Exact Mass: 387.1998318
Exact Mass Matches: 387.1998318
Found 95 metabolites which its exact mass value is equals to given mass value 387.1998318,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Terazosin
Terazosin is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH). It also acts to lower blood pressure, so it is a drug of choice for men with hypertension and prostate enlargement. It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls. G - Genito urinary system and sex hormones > G04 - Urologicals > G04C - Drugs used in benign prostatic hypertrophy > G04CA - Alpha-adrenoreceptor antagonists C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D000089162 - Genitourinary Agents > D064804 - Urological Agents
trimebutine
C22H29NO5 (387.20456240000004)
A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03A - Drugs for functional gastrointestinal disorders > A03AA - Synthetic anticholinergics, esters with tertiary amino group D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist D005765 - Gastrointestinal Agents Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects. Target: Opioid Receptor Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain [1]. The major product from drug metabolism of trimebutine in human beings is nor-trimebutine, which comes from removal of one of the methyl groups attached to nitrogen. Trimebutine exerts its effects in part due to causing a premature activation of phase III of the migrating motor complex in the digestive tract [2, 3].
(4-Ethylnaphthalen-1-yl)[1-(5-fluoropentyl)-1H-indol-3-yl]methanone
trimebutine
C22H29NO5 (387.20456240000004)
A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03A - Drugs for functional gastrointestinal disorders > A03AA - Synthetic anticholinergics, esters with tertiary amino group D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist D005765 - Gastrointestinal Agents Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects. Target: Opioid Receptor Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain [1]. The major product from drug metabolism of trimebutine in human beings is nor-trimebutine, which comes from removal of one of the methyl groups attached to nitrogen. Trimebutine exerts its effects in part due to causing a premature activation of phase III of the migrating motor complex in the digestive tract [2, 3].
Guanfu base I
C22H29NO5 (387.20456240000004)
2-(2-Methoxy-phenyl)-5-oxo-tetrahydro-furan-3-carboyl-lupinine
C22H29NO5 (387.20456240000004)
terazosin
G - Genito urinary system and sex hormones > G04 - Urologicals > G04C - Drugs used in benign prostatic hypertrophy > G04CA - Alpha-adrenoreceptor antagonists C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D000089162 - Genitourinary Agents > D064804 - Urological Agents
Guanfu base Y
C22H29NO5 (387.20456240000004)
Origin: Plant; Formula(Parent): C22H29NO5; Bottle Name:Guan-fu base Y; PRIME Parent Name:Guan-fu base Y; PRIME in-house No.:V0331; SubCategory_DNP: Terpenoid alkaloids, Diterpene alkaloid, Aconitum alkaloid
hexyl 6-aminohexanoate,4-methylbenzenesulfonic acid
C19H33NO5S (387.2079328000001)
[5-(4-methylpiperazine-1-carbonyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-2-yl]boronic acid
C19H26BN3O5 (387.19654160000005)
4-(1-(1-ethoxyethyl)-1h-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7h-pyrrolo(2,3-d)pyrimidine
3,4-dihydro-1H-isoquinolin-2-yl-[1-(6-pyrrol-1-ylpyrimidin-4-yl)piperidin-4-yl]methanone
(9,10,19-Trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-3-yl) acetate
C22H29NO5 (387.20456240000004)
(3Z)-3-[(2E,4E,6R)-1-hydroxy-4-methyl-6-[(3R,4S)-1,4,8-trimethyl-2,9-dioxabicyclo[3.3.1]non-7-en-3-yl]hepta-2,4-dienylidene]pyrrolidine-2,4-dione
C22H29NO5 (387.20456240000004)
9-[2-hydroxy-3-(2-methyl-1-benzimidazolyl)propyl]-6-methyl-3,4-dihydro-2H-carbazol-1-one
6-Amino-5-[2-[4-(2-methoxyphenyl)-1-piperazinyl]-1-oxoethyl]-1,3-dimethylpyrimidine-2,4-dione
