Chemical Formula: C25H34O6
Chemical Formula C25H34O6
Found 89 metabolite its formula value is C25H34O6
Budesonide
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D000893 - Anti-Inflammatory Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07E - Intestinal antiinflammatory agents > A07EA - Corticosteroids acting locally R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BA - Glucocorticoids D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii) R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AD - Corticosteroids COVID info from clinicaltrials, clinicaltrial, clinicaltrial, clinicaltrials, clinical trial, clinical trials CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9413; ORIGINAL_PRECURSOR_SCAN_NO 9410 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9427; ORIGINAL_PRECURSOR_SCAN_NO 9425 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9421; ORIGINAL_PRECURSOR_SCAN_NO 9419 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9462; ORIGINAL_PRECURSOR_SCAN_NO 9460 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9470; ORIGINAL_PRECURSOR_SCAN_NO 9465 CONFIDENCE standard compound; INTERNAL_ID 1169; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9478; ORIGINAL_PRECURSOR_SCAN_NO 9475 CONFIDENCE standard compound; INTERNAL_ID 2822
Budesonide
Budesonide is only found in individuals that have used or taken this drug. It is a glucocorticoid used in the management of asthma, the treatment of various skin disorders, and allergic rhinitis. [PubChem]The exact mechanism of action of budesonide in the treatment of Crohns disease is not fully understood. However, being a glucocorticosteroid, budesonide has a high local anti-inflammatory effect. A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07E - Intestinal antiinflammatory agents > A07EA - Corticosteroids acting locally R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BA - Glucocorticoids D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii) R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AD - Corticosteroids D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids COVID info from clinicaltrials, clinicaltrial, clinicaltrial, clinicaltrials, clinical trial, clinical trials D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D000893 - Anti-Inflammatory Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
3b,6b-Diangeloyloxy-7(11)-eremophilen-12,8b-olide
3b,6b-Diangeloyloxy-7(11)-eremophilen-12,8b-olide is a constituent of Petasites japonicus (sweet coltsfoot). Constituent of Petasites japonicus (sweet coltsfoot)
Homofukinolide
Constituent of Petasites japonicus (sweet coltsfoot). Homofukinolide is found in giant butterbur and green vegetables. Homofukinolide is found in giant butterbur. Homofukinolide is a constituent of Petasites japonicus (sweet coltsfoot)
Antibiotic CJ 15544
Antibiotic CJ 15544 is found in mushrooms. Antibiotic CJ 15544 is a metabolite of Hericium ramosum. Metabolite of Hericium ramosum. Antibiotic CJ 15544 is found in mushrooms.
Antibiotic CP 412065
Antibiotic CP 412065 is found in mushrooms. Antibiotic CP 412065 is a metabolite of Hericium ramosum. Metabolite of Hericium ramosum. Antibiotic CP 412065 is found in mushrooms.
(22R)-Budesonide
Ingenol mebutate
Ingenol_mebutate
Ingenol mebutate is a tetracyclic diterpenoid ester obtained by formal condensation of the carboxy group of (2Z)-2-methylbut-2-enoic (angelic) acid with the 3-hydroxy group of ingenol. Used for the topical treatment of actinic keratosis. It has a role as an antineoplastic agent. It is a tetracyclic diterpenoid, a carboxylic ester and a cyclic terpene ketone. It is functionally related to an angelic acid and an ingenol. Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis. Before approval, ingenol mebutate was called PEP005 as an investigational drug. PEP005 is a selective small molecule activator of protein kinase C (PKC) extracted from the plant Euphorbia peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions including warts and cancer. PEP005 also has potent anti-leukemic effects, inducing apoptosis in myeloid leukemia cell lines and primary AML cells at nanomolar concentrations. Ingenol mebutate is a Cell Death Inducer. The physiologic effect of ingenol mebutate is by means of Increased Cellular Death. Ingenol mebutate is a natural product found in Euphorbia peplus with data available. Ingenol Mebutate is a selective small-molecule activator of protein kinase C (PKC) isolated from the plant Euphorbia peplus with potential antineoplastic activity. Ingenol mebutate activates various protein kinase C (PKC) isoforms, thereby inducing apoptosis in some tumor cells, including myeloid leukemia cells, melanoma cells, and basal cell carcinoma cells. The PKC family consists of signaling isoenzymes that regulate many cell processes including proliferation, differentiation, and apoptosis. D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use C274 - Antineoplastic Agent > C129839 - Apoptotic Pathway-targeting Antineoplastic Agent Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
15,16-dehydrosalvileucolide-6,23-lactone-trans-epoxide
3beta-<2-methylbutyryloxy>-6beta-angeloyloxy-10betaH-furoeremophil-9-one
3beta-angeloyloxy-6beta-(3-methylbutanoyloxy)furanoeremophilan-14-al
8,9-Diangeloyl-(8alpha,9beta,10beta)-8,9,10-Trihydroxy-3-longipinen-5-one|8beta,9alpha-Diangeloyloxy-7beta-hydroxy-1-oxo-alpha-longipinen
16beta-Acetoxy-14,15beta-epoxy-3beta-hydroxy-5beta,14beta-card-20(22)-enolid|16beta-Acetoxy-3beta-hydroxy-14,15beta-epoxido-5beta,14beta-card-20(22)-enolid
1alpha,8-bisangeloyloxy-3beta,4beta-epoxy-bisabola-7(14),10-diene
9alpha-hydroxy-6beta-(9-hydroxydeca-2E,4E,6E-trienoyloxy)-5alpha-drim-7-en-11,12-olide|ustusolate B
9alpha-(Angeloyloxy)-7beta-(2-methyl-2,3-epoxybutyryloxy)longipinen-1-on
integric acid
An eremophilane sesquiterpenoid with anti-HIV-1 activity. It is isolated from Xylaria sp. MF6254.
