Exact Mass: 430.2409
Exact Mass Matches: 430.2409
Found 430 metabolites which its exact mass value is equals to given mass value 430.2409
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Budesonide
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D000893 - Anti-Inflammatory Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07E - Intestinal antiinflammatory agents > A07EA - Corticosteroids acting locally R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BA - Glucocorticoids D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii) R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AD - Corticosteroids COVID info from clinicaltrials, clinicaltrial, clinicaltrial, clinicaltrials, clinical trial, clinical trials CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9413; ORIGINAL_PRECURSOR_SCAN_NO 9410 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9427; ORIGINAL_PRECURSOR_SCAN_NO 9425 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9421; ORIGINAL_PRECURSOR_SCAN_NO 9419 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9462; ORIGINAL_PRECURSOR_SCAN_NO 9460 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9470; ORIGINAL_PRECURSOR_SCAN_NO 9465 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9478; ORIGINAL_PRECURSOR_SCAN_NO 9475 CONFIDENCE standard compound; INTERNAL_ID 2822
Trandolapril
C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
Budesonide
Budesonide is only found in individuals that have used or taken this drug. It is a glucocorticoid used in the management of asthma, the treatment of various skin disorders, and allergic rhinitis. [PubChem]The exact mechanism of action of budesonide in the treatment of Crohns disease is not fully understood. However, being a glucocorticosteroid, budesonide has a high local anti-inflammatory effect. A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07E - Intestinal antiinflammatory agents > A07EA - Corticosteroids acting locally R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BA - Glucocorticoids D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii) R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AD - Corticosteroids D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids COVID info from clinicaltrials, clinicaltrial, clinicaltrial, clinicaltrials, clinical trial, clinical trials D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D000893 - Anti-Inflammatory Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Trandolapril
Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Trandolapril may be used to treat mild to moderate hypertension, to improve survival following myocardial infarction in clinically stable patients with left ventricular dysfunction, as an adjunct treatment for congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy. C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
3b,6b-Diangeloyloxy-7(11)-eremophilen-12,8b-olide
3b,6b-Diangeloyloxy-7(11)-eremophilen-12,8b-olide is a constituent of Petasites japonicus (sweet coltsfoot). Constituent of Petasites japonicus (sweet coltsfoot)
Homofukinolide
Constituent of Petasites japonicus (sweet coltsfoot). Homofukinolide is found in giant butterbur and green vegetables. Homofukinolide is found in giant butterbur. Homofukinolide is a constituent of Petasites japonicus (sweet coltsfoot)
Antibiotic CJ 15544
Antibiotic CJ 15544 is found in mushrooms. Antibiotic CJ 15544 is a metabolite of Hericium ramosum. Metabolite of Hericium ramosum. Antibiotic CJ 15544 is found in mushrooms.
Antibiotic CP 412065
Antibiotic CP 412065 is found in mushrooms. Antibiotic CP 412065 is a metabolite of Hericium ramosum. Metabolite of Hericium ramosum. Antibiotic CP 412065 is found in mushrooms.
