Exact Mass: 405.20457960000005

Exact Mass Matches: 405.20457960000005

Found 500 metabolites which its exact mass value is equals to given mass value 405.20457960000005, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Clomifene

2-(4-(2-Chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethylethanamine

C26H28ClNO (405.18593080000005)

Clomifene is only found in individuals that have used or taken this drug. It is a triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. [PubChem]Clomifene has both estrogenic and anti-estrogenic properties, but its precise mechanism of action has not been determined. Clomifene appears to stumulate the release of gonadotropins, follicle-stimulating hormone (FSH), and leuteinizing hormone (LH), which leads to the development and maturation of ovarian follicle, ovulation, and subsequent development and function of the coprus luteum, thus resulting in pregnancy. Gonadotropin release may result from direct stimulation of the hypothalamic-pituitary axis or from a decreased inhibitory influence of estrogens on the hypothalamic-pituitary axis by competing with the endogenous estrogens of the uterus, pituitary, or hypothalamus. Clomifene has no apparent progestational, androgenic, or antrandrogenic effects and does not appear to interfere with pituitary-adrenal or pituitary-thyroid function. G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03G - Gonadotropins and other ovulation stimulants > G03GB - Ovulation stimulants, synthetic D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D020847 - Estrogen Receptor Modulators D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1821 - Selective Estrogen Receptor Modulator C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor > C1971 - Angiogenesis Activator Inhibitor C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen D012102 - Reproductive Control Agents > D005299 - Fertility Agents C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist C1892 - Chemopreventive Agent

Toremifene

(2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine

C26H28ClNO (405.18593080000005)

Toremifene is only found in individuals that have used or taken this drug. It is a first generation nonsteroidal selective estrogen receptor modulator (SERM) that is structurally related to tamoxifen. Like tamoxifen, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue. [PubChem]Toremifene is a nonsteroidal triphenylethylene derivative. Toremifene binds to estrogen receptors and may exert estrogenic, antiestrogenic, or both activities, depending upon the duration of treatment, animal species, gender, target organ, or endpoint selected. The antitumor effect of toremifene in breast cancer is believed to be mainly due to its antiestrogenic effects, in other words, its ability to compete with estrogen for binding sites in the cancer, blocking the growth-stimulating effects of estrogen in the tumor. Toremifene may also inhibit tumor growth through other mechanisms, such as induction of apoptosis, regulation of oncogene expression, and growth factors. L - Antineoplastic and immunomodulating agents > L02 - Endocrine therapy > L02B - Hormone antagonists and related agents > L02BA - Anti-estrogens D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D020847 - Estrogen Receptor Modulators C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1821 - Selective Estrogen Receptor Modulator C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist D050071 - Bone Density Conservation Agents D000970 - Antineoplastic Agents C1892 - Chemopreventive Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

Cypridina luciferin

Vargulin trifluoroacetate salt

C22H27N7O (405.2276972)

Icacine

C22H31NO6 (405.2151266)

clivorine

C21H27NO7 (405.17874320000004)

Lisinopril

N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline

C21H31N3O5 (405.2263596)

C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D020011 - Protective Agents > D002316 - Cardiotonic Agents COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.

N1-hydroxy-roquefortine C

C22H23N5O3 (405.18008080000004)

Lisinopril

(2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid

C21H31N3O5 (405.2263596)

