Exact Mass: 353.9673716

Exact Mass Matches: 353.9673716

Found 28 metabolites which its exact mass value is equals to given mass value 353.9673716, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Pipobroman

3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one

C10H16Br2N2O2 (353.9578436)

Pipobroman is only found in individuals that have used or taken this drug. It is an antineoplastic agent that acts by alkylation. [PubChem]The mechanism of action is uncertain but pipobroman is thought to alkylate DNA leading to disruption of DNA synthesis and eventual cell death. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents D000970 - Antineoplastic Agents

idoxuridine

C9H11IN2O5 (353.9712706)

J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AB - Nucleosides and nucleotides excl. reverse transcriptase inhibitors D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use > D06BB - Antivirals S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AD - Antivirals D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C274 - Antineoplastic Agent > C798 - Radiosensitizing Agent Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM[1]. Idoxuridine shows anti-orthopoxvirus activity.

Idoxuridine

1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione

C9H11IN2O5 (353.9712706)

Idoxuridine is only found in individuals that have used or taken this drug. It is an analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent. [PubChem]Idoxuridine acts as an antiviral agent by inhibiting viral replication by substituting itself for thymidine in viral DNA. This in turn inhibits thymidylate phosphorylase and viral DNA polymerases from properly functioning. The effect of Idoxuridine results in the inability of the virus to reproduce or to infect/destroy tissue. J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AB - Nucleosides and nucleotides excl. reverse transcriptase inhibitors D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use > D06BB - Antivirals S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AD - Antivirals D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C274 - Antineoplastic Agent > C798 - Radiosensitizing Agent Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM[1]. Idoxuridine shows anti-orthopoxvirus activity.

Dendrid

1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione

C9H11IN2O5 (353.9712706)

5'-Iododeoxyuridine

1-{4-hydroxy-5-[hydroxy(iodo)methyl]oxolan-2-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione

C9H11IN2O5 (353.9712706)

Diphosphoglucuronic acid

2,3,4-trihydroxy-5-{[hydroxy(phosphonooxy)phosphoryl]oxy}-6-oxohexanoic acid

C6H12O13P2 (353.9753162)

(2S,4R,5S)-4,5,6-Trihydroxy-2-[hydroxy(phosphonooxy)phosphoryl]oxy-3-oxohexanoic acid

C6H12O13P2 (353.9753162)

5'-Deoxy-5'-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Uridine, 2-deoxy-5-iodo-

1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-iodopyrimidine-2,4-dione

C9H11IN2O5 (353.9712706)

D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents

2,4-Dihydroxy-3-oxo-5-phosphonooxy-2-(phosphonooxymethyl)pentanoic acid

C6H12O13P2 (353.9753162)

2,3,4-Trihydroxy-5-[hydroxy(phosphonooxy)phosphoryl]oxy-6-oxohexanoic acid

C6H12O13P2 (353.9753162)

(2S,4R,5S)-4,5,6-Trihydroxy-2-[hydroxy(phosphonooxy)phosphoryl]oxy-3-oxohexanoic acid

C6H12O13P2 (353.9753162)

pipobroman

C10H16Br2N2O2 (353.9578436)

L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents D000970 - Antineoplastic Agents

1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-iodopyrimidine-2,4-dione

C9H11IN2O5 (353.9712706)

16-bromo-10-hydroxy-3,5,9,19-tetraazapentacyclo[10.7.0.0²,⁶.0⁷,¹¹.0¹³,¹⁸]nonadeca-1(12),2(6),4,7(11),9,13(18),14,16-octaen-8-one

C15H7BrN4O2 (353.9752342)