(22R)-Budesonide
Indolapril
Ingenol mebutate
Nivacortol
Ingenol_mebutate
Ingenol mebutate is a tetracyclic diterpenoid ester obtained by formal condensation of the carboxy group of (2Z)-2-methylbut-2-enoic (angelic) acid with the 3-hydroxy group of ingenol. Used for the topical treatment of actinic keratosis. It has a role as an antineoplastic agent. It is a tetracyclic diterpenoid, a carboxylic ester and a cyclic terpene ketone. It is functionally related to an angelic acid and an ingenol. Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis. Before approval, ingenol mebutate was called PEP005 as an investigational drug. PEP005 is a selective small molecule activator of protein kinase C (PKC) extracted from the plant Euphorbia peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions including warts and cancer. PEP005 also has potent anti-leukemic effects, inducing apoptosis in myeloid leukemia cell lines and primary AML cells at nanomolar concentrations. Ingenol mebutate is a Cell Death Inducer. The physiologic effect of ingenol mebutate is by means of Increased Cellular Death. Ingenol mebutate is a natural product found in Euphorbia peplus with data available. Ingenol Mebutate is a selective small-molecule activator of protein kinase C (PKC) isolated from the plant Euphorbia peplus with potential antineoplastic activity. Ingenol mebutate activates various protein kinase C (PKC) isoforms, thereby inducing apoptosis in some tumor cells, including myeloid leukemia cells, melanoma cells, and basal cell carcinoma cells. The PKC family consists of signaling isoenzymes that regulate many cell processes including proliferation, differentiation, and apoptosis. D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use C274 - Antineoplastic Agent > C129839 - Apoptotic Pathway-targeting Antineoplastic Agent Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
15,16-dehydrosalvileucolide-6,23-lactone-trans-epoxide
3beta-<2-methylbutyryloxy>-6beta-angeloyloxy-10betaH-furoeremophil-9-one
3beta-angeloyloxy-6beta-(3-methylbutanoyloxy)furanoeremophilan-14-al
8,9-Diangeloyl-(8alpha,9beta,10beta)-8,9,10-Trihydroxy-3-longipinen-5-one|8beta,9alpha-Diangeloyloxy-7beta-hydroxy-1-oxo-alpha-longipinen
16beta-Acetoxy-14,15beta-epoxy-3beta-hydroxy-5beta,14beta-card-20(22)-enolid|16beta-Acetoxy-3beta-hydroxy-14,15beta-epoxido-5beta,14beta-card-20(22)-enolid
1alpha,8-bisangeloyloxy-3beta,4beta-epoxy-bisabola-7(14),10-diene
9alpha-hydroxy-6beta-(9-hydroxydeca-2E,4E,6E-trienoyloxy)-5alpha-drim-7-en-11,12-olide|ustusolate B
9alpha-(Angeloyloxy)-7beta-(2-methyl-2,3-epoxybutyryloxy)longipinen-1-on
integric acid
An eremophilane sesquiterpenoid with anti-HIV-1 activity. It is isolated from Xylaria sp. MF6254.
1alpha,8-bissenecioyloxy-3beta,4beta-epoxybisabola-7(14),10-dien-2-one
2-dehydrorastevione|dehydrorastevione|longipin-2-ene-7beta,8alpha,9alpha-triol-1-one 7,8-diangelate
2alpha-hydroxy-17,O-dihydrobrickellidiffusic acid spiro ketal lactone
(17R)-3beta-hydroxy-4beta-acetoxy-8,14beta-epoxy-5alpha-card-20(22)-enolide
abiesadine S|methyl 7-oxo-15-hydroxy-8,11,13-abietatriene-18-succinate
