Exact Mass: 415.1995
Exact Mass Matches: 415.1995
Found 167 metabolites which its exact mass value is equals to given mass value 415.1995,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
CID 9844747
4-fluoro-N-(2-{4-[2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-5-yl]piperazin-1-yl}ethyl)benzamide
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents Flesinoxan is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM. Flesinoxan also has effective anxiolytic/antidepressant effects[1][2][3].
Protostemotinine
(1S,4S,13S)-4-methoxy-3,11-dimethyl-4-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]spiro[5-azatricyclo[8.3.0.01,5]tridec-10-ene-13,5-furan]-2,12-dione
Protostemotinine is a natural product found in Stemona sessilifolia, Stemona kerrii, and Stemona japonica with data available. Protostemotinine is an alkaloid isolated from the roots and rhizomes of Stemona sessilifolia. Protostemotinine is an alkaloid isolated from the roots and rhizomes of Stemona sessilifolia.
Ala Pro Gln Thr
(2S,3R)-2-[(2S)-2-{[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidin-2-yl]formamido}-4-carbamoylbutanamido]-3-hydroxybutanoic acid
Ala Pro Thr Gln
(2S)-2-[(2S,3R)-2-{[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidin-2-yl]formamido}-3-hydroxybutanamido]-4-carbamoylbutanoic acid
Ala Gln Pro Thr
(2S,3R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-4-carbamoylbutanoyl]pyrrolidin-2-yl]formamido}-3-hydroxybutanoic acid
Ala Gln Thr Pro
(2S)-1-[(2S,3R)-2-[(2S)-2-[(2S)-2-aminopropanamido]-4-carbamoylbutanamido]-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid
Ala Thr Pro Gln
(2S)-2-{[(2S)-1-[(2S,3R)-2-[(2S)-2-aminopropanamido]-3-hydroxybutanoyl]pyrrolidin-2-yl]formamido}-4-carbamoylbutanoic acid
Ala Thr Gln Pro
(2S)-1-[(2S)-2-[(2S,3R)-2-[(2S)-2-aminopropanamido]-3-hydroxybutanamido]-4-carbamoylbutanoyl]pyrrolidine-2-carboxylic acid
Asp Gly Lys Pro
(2S)-1-[(2S)-6-amino-2-{2-[(2S)-2-amino-3-carboxypropanamido]acetamido}hexanoyl]pyrrolidine-2-carboxylic acid
Asp Gly Pro Lys
(2S)-6-amino-2-{[(2S)-1-{2-[(2S)-2-amino-3-carboxypropanamido]acetyl}pyrrolidin-2-yl]formamido}hexanoic acid
Asp Lys Gly Pro
(2S)-1-{2-[(2S)-6-amino-2-[(2S)-2-amino-3-carboxypropanamido]hexanamido]acetyl}pyrrolidine-2-carboxylic acid
Asp Lys Pro Gly
(3S)-3-amino-3-{[(2S)-6-amino-1-[(2S)-2-[(carboxymethyl)carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}propanoic acid
Asp Pro Gly Lys
(2S)-6-amino-2-(2-{[(2S)-1-[(2S)-2-amino-3-carboxypropanoyl]pyrrolidin-2-yl]formamido}acetamido)hexanoic acid
Asp Pro Lys Gly
(3S)-3-amino-4-[(2S)-2-{[(1S)-5-amino-1-[(carboxymethyl)carbamoyl]pentyl]carbamoyl}pyrrolidin-1-yl]-4-oxobutanoic acid
Gly Asp Lys Pro
(2S)-1-[(2S)-6-amino-2-[(2S)-2-(2-aminoacetamido)-3-carboxypropanamido]hexanoyl]pyrrolidine-2-carboxylic acid
Gly Asp Pro Lys
(2S)-6-amino-2-{[(2S)-1-[(2S)-2-(2-aminoacetamido)-3-carboxypropanoyl]pyrrolidin-2-yl]formamido}hexanoic acid
Gly Lys Asp Pro
(2S)-1-[(2S)-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]-3-carboxypropanoyl]pyrrolidine-2-carboxylic acid
Gly Lys Pro Asp
(2S)-2-{[(2S)-1-[(2S)-6-amino-2-(2-aminoacetamido)hexanoyl]pyrrolidin-2-yl]formamido}butanedioic acid
Gly Pro Asp Lys
(2S)-6-amino-2-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-3-carboxypropanamido]hexanoic acid
Gly Pro Lys Asp
(2S)-2-[(2S)-6-amino-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}hexanamido]butanedioic acid
Lys Asp Gly Pro
(2S)-1-{2-[(2S)-3-carboxy-2-[(2S)-2,6-diaminohexanamido]propanamido]acetyl}pyrrolidine-2-carboxylic acid
Lys Asp Pro Gly
