Exact Mass: 425.1829718000001
Exact Mass Matches: 425.1829718000001
Found 399 metabolites which its exact mass value is equals to given mass value 425.1829718000001,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
domperidone
A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03F - Propulsives > A03FA - Propulsives D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics D002491 - Central Nervous System Agents CONFIDENCE standard compound; INTERNAL_ID 2739 CONFIDENCE standard compound; INTERNAL_ID 8517 Domperidone (R33812) is an orally active and selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine[1].
Domperidone
Domperidone is only found in individuals that have used or taken this drug. It is a specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms. [PubChem]Domperidone acts as a gastrointestinal emptying (delayed) adjunct and peristaltic stimulant. The gastroprokinetic properties of domperidone are related to its peripheral dopamine receptor blocking properties. Domperidone facilitates gastric emptying and decreases small bowel transit time by increasing esophageal and gastric peristalsis and by lowering esophageal sphincter pressure. Antiemetic: The antiemetic properties of domperidone are related to its dopamine receptor blocking activity at both the chemoreceptor trigger zone and at the gastric level. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03F - Propulsives > A03FA - Propulsives D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics D002491 - Central Nervous System Agents Domperidone (R33812) is an orally active and selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine[1].
O-Desmethyltramadol glucuronide
O-Desmethyltramadol glucuronide is a metabolite of tramadol. Tramadol hydrochloride (trademarked as Conzip, Ryzolt, Ultracet, Ultram in the USA; Ralivia and Zytram XL in Canada) is a centrally-acting synthetic analgesic used to treat moderate to moderately-severe pain. The drug has a wide range of applications, including treatment of rheumatoid arthritis, restless legs syndrome, and fibromyalgia. It was launched and marketed as Tramal by the German pharmaceutical company Grnenthal GmbH in 1977 (Wikipedia).
M2 di-hydroxylated metabolite
M2 di-hydroxylated metabolite is a metabolite of saquinavir. Saquinavir is an antiretroviral drug used in HIV therapy. It falls in the protease inhibitor class. Two formulations have been marketed: a hard-gel capsule formulation of the mesylate, with trade name Invirase, which requires combination with ritonavir to increase the saquinavir bioavailability; a soft-gel capsule formulation of saquinavir, with trade name Fortovase. Both formulations are generally used as a component of highly active antiretroviral therapy (HAART). (Wikipedia)
N,O-Didesmethylvenlafaxine glucuronide
N,O-Didesmethylvenlafaxine glucuronide is a metabolite of venlafaxine (brand name: Effexor or Efexor). Venlafaxine is a bicyclic antidepressant and is usually categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI), but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse.
4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol
(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
C21H27N7O3 (425.21752720000006)
4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1,4-dihydropyrrolo[3,4-d]pyrazol-5-yl]benzoic acid
C25H19N3O4 (425.13754940000007)
Filgotinib
C21H23N5O3S (425.15215280000007)
L - Antineoplastic and immunomodulating agents > L04 - Immunosuppressants > L04A - Immunosuppressants > L04AA - Selective immunosuppressants C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
Guanidine, N-((2S,3S,4R)-6-amino-2-(dimethoxymethyl)-3,4-dihydro-3-hydroxy-2-methyl-2H-1-benzopyran-4-yl)-N'-cyano-N'-(phenylmethyl)-
C22H27N5O4 (425.20629420000006)
Losoxantrone
C22H27N5O4 (425.20629420000006)
