Exact Mass: 348.9263

Exact Mass Matches: 348.9263

Found 31 metabolites which its exact mass value is equals to given mass value 348.9263, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Chlorpyrifos

Phosphorothioic acid, O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) ester

C9H11Cl3NO3PS (348.9263)


A study of the effects of chlorpyrifos on humans exposed over time showed that people exposed to high levels have autoimmune antibodies that are common in people with autoimmune disorders. There is a strong correlation to chronic illness associated with autoimmune disorders after exposure to chlorpyrifos. Among 50 farm pesticides studied, chlorpyrifos was one of two found to be associated with higher risks of lung cancer among frequent pesticide applicators than among infrequent or non-users. Pesticide applicators as a whole were found to have a 50\\% lower cancer risk than the general public, which is attributable to the nearly 50\\% lower smoking rate found among farm workers. However, applicators of chlorpyrifos had a 15\\% lower cancer risk than the general public, which the study suggests indicates a likely link between chlorpyrifos application and lung cancer. Chlorpyrifos (IUPAC name: O,O-diethyl O-3,5,6-trichloropyridin-2-yl phosphorothioate) is a crystalline organophosphate insecticide. It was introduced in 1965 by Dow Chemical Company and is known by many trade names (see table), including Dursban and Lorsban. It acts on the nervous system of insects by inhibiting acetylcholinesterase. Chlorpyrifos is an organophosphate, with potential for both acute toxicity at larger amounts and neurological effects in fetuses and children even at very small amounts. For acute effects, the EPA classifies chlorpyrifos as Class II: moderately toxic. The oral LD50 for chlorpyrifos in experimental animals is 32 to 1000 mg/kg. The dermal LD50 in rats is greater than 2000 mg/kg and 1000 to 2000 mg/kg in rabbits. The 4-hour inhalation LC50 for chlorpyrifos in rats is greater than 200 mg/m3. First registered in 1965 and marketed by Dow Chemical under the tradenames Dursban, Lorsban and Renoban, chlorpyrifos was a well known home and garden insecticide, and at one time it was one of the most widely used household pesticides in the US. D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor D010575 - Pesticides > D007306 - Insecticides D004791 - Enzyme Inhibitors D016573 - Agrochemicals

   

Tetrachlorosalicylanilide

2-Hydroxy-3,4,5,6-tetrachlorobenzanilide

C13H7Cl4NO2 (348.9231)


CONFIDENCE standard compound; INTERNAL_ID 2369 D004791 - Enzyme Inhibitors CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8640 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8243

   

3,3',4',5-Tetrachlorosalicylanilide

3,5-dichloro-N-(3,4-dichlorophenyl)-2-hydroxybenzene-1-carboximidic acid

C13H7Cl4NO2 (348.9231)


D004791 - Enzyme Inhibitors

   
   

3,3,4,5-Tetrachlorosalicylanilide

3,3,4,5-Tetrachlorosalicylanilide

C13H7Cl4NO2 (348.9231)


D004791 - Enzyme Inhibitors

   

3-(2-Hydroxyethyl)-3-hydroxy-4,6-dibromoindoline-2-one

3-(2-Hydroxyethyl)-3-hydroxy-4,6-dibromoindoline-2-one

C10H9Br2NO3 (348.8949)


   

Clorpyrifos

chlorpyrifos

C9H11Cl3NO3PS (348.9263)


D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor D010575 - Pesticides > D007306 - Insecticides D004791 - Enzyme Inhibitors D016573 - Agrochemicals CONFIDENCE standard compound; INTERNAL_ID 8177 CASMI2013 Challenge_9 MS2 data; [MS1] MSJ00015 CASMI2013 Challenge_9 MS1 data; [MS2] MSJ00016 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2950

   

6-iodo-2-phenyl-3,1-benzoxazin-4-one

6-iodo-2-phenyl-3,1-benzoxazin-4-one

C14H8INO2 (348.96)


   

5-Bromo-2-(4-bromophenyl)-1H-indole

5-Bromo-2-(4-bromophenyl)-1H-indole

C14H9Br2N (348.9102)


   

2,3-DIBROMOPHENYL N,N-DIETHYLCARBAMATE

2,3-DIBROMOPHENYL N,N-DIETHYLCARBAMATE

C11H13Br2NO2 (348.9313)