(3S)-4-[(2S)-2-[(carboxymethyl)carbamoyl]pyrrolidin-1-yl]-3-[(2S)-2,6-diaminohexanamido]-4-oxobutanoic acid
Lys Gly Asp Pro
(2S)-1-[(2S)-3-carboxy-2-{2-[(2S)-2,6-diaminohexanamido]acetamido}propanoyl]pyrrolidine-2-carboxylic acid
Lys Gly Pro Asp
(2S)-2-{[(2S)-1-{2-[(2S)-2,6-diaminohexanamido]acetyl}pyrrolidin-2-yl]formamido}butanedioic acid
Lys Pro Asp Gly
(3S)-3-[(carboxymethyl)carbamoyl]-3-{[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidin-2-yl]formamido}propanoic acid
Lys Pro Gly Asp
(2S)-2-(2-{[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidin-2-yl]formamido}acetamido)butanedioic acid
Asn Pro Ser Val
(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-carbamoylpropanoyl]pyrrolidin-2-yl]formamido}-3-hydroxypropanamido]-3-methylbutanoic acid
Asn Pro Val Ser
(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-carbamoylpropanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanamido]-3-hydroxypropanoic acid
Asn Ser Pro Val
(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxypropanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanoic acid
Asn Ser Val Pro
(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxypropanamido]-3-methylbutanoyl]pyrrolidine-2-carboxylic acid
Asn Val Pro Ser
(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-methylbutanoyl]pyrrolidin-2-yl]formamido}-3-hydroxypropanoic acid
Asn Val Ser Pro
(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-methylbutanamido]-3-hydroxypropanoyl]pyrrolidine-2-carboxylic acid
Pro Ala Gln Thr
(2S,3R)-2-[(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]butanamido]-3-hydroxybutanoic acid
Pro Ala Thr Gln
(2S)-4-carbamoyl-2-[(2S,3R)-3-hydroxy-2-[(2S)-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]butanamido]butanoic acid
Pro Asp Gly Lys
(2S)-6-amino-2-{2-[(2S)-3-carboxy-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]acetamido}hexanoic acid
Pro Asp Lys Gly
(3S)-3-{[(1S)-5-amino-1-[(carboxymethyl)carbamoyl]pentyl]carbamoyl}-3-[(2S)-pyrrolidin-2-ylformamido]propanoic acid
Pro Gly Asp Lys
(2S)-6-amino-2-[(2S)-3-carboxy-2-{2-[(2S)-pyrrolidin-2-ylformamido]acetamido}propanamido]hexanoic acid
Pro Gly Lys Asp
(2S)-2-[(2S)-6-amino-2-{2-[(2S)-pyrrolidin-2-ylformamido]acetamido}hexanamido]butanedioic acid
Pro Lys Asp Gly
(3S)-3-[(2S)-6-amino-2-[(2S)-pyrrolidin-2-ylformamido]hexanamido]-3-[(carboxymethyl)carbamoyl]propanoic acid
Pro Lys Gly Asp
(2S)-2-{2-[(2S)-6-amino-2-[(2S)-pyrrolidin-2-ylformamido]hexanamido]acetamido}butanedioic acid
Pro Asn Ser Val
(2S)-2-[(2S)-2-[(2S)-3-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]-3-hydroxypropanamido]-3-methylbutanoic acid
Pro Asn Val Ser
(2S)-2-[(2S)-2-[(2S)-3-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]-3-methylbutanamido]-3-hydroxypropanoic acid
Pro Gln Ala Thr
(2S,3R)-2-[(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]butanamido]propanamido]-3-hydroxybutanoic acid
Pro Gln Thr Ala
(2S)-2-[(2S,3R)-2-[(2S)-4-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]butanamido]-3-hydroxybutanamido]propanoic acid
Pro Ser Asn Val
(2S)-2-[(2S)-3-carbamoyl-2-[(2S)-3-hydroxy-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]propanamido]-3-methylbutanoic acid
Pro Ser Val Asn
(2S)-3-carbamoyl-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]-3-methylbutanamido]propanoic acid
Pro Thr Ala Gln
(2S)-4-carbamoyl-2-[(2S)-2-[(2S,3R)-3-hydroxy-2-[(2S)-pyrrolidin-2-ylformamido]butanamido]propanamido]butanoic acid
Pro Thr Gln Ala
(2S)-2-[(2S)-4-carbamoyl-2-[(2S,3R)-3-hydroxy-2-[(2S)-pyrrolidin-2-ylformamido]butanamido]butanamido]propanoic acid
Pro Val Asn Ser
(2S)-2-[(2S)-3-carbamoyl-2-[(2S)-3-methyl-2-[(2S)-pyrrolidin-2-ylformamido]butanamido]propanamido]-3-hydroxypropanoic acid