10-(2, 3-Epoxy-2-methylbutanoyl), 9-angeloyl-Cinaglabrone|9-Angeloyl-10(2,3-epoxy-2-methylbutyryl)-cinaglabron|9-Angeloyl-10<2,3-epoxy-2-methylbutyryl>-cinaglabron
1alpha-angeloyloxy-8-senecioyloxy-3beta,4beta-epoxybisabola-7(14),10-dien-2-one
10-Angeloyl-9-(2,3-epoxy-2-methylbutyryl)-cinaglabron|10-Angeloyl-9-<2,3-epoxy-2-methylbutyryl>-cinaglabron|9-(2, 3-Epoxy-2-methylbutanoyl), 10-angeloyl-Cinaglabrone
1alpha-senecioyloxy-8-angeloyloxy-3beta,4beta-epoxybisabola-7(14),10-dien-2-one
Val Ala Ile Glu
C25H34O6_(1S,3R,3aS,4S,8aR)-1-Acetoxy-3-hydroxy-3-isopropyl-6,8a-dimethyl-1,2,3,3a,4,5,8,8a-octahydro-4-azulenyl 4-methoxybenzoate
(2R,2R,4aS,6R,8aS)-7-formyl-4-hydroxy-6-(hydroxymethyl)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydro-2H,3H-spiro[benzofuran-2,1-naphthalen]-6-yl acetate
Ala Asp Ile Ile
Ala Asp Ile Leu
Ala Asp Leu Ile
Ala Asp Leu Leu
Ala Glu Ile Val
Ala Glu Leu Val
Ala Glu Val Ile
Ala Glu Val Leu
Ala Ile Asp Ile
Ala Ile Asp Leu
Ala Ile Glu Val
Ala Ile Ile Asp
Ala Ile Leu Asp
Ala Ile Val Glu
Ala Leu Asp Ile
Ala Leu Asp Leu
Ala Leu Glu Val
Ala Leu Ile Asp
Ala Leu Leu Asp
Ala Leu Val Glu
Ala Val Glu Ile
Ala Val Glu Leu
Ala Val Ile Glu
Ala Val Leu Glu
Asp Ala Ile Ile
Asp Ala Ile Leu
Asp Ala Leu Ile
Asp Ala Leu Leu
Asp Ile Ala Ile
Asp Ile Ala Leu
Asp Ile Ile Ala
Asp Ile Leu Ala
Asp Leu Ala Ile
Asp Leu Ala Leu
Asp Leu Ile Ala
Asp Leu Leu Ala
Asp Val Val Val
Glu Ala Ile Val
Glu Ala Leu Val
Glu Ala Val Ile
Glu Ala Val Leu
Glu Gly Ile Ile
Glu Gly Ile Leu
Glu Gly Leu Ile
Glu Gly Leu Leu
Glu Ile Ala Val
Glu Ile Gly Ile
Glu Ile Gly Leu
Glu Ile Ile Gly
Glu Ile Leu Gly
Glu Ile Val Ala
Glu Leu Ala Val
Glu Leu Gly Ile
Glu Leu Gly Leu
Glu Leu Ile Gly
Glu Leu Leu Gly
Glu Leu Val Ala
Glu Val Ala Ile
Glu Val Ala Leu
Glu Val Ile Ala
Glu Val Leu Ala
Gly Glu Ile Ile
Gly Glu Ile Leu
Gly Glu Leu Ile
Gly Glu Leu Leu
Gly Ile Glu Ile
Gly Ile Glu Leu
Gly Ile Ile Glu
Gly Ile Leu Glu
Gly Leu Glu Ile
Gly Leu Glu Leu
Gly Leu Ile Glu
Gly Leu Leu Glu
Ile Ala Asp Ile
Ile Ala Asp Leu
Ile Ala Glu Val
Ile Ala Ile Asp
Ile Ala Leu Asp
Ile Ala Val Glu
Ile Asp Ala Ile
Ile Asp Ala Leu
Ile Asp Ile Ala
Ile Asp Leu Ala
Ile Glu Ala Val
Ile Glu Gly Ile
Ile Glu Gly Leu
Ile Glu Ile Gly
Ile Glu Leu Gly
Ile Glu Val Ala
Ile Gly Glu Ile
Ile Gly Glu Leu
Ile Gly Ile Glu
Ile Gly Leu Glu
Ile Ile Ala Asp
Ile Ile Asp Ala
Ile Ile Glu Gly
Ile Ile Gly Glu
Ile Leu Ala Asp
Ile Leu Asp Ala
Ile Leu Glu Gly
Ile Leu Gly Glu
Ile Pro Thr Thr
Ile Thr Pro Thr
Ile Thr Thr Pro
Ile Val Ala Glu
Ile Val Glu Ala
Leu Ala Asp Ile
Leu Ala Asp Leu
Leu Ala Glu Val
Leu Ala Ile Asp
Leu Ala Leu Asp
Leu Ala Val Glu
Leu Asp Ala Ile
Leu Asp Ala Leu
Leu Asp Ile Ala
Leu Asp Leu Ala
Leu Glu Ala Val
Leu Glu Gly Ile
Leu Glu Gly Leu
Leu Glu Ile Gly
Leu Glu Leu Gly
Leu Glu Val Ala
Leu Gly Glu Ile
Leu Gly Glu Leu
Leu Gly Ile Glu
Leu Gly Leu Glu
Leu Ile Ala Asp
Leu Ile Asp Ala
Leu Ile Glu Gly
Leu Ile Gly Glu
Leu Leu Ala Asp
Leu Leu Asp Ala
Leu Leu Glu Gly
Leu Leu Gly Glu
Leu Pro Thr Thr
Leu Thr Pro Thr
Leu Thr Thr Pro
Leu Val Ala Glu
Leu Val Glu Ala
Pro Ile Thr Thr
Pro Leu Thr Thr
