Exact Mass: 466.2388968

Exact Mass Matches: 466.2388968

Found 500 metabolites which its exact mass value is equals to given mass value 466.2388968, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Androsterone glucuronide

(2S,3S,4S,5R,6R)-6-{[(1S,2S,5R,7S,10R,11S,15S)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-5-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid

C25H38O8 (466.2566548)

Androsterone glucuronide (ADT-G) is one of the major circulating C19-steroid metabolites in humans. Human and monkey are unique in having high levels of circulating ADT-G. Furthermore, the plasma levels of these glucuronide derivatives reflect the peripheral tissue conversion of adrenal and gonadal precursor C19-steroids to active androgens in various pathophysiological conditions. Identification and characterization of human UDP-glucuronosyltransferase 2B (UGT2Bs) demonstrated the major role that these enzymes play in androgen conjugation, with UGT2B15 and UGT2B17 (EC 2.4.1.17) being the major androsterone-conjugating isoforms. Exaggerated androsterone metabolism, is observed in hyper-androgenic as well as in some normo-androgenic women with acne and androsterone glucuronide could be a marker in differentiating acne and hirsutism in hyperandrogenic women. Present data shows that the most practical and probably only valid means of assessing androgenic activity in women is to measure ADT-G, the metabolite that accounts for 93\\% of the total androgen glucuronide derivatives. (PMID: 12943709, 12445184, 16621522) [HMDB] Androsterone glucuronide (ADT-G) is one of the major circulating C19-steroid metabolites in humans. Human and monkey are unique in having high levels of circulating ADT-G. Furthermore, the plasma levels of these glucuronide derivatives reflect the peripheral tissue conversion of adrenal and gonadal precursor C19-steroids to active androgens in various pathophysiological conditions. Identification and characterization of human UDP-glucuronosyltransferase 2B (UGT2Bs) demonstrated the major role that these enzymes play in androgen conjugation, with UGT2B15 and UGT2B17 (EC 2.4.1.17) being the major androsterone-conjugating isoforms. Exaggerated androsterone metabolism, is observed in hyper-androgenic as well as in some normo-androgenic women with acne and androsterone glucuronide could be a marker in differentiating acne and hirsutism in hyperandrogenic women. Present data shows that the most practical and probably only valid means of assessing androgenic activity in women is to measure ADT-G, the metabolite that accounts for 93\\% of the total androgen glucuronide derivatives. (PMID: 12943709, 12445184, 16621522). D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones

T2 Toxin

11-(Acetyloxy)-2-[(acetyloxy)methyl]-10-hydroxy-1,5-dimethyl-8-oxaspiro[oxirane-2,12-tricyclo[7.2.1.0²,⁷]dodecan]-5-en-4-yl 3-methylbutanoic acid

C24H34O9 (466.2202714)

T2 Toxin is isolated from Fusarium species and Trichoderma lignorum. T2 Toxin is an important mycotoxin occurring naturally in various agricultural products. Isolated from Fusarium subspecies and Trichoderma lignorum. Important mycotoxin occurring naturally in various agricultural products D009676 - Noxae > D011042 - Poisons > D014255 - Trichothecenes D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins T-2 Toxin (T-2 Mycotoxin) is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains, LD50 values of T-2 Toxin in mice and rats are 5.2 and 1.5 mg/kg BWa,respectively [1]. T-2 Toxin (T-2 Mycotoxin) can be transformed into a variety of metabolite, the typical metabolites of T-2 toxin in animals are HT-2 toxin and T-2-triol, which are hydrolysates[1]. T-2 Toxin (T-2 Mycotoxin) is an inhibitor of protein synthesis resulting from binding peptidyltransferase, which is an integral part of the 60s ribosomal subunit. T-2 Toxin (T-2 Mycotoxin) inhibits the synthesis of DNA and RNA, interferes with the metabolism of membrane phospholipids, and increases the level of liver lipid peroxides[1]. T-2 Toxin (T-2 Mycotoxin) induces apoptosis in the immune system, gastrointestinal tissues, and fetal tissues[2].