Pro Val Ser Asn
(2S)-3-carbamoyl-2-[(2S)-3-hydroxy-2-[(2S)-3-methyl-2-[(2S)-pyrrolidin-2-ylformamido]butanamido]propanamido]propanoic acid
Gln Ala Pro Thr
(2S,3R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]propanoyl]pyrrolidin-2-yl]formamido}-3-hydroxybutanoic acid
Gln Ala Thr Pro
(2S)-1-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]propanamido]-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid
Gln Pro Ala Thr
(2S,3R)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-4-carbamoylbutanoyl]pyrrolidin-2-yl]formamido}propanamido]-3-hydroxybutanoic acid
Gln Pro Thr Ala
(2S)-2-[(2S,3R)-2-{[(2S)-1-[(2S)-2-amino-4-carbamoylbutanoyl]pyrrolidin-2-yl]formamido}-3-hydroxybutanamido]propanoic acid
Gln Thr Ala Pro
(2S)-1-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxybutanamido]propanoyl]pyrrolidine-2-carboxylic acid
Gln Thr Pro Ala
(2S)-2-{[(2S)-1-[(2S,3R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxybutanoyl]pyrrolidin-2-yl]formamido}propanoic acid
Ser Asn Pro Val
(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-carbamoylpropanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanoic acid
Ser Asn Val Pro
(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-carbamoylpropanamido]-3-methylbutanoyl]pyrrolidine-2-carboxylic acid
Ser Pro Asn Val
(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-hydroxypropanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanamido]-3-methylbutanoic acid
Ser Pro Val Asn
(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-hydroxypropanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanamido]-3-carbamoylpropanoic acid
Ser Val Asn Pro
(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-methylbutanamido]-3-carbamoylpropanoyl]pyrrolidine-2-carboxylic acid
Ser Val Pro Asn
(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-methylbutanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanoic acid
Thr Ala Pro Gln
(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]propanoyl]pyrrolidin-2-yl]formamido}-4-carbamoylbutanoic acid
Thr Ala Gln Pro
(2S)-1-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]propanamido]-4-carbamoylbutanoyl]pyrrolidine-2-carboxylic acid
Thr Pro Ala Gln
(2S)-2-[(2S)-2-{[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidin-2-yl]formamido}propanamido]-4-carbamoylbutanoic acid
Thr Pro Gln Ala
(2S)-2-[(2S)-2-{[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidin-2-yl]formamido}-4-carbamoylbutanamido]propanoic acid
Thr Gln Ala Pro
(2S)-1-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carbamoylbutanamido]propanoyl]pyrrolidine-2-carboxylic acid
Thr Gln Pro Ala
(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carbamoylbutanoyl]pyrrolidin-2-yl]formamido}propanoic acid
Val Asn Pro Ser
(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-carbamoylpropanoyl]pyrrolidin-2-yl]formamido}-3-hydroxypropanoic acid
Val Asn Ser Pro
(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-carbamoylpropanamido]-3-hydroxypropanoyl]pyrrolidine-2-carboxylic acid
Val Pro Asn Ser
(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanamido]-3-hydroxypropanoic acid
Val Pro Ser Asn
(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]formamido}-3-hydroxypropanamido]-3-carbamoylpropanoic acid
Val Ser Asn Pro
(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-hydroxypropanamido]-3-carbamoylpropanoyl]pyrrolidine-2-carboxylic acid
Val Ser Pro Asn
(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-hydroxypropanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanoic acid
