Exact Mass: 466.3784

Exact Mass Matches: 466.3784

Found 343 metabolites which its exact mass value is equals to given mass value 466.3784, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Vitamin K1 2,3-epoxide

(1aS,7aR)-1a-methyl-7a-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-1aH,2H,7H,7aH-naphtho[2,3-b]oxirene-2,7-dione

C31H46O3 (466.3447)

Vitamin K1 2,3-epoxide (CAS: 25486-55-9) is a vitamin K derivative. Vitamin K is needed for the posttranslational modification of certain proteins, mostly required for blood coagulation. Within the cell, vitamin K undergoes electron reduction to a reduced form of vitamin K (called vitamin K hydroquinone) by the enzyme vitamin K epoxide reductase (or VKOR). Another enzyme then oxidizes vitamin K hydroquinone to allow carboxylation of glutamate into gamma-carboxyglutamate (Gla). This enzyme is called the gamma-glutamyl carboxylase or the vitamin K-dependent carboxylase. The carboxylation reaction will only proceed if the carboxylase enzyme is able to oxidize vitamin K hydroquinone into vitamin K epoxide at the same time; the carboxylation and epoxidation reactions are said to be coupled reactions. Vitamin K epoxide is then re-converted into vitamin K by the vitamin K epoxide reductase. These two enzymes comprise the so-called vitamin K cycle. One of the reasons why vitamin K is rarely deficient in a human diet is because vitamin K is continually recycled in our cells. Vitamin K 2,3-epoxide is the substrate for vitamin K 2,3-epoxide reductase (VKOR) complex. Significantly increased level of serum vitamin K epoxide has been found in patients with familial multiple coagulation factor deficiency (PMID: 12384421). Accumulation of vitamin K1-2,3-epoxide in plasma is also a sensitive marker of the coumarin-like activity of drugs (PMID: 2401753). Vitamin K1 2,3-epoxide is a vitamin K derivative. Vitamin K needed for the posttranslational modification of certain proteins, mostly required for blood coagulation. Within the cell, Vitamin K undergoes electron reduction to a reduced form of Vitamin K (called Vitamin K hydroquinone) by the enzyme Vitamin K epoxide reductase (or VKOR). Another enzyme then oxidizes Vitamin K hydroquinone to allow carboxylation of Glutamate to Gamma-cabroxygluatmate (Gla); this enzyme is called the gamma-glutamyl carboxylase or the Vitamin K-dependent carboxylase. The carboxylation reaction will only proceed if the carboxylase enzyme is able to oxidize Vitamin K hydroquinone to vitamin K epoxide at the same time; the carboxylation and epoxidation reactions are said to be coupled reactions. Vitamin K epoxide is then re-converted to Vitamin K by the Vitamin K epoxide reductase. These two enzymes comprise the so-called Vitamin K cycle. One of the reasons why Vitamin K is rarely deficient in a human diet is because Vitamin K is continually recycled in our cells. Vitamin K 2,3-epoxide is the substrate for vitamin K 2,3-epoxide reductase (VKOR) complex. Significantly increased level of serum vitamin K epoxide has been found in patients with familial multiple coagulation factor deficiency. (PMID 12384421) Accumulation of vitamin K1-2,3-epoxide in plasma is also a sensitive marker of coumarin-like activity of drugs. (PMID 2401753) [HMDB]

ST 28:0;O5

campestan-2alpha,3alpha,6alpha,22R,23R-pentol

C28H50O5 (466.3658)

A brassinosteroid that is castasterone in which the oxo group at position 6 has been converted to a hydroxy group (the 6alpha-stereoisomer).

omega-Hydroxyphylloquinone

2-[(E)-16-hydroxy-3,7,11,15-tetramethylhexadec-2-enyl]-3-methylnaphthalene-1,4-dione

C31H46O3 (466.3447)

TetraHCA

3-hydroxy-2-methyl-6-{5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl}heptanoic acid

C27H46O6 (466.3294)

TetraHCA is considered to be practically insoluble (in water) and acidic

LysoSM(d18:0)

(2-{[(2S,3R)-2-amino-3-hydroxyoctadecyl phosphonato]oxy}ethyl)trimethylazanium

C23H51N2O5P (466.3535)

