Exact Mass: 464.178592
Exact Mass Matches: 464.178592
Found 5 metabolites which its exact mass value is equals to given mass value 464.178592,
within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error
0.0002 dalton.
Amn082 dihydrochloride
Amn082 dihydrochloride
AMN082, a selective, orally active, and brain penetrant mGluR7 agonist, directly activates receptor signaling via an allosteric site in the transmembrane domain. AMN082 potently inhibits cAMP accumulation and stimulates GTPγS binding (EC50 values, 64-290 nM) at transfected mammalian cells expressing mGluR7. AMN082 shows selectivity over other mGluR subtypes and selected ionotropic glutamate receptors. Antidepressant effects[1][2].
n-[(3s,4r,7r,8r)-8-(acetyloxy)-7-butyl-4-methyl-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid
n-[(3s,4r,7r,8r)-8-(acetyloxy)-7-butyl-4-methyl-2,6-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzenecarboximidic acid
2-hydroxy-3-[(hydroxymethylidene)amino]-n-{2,6,8-trimethyl-7-[(2-methylpropanoyl)oxy]-4,9-dioxo-1,5-dioxonan-3-yl}benzenecarboximidic acid
2-hydroxy-3-[(hydroxymethylidene)amino]-n-{2,6,8-trimethyl-7-[(2-methylpropanoyl)oxy]-4,9-dioxo-1,5-dioxonan-3-yl}benzenecarboximidic acid