5β-Androstan-3α-ol-17-One Glucosiduronate

(2S,3S,4S,5R,6R)-6-{[(1S,2S,5R,7R,10R,11S,15S)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-5-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid

C25H38O8 (466.2566548)

Etiocholanolone glucuronide is a natural human metabolite of etiocholanolone generated in the liver by UDP glucuonyltransferase. Etiocholanolone (or 5-isoandrosterone) is a metabolite of testosterone. Classified a ketosteroid, it causes fever, immunostimulation and leukocytosis. Glucuronidation is used to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys. [HMDB] Etiocholanolone glucuronide is a natural human metabolite of etiocholanolone generated in the liver by UDP glucuonyltransferase. Etiocholanolone (or 5-isoandrosterone) is a metabolite of testosterone. Classified a ketosteroid, it causes fever, immunostimulation and leukocytosis. Glucuronidation is used to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys. Etiocholanolone glucuronide. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=3602-09-3 (retrieved 2024-06-29) (CAS RN: 3602-09-3). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

5-alpha-Dihydrotestosterone glucuronide

(2S,3S,4S,5R,6R)-6-{[(1S,2S,7S,10R,11S,14S,15S)-2,15-dimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid

C25H38O8 (466.2566548)

5-alpha-Dihydrotestosterone glucuronide is a natural human metabolite of 5alpha-Dihydrotestosterone generated in the liver by UDP glucuonyltransferase. Glucuronidation is used to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys. 5-alpha-Dihydrotestosterone glucuronide is a natural human metabolite of 5alpha-Dihydrotestosterone generated in the liver by UDP glucuonyltransferase. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones

Dolichyl b-D-glucosyl phosphate

{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}({[(6Z)-3,7,11-trimethyldodeca-6,10-dien-1-yl]oxy})phosphinic acid

C21H39O9P (466.23315740000004)

Dolichyl β-D-glucosyl phosphate is a polyisoprenyl phosphate monosaccharide. Biosynthesis is by Glucosyltransferase in liver mitochondria. (PubMed ID 6450044 ) [HMDB] Dolichyl β-D-glucosyl phosphate is a polyisoprenyl phosphate monosaccharide. Biosynthesis is by Glucosyltransferase in liver mitochondria. (PubMed ID 6450044 ).

3-alpha-hydroxy-5-alpha-androstane-17-one 3-D-glucuronide

(3S,5R,6S)-6-{[(1S,2S,5R,7S,10R,11S,15S)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-5-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid

C25H38O8 (466.2566548)

3-alpha-hydroxy-5-alpha-androstane-17-one 3-D-glucuronide is a natural human metabolite of 3-alpha-hydroxy-5-alpha-androstane-17-one generated in the liver by UDP glucuonyltransferase. Glucuronidation is used to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys.

5alpha-Androstan-17beta-ol-3-one glucosiduronate

6-({2,15-dimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid

C25H38O8 (466.2566548)

4-[3-[4-(Diphenylmethyl)-1-piperazinyl]-2-hydroxypropoxy]-1H-indole-2-carbonitrile

C29H30N4O2 (466.23686399999997)

D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents

DG(2:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0)

(2S)-1-(Acetyloxy)-3-hydroxypropan-2-yl (5R,6R,7Z,11E,13E,15S,17Z)-5,6,15-trihydroxyicosa-7,9,11,13,17-pentaenoic acid

C25H38O8 (466.2566548)

DG(2:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) belongs to the family of Diacylglycerols. These are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. DG(2:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) is also a substrate of diacylglycerol kinase. It is involved in the phospholipid metabolic pathway.

DG(20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/2:0/0:0)

(2S)-2-(Acetyloxy)-3-hydroxypropyl (5S,6S,7Z,11E,13E,15R,17Z)-5,6,15-trihydroxyicosa-7,9,11,13,17-pentaenoic acid

C25H38O8 (466.2566548)

DG(20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/2:0/0:0) belongs to the family of Diacylglycerols. These are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. DG(20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/2:0/0:0) is also a substrate of diacylglycerol kinase. It is involved in the phospholipid metabolic pathway.

DG(2:0/0:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15))

(2R)-3-(Acetyloxy)-2-hydroxypropyl (5S,6S,7Z,9Z,11E,13E,15R,17Z)-5,6,15-trihydroxyicosa-7,9,11,13,17-pentaenoic acid

C25H38O8 (466.2566548)

DG(2:0/0:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)) belongs to the family of Diacylglycerols. These are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. It is involved in the phospholipid metabolic pathway.