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D000970 - Antineoplastic Agents
Mecinarone
C24H27NO6 (425.18382820000005)
Revexepride
C21H32ClN3O4 (425.20812220000005)
Skepinone-L
2-(4,6-diphenyl-1,3,5-triazin-2-yl)-5-(hexyloxy)phenol
3alpha,6beta-bis(4-methoxybenzoyloxy)tropane|merredissine
C24H27NO6 (425.18382820000005)
Alfuzosin hydrochloride (Uroxatral)
C19H28ClN5O4 (425.1829718000001)
(S)-N-[[3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide
C22H20FN3O5 (425.13869220000004)
Ala Ala His Gln
Ala Ala Gln His
Ala His Ala Gln
Ala His Gln Ala
Ala Gln Ala His
Ala Gln His Ala
Gly Gly His Arg
Gly Gly Arg His
Gly His Gly Arg
Gly His Asn Val
Gly His Arg Gly
Gly His Val Asn
Gly Asn His Val
Gly Asn Val His
Gly Arg Gly His
Gly Arg His Gly
Gly Val His Asn
Gly Val Asn His
His Ala Ala Gln
His Ala Gln Ala
His Gly Gly Arg
His Gly Asn Val
His Gly Arg Gly
His Gly Val Asn
His Asn Gly Val
His Asn Val Gly
His Gln Ala Ala
His Arg Gly Gly
His Val Gly Asn
His Val Asn Gly
desmethylnortriptyline glucuronide
C24H27NO6 (425.18382820000005)
Asn Gly His Val
Asn Gly Val His
Asn His Gly Val
Asn His Val Gly
Asn Pro Pro Val
Asn Pro Val Pro
Asn Val Gly His
Asn Val His Gly
Asn Val Pro Pro
Pro Asn Pro Val
Pro Asn Val Pro
Pro Pro Asn Val
Pro Pro Val Asn
Pro Val Asn Pro
Pro Val Pro Asn
Gln Ala Ala His
Gln Ala His Ala
Gln His Ala Ala
Arg Gly Gly His
Arg Gly His Gly
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Divaleroylphosphatidylcholine
C18H36NO8P (425.21784260000004)
PC(5:0/5:0)[U]
C18H36NO8P (425.21784260000004)
2-(4,6-Diphenyl-1,3,5-triazin-2-yl)-5-[(hexyl)oxy]-phenol
N-{2-[(E)-(2-Cyano-4,6-dinitrophenyl)diazenyl]-5-(diethylamino)ph enyl}acetamide
(S)-BnCH2-PyBox, (S,S)-2,6-Bis(4-benzylmethyl-2-oxazolin-2-yl)pyridine
GSK690693
C21H27N7O3 (425.21752720000006)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C61074 - Serine/Threonine Kinase Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor > C155764 - AKT Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation[1][2][3]. GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation[1][2][3].
(S)-2-((TERT-BUTOXYCARBONYL)AMINO)-6-((((4-NITROBENZYL)OXY)CARBONYL)AMINO)HEXANOIC ACID
1,3-Benzodioxole-5-carboxamide, N-(((2-(1-(phenylmethyl)-4-piperdinyl) ethyl)amino)thioxomethyl)-
C23H27N3O3S (425.1773032000001)
z-l-phenylalanine 2-naphthyl ester
C27H23NO4 (425.16269980000004)
Benzyl 4,5-bis(benzyloxy)picolinate
C27H23NO4 (425.16269980000004)
(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
C23H27N3O3S (425.1773032000001)
2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethyl Acetate
C23H27N3O3S (425.1773032000001)
Fmoc-N-(tert-butyloxycarbonylethyl)-glycine
C24H27NO6 (425.18382820000005)
PF-04691502
C22H27N5O4 (425.20629420000006)
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor
Alfuzosin hydrochloride
C19H28ClN5O4 (425.1829718000001)
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D000089162 - Genitourinary Agents > D064804 - Urological Agents Alfuzosin (SL 77499-10) hydrochloride is an orally active, selective and competitive α1-adrenoceptor antagonist. Alfuzosin hydrochloride relaxes the muscles of the prostate and bladder neck, aiding in urination. Alfuzosin hydrochloride can be used in study of benign prostatic hyperplasia (BPH)[1][2].
N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)amino]propyl]-N-methyloxolane-2-carboxamide,hydrochloride
C19H28ClN5O4 (425.1829718000001)
Ethyl-2-ethoxy-1-[[(2-cyanobiphenyl-4-yl)methyl]benzimidazole]-7-carboxylate
Fananserin
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C66885 - Serotonin Antagonist Fananserin (RP 62203) is an orally bioavailable, potent and selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist, with a Ki of 0.37 nM for the rat 5-HT2A receptor. Fananserin also is a selective dopamine D4 receptor antagonist, with a Ki of 2.93 nM for the human dopamine D4 receptor[1].
