Exact Mass: 389.0296340000001

Exact Mass Matches: 389.0296340000001

Found 28 metabolites which its exact mass value is equals to given mass value 389.0296340000001, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Cyclothiazide

3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ⁶,2,4-benzothiadiazine-7-sulfonamide

C14H16ClN3O4S2 (389.0270726)


As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter. This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. The antihypertensive mechanism of cyclothiazide is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium (KCa) channel, also found in the smooth muscle. Cyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D045283 - Natriuretic Agents > D004232 - Diuretics Same as: D01256 Cyclothiazide, a positive allosteric modulator of AMPA receptors, is used frequently to block the desensitization of both native and heterologously expressed AMPA receptors. Cyclothiazide is known to produce a fast inhibition of AMPA receptor desensitization and a much slower potentiation of the AMPA current[1].

   

3',6'-Dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one

3,6-Dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3H),9-[9H]xanthen]-3-one

C21H11NO5S (389.03579160000004)


   

Fluorescein-5-isothiocyanate

3,6-Dihydroxy-5-isothiocyanatospiro(isobenzofuran-1(3H),9-(9H)xanthen)-3-one

C21H11NO5S (389.03579160000004)


D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D004396 - Coloring Agents > D005456 - Fluorescent Dyes > D005452 - Fluoresceins

   

Fluoresceine isothiocyanate

3,6-dihydroxy-8-isothiocyanato-3H-spiro[2-benzofuran-1,9-xanthene]-3-one

C21H11NO5S (389.03579160000004)


   
   

Celastramycin A

(3-chloro-5-hexyl-2,6-dihydroxyphenyl)(4,5-dichloro-1H-pyrrol-3-yl)-methanone

C17H18Cl3NO3 (389.03522080000005)


   

cyclothiazide

cyclothiazide

C14H16ClN3O4S2 (389.0270726)


C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D045283 - Natriuretic Agents > D004232 - Diuretics Same as: D01256 Cyclothiazide, a positive allosteric modulator of AMPA receptors, is used frequently to block the desensitization of both native and heterologously expressed AMPA receptors. Cyclothiazide is known to produce a fast inhibition of AMPA receptor desensitization and a much slower potentiation of the AMPA current[1].

   

3-(4-BROMO-BENZENESULFONYL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

3-(4-BROMO-BENZENESULFONYL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

C15H20BrNO4S (389.0296340000001)


   

2-((tert-Butyldimethylsilyloxy)methyl)-6-iodofuro[3,2-b]pyridine

2-((tert-Butyldimethylsilyloxy)methyl)-6-iodofuro[3,2-b]pyridine

C14H20INO2Si (389.030801)


   

Thiazolidine, 2-(2-chlorophenyl)-3-(1-naphthalenylsulfonyl)- (9CI)

Thiazolidine, 2-(2-chlorophenyl)-3-(1-naphthalenylsulfonyl)- (9CI)

C19H16ClNO2S2 (389.0310946)


   
   

3-(2-BROMO-BENZENESULFONYL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

3-(2-BROMO-BENZENESULFONYL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

C15H20BrNO4S (389.0296340000001)


   

3-(3-BROMO-BENZENESULFONYL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

3-(3-BROMO-BENZENESULFONYL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

C15H20BrNO4S (389.0296340000001)


   

Fluorescein 6-isothiocyanate

Fluorescein isothiocyanate (Spiro Form)

C21H11NO5S (389.03579160000004)


   

PIK-93

N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide

C14H16ClN3O4S2 (389.0270726)


   

Thiazolidine, 2-(4-chlorophenyl)-3-(1-naphthalenylsulfonyl)- (9CI)

Thiazolidine, 2-(4-chlorophenyl)-3-(1-naphthalenylsulfonyl)- (9CI)

C19H16ClNO2S2 (389.0310946)


   

sodium 2-(2,3-dihydro-1,3-dioxo-1H-inden-2-yl)-8-methylquinoline-6-sulphonate

sodium 2-(2,3-dihydro-1,3-dioxo-1H-inden-2-yl)-8-methylquinoline-6-sulphonate

C19H12NNaO5S (389.03338620000005)


   
   
   

Benzenebutanoic acid, 2-hydroxy-3,4-dimethoxy-6-methyl-5-(sulfooxy)-, dipotassium salt

Benzenebutanoic acid, 2-hydroxy-3,4-dimethoxy-6-methyl-5-(sulfooxy)-, dipotassium salt

C13H18KO9S (389.03085780000004)


   

1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-[(1,3-benzothiazol-2-ylthio)methyl]-4-triazolecarboxylic acid methyl ester

1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-[(1,3-benzothiazol-2-ylthio)methyl]-4-triazolecarboxylic acid methyl ester

C14H11N7O3S2 (389.03647759999996)


   

8-Nitroguanosine 3,5-cyclic monophosphate(1-)

8-Nitroguanosine 3,5-cyclic monophosphate(1-)

C10H10N6O9P- (389.024688)


   

2-[2-(1,3-Benzothiazol-2-ylsulfonyl)ethylthio]-4,6-dimethyl-3-pyridinecarbonitrile

2-[2-(1,3-Benzothiazol-2-ylsulfonyl)ethylthio]-4,6-dimethyl-3-pyridinecarbonitrile

C17H15N3O2S3 (389.032637)


   

6-FITC

Fluorescein-5-isothiocyanate

C21H11NO5S (389.03579160000004)


D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D004396 - Coloring Agents > D005456 - Fluorescent Dyes > D005452 - Fluoresceins

   

n-[2-(3-bromo-4-hydroxyphenyl)ethenyl]-3-(4-hydroxyphenyl)-2-methoxyprop-2-enamide

n-[2-(3-bromo-4-hydroxyphenyl)ethenyl]-3-(4-hydroxyphenyl)-2-methoxyprop-2-enamide

C18H16BrNO4 (389.02626360000005)


   

(e,2z)-n-[(1e)-2-(3-bromo-4-hydroxyphenyl)ethenyl]-3-(4-hydroxyphenyl)-2-methoxyprop-2-enimidic acid

(e,2z)-n-[(1e)-2-(3-bromo-4-hydroxyphenyl)ethenyl]-3-(4-hydroxyphenyl)-2-methoxyprop-2-enimidic acid

C18H16BrNO4 (389.02626360000005)


   

4-chloro-2-(4,5-dichloro-1h-pyrrole-3-carbonyl)-6-hexylbenzene-1,3-diol

4-chloro-2-(4,5-dichloro-1h-pyrrole-3-carbonyl)-6-hexylbenzene-1,3-diol

C17H18Cl3NO3 (389.03522080000005)