Exact Mass: 338.1518012

Exact Mass Matches: 338.1518012

Found 142 metabolites which its exact mass value is equals to given mass value 338.1518012, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

Bergamottin

7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-

C21H22O4 (338.1518012)


Bergomottin is a furanocoumarin. It has a role as a metabolite. Bergamottin is a natural product found in Hansenia forbesii, Citrus hystrix, and other organisms with data available. See also: Lime (Citrus) (part of). D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins A natural product found in Citrus hystrix. Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM. Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.

   

6-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-2-(2-phenylethenyl)benzoic acid

6-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-2-[(E)-2-phenylethenyl]benzoic acid

C21H22O4 (338.1518012)


6-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-2-(2-phenylethenyl)benzoic acid is found in pigeon pea. 6-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-2-(2-phenylethenyl)benzoic acid is a constituent of Cajanus cajan (pigeon pea). Constituent of Cajanus cajan (pigeon pea). 6-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-2-(2-phenylethenyl)benzoic acid is found in pigeon pea and pulses.

   

2,2,4-Trimethyl-3-(4-methoxyphenyl)-2H-1-benzopyran-7-ol acetate

2,2,4-Trimethyl-3-(4-methoxyphenyl)-2H-1-benzopyran-7-ol acetate

C21H22O4 (338.1518012)


   

9-[(3,7-Dimethyl-2,6-octadienyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one

7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-

C21H22O4 (338.1518012)


9-[(3,7-Dimethyl-2,6-octadienyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one is a terpene lactone. Xanthotoxol geranyl ether is a natural product found in Citrus garrawayi, Skimmia laureola, and other organisms with data available. 9-[(3,7-Dimethyl-2,6-octadienyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one is found in citrus. 9-[(3,7-Dimethyl-2,6-octadienyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one is a constituent of lemon oil. D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins Constituent of lemon oil. Xanthotoxol geranyl ether is found in lemon and citrus. 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM[1]. 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM[1].

   

Licochalcone A

3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one, 9ci

C21H22O4 (338.1518012)


Licochalcone A is found in herbs and spices. Licochalcone A is a constituent of the roots of Glycyrrhiza glabra (licorice)

   

2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-6-(2-phenylethenyl)benzoic acid

2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-[(E)-2-phenylethenyl]benzoic acid

C21H22O4 (338.1518012)


2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-6-(2-phenylethenyl)benzoic acid is found in pulses. 2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-6-(2-phenylethenyl)benzoic acid is a constituent of Cajanus cajan (pigeon pea). Constituent of Cajanus cajan (pigeon pea). 2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-6-(2-phenylethenyl)benzoic acid is found in pulses. D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates

   

Bergamottin

4-[(3,7-Dimethyl-2,6-octadienyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one, 9ci

C21H22O4 (338.1518012)


Bergamottin is found in citrus. Bergamottin is a constituent of bergamot oil. Also from lemon oil and oils of other Citrus species and carrot (Daucus carota) Bergamottin is a natural furanocoumarin found principally in grapefruit juice. It is also found in the oil of bergamot, from which it was first isolated and from which its name is derived. To a lesser extent, bergamottin is also present in the essential oils of other citrus fruits. Along with the chemically related compound 6 ,7 -dihydroxybergamottin, it is believed to be responsible for the grapefruit juice effect in which the consumption of the juice affects the metabolism of a variety of pharmaceutical drugs Constituent of bergamot oiland is also from lemon oil and oils of other Citrus subspecies and carrot (Daucus carota) Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM. Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.

   

Licoagrocarpin

14-methoxy-6-(3-methylbut-2-en-1-yl)-8,17-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁶]heptadeca-2(7),3,5,11(16),12,14-hexaen-5-ol

C21H22O4 (338.1518012)


Licoagrocarpin is found in herbs and spices. Licoagrocarpin is isolated from the hairy root cultures of Glycyrrhiza glabra (licorice

   

2'-O-Methylglabridin

4-{12,12-dimethyl-3,11-dioxatricyclo[8.4.0.0²,⁷]tetradeca-1(10),2(7),8,13-tetraen-5-yl}-3-methoxyphenol

C21H22O4 (338.1518012)


2-O-Methylglabridin is found in herbs and spices. 2-O-Methylglabridin is isolated from Glycyrrhiza glabra (licorice). Isolated from Glycyrrhiza glabra (licorice). 2-O-Methylglabridin is found in tea and herbs and spices.

