Exact Mass: 432.2332
Exact Mass Matches: 432.2332
Found 74 metabolites which its exact mass value is equals to given mass value 432.2332,
within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error
4.0E-5 dalton.
Buclizine
1-((4-Chlorophenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)methyl)piperazine
Buclizine is only found in individuals that have used or taken this drug. It is an antihistamine of the piperazine derivative family. [Wikipedia]Vomiting (emesis) is essentially a protective mechanism for removing irritant or otherwise harmful substances from the upper GI tract. Emesis or vomiting is controlled by the vomiting centre in the medulla region of the brain, an important part of which is the chemotrigger zone (CTZ). The vomiting centre possesses neurons which are rich in muscarinic cholinergic and histamine containing synapses. These types of neurons are especially involved in transmission from the vestibular apparatus to the vomiting centre. Motion sickness principally involves overstimulation of these pathways due to various sensory stimuli. Hence the action of buclizine which acts to block the histamine receptors in the vomiting centre and thus reduce activity along these pathways. Furthermore since buclizine possesses anti-cholinergic properties as well, the muscarinic receptors are similarly blocked. R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AE - Piperazine derivatives D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
Buclizine
Buclizine
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AE - Piperazine derivatives D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
Ala Lys Asn Thr
(2S,3R)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-3-carbamoylpropanamido]-3-hydroxybutanoic acid
Ala Lys Gln Ser
(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-4-carbamoylbutanamido]-3-hydroxypropanoic acid
Ala Lys Ser Gln
(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-3-hydroxypropanamido]-4-carbamoylbutanoic acid
Ala Lys Thr Asn
(2S)-2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-3-hydroxybutanamido]-3-carbamoylpropanoic acid
Ala Asn Lys Thr
(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]hexanamido]-3-hydroxybutanoic acid
Ala Asn Thr Lys
(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]-3-hydroxybutanamido]hexanoic acid
Ala Gln Lys Ser
(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-aminopropanamido]-4-carbamoylbutanamido]hexanamido]-3-hydroxypropanoic acid
Ala Gln Ser Lys
(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-4-carbamoylbutanamido]-3-hydroxypropanamido]hexanoic acid
Ala Ser Lys Gln
(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-hydroxypropanamido]hexanamido]-4-carbamoylbutanoic acid
Ala Ser Gln Lys
(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-hydroxypropanamido]-4-carbamoylbutanamido]hexanoic acid
Ala Thr Lys Asn
(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-aminopropanamido]-3-hydroxybutanamido]hexanamido]-3-carbamoylpropanoic acid
Ala Thr Asn Lys
(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-aminopropanamido]-3-hydroxybutanamido]-3-carbamoylpropanamido]hexanoic acid
Gly Lys Gln Thr
(2S,3R)-2-[(2S)-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]-4-carbamoylbutanamido]-3-hydroxybutanoic acid
Gly Lys Thr Gln
(2S)-2-[(2S,3R)-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]-3-hydroxybutanamido]-4-carbamoylbutanoic acid
Gly Gln Lys Thr
(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]hexanamido]-3-hydroxybutanoic acid
Gly Gln Thr Lys
(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]-3-hydroxybutanamido]hexanoic acid
Gly Thr Lys Gln
(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-(2-aminoacetamido)-3-hydroxybutanamido]hexanamido]-4-carbamoylbutanoic acid
Gly Thr Gln Lys
(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-(2-aminoacetamido)-3-hydroxybutanamido]-4-carbamoylbutanamido]hexanoic acid
Lys Ala Asn Thr
(2S,3R)-2-[(2S)-3-carbamoyl-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]propanamido]propanamido]-3-hydroxybutanoic acid
Lys Ala Gln Ser
(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]propanamido]butanamido]-3-hydroxypropanoic acid
Lys Ala Ser Gln
(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]propanamido]-3-hydroxypropanamido]butanoic acid
Lys Ala Thr Asn
(2S)-3-carbamoyl-2-[(2S,3R)-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]propanamido]-3-hydroxybutanamido]propanoic acid
Lys Gly Gln Thr
(2S,3R)-2-[(2S)-4-carbamoyl-2-{2-[(2S)-2,6-diaminohexanamido]acetamido}butanamido]-3-hydroxybutanoic acid
Lys Gly Thr Gln
(2S)-4-carbamoyl-2-[(2S,3R)-2-{2-[(2S)-2,6-diaminohexanamido]acetamido}-3-hydroxybutanamido]butanoic acid
Lys Asn Ala Thr
(2S,3R)-2-[(2S)-2-[(2S)-3-carbamoyl-2-[(2S)-2,6-diaminohexanamido]propanamido]propanamido]-3-hydroxybutanoic acid
Lys Asn Thr Ala
(2S)-2-[(2S,3R)-2-[(2S)-3-carbamoyl-2-[(2S)-2,6-diaminohexanamido]propanamido]-3-hydroxybutanamido]propanoic acid
Lys Gln Ala Ser
(2S)-2-[(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2,6-diaminohexanamido]butanamido]propanamido]-3-hydroxypropanoic acid
Lys Gln Gly Thr
(2S,3R)-2-{2-[(2S)-4-carbamoyl-2-[(2S)-2,6-diaminohexanamido]butanamido]acetamido}-3-hydroxybutanoic acid
Lys Gln Ser Ala
(2S)-2-[(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2,6-diaminohexanamido]butanamido]-3-hydroxypropanamido]propanoic acid