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-aspartic acid 4-(1,1-dimethylethyl) ester
C24H27NO6 (425.18382820000005)
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid
C24H27NO6 (425.18382820000005)
GlutaMic acid, N-[[(4-Methoxyphenyl)thio]carbonyl]-, bis(1,1-diMethylethyl) ester
C21H31NO6S (425.18719860000004)
bis-(2,2,6,6-Tetramethyl-3,5-heptanedionato)cobalt(II)
5-[1-(3,4-Dimethoxy-benzoyl)-1,2,3,4-tetrahydro-quinolin-6-YL]-6-methyl-3,6-dihydro-[1,3,4]thiadiazin-2-one
C22H23N3O4S (425.14091980000006)
Reproterol hydrochloride
C18H24ClN5O5 (425.14658840000004)
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent > C319 - Bronchodilator C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
Deudomperidone
C78272 - Agent Affecting Nervous System > C66883 - Dopamine Antagonist
Platencin
C24H27NO6 (425.18382820000005)
A monocarboxylic acid amide obtained by the formal condensation of the amino group of 3-amino-2,4-dihydroxybenzoic acid with the carboxy group of the polycyclic cage component. It is an antibiotic isolated from Streptomyces platensis and exhibits inhibitory activity against fatty acid synthase.
N-(1-((5-Cyanopyridin-2-yl)methyl)-1H-pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)acetamide
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators
(R)-2,3-Bis(pentanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
C18H36NO8P (425.21784260000004)
1-[2-[[(3-Chloro-4-methoxyanilino)-oxomethyl]amino]-2-methyl-1-oxopropyl]-4-piperidinecarboxylic acid ethyl ester
C20H28ClN3O5 (425.17173880000007)
Filgotinib
C21H23N5O3S (425.15215280000007)
L - Antineoplastic and immunomodulating agents > L04 - Immunosuppressants > L04A - Immunosuppressants > L04AA - Selective immunosuppressants C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol
C21H27N7O3 (425.21752720000006)
Guanidine, N-((2S,3S,4R)-6-amino-2-(dimethoxymethyl)-3,4-dihydro-3-hydroxy-2-methyl-2H-1-benzopyran-4-yl)-N'-cyano-N'-(phenylmethyl)-
C22H27N5O4 (425.20629420000006)
(2S,4R)-N-[2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidin-1-ium-2-carboxamide
(Z)-1-[6-[2-(dimethylamino)ethoxy]-4,7-dimethoxy-1-benzofuran-5-yl]-3-(4-methoxyphenyl)prop-2-en-1-one
C24H27NO6 (425.18382820000005)
ALIMTA
C20H19N5O6-2 (425.13352740000005)
D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D004791 - Enzyme Inhibitors > D005493 - Folic Acid Antagonists D000970 - Antineoplastic Agents
4-[(2E)-2-{2-[6-hydroxy-3-methyl-2-oxo-8-(piperidin-1-yl)-2,3-dihydro-7H-purin-7-yl]ethylidene}hydrazinyl]benzoic acid
C20H23N7O4 (425.18114380000003)
5-[[(1,5-Dimethyl-3-oxo-2-phenyl-4-pyrazolyl)amino]methylidene]-1-hexyl-1,3-diazinane-2,4,6-trione
C22H27N5O4 (425.20629420000006)
6-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-ethyl-N-phenyl-3-pyridinesulfonamide
C22H23N3O4S (425.14091980000006)
4-(1H-benzimidazol-2-ylthio)-1-[4-(4-nitrophenyl)-1-piperazinyl]-1-butanone
C21H23N5O3S (425.15215280000007)
N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(thiophen-2-ylmethyl)-2-pyridinecarboxamide
5-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-4-triazolecarboxamide
l-Tyrosyl-l-prolyl-l-phenylalanine
C23H27N3O5 (425.19506120000005)
[2-[4-[4-(2-Methylbutan-2-yl)phenoxy]anilino]-2-oxoethyl] 2,3-dihydro-1,4-dioxine-5-carboxylate
C24H27NO6 (425.18382820000005)
1-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-(2-furanylmethyl)-3-(2-oxolanylmethyl)thiourea
C23H27N3O3S (425.1773032000001)
1-[3-[(6-Methoxy-2-naphthalenyl)-oxomethyl]-1-piperidinyl]-2-[(5-methyl-1,3,4-oxadiazol-2-yl)thio]ethanone
C22H23N3O4S (425.14091980000006)
1-Heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine
C18H36NO8P (425.21784260000004)
3-[(2E)-2-[[3-Ethoxy-4-(2-oxo-2-piperidin-1-ylethoxy)phenyl]methylidene]hydrazinyl]benzoic acid