   

Gancaonin X

2-{13,13-dimethyl-4,14-dioxatricyclo[8.4.0.0³,⁸]tetradeca-1(10),2,8,11-tetraen-6-yl}-5-methoxyphenol

C21H22O4 (338.1518012)


Gancaonin X is found in herbs and spices. Gancaonin X is a constituent of Glycyrrhiza uralensis (Chinese licorice). Constituent of Glycyrrhiza uralensis (Chinese licorice). Gancaonin X is found in herbs and spices.

   

Orientanol B

5-methoxy-4-(3-methylbut-2-en-1-yl)-8,17-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁶]heptadeca-2(7),3,5,11(16),12,14-hexaen-14-ol

C21H22O4 (338.1518012)


Orientanol B is found in green vegetables. Orientanol B is a constituent of Erythrina glauca (gallito)

   

4'-O-Methylglabridin

2-{12,12-dimethyl-3,11-dioxatricyclo[8.4.0.0²,⁷]tetradeca-1(10),2(7),8,13-tetraen-5-yl}-5-methoxyphenol

C21H22O4 (338.1518012)


4-O-Methylglabridin is found in herbs and spices. 4-O-Methylglabridin is isolated from Glycyrrhiza glabra (licorice). Isolated from Glycyrrhiza glabra (licorice). 4-O-Methylglabridin is found in tea and herbs and spices.

   

Archangelin

4-[(2,4,4-Trimethyl-1-cyclohexen-1-yl)methoxy]-7H-furo[3,2-g][1]benzopyran-7-one, 9ci

C21H22O4 (338.1518012)


Archangelin is found in fats and oils. Archangelin is a constituent of the root of Angelica archangelica (angelica)

   

2'-O-Methylphaseollinisoflavan

3-(5-methoxy-1,1-dimethyl-1H-isochromen-6-yl)-3,4-dihydro-2H-1-benzopyran-7-ol

C21H22O4 (338.1518012)


From Phaseolus vulgaris (kidney bean). 2-O-Methylphaseollinisoflavan is found in many foods, some of which are common bean, pulses, green bean, and yellow wax bean. 2-O-Methylphaseollinisoflavan is found in common bean. 2-O-Methylphaseollinisoflavan is from Phaseolus vulgaris (kidney bean

   

4-Hydroxyderricin

1-[2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one

C21H22O4 (338.1518012)


   

7-O-Methylbavachin

2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one

C21H22O4 (338.1518012)


   

Bergaptin

4-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one

C21H22O4 (338.1518012)


   

LicochalconeC

Licochalcone CEvocarpineDamulin BPonicidinAcanthoside BKumatakeninCyclovirobuxine DPseudohypericin

C21H22O4 (338.1518012)


Licochalcone C is a natural product found in Glycyrrhiza glabra and Glycyrrhiza inflata with data available. Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

   

O-Methylbroussochalcone B

2-Propen-1-one, 1-[2-hydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-

C21H22O4 (338.1518012)


(2e)-1-[2-Hydroxy-4-Methoxy-5-(3-Methylbut-2-En-1-Yl)phenyl]-3-(4-Hydroxyphenyl)prop-2-En-1-One is a natural product found in Cullen corylifolium and Sophora prostrata with data available. 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM[1]. 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM[1].

   

Licochalcone_A

2-PROPEN-1-ONE, 3-(5-(1,1-DIMETHYL-2-PROPENYL)-4-HYDROXY-2-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-, (2E)-

C21H22O4 (338.1518012)


