Exact Mass: 324.0181
Exact Mass Matches: 324.0181
Found 32 metabolites which its exact mass value is equals to given mass value 324.0181,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
5-O-(1-Carboxyvinyl)-3-phosphoshikimate
Dorzolamide
Dorzolamide is only found in individuals that have used or taken this drug. It is a carbonic anhydrase (CA) inhibitor. It is used in ophthalmic solutions (Trusopt) to lower intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension.Dorzolamide is a sulfonamide and a highly specific carbonic anhydrase II (CA-II) inhibitor, which is the main CA isoenzyme involved in aqueous humor secretion. Inhibition of CA-II in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. Dorzolamide also accumulates in red blood cells as a result of CA-II binding, as CA-II is found predominantly in erythrocytes. However, sufficient CA-II activity remains so that adverse effects due to systemic CA inhibition are not observed. S - Sensory organs > S01 - Ophthalmologicals > S01E - Antiglaucoma preparations and miotics > S01EC - Carbonic anhydrase inhibitors D004791 - Enzyme Inhibitors > D002257 - Carbonic Anhydrase Inhibitors D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents C471 - Enzyme Inhibitor > C29577 - Carbonic Anhydrase Inhibitor
1-(3',4'-Dichloro-2-fluoro(1,1'-biphenyl)-4-yl)cyclopropanecarboxylic acid
D004791 - Enzyme Inhibitors > D000091062 - Gamma Secretase Inhibitors and Modulators C471 - Enzyme Inhibitor
2'-Deoxy-5'-O-thiophosphonouridine
1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea
(3R)-6-hydroxy-3-hydroxymethyl-2-methyl-2,3-dihydro-10H-3r,10ac-epidisulfano-pyrazino[1,2-a]indole-1,4-dione|Dehydrogliotoxin|Dehydroglyotoxin
PRZ_M325
CONFIDENCE Transformation product, tentative ID (Level 2b); INTERNAL_ID 2007
diethoxy-(4-methylsulfonylphenoxy)-sulfanylidene-λ5-phosphane
1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-fluoro-1-[(4-methylphenyl)sulfonyl]-
1H-Pyrrolo[2,3-b]pyridine, 4-chloro-3-fluoro-1-[(4-methylphenyl)sulfonyl]-
trans-6-Methyl-4-ethylamino-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide
5-(4-fluorophenyl)-1-methyl-1H-pyrazol-3-yltrifluoromethanesulfonate
2-(4-CHLOROSULPHONYLPHENYL)ETHYLTRIMETHOXYSILANE50 IN METHYLENE CHLORIDE
2-(TRIFLUOROMETHYL)-5-[4-(TRIFLUOROMETHYL)PHENYL]-3-FUROIC ACID
N-[5-(2,3-dihydro-1,4-dioxin-5-yl)-1,3,4-oxadiazol-2-yl]-5-nitro-2-thiophenecarboxamide
1-[5-(Dihydroxyphosphinothioyloxymethyl)-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione
N-(5-bromo-2-hydroxyphenyl)-5-propyl-3-isoxazolecarboxamide
1-(3,4-Dichlorophenyl)-3-(3,5-dimethylphenyl)thiourea
Dorzolamide
S - Sensory organs > S01 - Ophthalmologicals > S01E - Antiglaucoma preparations and miotics > S01EC - Carbonic anhydrase inhibitors D004791 - Enzyme Inhibitors > D002257 - Carbonic Anhydrase Inhibitors D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents C471 - Enzyme Inhibitor > C29577 - Carbonic Anhydrase Inhibitor
