Licochalcone E (BioDeep_00000229995)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(E)-3-[4-hydroxy-2-methoxy-5-[(2S)-3-methylbut-3-en-2-yl]phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

化学式: C21H22O4 (338.1518012)
中文名称: 甘草查尔酮 E, 甘草查尔酮E
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=C(C)C(C)c1cc(C=CC(=O)c2ccc(O)cc2)c(OC)cc1O
InChI: InChI=1S/C21H22O4/c1-13(2)14(3)18-11-16(21(25-4)12-20(18)24)7-10-19(23)15-5-8-17(22)9-6-15/h5-12,14,22,24H,1H2,2-4H3/b10-7+/t14-/m0/s1

描述信息

Licochalcone E is a natural product found in Glycyrrhiza inflata with data available.

同义名列表

3 个代谢物同义名

(E)-3-[4-hydroxy-2-methoxy-5-[(2S)-3-methylbut-3-en-2-yl]phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one; (S,E)-3-(4-Hydroxy-2-methoxy-5-(3-methylbut-3-en-2-yl)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one; Licochalcone E



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yongkai Cao, Yuanquan Si, Meifen Li, Dahua Fan, Meiqun Cao, Seung Hoon Cheon, Jian Liang, Pei Lu. Licochalcone E improves insulin sensitivity in palmitic acid-treated HepG2 cells through inhibition of the NLRP3 signaling pathway. International immunopharmacology. 2021 Oct; 99(?):107923. doi: 10.1016/j.intimp.2021.107923. [PMID: 34229177]
  • Fei Zeng, Wenxing Wu, Yiying Zhang, Xin Pan, Jinao Duan. Rapid screening of lipase inhibitors in licorice extract by using porcine pancreatic lipase immobilized on Fe3O4 magnetic nanoparticles. Food & function. 2021 Jun; 12(12):5650-5657. doi: 10.1039/d0fo03352a. [PMID: 34018495]
  • Yan Lin, Yi Kuang, Kai Li, Shuang Wang, Shuai Ji, Kuan Chen, Wei Song, Xue Qiao, Min Ye. Nrf2 activators from Glycyrrhiza inflata and their hepatoprotective activities against CCl4-induced liver injury in mice. Bioorganic & medicinal chemistry. 2017 10; 25(20):5522-5530. doi: 10.1016/j.bmc.2017.08.018. [PMID: 28835349]
  • Yan Lin, Yi Kuang, Kai Li, Shuang Wang, Wei Song, Xue Qiao, Gulnar Sabir, Min Ye. Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. Bioorganic & medicinal chemistry. 2017 07; 25(14):3706-3713. doi: 10.1016/j.bmc.2017.05.009. [PMID: 28522265]
  • Soo Jin Kwon, So Young Park, Gyoo Taik Kwon, Ki Won Lee, Young-Hee Kang, Myung-Sook Choi, Jong Won Yun, Jae-Ho Jeon, Jong Gab Jun, Jung Han Yoon Park. Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model. Cancer prevention research (Philadelphia, Pa.). 2013 Jun; 6(6):603-13. doi: 10.1158/1940-6207.capr-13-0012. [PMID: 23625311]
  • Hong Gyu Park, Eun Jung Bak, Gye-Hyeong Woo, Jin Moon Kim, Zhejiu Quan, Jung Mogg Kim, Ho-Kun Yoon, Seung Hoon Cheon, Goo Yoon, Yun-Jung Yoo, Younghwa Na, Jeong-Heon Cha. Licochalcone E has an antidiabetic effect. The Journal of nutritional biochemistry. 2012 Jul; 23(7):759-67. doi: 10.1016/j.jnutbio.2011.03.021. [PMID: 21840191]
  • Tiezhong Zhou, Xuming Deng, Jiazhang Qiu. Antimicrobial activity of licochalcone E against Staphylococcus aureus and its impact on the production of staphylococcal alpha-toxin. Journal of microbiology and biotechnology. 2012 Jun; 22(6):800-5. doi: 10.4014/jmb.1112.12020. [PMID: 22573157]