4-[(3aS,4S,9bS)-1-[cyclobutyl(oxo)methyl]-4-(hydroxymethyl)-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-c]quinolin-8-yl]benzonitrile
(2S,3S,4S)-3-[4-(cyclohexen-1-yl)phenyl]-4-(hydroxymethyl)-1-(2-pyridin-4-ylacetyl)azetidine-2-carbonitrile
(2R,3R,4S)-3-[4-(1-cyclohexenyl)phenyl]-4-(hydroxymethyl)-1-(1-oxo-2-pyridin-4-ylethyl)-2-azetidinecarbonitrile
(2S,3R,4S)-3-[4-(1-cyclohexenyl)phenyl]-4-(hydroxymethyl)-1-(1-oxo-2-pyridin-4-ylethyl)-2-azetidinecarbonitrile
(2S,3R,4R)-3-[4-(cyclohexen-1-yl)phenyl]-4-(hydroxymethyl)-1-(2-pyridin-4-ylacetyl)azetidine-2-carbonitrile
(2R,3S)-8-(2-fluorophenyl)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
(2S,3R)-8-(2-fluorophenyl)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
(2S,3R)-8-(2-fluorophenyl)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
(2R,3R,4R)-3-[4-(1-cyclohexenyl)phenyl]-4-(hydroxymethyl)-1-(1-oxo-2-pyridin-4-ylethyl)-2-azetidinecarbonitrile
(2R,3S)-8-(2-fluorophenyl)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one
(2R,3S,4S)-3-[4-(1-cyclohexenyl)phenyl]-4-(hydroxymethyl)-1-(1-oxo-2-pyridin-4-ylethyl)-2-azetidinecarbonitrile
[(2S,3R)-3-phenyl-6-(2-pyridinylmethyl)-1-(5-pyrimidinylmethyl)-1,6-diazaspiro[3.3]heptan-2-yl]methanol
[(2R,3R)-3-phenyl-6-(2-pyridinylmethyl)-1-(5-pyrimidinylmethyl)-1,6-diazaspiro[3.3]heptan-2-yl]methanol
(2aR,7R,7aS,7bR)-7b-hydroxy-7-{[(1S,2S,4aR,8aR)-2,4a,8a-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]carbonyl}hexahydrofuro[2,3,4-gh]pyrrolizine-2,6-dione
C22H29NO5 (387.20456240000004)
[(1R)-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-1-yl]methyl 2-(2-methoxyphenyl)-5-oxooxolane-3-carboxylate
C22H29NO5 (387.20456240000004)
[(1S,5R,8R,9R,11R,14S,16S,17R,18S,19S)-9,10,19-trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-3-yl] acetate
C22H29NO5 (387.20456240000004)
[(1S,5R,8R,9R,11R,16S,17R,18S,19S)-9,10,19-trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-3-yl] acetate
C22H29NO5 (387.20456240000004)
stemofoline
C22H29NO5 (387.20456240000004)
A natural product found in Stemona curtisii and Stemona aphylla.
UCS1025 A
C22H29NO5 (387.20456240000004)
An organic heterotricyclic compound that incorporates a lactam and a gamma-lactone as part of the cyclic system which in turn is attached to a (2,4a,8a-trimethyl-octahydronaphthalen-1-yl)carbonyl group at position 7. It is isolated from Acremonium sp. KY4917 and exhibits antibacterial activity.
(R)-Terazosin
(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent α1-adrenoceptor antagonist with Ki values of 6.51 nM, 1.01 nM and 1.97 nM for α1a, α1b and α1d-adrenoceptor, respectively[1].
(S)-Terazosin
(S)-Terazosin is an active S-enantiomer of Terazosin. (S)-Terazosin is a potent and high-affinity α-adrenoceptor antagonist with Ki values of 3.91 nM, 0.79 nM and 1.16 nM for α1a, α1b and α1d-adrenoceptor, respectively. (S)-Terazosin also has high-affinity for α2a, α2B and α2c-adrenoceptor with Ki values of 729 nM, 3.5 nM and 46.4 nM, respectively[1].
5-[(1s,3z,4s,5r,6s,8r,9s)-9-butyl-4-methyl-2,14-dioxa-10-azapentacyclo[6.5.1.0¹,⁵.0⁶,¹⁰.0⁹,¹³]tetradecan-3-ylidene]-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
5-[(1s,3e,4s,5r,6s,8s,9s,13r)-9-butyl-4-methyl-2,14-dioxa-10-azapentacyclo[6.5.1.0¹,⁵.0⁶,¹⁰.0⁹,¹³]tetradecan-3-ylidene]-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
(4z)-5-hydroxy-4-[(2e,6r)-1-hydroxy-4-methyl-6-[(1r,3r,4s,5r)-1,4,8-trimethyl-2,9-dioxabicyclo[3.3.1]non-7-en-3-yl]hepta-2,4-dien-1-ylidene]-2h-pyrrol-3-one
C22H29NO5 (387.20456240000004)
(1s,5r)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octan-6-yl (2e)-2-methylbut-2-enoate
C22H29NO5 (387.20456240000004)
2,6,18-trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁷,¹⁶.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-3-yl acetate
C22H29NO5 (387.20456240000004)