C23H27N3O5 (425.19506120000005)
N-[(E)-2,3-dihydro-1,4-benzodioxin-6-ylmethylideneamino]-N-(2-hydroxyphenyl)octanediamide
C23H27N3O5 (425.19506120000005)
(2R)-3-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl heptanoate
C18H36NO8P (425.21784260000004)
N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide;hydron;chloride
C19H28ClN5O4 (425.1829718000001)
4-fluoro-N-[(2S,3S,6S)-2-(hydroxymethyl)-6-[2-[4-(2-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
4-fluoro-N-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-[4-(2-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
4-[4-[(1S,5R)-3-[(3,5-dimethoxyphenyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzonitrile
2-fluoro-N-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-[4-(3-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
2-fluoro-N-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-[4-(3-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
2-fluoro-N-[(2S,3S,6S)-2-(hydroxymethyl)-6-[2-[4-(3-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
4-fluoro-N-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-[4-(2-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
4-fluoro-N-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-[4-(2-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
4-fluoro-N-[(2S,3S,6R)-2-(hydroxymethyl)-6-[2-[4-(2-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
4-fluoro-N-[(2R,3R,6S)-2-(hydroxymethyl)-6-[2-[4-(2-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
(1R,5S)-N-(2-methoxyphenyl)-7-[4-[(E)-2-phenylethenyl]phenyl]-3,6-diazabicyclo[3.1.1]heptane-3-carboxamide
(2R,3S,4R)-3-[4-[2-(4-fluorophenyl)ethynyl]phenyl]-4-(hydroxymethyl)-1-(1-oxo-2-pyridin-4-ylethyl)-2-azetidinecarbonitrile
(2S,3S,3aR,9bR)-3-(hydroxymethyl)-7-(4-methoxyphenyl)-2-[4-morpholinyl(oxo)methyl]-1,2,3,3a,4,9b-hexahydropyrrolo[2,3-a]indolizin-6-one
C23H27N3O5 (425.19506120000005)
(2R,3R,3aS,9bS)-3-(hydroxymethyl)-7-(4-methoxyphenyl)-2-(morpholine-4-carbonyl)-1,2,3,3a,4,9b-hexahydropyrrolo[2,3-a]indolizin-6-one
C23H27N3O5 (425.19506120000005)
(2R,3R,3aS,9bS)-N-cyclohexyl-7-(3-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1,2,3,3a,4,9b-hexahydropyrrolo[2,3-a]indolizine-2-carboxamide
N-[(2S,3R)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-phenylacetamide
C24H31N3O4 (425.23144460000003)
N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-phenylacetamide
C24H31N3O4 (425.23144460000003)
2-fluoro-N-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-[4-(3-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
2-fluoro-N-[(2S,3S,6R)-2-(hydroxymethyl)-6-[2-[4-(3-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
2-[(1S,3S,4aR,9aS)-1-(hydroxymethyl)-6-[(1-oxo-2-pyridin-4-ylethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N,N-dimethylacetamide
C23H27N3O5 (425.19506120000005)
(2S,3S,3aR,9bR)-N-cyclohexyl-7-(3-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1,2,3,3a,4,9b-hexahydropyrrolo[2,3-a]indolizine-2-carboxamide
1-[(1S)-1-[cyclopropyl(oxo)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-2-spiro[1,3-dihydropyrido[3,4-b]indole-4,3-azetidine]yl]-1-butanone
C24H31N3O4 (425.23144460000003)
(6S,7R,8R)-8-(hydroxymethyl)-4-[2-(4-morpholinyl)-1-oxoethyl]-7-(4-pent-1-ynylphenyl)-1,4-diazabicyclo[4.2.0]octan-2-one
C24H31N3O4 (425.23144460000003)
(6R,7R,8R)-8-(hydroxymethyl)-4-[2-(4-morpholinyl)-1-oxoethyl]-7-(4-pent-1-ynylphenyl)-1,4-diazabicyclo[4.2.0]octan-2-one
C24H31N3O4 (425.23144460000003)
(6S,7S,8S)-8-(hydroxymethyl)-4-[2-(4-morpholinyl)-1-oxoethyl]-7-(4-pent-1-ynylphenyl)-1,4-diazabicyclo[4.2.0]octan-2-one
C24H31N3O4 (425.23144460000003)
