Exact Mass: 377.1506104
Exact Mass Matches: 377.1506104
Found 137 metabolites which its exact mass value is equals to given mass value 377.1506104
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Imidaprilat
Imidaprilat, is the active metabolite of Imidapril. Imidapril is a prodrug used to treat hypertension, chronic congestive heart failure (CHF), acute myocardial infarction (AMI), and diabetic nephropathy (PMID: 17547476,18192036,12177688, 17094051). Imidapril belongs to a class of long-acting, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitors (PMID: 8851752, 12177688). Imidaprilat competitively binds and inhibits the catalytic activity of ACE, which results in a reduction of peripheral resistance and a reduction in systemic blood pressure (BP) (PMID: 17547476). Imidaprilat is only found in individuals that have used or taken imidapril. D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor
Reduced haloperidol
Reduced haloperidol is a metabolite of haloperidol. Haloperidol is a typical antipsychotic. It is in the butyrophenone class of antipsychotic medications and has pharmacological effects similar to the phenothiazines. Haloperidol is an older antipsychotic used in the treatment of schizophrenia and acute psychotic states and delirium. (Wikipedia)
3-(2-(N-(1-Carboxy-3-phenylpropyl)amino)propionyl)-1-methyl-2-oxoimidazolidine-4-carboxylic acid
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors
3-[2-(4-Fluorophenyl)ethylamino]-1-methyl-4-(2-methyl-1H-indol-3-yl)pyrrole-2,5-dione
bruceolline K
An indole alkaloid that is 1,2,3,4-tetrahydrocyclopenta[b]indole substituted by geminal-methyl groups at position 3, an oxo group at position 1 and a beta-D-glucopyranosyloxy group at position 2.It has been isolated from the ethanol extract of the stems of Brucea mollis.
Phentolamine mesilate
C18H23N3O4S (377.14091980000006)
Phentolamine mesylate (Phentolamine methanesulfonate) is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptor that expands blood vessels to reduce peripheral vascular resistance. Phentolamine mesylate can be used for the research of pheochromocytoma-related hypertension, heart failure and erectile dysfunction[1][2][3].
Ala Asn Ser Ser
Ala Ser Asn Ser
Ala Ser Ser Asn
Gly Asn Ser Thr
Gly Asn Thr Ser
Gly Gln Ser Ser
Gly Ser Asn Thr
Gly Ser Gln Ser
Gly Ser Ser Gln
Gly Ser Thr Asn
Gly Thr Asn Ser
Gly Thr Ser Asn
Asn Ala Ser Ser
Asn Gly Ser Thr
Asn Gly Thr Ser
Asn Ser Ala Ser
Asn Ser Gly Thr
Asn Ser Ser Ala
Asn Ser Thr Gly
Asn Thr Gly Ser
Asn Thr Ser Gly
Gln Gly Ser Ser
Gln Ser Gly Ser
Gln Ser Ser Gly
Ser Ala Asn Ser
Ser Ala Ser Asn
Ser Gly Asn Thr
Ser Gly Gln Ser
Ser Gly Ser Gln
Ser Gly Thr Asn
Ser Asn Ala Ser
Ser Asn Gly Thr
Ser Asn Ser Ala
Ser Asn Thr Gly
Ser Gln Gly Ser
Ser Gln Ser Gly
Ser Ser Ala Asn
Ser Ser Gly Gln
Ser Ser Asn Ala
Ser Ser Gln Gly
Ser Thr Gly Asn
Ser Thr Asn Gly
Thr Gly Asn Ser
Thr Gly Ser Asn
Thr Asn Gly Ser
Thr Asn Ser Gly
Thr Ser Gly Asn
Thr Ser Asn Gly
Imidaprilat
A member of the class of imidazolidines that is imidapril in which the ethyl ester group has been hydrolysed to the corresponding acid group. It is the active metabolite of imidapril used to treat hypertension. D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor
3-(4-Methoxybenzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridinehydrochloride
C19H25BClNO4 (377.1565070000001)
1-(4-nitrophenyl)-1,2,2-triphenylethylene
C26H19NO2 (377.14157140000003)
(4-(N-Butyl-N-(4-methoxybenzyl)sulfamoyl)phenyl)boronic acid
C18H24BNO5S (377.14681640000003)
tert-Butyl 5-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate
C19H25BClNO4 (377.1565070000001)
tert-Butyl 7-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate
C19H25BClNO4 (377.1565070000001)
tert-Butyl 6-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate
C19H25BClNO4 (377.1565070000001)
(4-(N-(tert-Butyl)-N-(4-methoxybenzyl)sulfamoyl)phenyl)boronic acid
C18H24BNO5S (377.14681640000003)
7-Pyridin-2-Yl-N-(3,4,5-Trimethoxyphenyl)-7h-Pyrrolo[2,3-D]pyrimidin-2-Amine
C20H19N5O3 (377.1487824000001)
[4-({5-(Aminocarbonyl)-4-[(3-Methylphenyl)amino]pyrimidin-2-Yl}amino)phenyl]acetic Acid
C20H19N5O3 (377.1487824000001)
Phentolamine mesylate
C18H23N3O4S (377.14091980000006)
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents Phentolamine mesylate (Phentolamine methanesulfonate) is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptor that expands blood vessels to reduce peripheral vascular resistance. Phentolamine mesylate can be used for the research of pheochromocytoma-related hypertension, heart failure and erectile dysfunction[1][2][3].
1-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]-N-(5-methyl-2-pyridinyl)-4-piperidinecarboxamide
C17H23N5O3S (377.15215280000007)
1-[4-(3,4,5-Trimethoxyphenyl)-2-thiazolyl]-4-piperidinecarboxamide
C18H23N3O4S (377.14091980000006)
1-(2,5-Dimethoxyphenyl)-3-[5-(2-methylpiperidin-1-yl)-1,3,4-thiadiazol-2-yl]urea
C17H23N5O3S (377.15215280000007)
2-cyano-N-(2-furanylmethyl)-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetamide
C20H19N5O3 (377.1487824000001)
1-(3,4-dihydro-1H-isoquinolin-2-yl)-2-[(2-propyl-4-quinazolinyl)thio]ethanone
C22H23N3OS (377.15617480000003)
(15S)-13-[(4-Fluorophenyl)methyl]-10,10-dimethyl-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
(15S)-13-[(2-Fluorophenyl)methyl]-10,10-dimethyl-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
(15R)-13-[(4-Fluorophenyl)methyl]-10,10-dimethyl-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
(15S)-13-[(3-Fluorophenyl)methyl]-10,10-dimethyl-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
(15R)-13-[(2-Fluorophenyl)methyl]-10,10-dimethyl-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
4-[(2E)-2-(2,4,5-trimethoxybenzylidene)hydrazinyl]-5H-pyrimido[5,4-b]indole
C20H19N5O3 (377.1487824000001)
2-[[(1S,5R)-7-[4-(2-methoxyphenyl)phenyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]methyl]thiazole
C22H23N3OS (377.15617480000003)
(8aR)-2-(1-benzothiophen-2-ylmethyl)-7-benzyl-5,6,8,8a-tetrahydro-1H-imidazo[1,5-a]pyrazin-3-one
C22H23N3OS (377.15617480000003)
2-(2-Trimethylsilyloxyethoxy)-4-quinolinecarboxylic acid trimethylsilyl ester
3-[2-(4-Fluorophenyl)ethylamino]-1-methyl-4-(2-methyl-1H-indol-3-yl)pyrrole-2,5-dione
H3R antagonist 1 (hydrochloride)
H3R antagonist 1 hydrochloride is a histamine receptor 3 (H3R) inverse agonist extracted from patent WO2013107336A1, compound example 2.