1alpha,8-bissenecioyloxy-3beta,4beta-epoxybisabola-7(14),10-dien-2-one
2-dehydrorastevione|dehydrorastevione|longipin-2-ene-7beta,8alpha,9alpha-triol-1-one 7,8-diangelate
2alpha-hydroxy-17,O-dihydrobrickellidiffusic acid spiro ketal lactone
(17R)-3beta-hydroxy-4beta-acetoxy-8,14beta-epoxy-5alpha-card-20(22)-enolide
abiesadine S|methyl 7-oxo-15-hydroxy-8,11,13-abietatriene-18-succinate
10-(2, 3-Epoxy-2-methylbutanoyl), 9-angeloyl-Cinaglabrone|9-Angeloyl-10(2,3-epoxy-2-methylbutyryl)-cinaglabron|9-Angeloyl-10<2,3-epoxy-2-methylbutyryl>-cinaglabron
1alpha-angeloyloxy-8-senecioyloxy-3beta,4beta-epoxybisabola-7(14),10-dien-2-one
10-Angeloyl-9-(2,3-epoxy-2-methylbutyryl)-cinaglabron|10-Angeloyl-9-<2,3-epoxy-2-methylbutyryl>-cinaglabron|9-(2, 3-Epoxy-2-methylbutanoyl), 10-angeloyl-Cinaglabrone
1alpha-senecioyloxy-8-angeloyloxy-3beta,4beta-epoxybisabola-7(14),10-dien-2-one
C25H34O6_(1S,3R,3aS,4S,8aR)-1-Acetoxy-3-hydroxy-3-isopropyl-6,8a-dimethyl-1,2,3,3a,4,5,8,8a-octahydro-4-azulenyl 4-methoxybenzoate
(2R,2R,4aS,6R,8aS)-7-formyl-4-hydroxy-6-(hydroxymethyl)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydro-2H,3H-spiro[benzofuran-2,1-naphthalen]-6-yl acetate
CJ 15544
Antibiotic CP 412065
Homofukinolide
3b,6b-Diangeloyloxy-7(11)-eremophilen-12,8b-olide
Ingenol Mebutate
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use C274 - Antineoplastic Agent > C129839 - Apoptotic Pathway-targeting Antineoplastic Agent Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
(+/-)-4-O-benzyl-1,2:5,6-di-O-cyclohexylidene-myo-inositol
3-O-BENZYL-1,2,5,6-DI-O-CYCLOHEXYLIDENE-α-D-GLUCOFURANOSE
4-O-BENZYL-1,2:5,6-DI-O-CYCLOHEXYLIDENE-L-MYO-INOSITOL
Progesterone-11-Alpha-Ol-Hemisuccinate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
[5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxo-4-tetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dienyl] (E)-2-methylbut-2-enoate
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use
(1S,4R,7S,8aR)-4-{[(2E,4S)-2,4-dimethyloct-2-enoyl]oxy}-8a-methyl-6-oxo-7-(3-oxoprop-1-en-2-yl)-1,2,3,4,6,7,8,8a-octahydronaphthalene-1-carboxylic acid
(2S,3aR,5aS,7S,9aR)-1,1,3a,4,5a,7,7-heptamethyl-3,6-dioxo-3,3a,4,5,5a,6,7,8,9,9a-decahydro-1H,3H-spiro[[1]benzofuran-2,6-[2]benzoxepine]-5-carboxylic acid
(1S,2S,4R,6R,8R,9S,11R,12R,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
asnovolin I
A meroterpenoid with formula C25H34O6 isolated from the fungus Aspergillus novofumigatus. It is an intermediate produced in the biosynthetic pathway leading to the synthesis of novofumigatonin.