(6R,7S,8R)-8-(hydroxymethyl)-4-[2-(4-morpholinyl)-1-oxoethyl]-7-(4-pent-1-ynylphenyl)-1,4-diazabicyclo[4.2.0]octan-2-one
C24H31N3O4 (425.23144460000003)
N-[(2R,3S)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-phenylacetamide
C24H31N3O4 (425.23144460000003)
N-[(2S,3S)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-phenylacetamide
C24H31N3O4 (425.23144460000003)
2-fluoro-N-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-[4-(3-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
2-fluoro-N-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-[4-(3-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
2-fluoro-N-[(2R,3R,6S)-2-(hydroxymethyl)-6-[2-[4-(3-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
4-fluoro-N-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-[4-(2-pyridinyl)-1-triazolyl]ethyl]-3-oxanyl]benzamide
C22H24FN5O3 (425.18630859999996)
2-[(1R,3R,4aS,9aR)-1-(hydroxymethyl)-6-[(1-oxo-2-pyridin-4-ylethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N,N-dimethylacetamide
C23H27N3O5 (425.19506120000005)
3-[4-[(8R,9R,10R)-10-(hydroxymethyl)-6-methylsulfonyl-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]benzonitrile
C23H27N3O3S (425.1773032000001)
1-[(1R)-1-[cyclopropyl(oxo)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-2-spiro[1,3-dihydropyrido[3,4-b]indole-4,3-azetidine]yl]-1-butanone
C24H31N3O4 (425.23144460000003)
(6S,7R,8S)-8-(hydroxymethyl)-4-[2-(4-morpholinyl)-1-oxoethyl]-7-(4-pent-1-ynylphenyl)-1,4-diazabicyclo[4.2.0]octan-2-one
C24H31N3O4 (425.23144460000003)
(6S,7S,8R)-8-(hydroxymethyl)-4-[2-(4-morpholinyl)-1-oxoethyl]-7-(4-pent-1-ynylphenyl)-1,4-diazabicyclo[4.2.0]octan-2-one
C24H31N3O4 (425.23144460000003)
(6R,7R,8S)-8-(hydroxymethyl)-4-[2-(4-morpholinyl)-1-oxoethyl]-7-(4-pent-1-ynylphenyl)-1,4-diazabicyclo[4.2.0]octan-2-one
C24H31N3O4 (425.23144460000003)
(6R,7S,8S)-8-(hydroxymethyl)-4-[2-(4-morpholinyl)-1-oxoethyl]-7-(4-pent-1-ynylphenyl)-1,4-diazabicyclo[4.2.0]octan-2-one
C24H31N3O4 (425.23144460000003)
9-benzyl-2-butyl-1-(2-chlorophenyl)-9H-beta-carbolin-2-ium
C28H26ClN2+ (425.17844060000004)
N-[(Z)-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enylidene]amino]-N-(2-hydroxyphenyl)heptanediamide
C23H27N3O5 (425.19506120000005)
(R)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide
C22H20FN3O5 (425.13869220000004)
2,3-Di(pentanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
C18H36NO8P (425.21784260000004)
(2-Heptanoyloxy-3-propanoyloxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
C18H36NO8P (425.21784260000004)
[1-[2-Aminoethoxy(hydroxy)phosphoryl]oxy-3-hexanoyloxypropan-2-yl] heptanoate
C18H36NO8P (425.21784260000004)
[1-[2-Aminoethoxy(hydroxy)phosphoryl]oxy-3-pentanoyloxypropan-2-yl] octanoate
C18H36NO8P (425.21784260000004)
[1-[2-Aminoethoxy(hydroxy)phosphoryl]oxy-3-butanoyloxypropan-2-yl] nonanoate
C18H36NO8P (425.21784260000004)
[1-Acetyloxy-3-[2-aminoethoxy(hydroxy)phosphoryl]oxypropan-2-yl] undecanoate
C18H36NO8P (425.21784260000004)
(3-Butanoyloxy-2-hexanoyloxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
C18H36NO8P (425.21784260000004)
[1-[2-Aminoethoxy(hydroxy)phosphoryl]oxy-3-propanoyloxypropan-2-yl] decanoate
C18H36NO8P (425.21784260000004)
(3-Acetyloxy-2-octanoyloxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
C18H36NO8P (425.21784260000004)
4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(3-piperidinylmethoxy)-4-imidazo[4,5-c]pyridinyl]-2-methyl-3-butyn-2-ol
C21H27N7O3 (425.21752720000006)
2-[1-[1-[2-(2-luorophenyl)ethyl]piperidin-4-yl]-4-hydroxyindol-6-yl]-2-hydroxy-N-methylacetamide
phosphatidylcholine 10:0
C18H36NO8P (425.21784260000004)
A 1,2-diacyl-sn-glycero-3-phosphocholine in which the two acyl groups contain a total of 10 carbons and no double bonds.
