Exact Mass: 432.2332

Exact Mass Matches: 432.2332

Found 74 metabolites which its exact mass value is equals to given mass value 432.2332, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

Buclizine

1-((4-Chlorophenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)methyl)piperazine

C28H33ClN2 (432.2332)


Buclizine is only found in individuals that have used or taken this drug. It is an antihistamine of the piperazine derivative family. [Wikipedia]Vomiting (emesis) is essentially a protective mechanism for removing irritant or otherwise harmful substances from the upper GI tract. Emesis or vomiting is controlled by the vomiting centre in the medulla region of the brain, an important part of which is the chemotrigger zone (CTZ). The vomiting centre possesses neurons which are rich in muscarinic cholinergic and histamine containing synapses. These types of neurons are especially involved in transmission from the vestibular apparatus to the vomiting centre. Motion sickness principally involves overstimulation of these pathways due to various sensory stimuli. Hence the action of buclizine which acts to block the histamine receptors in the vomiting centre and thus reduce activity along these pathways. Furthermore since buclizine possesses anti-cholinergic properties as well, the muscarinic receptors are similarly blocked. R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AE - Piperazine derivatives D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist

   

Buclizine

Buclizine

C28H33ClN2 (432.2332)


R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AE - Piperazine derivatives D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist

   

Ala Lys Asn Thr

(2S,3R)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-3-carbamoylpropanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Ala Lys Gln Ser

(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-4-carbamoylbutanamido]-3-hydroxypropanoic acid

C17H32N6O7 (432.2332)


   

Ala Lys Ser Gln

(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-3-hydroxypropanamido]-4-carbamoylbutanoic acid

C17H32N6O7 (432.2332)


   

Ala Lys Thr Asn

(2S)-2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-3-hydroxybutanamido]-3-carbamoylpropanoic acid

C17H32N6O7 (432.2332)


   

Ala Asn Lys Thr

(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]hexanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Ala Asn Thr Lys

(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]-3-hydroxybutanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Ala Gln Lys Ser

(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-aminopropanamido]-4-carbamoylbutanamido]hexanamido]-3-hydroxypropanoic acid

C17H32N6O7 (432.2332)


   

Ala Gln Ser Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-4-carbamoylbutanamido]-3-hydroxypropanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Ala Ser Lys Gln

(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-hydroxypropanamido]hexanamido]-4-carbamoylbutanoic acid

C17H32N6O7 (432.2332)


   

Ala Ser Gln Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-hydroxypropanamido]-4-carbamoylbutanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Ala Thr Lys Asn

(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-aminopropanamido]-3-hydroxybutanamido]hexanamido]-3-carbamoylpropanoic acid

C17H32N6O7 (432.2332)


   

Ala Thr Asn Lys

(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-aminopropanamido]-3-hydroxybutanamido]-3-carbamoylpropanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Gly Lys Gln Thr

(2S,3R)-2-[(2S)-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]-4-carbamoylbutanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Gly Lys Thr Gln

(2S)-2-[(2S,3R)-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]-3-hydroxybutanamido]-4-carbamoylbutanoic acid

C17H32N6O7 (432.2332)


   

Gly Gln Lys Thr

(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]hexanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Gly Gln Thr Lys

(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]-3-hydroxybutanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Gly Thr Lys Gln

(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-(2-aminoacetamido)-3-hydroxybutanamido]hexanamido]-4-carbamoylbutanoic acid

C17H32N6O7 (432.2332)


   

Gly Thr Gln Lys

(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-(2-aminoacetamido)-3-hydroxybutanamido]-4-carbamoylbutanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Lys Ala Asn Thr

(2S,3R)-2-[(2S)-3-carbamoyl-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]propanamido]propanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Lys Ala Gln Ser

(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]propanamido]butanamido]-3-hydroxypropanoic acid

C17H32N6O7 (432.2332)


   

Lys Ala Ser Gln

(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]propanamido]-3-hydroxypropanamido]butanoic acid

C17H32N6O7 (432.2332)


   

Lys Ala Thr Asn

(2S)-3-carbamoyl-2-[(2S,3R)-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]propanamido]-3-hydroxybutanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Lys Gly Gln Thr

(2S,3R)-2-[(2S)-4-carbamoyl-2-{2-[(2S)-2,6-diaminohexanamido]acetamido}butanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Lys Gly Thr Gln

(2S)-4-carbamoyl-2-[(2S,3R)-2-{2-[(2S)-2,6-diaminohexanamido]acetamido}-3-hydroxybutanamido]butanoic acid

C17H32N6O7 (432.2332)


   

Lys Asn Ala Thr

(2S,3R)-2-[(2S)-2-[(2S)-3-carbamoyl-2-[(2S)-2,6-diaminohexanamido]propanamido]propanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Lys Asn Thr Ala

(2S)-2-[(2S,3R)-2-[(2S)-3-carbamoyl-2-[(2S)-2,6-diaminohexanamido]propanamido]-3-hydroxybutanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Lys Gln Ala Ser

(2S)-2-[(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2,6-diaminohexanamido]butanamido]propanamido]-3-hydroxypropanoic acid

C17H32N6O7 (432.2332)


   

Lys Gln Gly Thr

(2S,3R)-2-{2-[(2S)-4-carbamoyl-2-[(2S)-2,6-diaminohexanamido]butanamido]acetamido}-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Lys Gln Ser Ala

(2S)-2-[(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2,6-diaminohexanamido]butanamido]-3-hydroxypropanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Lys Gln Thr Gly

2-[(2S,3R)-2-[(2S)-4-carbamoyl-2-[(2S)-2,6-diaminohexanamido]butanamido]-3-hydroxybutanamido]acetic acid