Licochalcone A is a member of chalcones. Licochalcone a is a natural product found in Euphorbia helioscopia, Pogostemon cablin, and other organisms with data available. Licochalcone A is a derivative of the phenol chalconoid, found in and extracted from the roots of Glycyrrhiza species G. glabra and inflata, with potential anti-inflammatory, antibacterial, and anticancer activities. Upon administration, licochalcone A inhibits the phosphatidylinositol-3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathway and inhibits the activity of c-Jun N-terminal kinase 1 (JNK-1), a member of the mitogen-activated protein kinase (MAPK) family that plays a role in the MAPK-mediated signaling pathway. Inhibition of the PI3K/Akt/mTOR- and MAPK-signaling pathways induces cell cycle arrest and apoptosis, decreases migration and invasion of cancer cells, and inhibits tumor cell proliferation. Licochalcone A also prevents the production of reactive oxygen species (ROS), and reduces oxidative stress through the nuclear factor-erythroid 2-related factor 2 (Nrf2) pathway. C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor

   

Bavachinin

4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-, (2S)-

C21H22O4 (338.1518012)


Bavachinin is a member of flavanones. Bavachinin is a natural product found in Cullen corylifolium with data available. See also: Cullen corylifolium fruit (part of). Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5]. Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5]. Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5]. Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5].

   

Licochalcone E

(E)-3-[4-hydroxy-2-methoxy-5-[(2S)-3-methylbut-3-en-2-yl]phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

C21H22O4 (338.1518012)


Licochalcone E is a natural product found in Glycyrrhiza inflata with data available.

   

Licochalcone

2-Propen-1-one, 3-(4-hydroxy-2-methoxy-3-(3-methyl-2-butenyl)phenyl)-1-(4-hydroxyphenyl)-, (2E)-

C21H22O4 (338.1518012)


Licochalcone C is a natural product found in Glycyrrhiza glabra and Glycyrrhiza inflata with data available. Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

   
   

Burttinol A

7,4-Dihydroxy-2-methoxy-6-(1,1-dimethyl-2-propenyl)isoflav-3-ene

C21H22O4 (338.1518012)


   

Gancaonin Y

7-Hydroxy-4-methoxy-6,6-dimethylpyrano[2,3:2,3]isoflavan

C21H22O4 (338.1518012)


   
   

Burttinol C

7,4-Dihydroxy-2-methoxy-8-prenylisoflav-3-ene

C21H22O4 (338.1518012)


   

5-Hydroxy-7-methoxy-6-C-prenylflavanone

5-Hydroxy-7-methoxy-6-C-prenylflavanone

C21H22O4 (338.1518012)


   

7-O-Prenylcryptostrobin

5-Hydroxy-7-prenyloxy-8-C-methylflavanone

C21H22O4 (338.1518012)


   

6-C-Prenyl-8-C-methylpinocembrin

5,7-Dihydroxy-6-C-prenyl-8-C-methylflavanone

C21H22O4 (338.1518012)


   
   

5,7-Dihydroxy-6-methyl-8-prenylflavanone

5,7-Dihydroxy-6-methyl-8-prenylflavanone

C21H22O4 (338.1518012)


   
   

Tephrinone

5-Hydroxy-7-methoxy-8-C-prenylflavanone

C21H22O4 (338.1518012)


   
   

Hildgardtol A

8,9-Dihydro-4-hydroxy-8-isopropenyl-5-methoxyfurano [ 2,3-h ] flavan

C21H22O4 (338.1518012)


   

Prostratol D

(6aR,11aR)-3-Hydroxy-9-methoxy-8-prenylpterocarpan

C21H22O4 (338.1518012)


   

Falciformin

(2S)-2,3-Dihydro-5-(2-hydroxy-1,1-dimethyl-2-propen-1-yl)-6-methoxy-2-phenyl-4H-1-benzopyran-4-one

C21H22O4 (338.1518012)


   

5-Methoxy-7-prenyloxyflavanone

5-Methoxy-7-prenyloxyflavanone

C21H22O4 (338.1518012)


   

Isoxanthohumol(Helichrysum)

(E) -2,6-Dihydroxy-4-methoxy-3- (3-methyl-2-butenyl) chalcone

C21H22O4 (338.1518012)


   

Licochalcone C

(E) -4,4-Dihydroxy-6-methoxy-5- (3-methyl-2-butenyl) chalcone

C21H22O4 (338.1518012)


Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

   

Bavachalcone

1- [ 2-Hydroxy-4-methoxy-5- (3-methyl-2-butenyl) phenyl ] -3- (4-hydroxyphenyl) -2-propen-1-one

C21H22O4 (338.1518012)


4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM[1]. 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM[1].