One of the Angiotensin-converting enzyme inhibitors (ACE inhibitors), orally active, that has been used in the treatment of hypertension and congestive heart failure. -- Pubchem; Lisinopril is a drug of the angiotensin converting enzyme (ACE) inhibitor class that is primarily used in treatment of hypertension, congestive heart failure and heart attacks. Historically, lisinopril was the third ACE inhibitor, after captopril and enalapril that was introduced into therapy in early 1990s . Lisinopril has a number of properties that distinguish it from other ACE inhibitors: it is hydrophilic, has long half life and tissue penetration and is not metabolized by the liver. -- Wikipedia; Lisinopril is solely excreted in urine in the unchanged form. Elimination of the drug depends on glomerular filtration and tubular excretion. Rate of lisinopril elimination decreases with old age and kidney or heart failure. There is a relation between creatinine and lisinopril clearance. With prolonged therapy dose reduction can be necessary to avoid accumulation. -- Wikipedia [HMDB] One of the Angiotensin-converting enzyme inhibitors (ACE inhibitors), orally active, that has been used in the treatment of hypertension and congestive heart failure. -- Pubchem; Lisinopril is a drug of the angiotensin converting enzyme (ACE) inhibitor class that is primarily used in treatment of hypertension, congestive heart failure and heart attacks. Historically, lisinopril was the third ACE inhibitor, after captopril and enalapril that was introduced into therapy in early 1990s. Lisinopril has a number of properties that distinguish it from other ACE inhibitors: it is hydrophilic, has long half life and tissue penetration and is not metabolized by the liver. -- Wikipedia; Lisinopril is solely excreted in urine in the unchanged form. Elimination of the drug depends on glomerular filtration and tubular excretion. Rate of lisinopril elimination decreases with old age and kidney or heart failure. There is a relation between creatinine and lisinopril clearance. With prolonged therapy dose reduction can be necessary to avoid accumulation. -- Wikipedia.

Imidapril

(4S)-1-Methyl-3-[(2S)-2-[N-((1S)-1-ethoxycarbonyl-3-phenylpropyl)amino]propionyl]-2-oxo-imidazolidine-4-carboxylic acid

C20H27N3O6 (405.18997620000005)

Imidapril, also known as Tanatril (trade name), belongs to a class of long-acting, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitors (PMID: 12177688). It is a prodrug that is widely used in the treatment of mild to moderate essential hypertension (PMID: 17547476). A prodrug is a drug that must be metabolized in the body (via the gut or the liver) to become active. Imidapril is also prescribed to treat chronic congestive heart failure (CHF), acute myocardial infarction (AMI), and diabetic nephropathy (PMID: 12177688, 17094051). It functions through preventing angiotensin II formation, via inhibition of the angiotensin-converting enzyme (ACE), that results in reduction of peripheral resistance and a reduction in systemic blood pressure (BP) (PMID: 17547476). Imidapril is only found in individuals that have used or taken this drug. C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents

4-Oxofenretinide

N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamide

C26H31NO3 (405.2303816)

2-[4-(4-Chloro-1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine

2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine

C26H28ClNO (405.18593080000005)

Cypridina luciferin

N-{3-[2-(butan-2-yl)-3-hydroxy-6-(1H-indol-3-yl)imidazo[1,2-a]pyrazin-8-yl]propyl}guanidine

C22H27N7O (405.2276972)

Febarbamate

{[1-butoxy-3-(5-ethyl-4-hydroxy-2,6-dioxo-5-phenyl-1,2,5,6-tetrahydropyrimidin-1-yl)propan-2-yl]oxy}carboximidic acid

C20H27N3O6 (405.18997620000005)

M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents > M03BA - Carbamic acid esters C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent

Nifekalant

6-({2-[(2-hydroxyethyl)[3-(4-nitrophenyl)propyl]amino]ethyl}imino)-1,3-dimethyl-2-oxo-1,2,3,6-tetrahydropyrimidin-1-ium-4-olate

C19H27N5O5 (405.2012092)

D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents

Nitro-prednisolone

14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyl-3-nitrotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one

C21H27NO7 (405.17874320000004)

Terbogrel

6-[3-(N-tert-butyl-N-cyanocarbamimidamido)phenyl]-6-(pyridin-3-yl)hex-5-enoic acid

C23H27N5O2 (405.2164642)

trequinsin

2,3,6,7-Tetrahydro-9,10-dimethoxy-3-methyl-2-((2,4,6-trimethylphenyl)imino)-4H-pyrimido(6,1-a)isoquinolin-4-one, monohydrochloride

C24H27N3O3 (405.20523120000007)

D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor

3-[2-(1,1-dimethyl-allyl)-5-(3,3-dimethyl-oxiranylmethyl)-indol-3-ylmethylene]-6-methylene-piperazine-2,5-dione|Isoechinulin C|isoechinulin-C

C24H27N3O3 (405.20523120000007)