Lys Gln Thr Gly
2-[(2S,3R)-2-[(2S)-4-carbamoyl-2-[(2S)-2,6-diaminohexanamido]butanamido]-3-hydroxybutanamido]acetic acid
Lys Ser Ala Gln
(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxypropanamido]propanamido]butanoic acid
Lys Ser Gln Ala
(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxypropanamido]butanamido]propanoic acid
Lys Thr Ala Asn
(2S)-3-carbamoyl-2-[(2S)-2-[(2S,3R)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxybutanamido]propanamido]propanoic acid
Lys Thr Gly Gln
(2S)-4-carbamoyl-2-{2-[(2S,3R)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxybutanamido]acetamido}butanoic acid
Lys Thr Asn Ala
(2S)-2-[(2S)-3-carbamoyl-2-[(2S,3R)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxybutanamido]propanamido]propanoic acid
Lys Thr Gln Gly
2-[(2S)-4-carbamoyl-2-[(2S,3R)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxybutanamido]butanamido]acetic acid
Asn Ala Lys Thr
(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]hexanamido]-3-hydroxybutanoic acid
Asn Ala Thr Lys
(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]-3-hydroxybutanamido]hexanoic acid
Asn Lys Ala Thr
(2S,3R)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-3-carbamoylpropanamido]hexanamido]propanamido]-3-hydroxybutanoic acid
Asn Lys Thr Ala
(2S)-2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-amino-3-carbamoylpropanamido]hexanamido]-3-hydroxybutanamido]propanoic acid
Asn Thr Ala Lys
(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxybutanamido]propanamido]hexanoic acid
Asn Thr Lys Ala
(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxybutanamido]hexanamido]propanoic acid
Gln Ala Lys Ser
(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]propanamido]hexanamido]-3-hydroxypropanoic acid
Gln Ala Ser Lys
(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]propanamido]-3-hydroxypropanamido]hexanoic acid
Gln Gly Lys Thr
(2S,3R)-2-[(2S)-6-amino-2-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}hexanamido]-3-hydroxybutanoic acid
Gln Gly Thr Lys
(2S)-6-amino-2-[(2S,3R)-2-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}-3-hydroxybutanamido]hexanoic acid
Gln Lys Ala Ser
(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-4-carbamoylbutanamido]hexanamido]propanamido]-3-hydroxypropanoic acid
Gln Lys Gly Thr
(2S,3R)-2-{2-[(2S)-6-amino-2-[(2S)-2-amino-4-carbamoylbutanamido]hexanamido]acetamido}-3-hydroxybutanoic acid
Gln Lys Ser Ala
(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-4-carbamoylbutanamido]hexanamido]-3-hydroxypropanamido]propanoic acid
Gln Lys Thr Gly
2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-amino-4-carbamoylbutanamido]hexanamido]-3-hydroxybutanamido]acetic acid
Gln Ser Ala Lys
(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxypropanamido]propanamido]hexanoic acid
Gln Ser Lys Ala
(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxypropanamido]hexanamido]propanoic acid
Gln Thr Gly Lys
(2S)-6-amino-2-{2-[(2S,3R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxybutanamido]acetamido}hexanoic acid
Gln Thr Lys Gly
2-[(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxybutanamido]hexanamido]acetic acid
Ser Ala Lys Gln
(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]propanamido]hexanamido]-4-carbamoylbutanoic acid
Ser Ala Gln Lys
(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]propanamido]-4-carbamoylbutanamido]hexanoic acid
Ser Lys Ala Gln
(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-3-hydroxypropanamido]hexanamido]propanamido]-4-carbamoylbutanoic acid
Ser Lys Gln Ala
(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-3-hydroxypropanamido]hexanamido]-4-carbamoylbutanamido]propanoic acid
Ser Gln Ala Lys
(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-carbamoylbutanamido]propanamido]hexanoic acid
Ser Gln Lys Ala
(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-carbamoylbutanamido]hexanamido]propanoic acid
Thr Ala Lys Asn
(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]propanamido]hexanamido]-3-carbamoylpropanoic acid
Thr Ala Asn Lys
(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]propanamido]-3-carbamoylpropanamido]hexanoic acid
Thr Gly Lys Gln
(2S)-2-[(2S)-6-amino-2-{2-[(2S,3R)-2-amino-3-hydroxybutanamido]acetamido}hexanamido]-4-carbamoylbutanoic acid
Thr Gly Gln Lys
(2S)-6-amino-2-[(2S)-2-{2-[(2S,3R)-2-amino-3-hydroxybutanamido]acetamido}-4-carbamoylbutanamido]hexanoic acid
Thr Lys Ala Asn
(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanamido]propanamido]-3-carbamoylpropanoic acid
Thr Lys Gly Gln
(2S)-2-{2-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanamido]acetamido}-4-carbamoylbutanoic acid
Thr Lys Asn Ala
(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanamido]-3-carbamoylpropanamido]propanoic acid
Thr Lys Gln Gly
2-[(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanamido]-4-carbamoylbutanamido]acetic acid
Thr Asn Ala Lys
(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carbamoylpropanamido]propanamido]hexanoic acid
Thr Asn Lys Ala
(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carbamoylpropanamido]hexanamido]propanoic acid
Thr Gln Gly Lys
(2S)-6-amino-2-{2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carbamoylbutanamido]acetamido}hexanoic acid
Thr Gln Lys Gly
2-[(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carbamoylbutanamido]hexanamido]acetic acid