   

2,4-Dihydroxy-6-methoxy-3-prenylchalcone

2,4-Dihydroxy-6-methoxy-3-prenylchalcone

C21H22O4 (338.1518012)


   

2-Hydroxy-6-methoxy-4-prenyloxychalcone

2-Hydroxy-6-methoxy-4-prenyloxychalcone

C21H22O4 (338.1518012)


   

1,7-Bis(4-hydroxyphenyl)-1-heptene-3,5-dione

1,7-Bis(4-hydroxyphenyl)-1-heptene-3,5-dione

C21H22O4 (338.1518012)


   

orientanol B

3-O-Methylcalopocarpin

C21H22O4 (338.1518012)


   

Mundulea flavanone A

4-Hydroxy-7-methoxy-8-prenylflavanone

C21H22O4 (338.1518012)


   

4-Hydroxyderricin

(E) -1- [ 2-Hydroxy-4-methoxy-3- (3-methyl-2-butenyl) phenyl ] -3- (4-hydroxyphenyl) -2-propen-1-one

C21H22O4 (338.1518012)


4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity[1]. 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity[1].

   

Sandwicensin

(6aR,11aR) -9-Methoxy-10- (3-methylbut-2-enyl) -6a,11a-dihydro-6H- [1] benzofuro [3,2-c] chromen-3-ol

C21H22O4 (338.1518012)


A member of the class of pterocarpans that is (6aR,11aR)-pterocarpan substituted by a hydroxy group at position 3, a methoxy group at position 9 and a prenyl group at position 10. Isolated from Erythrina glauca and Erythrina stricta, it exhibits anti-HIV-1 activity.

   

Crotaramin

1- (5-Hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl) -3- (4-methoxyphenyl) -1-propanone

C21H22O4 (338.1518012)


   

4-O-Methylglabridin

2- [ [ (R) -3,4-Dihydro-8,8-dimethyl-2H,8H-benzo [ 1,2-b:3,4-b ] dipyran ] -3beta-yl ] -5-methoxyphenol

C21H22O4 (338.1518012)


   

2-O-Methylphaseollinisoflavan

2-O-Methylphaseollinisoflavan

C21H22O4 (338.1518012)


A methoxyisoflavan that is the 2-O-methyl derivative of (-)-phaseollinisoflavan.

   

3-[4-hydroxy-2-methoxy-3-(3-methylbut-2-enyl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

3-[4-hydroxy-2-methoxy-3-(3-methylbut-2-enyl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

C21H22O4 (338.1518012)


   

2-(3,4-dimethoxyphenyl)-7-methoxy-3-methyl-5-prop-1-enyl-1-benzofuran

2-(3,4-dimethoxyphenyl)-7-methoxy-3-methyl-5-prop-1-enyl-1-benzofuran

C21H22O4 (338.1518012)


   

5,6-Dihydro-11-methoxy-2,2,12-trimethyl-2H-phenanthro[2,1-b]pyran-8,9-diol

5,6-Dihydro-11-methoxy-2,2,12-trimethyl-2H-phenanthro[2,1-b]pyran-8,9-diol

C21H22O4 (338.1518012)


   

Garugamblin 1|garugamblin I|garugamblin-1

Garugamblin 1|garugamblin I|garugamblin-1

C21H22O4 (338.1518012)


   

2,6-dihydroxy-4-methoxy-3-C-prenylchalcone|Isoxanthohumol

2,6-dihydroxy-4-methoxy-3-C-prenylchalcone|Isoxanthohumol

C21H22O4 (338.1518012)


   

7-O-prenylstrobopinin

7-O-prenylstrobopinin

C21H22O4 (338.1518012)


   

2-Me ether,4-O-(3-methyl-2-butenyl)-2,4,6-Trihydroxychalcone

2-Me ether,4-O-(3-methyl-2-butenyl)-2,4,6-Trihydroxychalcone

C21H22O4 (338.1518012)


   
   

2,4-Dihydroxy-6-methoxy-3-prenylchalcone|isoxanthohumol

2,4-Dihydroxy-6-methoxy-3-prenylchalcone|isoxanthohumol

C21H22O4 (338.1518012)


   
   

(E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one

(E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one

C21H22O4 (338.1518012)


   