5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]-1H-indole hydrochloride
5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]-1H-indole hydrochloride
Donepezil Hydrochloride
Donepezil Hydrochloride
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors D002491 - Central Nervous System Agents > D018697 - Nootropic Agents C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor D004791 - Enzyme Inhibitors
Coelenterazine cp
8-(cyclopentylmethyl)-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-7H-imidazo[1,2-a]pyrazin-3-one
1,11-bis(trimethoxysilyl)-4-oxa-8-azaundecan-6-ol,50 in methanol
1,11-bis(trimethoxysilyl)-4-oxa-8-azaundecan-6-ol,50 in methanol
methyl 2-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)ethylidene]-1,3,3-trimethylindoline-5-carboxylate
methyl 2-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)ethylidene]-1,3,3-trimethylindoline-5-carboxylate
(S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole
(S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole
1-(phenylmethyl)-N-(2,4,6-trimethylphenyl)sulfonyl-4-piperidinecarbohydrazide
1-(phenylmethyl)-N-(2,4,6-trimethylphenyl)sulfonyl-4-piperidinecarbohydrazide
1-{[(1E)-(3-Hydroxy-2-methyl-5-{[(trihydroxy-lambda^5^-phosphanyl)oxy]methyl}pyridin-4-YL)methylidene]amino}undecan-2-one
1-{[(1E)-(3-Hydroxy-2-methyl-5-{[(trihydroxy-lambda^5^-phosphanyl)oxy]methyl}pyridin-4-YL)methylidene]amino}undecan-2-one
N-[4-(4-methylphenoxy)phenyl]-2-[2-(2-oxopyrrolidin-1-yl)anilino]acetamide
N-[4-(4-methylphenoxy)phenyl]-2-[2-(2-oxopyrrolidin-1-yl)anilino]acetamide
(10S,12S)-3-acetyl-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.02,10.04,9.015,20]henicosa-4,6,8,15,17,19-hexaene-13,21-dione
(10S,12S)-3-acetyl-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.02,10.04,9.015,20]henicosa-4,6,8,15,17,19-hexaene-13,21-dione
3,6-Bis(dimethylamino)-9-(2-(ethoxycarbonyl)-phenyl)xanthylium
3,6-Bis(dimethylamino)-9-(2-(ethoxycarbonyl)-phenyl)xanthylium
(3S,3aR,8aS,8bS)-5-ethyl-2-(phenylmethyl)spiro[1H-indole-3,4-3a,6,7,8,8a,8b-hexahydropyrrolo[3,4-a]pyrrolizine]-1,2,3-trione
(3S,3aR,8aS,8bS)-5-ethyl-2-(phenylmethyl)spiro[1H-indole-3,4-3a,6,7,8,8a,8b-hexahydropyrrolo[3,4-a]pyrrolizine]-1,2,3-trione
1-acetyl-N-[3-(N-ethyl-3-methylanilino)propyl]-2,3-dihydroindole-5-sulfonamide
1-acetyl-N-[3-(N-ethyl-3-methylanilino)propyl]-2,3-dihydroindole-5-sulfonamide
1-(4-tert-butylphenyl)sulfonyl-N-(2-pyridinylmethyl)-2-piperidinecarboxamide
1-(4-tert-butylphenyl)sulfonyl-N-(2-pyridinylmethyl)-2-piperidinecarboxamide
5-(Pentoxymethyl)-3-[(2E)-2-[(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]propyl]oxolan-2-one
5-(Pentoxymethyl)-3-[(2E)-2-[(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]propyl]oxolan-2-one
1-(5,6-Dihydrobenzo[b][1]benzazepin-11-yl)-2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]ethanone
1-(5,6-Dihydrobenzo[b][1]benzazepin-11-yl)-2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]ethanone
2-[(2R,5R,6S)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2R,5R,6S)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2S,5S,6S)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2S,5S,6S)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-fluoro-N-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
[(1R,2aR,8bR)-1-(hydroxymethyl)-2-[(2-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-(3-pyridinyl)methanone
[(1R,2aR,8bR)-1-(hydroxymethyl)-2-[(2-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-(3-pyridinyl)methanone
[(1S,2aR,8bR)-1-(hydroxymethyl)-2-[(2-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-(3-pyridinyl)methanone
