Exact Mass: 464.178592

Exact Mass Matches: 464.178592

Found 1 metabolites which its exact mass value is equals to given mass value 464.178592, within given mass tolerance error 2.56E-9 dalton. Try search metabolite list with more accurate mass tolerance error 5.12E-10 dalton.

Amn082 dihydrochloride

Amn082 dihydrochloride

C28H30Cl2N2 (464.178592)


AMN082, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 potently inhibits cAMP accumulation and stimulates GTPγS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects[1][2].