C17H32N6O7 (432.2332)


   

Lys Ser Ala Gln

(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxypropanamido]propanamido]butanoic acid

C17H32N6O7 (432.2332)


   

Lys Ser Gln Ala

(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxypropanamido]butanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Lys Thr Ala Asn

(2S)-3-carbamoyl-2-[(2S)-2-[(2S,3R)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxybutanamido]propanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Lys Thr Gly Gln

(2S)-4-carbamoyl-2-{2-[(2S,3R)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxybutanamido]acetamido}butanoic acid

C17H32N6O7 (432.2332)


   

Lys Thr Asn Ala

(2S)-2-[(2S)-3-carbamoyl-2-[(2S,3R)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxybutanamido]propanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Lys Thr Gln Gly

2-[(2S)-4-carbamoyl-2-[(2S,3R)-2-[(2S)-2,6-diaminohexanamido]-3-hydroxybutanamido]butanamido]acetic acid

C17H32N6O7 (432.2332)


   

Asn Ala Lys Thr

(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]hexanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Asn Ala Thr Lys

(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]-3-hydroxybutanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Asn Lys Ala Thr

(2S,3R)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-3-carbamoylpropanamido]hexanamido]propanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Asn Lys Thr Ala

(2S)-2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-amino-3-carbamoylpropanamido]hexanamido]-3-hydroxybutanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Asn Thr Ala Lys

(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxybutanamido]propanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Asn Thr Lys Ala

(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxybutanamido]hexanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Gln Ala Lys Ser

(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]propanamido]hexanamido]-3-hydroxypropanoic acid

C17H32N6O7 (432.2332)


   

Gln Ala Ser Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]propanamido]-3-hydroxypropanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Gln Gly Lys Thr

(2S,3R)-2-[(2S)-6-amino-2-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}hexanamido]-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Gln Gly Thr Lys

(2S)-6-amino-2-[(2S,3R)-2-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}-3-hydroxybutanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Gln Lys Ala Ser

(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-4-carbamoylbutanamido]hexanamido]propanamido]-3-hydroxypropanoic acid

C17H32N6O7 (432.2332)


   

Gln Lys Gly Thr

(2S,3R)-2-{2-[(2S)-6-amino-2-[(2S)-2-amino-4-carbamoylbutanamido]hexanamido]acetamido}-3-hydroxybutanoic acid

C17H32N6O7 (432.2332)


   

Gln Lys Ser Ala

(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-4-carbamoylbutanamido]hexanamido]-3-hydroxypropanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Gln Lys Thr Gly

2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-amino-4-carbamoylbutanamido]hexanamido]-3-hydroxybutanamido]acetic acid

C17H32N6O7 (432.2332)


   

Gln Ser Ala Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxypropanamido]propanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Gln Ser Lys Ala

(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxypropanamido]hexanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Gln Thr Gly Lys

(2S)-6-amino-2-{2-[(2S,3R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxybutanamido]acetamido}hexanoic acid

C17H32N6O7 (432.2332)


   

Gln Thr Lys Gly

2-[(2S)-6-amino-2-[(2S,3R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxybutanamido]hexanamido]acetic acid

C17H32N6O7 (432.2332)


   

Ser Ala Lys Gln

(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]propanamido]hexanamido]-4-carbamoylbutanoic acid

C17H32N6O7 (432.2332)


   

Ser Ala Gln Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]propanamido]-4-carbamoylbutanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Ser Lys Ala Gln

(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-3-hydroxypropanamido]hexanamido]propanamido]-4-carbamoylbutanoic acid

C17H32N6O7 (432.2332)


   

Ser Lys Gln Ala

(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-amino-3-hydroxypropanamido]hexanamido]-4-carbamoylbutanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Ser Gln Ala Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-carbamoylbutanamido]propanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Ser Gln Lys Ala

(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-carbamoylbutanamido]hexanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Thr Ala Lys Asn

(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]propanamido]hexanamido]-3-carbamoylpropanoic acid

C17H32N6O7 (432.2332)


   

Thr Ala Asn Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]propanamido]-3-carbamoylpropanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Thr Gly Lys Gln

(2S)-2-[(2S)-6-amino-2-{2-[(2S,3R)-2-amino-3-hydroxybutanamido]acetamido}hexanamido]-4-carbamoylbutanoic acid

C17H32N6O7 (432.2332)


   

Thr Gly Gln Lys

(2S)-6-amino-2-[(2S)-2-{2-[(2S,3R)-2-amino-3-hydroxybutanamido]acetamido}-4-carbamoylbutanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Thr Lys Ala Asn

(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanamido]propanamido]-3-carbamoylpropanoic acid

C17H32N6O7 (432.2332)


   

Thr Lys Gly Gln

(2S)-2-{2-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanamido]acetamido}-4-carbamoylbutanoic acid

C17H32N6O7 (432.2332)


   

Thr Lys Asn Ala

(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanamido]-3-carbamoylpropanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Thr Lys Gln Gly

2-[(2S)-2-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanamido]-4-carbamoylbutanamido]acetic acid

C17H32N6O7 (432.2332)


   

Thr Asn Ala Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carbamoylpropanamido]propanamido]hexanoic acid

C17H32N6O7 (432.2332)


   

Thr Asn Lys Ala

(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carbamoylpropanamido]hexanamido]propanoic acid

C17H32N6O7 (432.2332)


   

Thr Gln Gly Lys

(2S)-6-amino-2-{2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carbamoylbutanamido]acetamido}hexanoic acid

C17H32N6O7 (432.2332)


   

Thr Gln Lys Gly

2-[(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carbamoylbutanamido]hexanamido]acetic acid

C17H32N6O7 (432.2332)