[(1S,2aR,8bR)-1-(hydroxymethyl)-2-[(2-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-(3-pyridinyl)methanone
1-[(2R,3R)-6-[(2,5-difluorophenyl)methyl]-2-(hydroxymethyl)-3-phenyl-1,6-diazaspiro[3.3]heptan-1-yl]-2-(dimethylamino)ethanone
1-[(2R,3R)-6-[(2,5-difluorophenyl)methyl]-2-(hydroxymethyl)-3-phenyl-1,6-diazaspiro[3.3]heptan-1-yl]-2-(dimethylamino)ethanone
4-[4-[(2S,3R)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile
4-[4-[(2S,3R)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile
4-[4-[(2R,3R)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile
4-[4-[(2R,3R)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile
2-[(2R,5S,6R)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2R,5S,6R)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2S,5R,6S)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2S,5R,6S)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2S,5S,6R)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2S,5S,6R)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2R,5R,6R)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2R,5R,6R)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2R,5S,6S)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2R,5S,6S)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2S,5R,6R)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-[(2S,5R,6R)-5-[[(2-fluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(phenylmethyl)acetamide
2-fluoro-N-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2S,3S,6S)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2S,3S,6S)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2S,3S,6R)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2S,3S,6R)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2R,3R,6S)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
2-fluoro-N-[(2R,3R,6S)-2-(hydroxymethyl)-6-[2-[[1-oxo-2-(2-pyridinyl)ethyl]amino]ethyl]-3-oxanyl]benzamide
[(1R,2aS,8bS)-1-(hydroxymethyl)-2-[(2-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-(3-pyridinyl)methanone
[(1R,2aS,8bS)-1-(hydroxymethyl)-2-[(2-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-(3-pyridinyl)methanone
[(1S,2aS,8bS)-1-(hydroxymethyl)-2-[(2-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-(3-pyridinyl)methanone
[(1S,2aS,8bS)-1-(hydroxymethyl)-2-[(2-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-(3-pyridinyl)methanone
[(1S,2aS,8bS)-1-(hydroxymethyl)-2-[(3-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-pyridin-4-ylmethanone
[(1S,2aS,8bS)-1-(hydroxymethyl)-2-[(3-methoxyphenyl)methyl]-1,2a,3,8b-tetrahydroazeto[2,3-c]quinolin-4-yl]-pyridin-4-ylmethanone
1-[(2S,3R)-6-[(2,5-difluorophenyl)methyl]-2-(hydroxymethyl)-3-phenyl-1,6-diazaspiro[3.3]heptan-1-yl]-2-(dimethylamino)ethanone
1-[(2S,3R)-6-[(2,5-difluorophenyl)methyl]-2-(hydroxymethyl)-3-phenyl-1,6-diazaspiro[3.3]heptan-1-yl]-2-(dimethylamino)ethanone
4-[4-[(2S,3S)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile
4-[4-[(2S,3S)-1-acetyl-6-[cyclopropyl(oxo)methyl]-2-(hydroxymethyl)-1,6-diazaspiro[3.3]heptan-3-yl]phenyl]benzonitrile
(2R,3R)-6-[(3,5-difluorophenyl)methyl]-2-(hydroxymethyl)-3-phenyl-N-propan-2-yl-1,6-diazaspiro[3.3]heptane-1-carboxamide
(2R,3R)-6-[(3,5-difluorophenyl)methyl]-2-(hydroxymethyl)-3-phenyl-N-propan-2-yl-1,6-diazaspiro[3.3]heptane-1-carboxamide
ALM301
ALM301
ALM301 is an orally active highly specific AKT inhibitor with IC50 values of 0.13 μM, 0.09 μM and 2.75 μM for AKT1, AKT2 and AKT3, respectively. ALM301 inhibits AKT phosphorylation and modulates downstream signalling in vitro. ALM301 can inhibit cancer cell proliferation and tumor growth[1].