5-Allyl-2-(3,4-dimethoxyphenyl)-7-methoxy-3-methylbenzofuran

5-Allyl-2-(3,4-dimethoxyphenyl)-7-methoxy-3-methylbenzofuran

C21H22O4 (338.1518012)


   
   

14-(Angeloyloxy)dehydrocacalohastin

14-(Angeloyloxy)dehydrocacalohastin

C21H22O4 (338.1518012)


   

12-epi-conycephaloide

12-epi-conycephaloide

C21H22O4 (338.1518012)


   

4,5-dimethoxy-3,4-methylenedioxy-2,7-cyclolign-7-ene|pycnanthulignene B

4,5-dimethoxy-3,4-methylenedioxy-2,7-cyclolign-7-ene|pycnanthulignene B

C21H22O4 (338.1518012)


   
   

5,7-Dihydroxy-2-(6-phenylhexyl)-gamma-chromene-4-one

5,7-Dihydroxy-2-(6-phenylhexyl)-gamma-chromene-4-one

C21H22O4 (338.1518012)


   
   

9-(3,7-dimethyl-2,6-octadienyl)-4-hydroxy-7H-furo[3,2-gamma][1]benzopyran-7-one

9-(3,7-dimethyl-2,6-octadienyl)-4-hydroxy-7H-furo[3,2-gamma][1]benzopyran-7-one

C21H22O4 (338.1518012)


   

(2E)-1-(4-hydroxyphenyl)-3-{2-methoxy-4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-en-1-one|4-hydroxy-2-methoxy-4-prenyloxychalcone|xinjiachalcone A

(2E)-1-(4-hydroxyphenyl)-3-{2-methoxy-4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-en-1-one|4-hydroxy-2-methoxy-4-prenyloxychalcone|xinjiachalcone A

C21H22O4 (338.1518012)


   
   

Bauhinoxepin B

Bauhinoxepin B

C21H22O4 (338.1518012)


A dibenzooxepine that is dibenzo[b,f]oxepine substituted by a methoxy group at position 6, a methyl group at position 7, a prenyl group at position 2 and hydroxy groups at positions 1 and 8 respectively. It is isolated from the roots of Bauhinia saccocalyx and exhibits antimycobacterial activity.

   
   
   

neopetrosiquinone B

neopetrosiquinone B

C21H22O4 (338.1518012)


   

helichromanochalcone

helichromanochalcone

C21H22O4 (338.1518012)


   

2,5-bis-(3,4-methylenedioxiphenyl)-3,4-dimethyltetrahydrofuran

2,5-bis-(3,4-methylenedioxiphenyl)-3,4-dimethyltetrahydrofuran

C21H22O4 (338.1518012)


   

(2S)-7-hydroxy-5-methoxy-8-prenylflavanone

(2S)-7-hydroxy-5-methoxy-8-prenylflavanone

C21H22O4 (338.1518012)


   
   
   

2-(3-methyl-1-butenyl)-1,8-dihydroxy-3-methoxy-6-methylanthrone

2-(3-methyl-1-butenyl)-1,8-dihydroxy-3-methoxy-6-methylanthrone

C21H22O4 (338.1518012)


   

5-(Geranyloxy)psoralen|5-Geranoxy-psoralen

5-(Geranyloxy)psoralen|5-Geranoxy-psoralen

C21H22O4 (338.1518012)


   

lespeflorin G10

lespeflorin G10

C21H22O4 (338.1518012)


A member of the class of pterocarpans that is (6aR,11aR)-pterocarpan substituted by hydroxy groups at positions 3 and 9, a methyl group at position 8 and a prenyl group at position 10. Isolated from the roots of Lespedeza floribunda, it acts as a melanin synthesis inhibitor.