DG(20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0/2:0)

(2S)-3-(Acetyloxy)-2-hydroxypropyl (5S,6S,7Z,9Z,11E,13E,15R,17Z)-5,6,15-trihydroxyicosa-7,9,11,13,17-pentaenoic acid

C25H38O8 (466.2566548)

DG(20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0/2:0) belongs to the family of Diacylglycerols. These are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. It is involved in the phospholipid metabolic pathway.

A tetracyclic triterpenoid that is 4,4,8-trimethylandrosta-1,14-diene substituted by a oxo groups at positions 3 and 16, an acetoxy group at position 7 and a 2-oxo-2,5-dihydrofuran-3-yl group at position 17. It has been isolated from Azadirachta indica.

Pachyclavulariolide M

C24H34O9 (466.2202714)

Salpichrolide G

C28H34O6 (466.2355264)

Mniopetal D

C25H38O8 (466.2566548)

Ajugamarin C1

C24H34O9 (466.2202714)

Cardivin C

C24H34O9 (466.2202714)

A germacranolide isolated from the aerial parts of Carpesium divaricatum. It exhibits cytotoxicity against the human tumor cells, A-549 (nonsmall cell lung), SK-OV-3 (ovary), SK-MEL-2 (skin), XF-498 (central nervous system) and HCT-15 (colon).

Excavatolide E

C24H34O9 (466.2202714)

Leucasdin A

C25H38O8 (466.2566548)

Fissistin

C28H34O6 (466.2355264)

Isofissistin

(1R-trans)- (2,5-Dihydroxy-3,4,6-trimethoxyphenyl)[3-(4-methyl-3-pentenyl)-6-phenyl-3-cyclohexen-1-yl]methanone

C28H34O6 (466.2355264)

Neocaesalpin C

C24H34O9 (466.2202714)

Withaphysalin A

(1R,2R,5S,6R,12S,13R)-6-[(2R)-4,5-Dimethyl-6-oxo-2,3-dihydropyran-2-yl]-2-hydroxy-6,13-dimethyl-7-oxapentacyclo[10.8.0.02,9.05,9.013,18]icosa-15,18-diene-8,14-dione

C28H34O6 (466.2355264)

Halisulfate 8

C25H38O6S (466.2388968)

17beta-hydroxyazadiradione

C28H34O6 (466.2355264)

Epoxyazadiradione

C28H34O6 (466.2355264)

Epoxyazadiradione is a limonoid purified from neem (Azadirachta indica) fruits. Epoxyazadiradione inhibits the tautomerase activity of MIF of both human (huMIF) and malaria parasites (Plasmodium falciparum (PfMIF) and Plasmodium yoelii (PyMIF)) non-competitively in a reversible fashion (Ki, 2.11-5.23 μM). Epoxyazadiradione has the potential against proinflammatory reactions induced by MIF of both malaria parasites and human[1].

Deoxygedunin

C28H34O6 (466.2355264)

C28H34O6

C28H34O6 (466.2355264)

(1S,2S,3R,4R,6R)-diangeloyloxy-3,4-epoxy-2,10,11-trihydroxybisabol-7(14)-ene|1beta,8-diangeloyloxy-3beta,4beta-epoxy-2beta,10,11-trihydroxybisabol-7(14)-ene

C25H38O8 (466.2566548)

NSC630597

C28H34O6 (466.2355264)

6alpha,7alpha:22,26:24,25-triepoxy-5,26-dihydroxy-17-(13-18)-abeo-5alpha-ergosta-2,13,15,17-tetraen-1-one

C28H34O6 (466.2355264)

Asebotoxin IX

C25H38O8 (466.2566548)

nicaphysalin E|withahisolide F|[(20S,22S)-6alpha,7alpha-epoxy-22-formyloxy-5alpha-hydroxy-27-nor-17(13?18)-abeo-5alpha-ergost-2,13,15,17-tetraene]

C28H34O6 (466.2355264)

Nicandrenone

C28H34O6 (466.2355264)

C27H34N2O5

C27H34N2O5 (466.24675940000003)

proceranone

C28H34O6 (466.2355264)

17beta-hydroxy-6alpha-acetoxyazadiradione

C28H34O6 (466.2355264)