4-methoxy-3-methyl-5-[(1s,2r,3s,4e,11s)-3-methyl-11-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-5-oxa-10-azatricyclo[8.3.0.0²,⁶]tridec-6-en-4-ylidene]furan-2-one
4-methoxy-3-methyl-5-[(1s,2r,3s,4e,11s)-3-methyl-11-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-5-oxa-10-azatricyclo[8.3.0.0²,⁶]tridec-6-en-4-ylidene]furan-2-one
(1'r,2s,11's)-3-methoxy-4,4'-dimethyl-11'-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-10'-azaspiro[furan-2,2'-tricyclo[8.3.0.0¹,⁵]tridecan]-4'-ene-3',5-dione
(1'r,2s,11's)-3-methoxy-4,4'-dimethyl-11'-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-10'-azaspiro[furan-2,2'-tricyclo[8.3.0.0¹,⁵]tridecan]-4'-ene-3',5-dione
(6e)-8-({4,8-dimethoxyfuro[2,3-b]quinolin-7-yl}oxy)-2,6-dimethyloct-6-ene-2,3-diol
(6e)-8-({4,8-dimethoxyfuro[2,3-b]quinolin-7-yl}oxy)-2,6-dimethyloct-6-ene-2,3-diol
3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
methyl (2z,3e,5e,7e,9e)-11-[(3as,6r)-3a,5-dihydroxy-2h,3h,6h,6ah-furo[3,2-b]pyrrol-6-yl]-2-ethylidene-4,6,10-trimethyl-11-oxoundeca-3,5,7,9-tetraenoate
methyl (2z,3e,5e,7e,9e)-11-[(3as,6r)-3a,5-dihydroxy-2h,3h,6h,6ah-furo[3,2-b]pyrrol-6-yl]-2-ethylidene-4,6,10-trimethyl-11-oxoundeca-3,5,7,9-tetraenoate
(3s,6z)-8-({4,8-dimethoxyfuro[2,3-b]quinolin-7-yl}oxy)-2,6-dimethyloct-6-ene-2,3-diol
(3s,6z)-8-({4,8-dimethoxyfuro[2,3-b]quinolin-7-yl}oxy)-2,6-dimethyloct-6-ene-2,3-diol
(1s,11r,18r)-4,5,15,16,18-pentamethoxy-10-methyl-19-oxa-10-azatetracyclo[9.8.0.0²,⁷.0¹²,¹⁷]nonadeca-2(7),3,5,12(17),13,15-hexaene
(1s,11r,18r)-4,5,15,16,18-pentamethoxy-10-methyl-19-oxa-10-azatetracyclo[9.8.0.0²,⁷.0¹²,¹⁷]nonadeca-2(7),3,5,12(17),13,15-hexaene
4-[5-methoxy-2-methyl-2-(4-methyl-2-oxopent-3-en-1-yl)-7-oxo-3h,4h,9h-pyrano[2,3-e]isoindol-8-yl]butanoic acid
4-[5-methoxy-2-methyl-2-(4-methyl-2-oxopent-3-en-1-yl)-7-oxo-3h,4h,9h-pyrano[2,3-e]isoindol-8-yl]butanoic acid
8-({4,8-dimethoxyfuro[2,3-b]quinolin-7-yl}oxy)-2,6-dimethyloct-6-ene-2,3-diol
8-({4,8-dimethoxyfuro[2,3-b]quinolin-7-yl}oxy)-2,6-dimethyloct-6-ene-2,3-diol
(2s,10s,12s)-3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
(2s,10s,12s)-3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
(3s,6e)-8-({4,8-dimethoxyfuro[2,3-b]quinolin-7-yl}oxy)-2,6-dimethyloct-6-ene-2,3-diol