H-Val-Pro-Pro-OH (TFA)
H-Val-Pro-Pro-OH (TFA), a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM.
(3z,6s)-3-({7-[(2s)-2,3-dihydroxy-3-methylbutyl]-2-(2-methylbut-3-en-2-yl)-1h-indol-3-yl}methylidene)-6-methyl-6h-pyrazine-2,5-diol
C24H31N3O4 (425.23144460000003)
n-[(2r,3s,4as,8r,8ar)-8-chloro-2,4a-dihydroxy-8a-methyl-5-oxo-2,3,4,8-tetrahydro-1-benzopyran-3-yl]dodeca-2,10-dienimidic acid
C22H32ClNO5 (425.19688920000004)
1-hydroxy-2,7-dimethoxy-12-(2-methylprop-1-en-1-yl)-10,13,19-triazapentacyclo[11.7.0.0³,¹¹.0⁴,⁹.0¹⁵,¹⁹]icosa-3(11),4,6,8-tetraene-14,20-dione
C23H27N3O5 (425.19506120000005)
2-[(2-{[(1,3-dimethyl-2,4-dioxopteridin-6-yl)(hydroxy)methylidene]amino}-1-hydroxypropylidene)amino]benzenecarboximidic acid
n-[1-({4-chloro-6,6,9a-trimethyl-3-oxo-1h,4h,5h,5ah,7h,8h,9h-naphtho[1,2-c]furan-9-yl}oxy)-3-methyl-1-oxobutan-2-yl]ethanimidic acid
C22H32ClNO5 (425.19688920000004)
3-[2-(hydroxymethyl)-3-methoxyphenyl]-2-(3-methoxyphenyl)-10-methyl-2-azatricyclo[6.3.1.0⁴,¹²]dodeca-1(11),3,6,8(12),9-pentaen-5-one
C27H23NO4 (425.16269980000004)
(2s)-2-[(9ar)-3-hexanoyl-9a-methyl-2,9-dioxo-6-[(1e)-prop-1-en-1-yl]furo[3,2-g]isoquinolin-7-yl]propanoic acid
C24H27NO6 (425.18382820000005)
(2s,2'r,5r,5's,6's,8's)-5',6'-dihydroxy-n,4,4,5,10'-pentamethyl-3,12'-dioxo-11'-sulfanylidene-1',10'-diazaspiro[oxolane-2,4'-tricyclo[6.4.0.0²,⁶]dodecane]-8'-carboximidic acid
4-ethyl-7-hydroxy-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-5-yl acetate
3-{[7-(2,3-dihydroxy-3-methylbutyl)-2-(2-methylbut-3-en-2-yl)-1h-indol-3-yl]methylidene}-5-hydroxy-6-methyl-1,6-dihydropyrazin-2-one
C24H31N3O4 (425.23144460000003)
(1r,2r,12r,15s)-1-hydroxy-2,7-dimethoxy-12-(2-methylprop-1-en-1-yl)-10,13,19-triazapentacyclo[11.7.0.0³,¹¹.0⁴,⁹.0¹⁵,¹⁹]icosa-3(11),4,6,8-tetraene-14,20-dione
C23H27N3O5 (425.19506120000005)
5',6'-dihydroxy-n,4,4,5,10'-pentamethyl-3,12'-dioxo-11'-sulfanylidene-1',10'-diazaspiro[oxolane-2,4'-tricyclo[6.4.0.0²,⁶]dodecane]-8'-carboximidic acid
(20s,21s)-21-hydroxy-5,6,10,11-tetramethoxy-16-azapentacyclo[12.7.0.0²,⁷.0⁸,¹³.0¹⁶,²⁰]henicosa-1(14),2(7),3,5,8(13),9,11-heptaen-16-ium-16-olate
C24H27NO6 (425.18382820000005)
3-(4-hydroxyphenyl)-6-(2-methylpropyl)-4-phenyl-7-oxa-2-azatricyclo[7.4.0.0²,⁶]trideca-1(13),3,9,11-tetraene-5,8-dione