5-[(1s,3s,4r,5s,6z,10r,13r)-13-butyl-5-methyl-7,14-dioxa-12-azatetracyclo[8.3.1.0³,¹².0⁴,⁸]tetradec-8-en-6-ylidene]-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
3,6,19-trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁷,¹⁶.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-10-yl acetate
C22H29NO5 (387.20456240000004)
3-({2-[(1-hydroxy-4-methylhexa-2,4-dien-1-ylidene)amino]-3-phenylbutanoyl}oxy)-2-methylbutanoic acid
C22H29NO5 (387.20456240000004)
5-{9-butyl-4-methyl-2,14-dioxa-10-azapentacyclo[6.5.1.0¹,⁵.0⁶,¹⁰.0⁹,¹³]tetradecan-3-ylidene}-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
(1r,4r,5r,8r,9s,10s,11r,14r,16r,17s,18r,19r)-4,16,19-trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁷,¹⁶.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-10-yl acetate
C22H29NO5 (387.20456240000004)
4,16,19-trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁷,¹⁶.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-10-yl acetate
C22H29NO5 (387.20456240000004)
9,10,19-trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁷,¹⁶.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-3-yl acetate
C22H29NO5 (387.20456240000004)
5-[(1r,3z,4s,5r,6s,8s,9s,13r)-9-butyl-4-methyl-2,14-dioxa-10-azapentacyclo[6.5.1.0¹,⁵.0⁶,¹⁰.0⁹,¹³]tetradecan-3-ylidene]-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
5-[(1s,3s,4r,5r,6z,10r,13r)-13-butyl-5-methyl-7,14-dioxa-12-azatetracyclo[8.3.1.0³,¹².0⁴,⁸]tetradec-8-en-6-ylidene]-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
5-[(3e)-9-butyl-4-methyl-2,14-dioxa-10-azapentacyclo[6.5.1.0¹,⁵.0⁶,¹⁰.0⁹,¹³]tetradecan-3-ylidene]-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octan-6-yl (2e)-2-methylbut-2-enoate
C22H29NO5 (387.20456240000004)
5-[(1s,3e,4s,5s,6s,8s,9s,13r)-9-butyl-4-methyl-2,14-dioxa-10-azapentacyclo[6.5.1.0¹,⁵.0⁶,¹⁰.0⁹,¹³]tetradecan-3-ylidene]-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
(4z)-5-hydroxy-4-[(2e,4e,6r)-1-hydroxy-4-methyl-6-[(1r,3r,4s,5r)-1,4,8-trimethyl-2,9-dioxabicyclo[3.3.1]non-7-en-3-yl]hepta-2,4-dien-1-ylidene]-2h-pyrrol-3-one
C22H29NO5 (387.20456240000004)
(1s,3s,5r,8s,9r,10s,11r,14r,16s,17r,18s,19s)-9,10,19-trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁷,¹⁶.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-3-yl acetate
C22H29NO5 (387.20456240000004)
5-hydroxy-4-(1-hydroxy-4-methyl-6-{1,4,8-trimethyl-2,9-dioxabicyclo[3.3.1]non-7-en-3-yl}hepta-2,4-dien-1-ylidene)-2h-pyrrol-3-one
C22H29NO5 (387.20456240000004)
5-{13-butyl-5-methyl-7,14-dioxa-12-azatetracyclo[8.3.1.0³,¹².0⁴,⁸]tetradec-8-en-6-ylidene}-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
1-[(4,5-dimethoxy-2-methylphenyl)methyl]-5,6,7-trimethoxy-1,2,3,4-tetrahydroisoquinoline
C22H29NO5 (387.20456240000004)
5-hydroxy-4-[(6r)-1-hydroxy-4-methyl-6-[(1r,3r,4s,5r)-1,4,8-trimethyl-2,9-dioxabicyclo[3.3.1]non-7-en-3-yl]hepta-2,4-dien-1-ylidene]-2h-pyrrol-3-one
C22H29NO5 (387.20456240000004)
(1s)-1-[(4,5-dimethoxy-2-methylphenyl)methyl]-5,6,7-trimethoxy-1,2,3,4-tetrahydroisoquinoline
C22H29NO5 (387.20456240000004)
(2e,4e,6e,8e,10z)-1-[(1s,4s,5r)-2,4-dihydroxy-4-(2-hydroxyethyl)-6-oxa-3-azabicyclo[3.1.0]hex-2-en-1-yl]-2,6,8,10-tetramethyldodeca-2,4,6,8,10-pentaen-1-one
C22H29NO5 (387.20456240000004)
(2r,3r)-3-{[(2s,3r)-2-{[(2e,4e)-1-hydroxy-4-methylhexa-2,4-dien-1-ylidene]amino}-3-phenylbutanoyl]oxy}-2-methylbutanoic acid
C22H29NO5 (387.20456240000004)
5-[(1s,3s,4r,5s,6e,10r,13r)-13-butyl-5-methyl-7,14-dioxa-12-azatetracyclo[8.3.1.0³,¹².0⁴,⁸]tetradec-8-en-6-ylidene]-4-methoxy-3-methylfuran-2-one
C22H29NO5 (387.20456240000004)
16-ethyl-12-methyl-8-(4-methyl-5-oxooxolan-2-yl)-14-oxa-7-azatetracyclo[8.6.0.0¹,⁷.0¹¹,¹⁵]hexadec-10-ene-2,13-dione
C22H29NO5 (387.20456240000004)
(1s,3r,5s,6s,8r,9s,10s,11r,14r,16s,17s,18r,19r)-3,6,19-trihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁷,¹⁶.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-10-yl acetate
C22H29NO5 (387.20456240000004)