(3s,6e)-8-({4,8-dimethoxyfuro[2,3-b]quinolin-7-yl}oxy)-2,6-dimethyloct-6-ene-2,3-diol
(2r,10r,12r)-3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
(2r,10r,12r)-3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
3,5,7-trihydroxy-6-[(4e,6e)-3-oxotetradeca-4,6-dien-1-yl]-1h-isoindole-4-carboxylic acid
3,5,7-trihydroxy-6-[(4e,6e)-3-oxotetradeca-4,6-dien-1-yl]-1h-isoindole-4-carboxylic acid
methyl (2r,3s,6z,8s,9r,15r)-15-(dimethylamino)-8-hydroxy-5-oxo-2,9-bis(prop-1-en-2-yl)-4,14-dioxatricyclo[9.2.1.1³,⁶]pentadeca-1(13),6,11-triene-12-carboxylate
methyl (2r,3s,6z,8s,9r,15r)-15-(dimethylamino)-8-hydroxy-5-oxo-2,9-bis(prop-1-en-2-yl)-4,14-dioxatricyclo[9.2.1.1³,⁶]pentadeca-1(13),6,11-triene-12-carboxylate
(1s,11r,18s)-4,5,15,16,18-pentamethoxy-10-methyl-19-oxa-10-azatetracyclo[9.8.0.0²,⁷.0¹²,¹⁷]nonadeca-2(7),3,5,12(17),13,15-hexaene
(1s,11r,18s)-4,5,15,16,18-pentamethoxy-10-methyl-19-oxa-10-azatetracyclo[9.8.0.0²,⁷.0¹²,¹⁷]nonadeca-2(7),3,5,12(17),13,15-hexaene
3,5,7-trihydroxy-6-(3-oxotetradeca-4,6-dien-1-yl)-1h-isoindole-4-carboxylic acid
3,5,7-trihydroxy-6-(3-oxotetradeca-4,6-dien-1-yl)-1h-isoindole-4-carboxylic acid
(2s,10s,12r)-3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
(2s,10s,12r)-3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
3-methoxy-4,4'-dimethyl-11'-(4-methyl-5-oxooxolan-2-yl)-10'-azaspiro[furan-2,2'-tricyclo[8.3.0.0¹,⁵]tridecan]-4'-ene-3',5-dione
3-methoxy-4,4'-dimethyl-11'-(4-methyl-5-oxooxolan-2-yl)-10'-azaspiro[furan-2,2'-tricyclo[8.3.0.0¹,⁵]tridecan]-4'-ene-3',5-dione
methyl (3s,6e,15r)-15-(dimethylamino)-8-hydroxy-5-oxo-2,9-bis(prop-1-en-2-yl)-4,14-dioxatricyclo[9.2.1.1³,⁶]pentadeca-1(13),6,11-triene-12-carboxylate
methyl (3s,6e,15r)-15-(dimethylamino)-8-hydroxy-5-oxo-2,9-bis(prop-1-en-2-yl)-4,14-dioxatricyclo[9.2.1.1³,⁶]pentadeca-1(13),6,11-triene-12-carboxylate
4,5,15,16,18-pentamethoxy-10-methyl-19-oxa-10-azatetracyclo[9.8.0.0²,⁷.0¹²,¹⁷]nonadeca-2(7),3,5,12(17),13,15-hexaene
4,5,15,16,18-pentamethoxy-10-methyl-19-oxa-10-azatetracyclo[9.8.0.0²,⁷.0¹²,¹⁷]nonadeca-2(7),3,5,12(17),13,15-hexaene
4-methoxy-3-methyl-5-[(1s,2r,3s,4z,11s)-3-methyl-11-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-5-oxa-10-azatricyclo[8.3.0.0²,⁶]tridec-6-en-4-ylidene]furan-2-one