C27H23NO4 (425.16269980000004)
2-[3-hexanoyl-9a-methyl-2,9-dioxo-6-(prop-1-en-1-yl)furo[3,2-g]isoquinolin-7-yl]propanoic acid
C24H27NO6 (425.18382820000005)
(4r)-4-[(1r,4z,8z,10s,13r,15r)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-3-(hydroxymethyl)-1,3-thiazolidin-2-one
C21H31NO6S (425.18719860000004)
3-(2,6-dimethyl-1,2,4a,5,8,8a-hexahydronaphthalene-1-carbonyl)-1,4-dihydroxy-5-{2-hydroxy-7-oxabicyclo[4.1.0]hept-2-en-3-yl}pyridin-2-one
C24H27NO6 (425.18382820000005)
2,4-dihydroxy-3-({1-hydroxy-3-[(1s,5s,8s)-5-methyl-9-methylidene-4-oxotricyclo[6.2.2.0¹,⁶]dodec-2-en-5-yl]propylidene}amino)benzoic acid
C24H27NO6 (425.18382820000005)
(1s,2s,12s,15s)-1-hydroxy-2,7-dimethoxy-12-(2-methylprop-1-en-1-yl)-10,13,19-triazapentacyclo[11.7.0.0³,¹¹.0⁴,⁹.0¹⁵,¹⁹]icosa-3(11),4,6,8-tetraene-14,20-dione
C23H27N3O5 (425.19506120000005)
2-{[(2s)-2-{[(1,3-dimethyl-2,4-dioxopteridin-6-yl)(hydroxy)methylidene]amino}-1-hydroxypropylidene]amino}benzenecarboximidic acid
2,4-dihydroxy-3-({1-hydroxy-3-[(1s,5s,6r,8s)-5-methyl-9-methylidene-4-oxotricyclo[6.2.2.0¹,⁶]dodec-2-en-5-yl]propylidene}amino)benzoic acid
C24H27NO6 (425.18382820000005)
(4e)-3-({[(1s)-2-carboxy-1-[(2-hydroxy-4,5,6,7-tetrahydro-3h-azepin-3-yl)-c-hydroxycarbonimidoyl]ethyl]-c-hydroxycarbonimidoyl}methyl)oct-4-enoic acid
(1s,14s,17r,22r)-10,11-dihydroxy-14,18,18,22-tetramethyl-13-oxa-8-azapentacyclo[12.8.0.0³,¹².0⁴,⁹.0¹⁷,²²]docosa-3(12),4,6,8,10-pentaene-7-carboxylic acid
11-({1,5,7-trihydroxy-10-oxo-3-oxatricyclo[4.3.1.0²,⁴]decan-8-yl}-c-hydroxycarbonimidoyl)undec-10-enoic acid
(1r,2s,12r,15r)-1-hydroxy-2,7-dimethoxy-12-(2-methylprop-1-en-1-yl)-10,13,19-triazapentacyclo[11.7.0.0³,¹¹.0⁴,⁹.0¹⁵,¹⁹]icosa-3(11),4,6,8-tetraene-14,20-dione
C23H27N3O5 (425.19506120000005)
methyl (1r,5s,6r,9r,10s,20r)-9-[(acetyloxy)methyl]-20-hydroxy-5-methyl-3-azahexacyclo[11.5.1.1⁶,¹⁰.0¹,⁹.0²,⁶.0¹⁶,¹⁹]icosa-2,13(19),16-triene-17-carboxylate
(1r,4s,5r,6r,7r,11z)-4-ethyl-7-hydroxy-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-5-yl acetate
21-hydroxy-5,6,10,11-tetramethoxy-16-azapentacyclo[12.7.0.0²,⁷.0⁸,¹³.0¹⁶,²⁰]henicosa-1(14),2(7),3,5,8(13),9,11-heptaen-16-ium-16-olate
C24H27NO6 (425.18382820000005)
