetic acid

C18H11BrCl2N2O4 (467.9279)


   

Clobenpropit dihydrobromide

Clobenpropit dihydrobromide

C14H19Br2ClN4S (467.9386)


Clobenpropit dihydrobromide is a potent histamine H3R antagonist/inverse agonist with a pEC50 of 8.07 for histamine H3LR[1]. Clobenpropit dihydrobromide acts as partial agonist at histamine H4 receptors (Ki 13 nM). Clobenpropit dihydrobromide also binds to serotonin 5-HT3 receptors (Ki 7.4 nM) and α2A/α2C adrenoceptors (Ki 17.4/7.8 nM)[2]. Clobenpropit dihydrobromide increases apoptosis[3].

   

1h,1h-perfluorooctyl methacrylate

1h,1h-perfluorooctyl methacrylate

C12H7F15O2 (468.0207)


   

ETHYL VIOLOGEN DIIODIDE

ETHYL VIOLOGEN DIIODIDE

C14H18I2N2 (467.9559)


   

N-CYANO-3-(IODOMETHYL)-4-(1H,1H-NONAFLUOROPENTYL)PYRROLIDINE

N-CYANO-3-(IODOMETHYL)-4-(1H,1H-NONAFLUOROPENTYL)PYRROLIDINE

C11H10F9IN2 (467.9745)


   

FD&C Yellow No. 5 free acid

FD&C Yellow No. 5 free acid

C16H12N4O9S2 (468.0046)


   

2-[3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzoyl)imino]-4-oxo-5-thiazolidinylidene]-acetic acid, methyl ester

2-[3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzoyl)imino]-4-oxo-5-thiazolidinylidene]-acetic acid, methyl ester

C19H11Cl3N2O4S (467.9505)


   
   

4-tert-butyl-N-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide

4-tert-butyl-N-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide

C18H18Br2N2O3 (467.9684)


   

(2S,5S,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

(2S,5S,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

C19H16Cl2N3O5S- (468.0188)


   
   

Dicloxacillin(1-)

Dicloxacillin(1-)

C19H16Cl2N3O5S- (468.0188)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams

   
   

7-Bromo-2-{(E)-1-[5-(2-nitrophenyl)-2-furyl]methylidene}[1,3]thiazolo[2,3:2,3]imidazo[4,5-B]pyridin-3(2H)-one

7-Bromo-2-{(E)-1-[5-(2-nitrophenyl)-2-furyl]methylidene}[1,3]thiazolo[2,3:2,3]imidazo[4,5-B]pyridin-3(2H)-one

C19H9BrN4O4S (467.9528)


   

dUTP

dUTP

C9H15N2O14P3 (467.9736)


A deoxyuridine phosphate having a triphosphate group at the 5-position.

   

(2r,3s,5r,6s,8r)-3,6-dibromo-8-[(3z)-1-chlorohex-3-en-5-yn-1-yl]-2-ethyloxocan-5-yl acetate

(2r,3s,5r,6s,8r)-3,6-dibromo-8-[(3z)-1-chlorohex-3-en-5-yn-1-yl]-2-ethyloxocan-5-yl acetate

C17H23Br2ClO3 (467.9702)


   

methyl 3',4-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-ene-6'-carboxylate

methyl 3',4-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-ene-6'-carboxylate

C17H23Br2ClO3 (467.9702)


   

methyl (1s,2s,3's,4's,6r,6's)-3',4-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-ene-6'-carboxylate

methyl (1s,2s,3's,4's,6r,6's)-3',4-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-ene-6'-carboxylate

C17H23Br2ClO3 (467.9702)


   

4,19-dibromo-3-ethyl-2,20-dioxabicyclo[14.3.1]icosa-1(19),6,9,16-tetraen-12-yn-18-one

4,19-dibromo-3-ethyl-2,20-dioxabicyclo[14.3.1]icosa-1(19),6,9,16-tetraen-12-yn-18-one

C20H22Br2O3 (467.9936)


   

(3s,4r,6e,9z)-4,19-dibromo-3-ethyl-2,20-dioxabicyclo[14.3.1]icosa-1(19),6,9,16-tetraen-12-yn-18-one

(3s,4r,6e,9z)-4,19-dibromo-3-ethyl-2,20-dioxabicyclo[14.3.1]icosa-1(19),6,9,16-tetraen-12-yn-18-one

C20H22Br2O3 (467.9936)