   

5-(4-CHLOROBENZAMIDOMETHYL)THIOPHENE-2-SULPHONYL CHLORIDE

5-(4-CHLOROBENZAMIDOMETHYL)THIOPHENE-2-SULPHONYL CHLORIDE

C12H9Cl2NO3S2 (348.9401)


   

4-Iodophenyl 4-cyanobenzoate

4-Iodophenyl 4-cyanobenzoate

C14H8INO2 (348.96)


   

3,6-dibromo-9-ethenylcarbazole

3,6-dibromo-9-ethenylcarbazole

C14H9Br2N (348.9102)


   

2-chloro-N-[(3,4-dichlorophenyl)methyl]benzenesulfonamide

2-chloro-N-[(3,4-dichlorophenyl)methyl]benzenesulfonamide

C13H10Cl3NO2S (348.9498)


   

4-(Dibromomethyl)-[1,1-biphenyl]-2-carbonitrile

4-(Dibromomethyl)-[1,1-biphenyl]-2-carbonitrile

C14H9Br2N (348.9102)


   

3-Iodo-2-phenyl-4H-pyrano[2,3-b]pyridin-4-one

3-Iodo-2-phenyl-4H-pyrano[2,3-b]pyridin-4-one

C14H8INO2 (348.96)


   

N,N-BIS(2,4-DICHLOROBENZYL)HYDROXYLAMINE

N,N-BIS(2,4-DICHLOROBENZYL)HYDROXYLAMINE

C14H11Cl4NO (348.9595)


   

N-(5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-(methylsulfo nyl)acetamide

N-(5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-(methylsulfo nyl)acetamide

C10H9BrFN3O3S (348.9532)


   

Disodium stannous citrate

Disodium stannous citrate

C6H6NaO8Sn (348.8982)


   

2,7-Dibromo-9-vinyl-9H-carbazole

2,7-Dibromo-9-vinyl-9H-carbazole

C14H9Br2N (348.9102)


   

Methyl 8-bromo-4-hydroxy-5-(trifluoromethyl)quinoline-2-carboxylate

Methyl 8-bromo-4-hydroxy-5-(trifluoromethyl)quinoline-2-carboxylate

C12H7BrF3NO3 (348.9561)


   

3,5-Bis(trifluoromethyl)-N-(bromoacetyl)aniline

3,5-Bis(trifluoromethyl)-N-(bromoacetyl)aniline

C10H6BrF6NO (348.9537)


   

4-(Dibromomethyl)-[1,1-Biphenyl]-4-Carbonitrile

4-(Dibromomethyl)-[1,1-Biphenyl]-4-Carbonitrile

C14H9Br2N (348.9102)


   

2,4-Dichloro-5-[(furan-2-ylmethyl)sulfamoyl]benzoic acid

2,4-Dichloro-5-[(furan-2-ylmethyl)sulfamoyl]benzoic acid

C12H9Cl2NO5S (348.9578)


   

4-[4-(2,4-Dichlorophenyl)-2-thiazolyl]benzoic acid

4-[4-(2,4-Dichlorophenyl)-2-thiazolyl]benzoic acid

C16H9Cl2NO2S (348.9731)


   

Perfluoropentane sulfonamide

Perfluoropentane sulfonamide

C5H2F11NO2S (348.9631)


   

2-carboxy-3-keto-D-arabinitol-1,5-bisphosphate

2-carboxy-3-keto-D-arabinitol-1,5-bisphosphate

C6H7O13P2-5 (348.9362)


   

(R)-CE3F4

(R)-CE3F4

C11H10Br2FNO (348.9113)


(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1].

   

CE3F4

CE3F4

C11H10Br2FNO (348.9113)


CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1), with IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively.

   

4,6-dibromo-3-(2-hydroxyethyl)indole-2,3-diol

4,6-dibromo-3-(2-hydroxyethyl)indole-2,3-diol

C10H9Br2NO3 (348.8949)


   

(3r)-4,6-dibromo-3-(2-hydroxyethyl)indole-2,3-diol

(3r)-4,6-dibromo-3-(2-hydroxyethyl)indole-2,3-diol

C10H9Br2NO3 (348.8949)