Sphingomyelin (d18:0/0:0) or LysoSM(d18:0) is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath which surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide. In humans, sphingomyelin is the only membrane phospholipid not derived from glycerol. Like all sphingolipids, SPH has a ceramide core (sphingosine bonded to a fatty acid via an amide linkage). In addition it contains one polar head group, which is either phosphocholine or phosphoethanolamine. The plasma membrane of cells is highly enriched in sphingomyelin and is considered largely to be found in the exoplasmic leaflet of the cell membrane. However, there is some evidence that there may also be a sphingomyelin pool in the inner leaflet of the membrane. Moreover, neutral sphingomyelinase-2 - an enzyme that breaks down sphingomyelin into ceramide has been found to localise exclusively to the inner leaflet further suggesting that there may be sphingomyelin present there. Sphingomyelin can accumulate in a rare hereditary disease called Niemann-Pick Disease, types A and B. Niemann-Pick disease is a genetically-inherited disease caused by a deficiency in the enzyme Sphingomyelinase, which causes the accumulation of Sphingomyelin in spleen, liver, lungs, bone marrow, and the brain, causing irreversible neurological damage. SMs play a role in signal transduction. Sphingomyelins are synthesized by the transfer of phosphorylcholine from phosphatidylcholine to a ceramide in a reaction catalyzed by sphingomyelin synthase. Sphingomyelin (d18:0/0:0) or LysoSM(d18:0)is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath which surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide. In humans, sphingomyelin is the only membrane phospholipid not derived from glycerol. Like all sphingolipids, SPH has a ceramide core (sphingosine bonded to a fatty acid via an amide linkage). In addition it contains one polar head group, which is either phosphocholine or phosphoethanolamine. The plasma membrane of cells is highly enriched in sphingomyelin and is considered largely to be found in the exoplasmic leaflet of the cell membrane. However, there is some evidence that there may also be a sphingomyelin pool in the inner leaflet of the membrane. Moreover, neutral sphingomyelinase-2 - an enzyme that breaks down sphingomyelin into ceramide has been found to localise exclusively to the inner leaflet further suggesting that there may be sphingomyelin present there. Sphingomyelin can accumulate in a rare hereditary disease called Niemann-Pick Disease, types A and B. Niemann-Pick disease is a genetically-inherited disease caused by a deficiency in the enzyme Sphingomyelinase, which causes the accumulation of Sphingomyelin in spleen, liver, lungs, bone marrow, and the brain, causing irreversible neurological damage. SMs play a role in signal transduction.

2,3-Epoxyphylloquinone

Naphth[2,3-b]oxirene-2,7-dione, 1a,7a-dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecenyl)-phylloquinone oxide

C31H46O3 (466.3447)

Vitamin K1 2,3-epoxide is a vitamin K derivative. Vitamin K needed for the posttranslational modification of certain proteins, mostly required for blood coagulation. Within the cell, Vitamin K undergoes electron reduction to a reduced form of Vitamin K (called Vitamin K hydroquinone) by the enzyme Vitamin K epoxide reductase (or VKOR). Another enzyme then oxidizes Vitamin K hydroquinone to allow carboxylation of Glutamate to Gamma-cabroxygluatmate (Gla); this enzyme is called the gamma-glutamyl carboxylase or the Vitamin K-dependent carboxylase. The carboxylation reaction will only proceed if the carboxylase enzyme is able to oxidize Vitamin K hydroquinone to vitamin K epoxide at the same time; the carboxylation and epoxidation reactions are said to be coupled reactions. Vitamin K epoxide is then re-converted to Vitamin K by the Vitamin K epoxide reductase. These two enzymes comprise the so-called Vitamin K cycle. One of the reasons why Vitamin K is rarely deficient in a human diet is because Vitamin K is continually recycled in our cells. Vitamin K 2,3-epoxide is the substrate for vitamin K 2,3-epoxide reductase (VKOR) complex. Significantly increased level of serum vitamin K epoxide has been found in patients with familial multiple coagulation factor deficiency. (PMID 12384421) Accumulation of vitamin K1-2,3-epoxide in plasma is also a sensitive marker of coumarin-like activity of drugs. (PMID 2401753) [HMDB]