Oxystemokerrin

C22H31NO6 (405.2151266)

Neotuberostemonone

C22H31NO6 (405.2151266)

Ancistrobrevine C

C25H27NO4 (405.19399820000007)

NSC682457

C22H31NO6 (405.2151266)

Farinosone A

C25H27NO4 (405.19399820000007)

nifekalant

C19H27N5O5 (405.2012092)

C78274 - Agent Affecting Cardiovascular System > C47793 - Antiarrhythmic Agent D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents C93038 - Cation Channel Blocker

Hydroxy-roquefortine C

C22H23N5O3 (405.18008080000004)

CONFIDENCE Penicillium bissettii

Gerambullin

C22H31NO4S (405.19736860000006)

ancistrotanzanine A|ancistrotectorines D

C25H27NO4 (405.19399820000007)

(3E,5aS,10bR)-6,10b,11,11a-tetrahydro-11a-hydroxy-3-(1H-imidazol-5-ylmethylidene)-10b-(2-methylbut-3-en-2-yl)-2H-pyrazino[1,2:1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione|16-hydroxyroquefortine C

C22H23N5O3 (405.18008080000004)

Epothilone K

C22H31NO4S (405.19736860000006)

trachelogenin amide

C21H27NO7 (405.17874320000004)

1,2-didehydroancistrobertsonine D

C25H27NO4 (405.19399820000007)

ancistrotectoriline C

C25H27NO4 (405.19399820000007)

sessilifoliamide E

C22H31NO6 (405.2151266)

akirine

C22H31NO6 (405.2151266)

(S)-Cypridina luciferin|Cypridina luciferin|[3-(2-sec-butyl-6-indol-3-yl-3-oxo-3,7-dihydro-imidazo[1,2-a]pyrazin-8-yl)-propyl]-guanidine|{3-[2((S)-sec-Butyl)-6-indol-3-yl-3-oxo-3,7-dihydro-imidazo[1,2-a]pyrazin-8-yl]-propyl}-guanidin|{3-[2((S)-sec-butyl)-6-indol-3-yl-3-oxo-3,7-dihydro-imidazo[1,2-a]pyrazin-8-yl]-propyl}-guanidine

(S)-Cypridina luciferin|Cypridina luciferin|[3-(2-sec-butyl-6-indol-3-yl-3-oxo-3,7-dihydro-imidazo[1,2-a]pyrazin-8-yl)-propyl]-guanidine|{3-[2((S)-sec-Butyl)-6-indol-3-yl-3-oxo-3,7-dihydro-imidazo[1,2-a]pyrazin-8-yl]-propyl}-guanidin|{3-[2((S)-sec-butyl)-6-indol-3-yl-3-oxo-3,7-dihydro-imidazo[1,2-a]pyrazin-8-yl]-propyl}-guanidine

C22H27N7O (405.2276972)

(S,3Z)-3-((1,7-dihydro-7,7-dimethyl-2-(2-methylbut-3-en-2-yl)pyrano[2,3-g]indol-3-yl)methylene)-6-methylpiperazine-2,5-dione|talathermophilin B

C24H27N3O3 (405.20523120000007)

(+)-Halichlorine|chalichlorine|halichlorine

C23H32ClNO3 (405.2070592)

tuberostemonoxirine

C22H31NO6 (405.2151266)

stemona-amine B

C22H31NO6 (405.2151266)

(S)-cypridina luciferin|cypridina luciferin

C22H27N7O (405.2276972)

6-O-demethylancistroealaine A

C25H27NO4 (405.19399820000007)

maireistemoninol

C22H31NO6 (405.2151266)

SCHEMBL214410

C26H31NO3 (405.2303816)

corsutine

C21H27NO7 (405.17874320000004)

His Ile His

C18H27N7O4 (405.2124422)

Lys Arg Cys

C15H31N7O4S (405.21581260000005)

Tyr Pro Leu

C21H31N3O5 (405.2263596)

Leu Pro Tyr

C21H31N3O5 (405.2263596)

His His Ile

C18H27N7O4 (405.2124422)

Glu Met Leu

C17H31N3O6S (405.19334660000004)