16(R)-6alpha,11beta-dihydroxy-17-methoxy-3beta,7beta-diacetoxy-ent-kaur-15-one|xindongnin G

C25H38O8 (466.2566548)

6alpha-hydroxyazadiradione|6??-Hydroxyazadiradione|nimonol

C28H34O6 (466.2355264)

12-Deoxyphorbol 13-phenylacetate

C28H34O6 (466.2355264)

clerodinin A|clerodinin B|lupulin D|O15-De-Et,O15-Methyl,15-Epimer-Clerodinin C

C25H38O8 (466.2566548)

Val-Trp-Tyr

C25H30N4O5 (466.221609)

11,12-Di-O-acetyl-marsectohexol|11,12-di-O-acetylmarsectohexol|11.12-Di-O-acetyl-marsectohexol|12-O-acetyllanceogenin

C25H38O8 (466.2566548)

(E)-3,7-dimethyl-1-O-6)-beta-D-glucopyranosyl>-oct-2-en-7-ol

C21H38O11 (466.24139979999995)

dicitrinone A

C28H34O6 (466.2355264)

Asebotoxin-IX

C25H38O8 (466.2566548)

6-acetoxy-7alpha-hydroxy-3-oxo-14beta,15beta-epoxymeliac-1,5-diene

C28H34O6 (466.2355264)

1,6,9-trihydroxy-3-(1-hydroxy-1-methylethyl)-10-isobutyryl-5,5-dimethyl-8-(3-methylbut-2-enyl)-4-oxabicyclo[6.3.1]dodec-9-ene-11,12-dione|garcinielliptone HF

C25H38O8 (466.2566548)

2,3,22beta-trihydroxy-24,29-dinor-1,3,5(10),7-friedelatetraene-6,21-dione-23-al

C28H34O6 (466.2355264)

(1beta,2beta,3beta,4beta,6beta)-3,4-epoxybisabol-7(14)-ene-1,2,8,10,11-pentol 2,10-diangelate|(2Z)-2-methylbut-2-enoic acid (1RS,2SR,3SR,4RS,6RS)-4-(2,5-dihydroxy-5-methyl-1-methylene-4-{[(2Z)-2-methyl-1-oxobut-2-en-1-yl]oxy}hexyl)-3-hydroxy-1-methyl-7-oxabicyclo[4.1.0]hept-2-yl ester

(1beta,2beta,3beta,4beta,6beta)-3,4-epoxybisabol-7(14)-ene-1,2,8,10,11-pentol 2,10-diangelate|(2Z)-2-methylbut-2-enoic acid (1RS,2SR,3SR,4RS,6RS)-4-(2,5-dihydroxy-5-methyl-1-methylene-4-{[(2Z)-2-methyl-1-oxobut-2-en-1-yl]oxy}hexyl)-3-hydroxy-1-methyl-7-oxabicyclo[4.1.0]hept-2-yl ester

C25H38O8 (466.2566548)

garciniacowone

C28H34O6 (466.2355264)

4-epi-aubergenone 11-O-2,3-di-O-acetyl-alpha-L-rhamnopyranoside

C25H38O8 (466.2566548)

4-epi-aubergenone 11-O-2,4-di-O-acetyl-alpha-L-rhamnopyranoside

C25H38O8 (466.2566548)

rel-(1R,4R)-3,4-dihydro-1,6,8-trihydroxy-1,4,7-tris(3-methylbut-2-en-1-yl)-1H-xanthene-2,9-dione

C28H34O6 (466.2355264)

2beta,8-diangeloyloxy-3beta,4beta-epoxy-1beta,10,11-trihydroxybisabol-7(14)-ene

C25H38O8 (466.2566548)

walsuranin C

C28H34O6 (466.2355264)

2beta,8-diangeloyloxy-1beta,3beta,4alpha,11-tetrahydroxybisabol-7(14),9-diene

C25H38O8 (466.2566548)

walsucochinoid K

C28H34O6 (466.2355264)

Monodontamide A

C25H30N4O5 (466.221609)

(20S,22R,24S,25S,26R)-5alpha,6alpha:22,26:24,25-triepoxy-12beta,26-dihydroxy-17(13?18)abeo-ergosta-2,13,15,17-tetraen-1-one|salpichrolide T

C28H34O6 (466.2355264)