2,4-dihydroxy-3-({1-hydroxy-3-[(1s,5s)-5-methyl-9-methylidene-4-oxotricyclo[6.2.2.0¹,⁶]dodec-2-en-5-yl]propylidene}amino)benzoic acid
C24H27NO6 (425.18382820000005)
(3z,6s)-3-({5-[(2s)-2,3-dihydroxy-3-methylbutyl]-2-(2-methylbut-3-en-2-yl)-1h-indol-3-yl}methylidene)-6-methyl-6h-pyrazine-2,5-diol
C24H31N3O4 (425.23144460000003)
(2e,10e)-n-[(2r,3s,4as,8r,8ar)-8-chloro-2,4a-dihydroxy-8a-methyl-5-oxo-2,3,4,8-tetrahydro-1-benzopyran-3-yl]dodeca-2,10-dienimidic acid
C22H32ClNO5 (425.19688920000004)
(1r,4s,8r,9s,19r)-9-ethyl-4,9-dihydroxy-4-isopropyl-8-methyl-2,7,11-trioxa-16-azatricyclo[11.5.1.0¹⁶,¹⁹]nonadec-13-ene-3,6,10-trione
7-[4-(5-cyclohexylpenta-2,4-dienamido)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl]hepta-2,4,6-trienoic acid
C24H27NO6 (425.18382820000005)
7-(2-hydroxyethyl)-9a-methyl-3-octanoyl-6-(prop-1-en-1-yl)furo[3,2-g]isoquinoline-2,9-dione
(2e,4e,6e)-7-[(1s,2r,6r)-4-{[(2e,4e)-5-cyclohexyl-1-hydroxypenta-2,4-dien-1-ylidene]amino}-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl]hepta-2,4,6-trienoic acid
C24H27NO6 (425.18382820000005)
n-[(2s)-1-{[(4r,5as,9s,9as)-4-chloro-6,6,9a-trimethyl-3-oxo-1h,4h,5h,5ah,7h,8h,9h-naphtho[1,2-c]furan-9-yl]oxy}-3-methyl-1-oxobutan-2-yl]ethanimidic acid
C22H32ClNO5 (425.19688920000004)
3-{[5-(2,3-dihydroxy-3-methylbutyl)-2-(2-methylbut-3-en-2-yl)-1h-indol-3-yl]methylidene}-5-hydroxy-6-methyl-1,6-dihydropyrazin-2-one
C24H31N3O4 (425.23144460000003)
3-[2-(hydroxymethyl)-3-methoxyphenyl]-2-(4-methoxyphenyl)-10-methyl-2-azatricyclo[6.3.1.0⁴,¹²]dodeca-1(11),3,6,8(12),9-pentaen-5-one
C27H23NO4 (425.16269980000004)
3-[(1s,2s,4ar,8as)-2,6-dimethyl-1,2,4a,5,8,8a-hexahydronaphthalene-1-carbonyl]-1,4-dihydroxy-5-{2-hydroxy-7-oxabicyclo[4.1.0]hept-2-en-3-yl}pyridin-2-one
C24H27NO6 (425.18382820000005)
(2r)-2-[(9ar)-3-hexanoyl-9a-methyl-2,9-dioxo-6-[(1e)-prop-1-en-1-yl]furo[3,2-g]isoquinolin-7-yl]propanoic acid
C24H27NO6 (425.18382820000005)
(10e)-11-{[(1s,2s,4s,5s,6s,7r,8s)-1,5,7-trihydroxy-10-oxo-3-oxatricyclo[4.3.1.0²,⁴]decan-8-yl]-c-hydroxycarbonimidoyl}undec-10-enoic acid
7-(2-hydroxyethyl)-9a-methyl-3-octanoyl-6-[(1z)-prop-1-en-1-yl]furo[3,2-g]isoquinoline-2,9-dione
(3z,6s)-3-({5-[(2r)-2,3-dihydroxy-3-methylbutyl]-2-(2-methylbut-3-en-2-yl)-1h-indol-3-yl}methylidene)-6-methyl-6h-pyrazine-2,5-diol
C24H31N3O4 (425.23144460000003)