Ile His His

C18H27N7O4 (405.2124422)

Arg Cys Gln

C14H27N7O5S (405.1794292)

Pro Leu Tyr

C21H31N3O5 (405.2263596)

Glu Leu Met

C17H31N3O6S (405.19334660000004)

Leu Met Glu

C17H31N3O6S (405.19334660000004)

Pro Tyr Leu

C21H31N3O5 (405.2263596)

Isoechinulin C

C24H27N3O3 (405.20523120000007)

Lisinopril (Zestril)

C21H31N3O5 (405.2263596)

Toremifene

C26H28ClNO (405.18593080000005)

L - Antineoplastic and immunomodulating agents > L02 - Endocrine therapy > L02B - Hormone antagonists and related agents > L02BA - Anti-estrogens D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D020847 - Estrogen Receptor Modulators C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1821 - Selective Estrogen Receptor Modulator C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist D050071 - Bone Density Conservation Agents D000970 - Antineoplastic Agents C1892 - Chemopreventive Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

Cypridinid luciferin

C22H27N7O (405.2276972)

Febarbamate

[1-butoxy-3-(5-ethyl-2,4,6-trioxo-5-phenyl-1,3-diazinan-1-yl)propan-2-yl] carbamate

C20H27N3O6 (405.18997620000005)

Imidapril

(4S)-3-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid

C20H27N3O6 (405.18997620000005)

Ala Cys Gly Arg

(2S)-2-{2-[(2R)-2-[(2S)-2-aminopropanamido]-3-sulfanylpropanamido]acetamido}-5-carbamimidamidopentanoic acid

C14H27N7O5S (405.1794292)

Ala Cys Arg Gly

2-[(2S)-2-[(2R)-2-[(2S)-2-aminopropanamido]-3-sulfanylpropanamido]-5-carbamimidamidopentanamido]acetic acid

C14H27N7O5S (405.1794292)

Ala Gly Cys Arg

(2S)-2-[(2R)-2-{2-[(2S)-2-aminopropanamido]acetamido}-3-sulfanylpropanamido]-5-carbamimidamidopentanoic acid

C14H27N7O5S (405.1794292)

Ala Gly Lys Met

(2S)-2-[(2S)-6-amino-2-{2-[(2S)-2-aminopropanamido]acetamido}hexanamido]-4-(methylsulfanyl)butanoic acid

C16H31N5O5S (405.20457960000005)

Ala Gly Met Lys

(2S)-6-amino-2-[(2S)-2-{2-[(2S)-2-aminopropanamido]acetamido}-4-(methylsulfanyl)butanamido]hexanoic acid

C16H31N5O5S (405.20457960000005)

Ala Gly Arg Cys

(2R)-2-[(2S)-2-{2-[(2S)-2-aminopropanamido]acetamido}-5-carbamimidamidopentanamido]-3-sulfanylpropanoic acid

C14H27N7O5S (405.1794292)

Ala Lys Gly Met

(2S)-2-{2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]acetamido}-4-(methylsulfanyl)butanoic acid

C16H31N5O5S (405.20457960000005)

Ala Lys Met Gly

2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-4-(methylsulfanyl)butanamido]acetic acid

C16H31N5O5S (405.20457960000005)

Ala Lys Ser Thr

(2S,3R)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-3-hydroxypropanamido]-3-hydroxybutanoic acid

C16H31N5O7 (405.2223376)

Ala Lys Thr Ser

(2S)-2-[(2S,3R)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-3-hydroxybutanamido]-3-hydroxypropanoic acid

C16H31N5O7 (405.2223376)

Ala Met Gly Lys

(2S)-6-amino-2-{2-[(2S)-2-[(2S)-2-aminopropanamido]-4-(methylsulfanyl)butanamido]acetamido}hexanoic acid

C16H31N5O5S (405.20457960000005)

Ala Met Lys Gly

2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-aminopropanamido]-4-(methylsulfanyl)butanamido]hexanamido]acetic acid

C16H31N5O5S (405.20457960000005)

Ala Asn Thr Thr

(2S,3R)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]-3-hydroxybutanamido]-3-hydroxybutanoic acid