Pro Thr Ile Thr
Pro Thr Leu Thr
Pro Thr Thr Ile
Pro Thr Thr Leu
Thr Ile Pro Thr
Thr Ile Thr Pro
Thr Leu Pro Thr
Thr Leu Thr Pro
Thr Pro Ile Thr
Thr Pro Leu Thr
Thr Pro Thr Ile
Thr Pro Thr Leu
Thr Thr Ile Pro
Thr Thr Leu Pro
Thr Thr Pro Ile
Thr Thr Pro Leu
Val Ala Glu Ile
Val Ala Glu Leu
Val Ala Leu Glu
Val Asp Val Val
Val Glu Ala Ile
Val Glu Ala Leu
Val Glu Ile Ala
Val Glu Leu Ala
Val Ile Ala Glu
Val Ile Glu Ala
Val Leu Ala Glu
Val Leu Glu Ala
Val Val Asp Val
Val Val Val Asp
AL 6598
Antibiotic CP 412065
Homofukinolide
3b,6b-Diangeloyloxy-7(11)-eremophilen-12,8b-olide
Ingenol Mebutate
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use C274 - Antineoplastic Agent > C129839 - Apoptotic Pathway-targeting Antineoplastic Agent Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
nivacortol
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
(+/-)-4-O-benzyl-1,2:5,6-di-O-cyclohexylidene-myo-inositol
3-O-BENZYL-1,2,5,6-DI-O-CYCLOHEXYLIDENE-α-D-GLUCOFURANOSE
EHop-016
EHop-016 is a potent and selective Rac GTPase Rac1 and Rac3 inhibitor. EHop-016 inhibits Rac1 activity with an IC50 of 1.1 μM in MDA-MB-435 cells. EHop-016 inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration[1][2].
4-O-BENZYL-1,2:5,6-DI-O-CYCLOHEXYLIDENE-L-MYO-INOSITOL
4,4,5,5-tetramethyl-2-[6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anthracen-2-yl]-1,3,2-dioxaborolane
1-[2-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
Diphenylacetylene-4,4-diboronic acid bis(pinacol) ester
3,4-Dihydro-7-(4-(4-(1-naphthyl)piperazino)butoxy)-1,8-naphthyridine-2(1H)-one
Progesterone-11-Alpha-Ol-Hemisuccinate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
5-[10-(5-Methoxy-1,5-dioxopentyl)-1,7-dioxa-4,10-diazacyclododec-4-yl]-5-oxopentanoic acid methyl ester
(2s,3s)-3-Amino-4-[(3s)-3-Fluoropyrrolidin-1-Yl]-N,N-Dimethyl-4-Oxo-2-(Trans-4-[1,2,4]triazolo[1,5-A]pyridin-5-Ylcyclohexyl)butanamide
[5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxo-4-tetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dienyl] (E)-2-methylbut-2-enoate
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use
Ala-Leu-Leu-Asp
A tetrapeptide composed of L-alanine, two L-leucine units, and L-aspartic acid joined in sequence by peptide linkages.
(1S,4R,7S,8aR)-4-{[(2E,4S)-2,4-dimethyloct-2-enoyl]oxy}-8a-methyl-6-oxo-7-(3-oxoprop-1-en-2-yl)-1,2,3,4,6,7,8,8a-octahydronaphthalene-1-carboxylic acid
(2S)-1-[(2R)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-1-oxopropyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
Asp-Val-Val-Val
A tetrapeptide composed of L-aspartic acid and three L-valine units joined in sequence by peptide linkages.
(2S,3aR,5aS,7S,9aR)-1,1,3a,4,5a,7,7-heptamethyl-3,6-dioxo-3,3a,4,5,5a,6,7,8,9,9a-decahydro-1H,3H-spiro[[1]benzofuran-2,6-[2]benzoxepine]-5-carboxylic acid
(1S,2S,4R,6R,8R,9S,11R,12R,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
asnovolin I
A meroterpenoid with formula C25H34O6 isolated from the fungus Aspergillus novofumigatus. It is an intermediate produced in the biosynthetic pathway leading to the synthesis of novofumigatonin.