   

2,3-dihydro-8-(3-hydroxy-3-methylbut-1-enyl)-7-methoxy-2-phenyl-4H-1-benzopyran-4-one|Falciformin

2,3-dihydro-8-(3-hydroxy-3-methylbut-1-enyl)-7-methoxy-2-phenyl-4H-1-benzopyran-4-one|Falciformin

C21H22O4 (338.1518012)


   

2-Prenylphyscion anthrone

2-Prenylphyscion anthrone

C21H22O4 (338.1518012)


   

9-((2,5,5-trimethylcyclohex-1-enyl)methoxy)-7H-furo[3,2-g]chromen-7-one

9-((2,5,5-trimethylcyclohex-1-enyl)methoxy)-7H-furo[3,2-g]chromen-7-one

C21H22O4 (338.1518012)


   

Delta7-3,4-Dimethoxy-3,4-methylenedioxy-6.7,8.8-neolignan

Delta7-3,4-Dimethoxy-3,4-methylenedioxy-6.7,8.8-neolignan

C21H22O4 (338.1518012)


   
   

2-Methylteretifolione B|8-C-methyl-teretifolione B

2-Methylteretifolione B|8-C-methyl-teretifolione B

C21H22O4 (338.1518012)


   
   
   
   

(2S)-2,6-bis(p-hydroxyphenethyl)-2,3-dihydropyran-4-one|(3S)-3,7-anhydro-6,7-dehydroericanone

(2S)-2,6-bis(p-hydroxyphenethyl)-2,3-dihydropyran-4-one|(3S)-3,7-anhydro-6,7-dehydroericanone

C21H22O4 (338.1518012)


   

4-methoxylonchocarpin

4-methoxylonchocarpin

C21H22O4 (338.1518012)


   
   

Xinjiachalcone A

(E)-1-(4-hydroxyphenyl)-3-[2-methoxy-4-(3-methylbut-2-enoxy)phenyl]prop-2-en-1-one

C21H22O4 (338.1518012)


   

4-Hydroxyderricin

2-Propen-1-one, 1-[2-hydroxy-4-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-

C21H22O4 (338.1518012)


4-Hydroxyderricin is a member of chalcones. 4-Hydroxyderricin is a natural product found in Angelica keiskei, Millettia dura, and Sophora prostrata with data available. See also: Angelica keiskei top (part of); Angelica keiskei root (part of). 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity[1]. 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity[1].

   

bergamottin

bergamottin

C21H22O4 (338.1518012)


relative retention time with respect to 9-anthracene Carboxylic Acid is 1.538 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.539 Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM. Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.

   

8-Geranyloxy psoralen

8-Geranyloxy psoralen

C21H22O4 (338.1518012)


relative retention time with respect to 9-anthracene Carboxylic Acid is 1.451 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.448

   

(E)-3-[2,4-dihydroxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one

NCGC00380083-01!(E)-3-[2,4-dihydroxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one

C21H22O4 (338.1518012)


   

(2S)-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

NCGC00163517-02!(2S)-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

C21H22O4 (338.1518012)


   

bavachinin A

bavachinin A

C21H22O4 (338.1518012)


Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5]. Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5]. Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5]. Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5].

   

Chalcone base + 2O, 1MeO, 1Prenyl

Chalcone base + 2O, 1MeO, 1Prenyl

C21H22O4 (338.1518012)


Annotation level-3

   

Chalcone base + 2O, 1MeO, 1Prenyl or Licochalcone A (Not validated)

Chalcone base + 2O, 1MeO, 1Prenyl or Licochalcone A (Not validated)

C21H22O4 (338.1518012)


Annotation level-3

   

(E)-3-[2,4-dihydroxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one [IIN-based: Match]

NCGC00380083-01!(E)-3-[2,4-dihydroxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one [IIN-based: Match]

C21H22O4 (338.1518012)


   

(E)-3-[2,4-dihydroxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one [IIN-based on: CCMSLIB00000845911]

NCGC00380083-01!(E)-3-[2,4-dihydroxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one [IIN-based on: CCMSLIB00000845911]

C21H22O4 (338.1518012)


   

Licochalcone a

2-Propen-1-one, 3-(5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (E)-

C21H22O4 (338.1518012)


C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor

   

4-Hydroxyisoderricin

4-Hydroxy-7-methoxy-8-prenylflavanone

C21H22O4 (338.1518012)


   

Iselin

4-[(2,4,4-Trimethyl-1-cyclohexen-1-yl)methoxy]-7H-furo[3,2-g][1]benzopyran-7-one, 9ci

C21H22O4 (338.1518012)


   

Licoagrocarpin

14-methoxy-6-(3-methylbut-2-en-1-yl)-8,17-dioxatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,11(16),12,14-hexaen-5-ol

C21H22O4 (338.1518012)


   

2'-O-Methylglabridin

4-{8,8-dimethyl-2H,3H,4H,8H-pyrano[2,3-f]chromen-3-yl}-3-methoxyphenol

C21H22O4 (338.1518012)


   

Xanthotoxol geranyl ether

9-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-2H-furo[3,2-g]chromen-2-one

C21H22O4 (338.1518012)


D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM[1]. 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM[1].