4-methoxy-3-methyl-5-[(1s,2r,3s,4z,11s)-3-methyl-11-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-5-oxa-10-azatricyclo[8.3.0.0²,⁶]tridec-6-en-4-ylidene]furan-2-one
(2r,10r,12s)-3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
(2r,10r,12s)-3-acetyl-13-hydroxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-4,6,8,13,15,17,19-heptaen-21-one
4-methoxy-3-methyl-5-[(4e)-3-methyl-11-(4-methyl-5-oxooxolan-2-yl)-5-oxa-10-azatricyclo[8.3.0.0²,⁶]tridec-6-en-4-ylidene]furan-2-one
4-methoxy-3-methyl-5-[(4e)-3-methyl-11-(4-methyl-5-oxooxolan-2-yl)-5-oxa-10-azatricyclo[8.3.0.0²,⁶]tridec-6-en-4-ylidene]furan-2-one
methyl (1s,2r,6s,15s,16r)-1,18-dihydroxy-11-(2-hydroxyethyl)-2,15-dimethyl-9-oxo-4-azapentacyclo[11.4.1.0⁴,¹⁶.0⁶,¹⁵.0¹⁰,¹⁴]octadeca-10(14),11,13(18)-triene-12-carboxylate
methyl (1s,2r,6s,15s,16r)-1,18-dihydroxy-11-(2-hydroxyethyl)-2,15-dimethyl-9-oxo-4-azapentacyclo[11.4.1.0⁴,¹⁶.0⁶,¹⁵.0¹⁰,¹⁴]octadeca-10(14),11,13(18)-triene-12-carboxylate
(1's,2s,11's)-3-methoxy-4,4'-dimethyl-11'-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-10'-azaspiro[furan-2,2'-tricyclo[8.3.0.0¹,⁵]tridecan]-4'-ene-3',5-dione
(1's,2s,11's)-3-methoxy-4,4'-dimethyl-11'-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-10'-azaspiro[furan-2,2'-tricyclo[8.3.0.0¹,⁵]tridecan]-4'-ene-3',5-dione
methyl 15-(dimethylamino)-8-hydroxy-5-oxo-2,9-bis(prop-1-en-2-yl)-4,14-dioxatricyclo[9.2.1.1³,⁶]pentadeca-1(13),6,11-triene-12-carboxylate
methyl 15-(dimethylamino)-8-hydroxy-5-oxo-2,9-bis(prop-1-en-2-yl)-4,14-dioxatricyclo[9.2.1.1³,⁶]pentadeca-1(13),6,11-triene-12-carboxylate
methyl (3s,6z,15r)-15-(dimethylamino)-8-hydroxy-5-oxo-2,9-bis(prop-1-en-2-yl)-4,14-dioxatricyclo[9.2.1.1³,⁶]pentadeca-1(13),6,11-triene-12-carboxylate
methyl (3s,6z,15r)-15-(dimethylamino)-8-hydroxy-5-oxo-2,9-bis(prop-1-en-2-yl)-4,14-dioxatricyclo[9.2.1.1³,⁶]pentadeca-1(13),6,11-triene-12-carboxylate
(1's,2r,11's)-3-methoxy-4,4'-dimethyl-11'-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-10'-azaspiro[furan-2,2'-tricyclo[8.3.0.0¹,⁵]tridecan]-4'-ene-3',5-dione
(1's,2r,11's)-3-methoxy-4,4'-dimethyl-11'-[(2s,4s)-4-methyl-5-oxooxolan-2-yl]-10'-azaspiro[furan-2,2'-tricyclo[8.3.0.0¹,⁵]tridecan]-4'-ene-3',5-dione