Withaphysalin D

14-Hydroxy-18,20:22,26-diepoxyergosta-3,5,24-triene-1,18,26-trione

C28H34O6 (466.2355264)

(rel-5S,6R,8R,9R,10S,13S,15R)-6-acetoxy-9,13:15,16-diepoxy-15-methoxylabdane|3alpha,8beta-diacetoxy-9,13;15,16-diepoxy-15beta-methoxylabdan-7-one|leosibirinone A

C25H38O8 (466.2566548)

Cylindramide

C27H34N2O5 (466.24675940000003)

(20R,22R)-5beta,6beta-14alpha,15alpha-21,24-triepoxy-1-oxowitha-2,25(27)-dien-22,26-olide|daturalicin

C28H34O6 (466.2355264)

erinacine J

C25H38O8 (466.2566548)

(22R,Z)-16beta,27-dihydroxy-1,4-dioxo-witha-2,5,17(20),24-tetraenolide

C28H34O6 (466.2355264)

(25S)-6alpha,7alpha;24,25-diepoxy-5,22betaF-dihydroxy-1-oxo-17(13=>18)-abeo-5alpha,24betaH-ergosta-2,13,15,17-tetraen-26-al

C28H34O6 (466.2355264)

1,2alpha-epoxyazadiradione|epoxyazadiradione

C28H34O6 (466.2355264)

6-geranyl-5-hydroxy-3,4,7-trimethoxyflavanone

C28H34O6 (466.2355264)

17-Hydroxyazadiradione|17beta-hydroxyazadiradione

C28H34O6 (466.2355264)

Trp Val Tyr

C25H30N4O5 (466.221609)

(2S)-OMPT

(2S)-3-[(hydroxymercaptophosphinyl)oxy]-2-methoxypropyl ester, 9Z-octadecenoic acid, triethyl ammonium salt

C22H43O6PS (466.25178280000006)

Trp Tyr Val

C25H30N4O5 (466.221609)

Tyr Trp Val

C25H30N4O5 (466.221609)

Val Tyr Trp

C25H30N4O5 (466.221609)

nimbinin

17-(3-furyl)-4,4,10,13-tetramethyl-3,16-dioxo- 3,4,5,6,7,8,9,10,11,12,13,15,16,17-tetradecahydro-20- oxacyclopropa[14,15]cyclopenta[a]phenathren-7-yl acetate

C28H34O6 (466.2355264)

Epoxyazadiradione is a limonoid that is azadiradione with an epoxy group across positions 14 and 15. Isolated from Azadirachta indica it exhibits insecticidal activitry against mosquitoes. It has a role as an anti-inflammatory agent, an insecticide and a plant metabolite. It is an acetate ester, a cyclic terpene ketone, a member of furans, a limonoid, an epoxide and a pentacyclic triterpenoid. It is functionally related to an azadiradione. Epoxyazadiradione is a natural product found in Azadirachta indica and Chisocheton siamensis with data available. A limonoid that is azadiradione with an epoxy group across positions 14 and 15. Isolated from Azadirachta indica it exhibits insecticidal activitry against mosquitoes. Epoxyazadiradione is a limonoid purified from neem (Azadirachta indica) fruits. Epoxyazadiradione inhibits the tautomerase activity of MIF of both human (huMIF) and malaria parasites (Plasmodium falciparum (PfMIF) and Plasmodium yoelii (PyMIF)) non-competitively in a reversible fashion (Ki, 2.11-5.23 μM). Epoxyazadiradione has the potential against proinflammatory reactions induced by MIF of both malaria parasites and human[1].

Deoxygedunin_major

C28H34O6 (466.2355264)

Ala Phe Met Val

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-phenylpropanamido]-4-(methylsulfanyl)butanamido]-3-methylbutanoic acid

C22H34N4O5S (466.22497940000005)

Ala Phe Val Met

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-phenylpropanamido]-3-methylbutanamido]-4-(methylsulfanyl)butanoic acid

C22H34N4O5S (466.22497940000005)

Ala Ile Thr Tyr

(2S)-2-[(2S,3R)-2-[(2S,3S)-2-[(2S)-2-aminopropanamido]-3-methylpentanamido]-3-hydroxybutanamido]-3-(4-hydroxyphenyl)propanoic acid