   

2-Hydroxy-4-methoxy-3-prenyl-6-styrylbenzoic acid

2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-[(E)-2-phenylethenyl]benzoic acid

C21H22O4 (338.1518012)


D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates

   

Gancaonin X

2'-Hydroxy-4'-methoxy-6'',6''-dimethylpyrano[2'',3'':7,6]isoflavan

C21H22O4 (338.1518012)


   

2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

C21H22O4 (338.1518012)


   

Bergaptin

7H-Furo(3,2-g)(1)benzopyran-7-one, 4-((3,7-dimethyl-2,6-octadienyl)oxy)-, (E)-

C21H22O4 (338.1518012)


D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM. Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.

   

6-Hydroxy-3-[2-(6-hydroxy-2-methylchromen-2-yl)ethyl]-2,4-dimethylbenzaldehyde

6-Hydroxy-3-[2-(6-hydroxy-2-methylchromen-2-yl)ethyl]-2,4-dimethylbenzaldehyde

C21H22O4 (338.1518012)


   

(E)-3-[2,4-dihydroxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one

(E)-3-[2,4-dihydroxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-methoxyphenyl)prop-2-en-1-one

C21H22O4 (338.1518012)


   

(R)-2-(8,8-dimethyl-2,3,4,8-tetrahydropyrano[2,3-f]chromen-3-yl)-5-methoxyphenol

(R)-2-(8,8-dimethyl-2,3,4,8-tetrahydropyrano[2,3-f]chromen-3-yl)-5-methoxyphenol

C21H22O4 (338.1518012)


   

2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-6-(2-phenylethenyl)benzoic acid

2-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-6-(2-phenylethenyl)benzoic acid

C21H22O4 (338.1518012)


D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates

   

3-Hydroxy-5-methoxy-6-prenylstilbene-2-carboxylic acid

3-Hydroxy-5-methoxy-6-prenylstilbene-2-carboxylic acid

C21H22O4 (338.1518012)


   

2-O-Methylglabridin

2-O-Methylglabridin

C21H22O4 (338.1518012)


   

6-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-2-(2-phenylethenyl)benzoic acid

6-Hydroxy-4-methoxy-3-(3-methyl-2-butenyl)-2-(2-phenylethenyl)benzoic acid

C21H22O4 (338.1518012)


   

3-O-Methylcalopocarpin

3-O-Methylcalopocarpin

C21H22O4 (338.1518012)


A member of the class of pterocarpans that is (6aR,11aR)-pterocarpan substituted by a hydroxy group at position 9, a methoxy group at position 3 and a prenyl group at position 2. Isolated from Erythrina glauca and Erythrina burttii, it exhibits anti-HIV activity.

   

Hydroxymethoxyprenylstilbenecarboxylic acid

Hydroxymethoxyprenylstilbenecarboxylic acid

C21H22O4 (338.1518012)


   

4'-0-Methylbavachalcone

4'-0-Methylbavachalcone

C21H22O4 (338.1518012)