28-Norbrassinolide

(1S,2R,4R,5S,7S,11S,12S,15R,16S)-15-[(2S,3R,4R)-3,4-dihydroxy-6-methylheptan-2-yl]-4,5-dihydroxy-2,16-dimethyl-9-oxatetracyclo[9.7.0.0²,⁷.0¹²,¹⁶]octadecan-8-one

C27H46O6 (466.3294)

28-norbrassinolide belongs to brassinolides and derivatives class of compounds. Those are cholestane based steroid lactones containing benzo[c]indeno[5,4-e]oxepin-3-one. 28-norbrassinolide is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 28-norbrassinolide can be found in tea and turnip, which makes 28-norbrassinolide a potential biomarker for the consumption of these food products.

6alpha-hydroxy-castasterone

14-(3,4-dihydroxy-5,6-dimethylheptan-2-yl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-4,5,8-triol

C28H50O5 (466.3658)

Corticatic acid E

Varanic acid

C24H46N6O3 (466.3631)

(4aR)-10c-Acetoxy-2.2.4ar.6at.6bc.9.9.12ac-octamethyl-(8atH.12btH)-Delta13.14a-octadecahydro-picen|3-Ac-3beta-11,13(18)-Oleanadien-3-ol|3beta-Acetoxy-oleana-11,13(18)-dien|3beta-acetoxy-oleana-11,13(18)-diene|3beta-Acetoxyolean-11,13(18)-diene|3beta-acetoxyolean-11,13-diene|Olean-11,13(18)-diene-3??-yl acetate|oleana-11,13(18)-dien-3beta-yl acetate|Oleana-11,13(18)-dienyl-3beta-acetat|oleana-11:13(18)-dien-3beta-yl acetate

(4aR)-10c-Acetoxy-2.2.4ar.6at.6bc.9.9.12ac-octamethyl-(8atH.12btH)-Delta13.14a-octadecahydro-picen|3-Ac-3beta-11,13(18)-Oleanadien-3-ol|3beta-Acetoxy-oleana-11,13(18)-dien|3beta-acetoxy-oleana-11,13(18)-diene|3beta-Acetoxyolean-11,13(18)-diene|3beta-acetoxyolean-11,13-diene|Olean-11,13(18)-diene-3??-yl acetate|oleana-11,13(18)-dien-3beta-yl acetate|Oleana-11,13(18)-dienyl-3beta-acetat|oleana-11:13(18)-dien-3beta-yl acetate

C32H50O2 (466.3811)

(all-E)-6,10,14,18,22,26-hexamethyl-heptacosa-5,9,13,17,21,25-hexaen-2-one|2,6,10,14,18,22-Hexamethyl-26-oxo-heptacosahexaen-(2.6.10.14.18.22)|6,10,14,18,22,26-Hexamethyl-heptacosa-5t,9t,13t,17t21t,25-hexaen-2-on|6,10,14,18,22,26-hexamethyl-heptacosa-5t,9t,13t,17t21t,25-hexaen-2-one|all-trans-Farnesylfarnesylaceton

(all-E)-6,10,14,18,22,26-hexamethyl-heptacosa-5,9,13,17,21,25-hexaen-2-one|2,6,10,14,18,22-Hexamethyl-26-oxo-heptacosahexaen-(2.6.10.14.18.22)|6,10,14,18,22,26-Hexamethyl-heptacosa-5t,9t,13t,17t21t,25-hexaen-2-on|6,10,14,18,22,26-hexamethyl-heptacosa-5t,9t,13t,17t21t,25-hexaen-2-one|all-trans-Farnesylfarnesylaceton

C33H54O (466.4174)

3-Ac-3beta-9(11),12-Oleanadien-3-ol|3-acetoxyolean-9,12-dien|3beta-acetoxy-olean-9(11),12-diene|3beta-acetoxy-olean-9,12-diene|3beta-Acetoxyolean-9(11),12-diene|acetic acid oleana-9(11),12-dien-3beta-yl ester|olean-9(11),12(13)-dien-3beta-yl acetate|oleana-9(11),12-dien-3-yl acetate|oleana-9(11):12-dien-3beta-yl acetate