4'-O-Methylbavachalcone is a natural chalcone derivative found in various plants, including the genus Glycyrrhiza, which is commonly known for its sweet-tasting roots. This compound is characterized by its distinctive yellow color and has been the subject of interest in the field of pharmacology due to its potential biological activities. Chemically, 4'-O-Methylbavachalcone is classified as a flavonoid, a large family of compounds known for their diverse biological effects. Its structure consists of two aromatic rings (A and B rings) connected by a three-carbon chain, which includes a conjugated double bond. The presence of the methoxy group (-OCH3) at the 4' position on the B ring differentiates it from other chalcones and contributes to its unique properties. In terms of biological activity, 4'-O-Methylbavachalcone has been reported to possess several pharmacological effects, including anti-inflammatory, antioxidant, and anticancer properties. Its anti-inflammatory effects are attributed to its ability to inhibit the production of inflammatory mediators and modulate signaling pathways involved in inflammation. As an antioxidant, it helps to scavenge free radicals and reduce oxidative stress, which is associated with various diseases, including cancer. Moreover, 4'-O-Methylbavachalcone has shown promise as a potential anticancer agent. It has been found to induce apoptosis (programmed cell death) in cancer cells and inhibit the growth of tumor cells in vitro and in vivo. The exact mechanisms underlying its anticancer effects are still under investigation, but they may involve the modulation of multiple signaling pathways involved in cell proliferation, apoptosis, and angiogenesis. Overall, 4'-O-Methylbavachalcone is an interesting compound with a diverse range of biological activities, making it a potential candidate for further research and development in the field of pharmacology.

   

1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one

1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one

C21H22O4 (338.1518012)


   

5-methoxy-7-[(3-methylbut-2-en-1-yl)oxy]-2-phenyl-2,3-dihydro-1-benzopyran-4-one

5-methoxy-7-[(3-methylbut-2-en-1-yl)oxy]-2-phenyl-2,3-dihydro-1-benzopyran-4-one

C21H22O4 (338.1518012)


   

4-methoxy-5-methyl-13-(3-methylbut-2-en-1-yl)-2-oxatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3(8),4,6,9,11,13-heptaene-6,12-diol

4-methoxy-5-methyl-13-(3-methylbut-2-en-1-yl)-2-oxatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3(8),4,6,9,11,13-heptaene-6,12-diol

C21H22O4 (338.1518012)


   

(2s)-5,7-dihydroxy-2-methyl-6-(3-methylbut-2-en-1-yl)-2-phenyl-3h-1-benzopyran-4-one

(2s)-5,7-dihydroxy-2-methyl-6-(3-methylbut-2-en-1-yl)-2-phenyl-3h-1-benzopyran-4-one

C21H22O4 (338.1518012)


   

1,8-dihydroxy-3-methoxy-6-methyl-2-[(1e)-3-methylbut-1-en-1-yl]-10h-anthracen-9-one

1,8-dihydroxy-3-methoxy-6-methyl-2-[(1e)-3-methylbut-1-en-1-yl]-10h-anthracen-9-one

C21H22O4 (338.1518012)


   

6-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-2-[(1e)-2-phenylethenyl]benzoic acid

6-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-2-[(1e)-2-phenylethenyl]benzoic acid

C21H22O4 (338.1518012)


   

(1s,7r,9r,10r)-7-(furan-3-yl)-9-methyl-3-methylidene-6,16-dioxatetracyclo[8.7.0.0¹,¹⁴.0⁴,⁹]heptadeca-4,13-dien-15-one

(1s,7r,9r,10r)-7-(furan-3-yl)-9-methyl-3-methylidene-6,16-dioxatetracyclo[8.7.0.0¹,¹⁴.0⁴,⁹]heptadeca-4,13-dien-15-one

C21H22O4 (338.1518012)


   

3-(4-hydroxy-2-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-2h-chromen-7-ol

3-(4-hydroxy-2-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-2h-chromen-7-ol

C21H22O4 (338.1518012)


   

5,7-dihydroxy-8-methyl-6-(3-methylbut-2-en-1-yl)-2-phenyl-2,3-dihydro-1-benzopyran-4-one

5,7-dihydroxy-8-methyl-6-(3-methylbut-2-en-1-yl)-2-phenyl-2,3-dihydro-1-benzopyran-4-one

C21H22O4 (338.1518012)


   

{9-methoxy-3,5-dimethylnaphtho[2,3-b]furan-4-yl}methyl (2z)-2-methylbut-2-enoate

{9-methoxy-3,5-dimethylnaphtho[2,3-b]furan-4-yl}methyl (2z)-2-methylbut-2-enoate

C21H22O4 (338.1518012)


   

11-methoxy-2,2,12-trimethyl-5h,6h-naphtho[2,1-f]chromene-8,9-diol

11-methoxy-2,2,12-trimethyl-5h,6h-naphtho[2,1-f]chromene-8,9-diol

C21H22O4 (338.1518012)