Exact Mass: 307.10495380000003

Tolnaftate

N-Methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide

Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athletes foot and ringworm. It is sold under several brand names, most notably Tinactin (Schering-Plough Corporation) and Odor-Eaters (Combe Incorporated). Other brands are Absorbine, Aftate, Desenex, Genaspor, NP 27, and Ting.and Odor-Eaters (Combe Incorporated). Other brands are Absorbine, Aftate, Desenex, Genaspor, NP 27, and Ting. [HMDB] Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athletes foot and ringworm. It is sold under several brand names, most notably Tinactin (Schering-Plough Corporation) and Odor-Eaters (Combe Incorporated). Other brands are Absorbine, Aftate, Desenex, Genaspor, NP 27, and Ting.and Odor-Eaters (Combe Incorporated). Other brands are Absorbine, Aftate, Desenex, Genaspor, NP 27, and Ting. D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use D000890 - Anti-Infective Agents > D000935 - Antifungal Agents C254 - Anti-Infective Agent > C514 - Antifungal Agent

Aspergillomarasmine A

2-({2-[(2-amino-2-carboxyethyl)amino]-2-carboxyethyl}amino)butanedioic acid

Aspergillomarasmine A is a metabolite of the cereal fungus (Aspergillus flavus), found only in young culture D018377 - Neurotransmitter Agents > D018846 - Excitatory Amino Acids

Tryptophyl-Cysteine

2-{[2-amino-1-hydroxy-3-(1H-indol-3-yl)propylidene]amino}-3-sulphanylpropanoic acid

Tryptophyl-Cysteine is a dipeptide composed of tryptophan and cysteine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an Expected metabolite.

Cysteinyl-Tryptophan

2-[(2-Amino-1-hydroxy-3-sulphanylpropylidene)amino]-3-(1H-indol-3-yl)propanoic acid

Cysteinyl-Tryptophan is a dipeptide composed of cysteine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an Expected metabolite.

Hydroxyfasudil

5-(1,4-Diazepane-1-sulphonyl)isoquinolin-1-ol

N-[1-(2-Oxochromen-3-yl)ethylideneamino]pyridine-4-carboxamide

N-[1-(2-oxo-2H-chromen-3-yl)ethylidene]pyridine-4-carbohydrazide

Toluidine

(1Z)-1-[2-(4-methyl-2-nitrophenyl)hydrazin-1-ylidene]-1,2-dihydronaphthalen-2-one

Toluidine, also known as toluidine red or c.i. pigment red 3, is a member of the class of compounds known as naphthalenes. Naphthalenes are compounds containing a naphthalene moiety, which consists of two fused benzene rings. Toluidine is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Toluidine can be found in wild celery, which makes toluidine a potential biomarker for the consumption of this food product. The chemical properties of the toluidines are quite similar to those of aniline, and toluidines have properties in common with other aromatic amines. Due to the amino group bonded to the aromatic ring, the toluidines are weakly basic. The toluidines are poorly soluble in pure water but dissolve well in acidic water due to formation of ammonium salts, as usual for organic amines. ortho- and meta-toluidines are viscous Liquids, but para-toluidine is a flaky solid. This difference is related to the fact that the p-toluidine molecules are more symmetrical. p-Toluidine can be obtained from reduction of p-nitrotoluene. p-Toluidine reacts with formaldehyde to form Tr√∂gers base . Toluidine, also known as toluidine red or c.i. pigment red 3, is a member of the class of compounds known as naphthalenes. Naphthalenes are compounds containing a naphthalene moiety, which consists of two fused benzene rings. Toluidine is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Toluidine can be found in wild celery, which makes toluidine a potential biomarker for the consumption of this food product. The chemical properties of the toluidines are quite similar to those of aniline, and toluidines have properties in common with other aromatic amines. Due to the amino group bonded to the aromatic ring, the toluidines are weakly basic. The toluidines are poorly soluble in pure water but dissolve well in acidic water due to formation of ammonium salts, as usual for organic amines. ortho- and meta-toluidines are viscous liquids, but para-toluidine is a flaky solid. This difference is related to the fact that the p-toluidine molecules are more symmetrical. p-Toluidine can be obtained from reduction of p-nitrotoluene. p-Toluidine reacts with formaldehyde to form Trögers base .

tolnaftate

C16H17NO3.HCl (307.09751480000006)

Demethyl

1-[(4-Hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol--hydrogen chloride (1/1)

Higenamine hydrochloride (Norcoclaurine hydrochloride), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine hydrochloride (Norcoclaurine hydrochloride) has anti-apoptotic effects[1][2]. Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases[1][2][3][4][5][6]. Higenamine hydrochloride (Norcoclaurine hydrochloride), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine hydrochloride (Norcoclaurine hydrochloride) has anti-apoptotic effects[1][2].

CONFIDENCE Transformation product, tentative ID (Level 3 structure); INTERNAL_ID 2101

CP_M308b

C15H18ClN3O2 (307.1087478)

CONFIDENCE Transformation product, tentative ID (Level 3 structure); INTERNAL_ID 2102

CP_M308c

C15H18ClN3O2 (307.1087478)

CONFIDENCE Transformation product, tentative ID (Level 3 structure); INTERNAL_ID 2103

MLS000029711

MMV676384

C18H14FN3O (307.1120846)

2-indolylcarbonyl alpha-L-rhamnopyranoside|3-indolylcarbonyl alpha-L-rhamnopyranoside

Asp Ser Ser

Ser Asp Ser

Demethyl

1-[(4-Hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol--hydrogen chloride (1/1)

tolnaftate

D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use D000890 - Anti-Infective Agents > D000935 - Antifungal Agents C254 - Anti-Infective Agent > C514 - Antifungal Agent CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10164; ORIGINAL_PRECURSOR_SCAN_NO 10163 CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10182; ORIGINAL_PRECURSOR_SCAN_NO 10181 CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10208; ORIGINAL_PRECURSOR_SCAN_NO 10207 CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10225; ORIGINAL_PRECURSOR_SCAN_NO 10224 CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10249; ORIGINAL_PRECURSOR_SCAN_NO 10244

MMV676395

MMV676384

C18H14N3OF (307.1120846)

Ser Ser Asp

C14H17N3O3S1 (307.09905720000006)

Cys Trp

Trp Cys

C14H17N3O3S1 (307.09905720000006)

Cys-TRP

2-[2-amino-3-(1H-indol-3-yl)propanamido]-3-sulfanylpropanoic acid

TRP-Cys

2-(2-amino-3-sulfanylpropanamido)-3-(1H-indol-3-yl)propanoic acid

Toxin C

2-({2-[(2-amino-2-carboxyethyl)amino]-2-carboxyethyl}amino)butanedioic acid

D018377 - Neurotransmitter Agents > D018846 - Excitatory Amino Acids

(2S)-4-oxo-2-(phenylmethoxycarbonylamino)-4-prop-2-enoxybutanoate

8-hydroxyquinoline-beta-d-galactopyranoside

4-chloro-7-methoxy-5-(1-methylpiperidin-4-yl)oxyquinazoline

C15H18ClN3O2 (307.1087478)

pth-l-proline

Ethanone, 1-(3,5-dihydroxyphenyl)-2-[methyl(phenylmethyl)amino]-, hydrochloride

C9H17N5O5S (307.09503520000004)

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine

C16H13N5O2 (307.1069198)

2-amino-4-methylsulfanylbutanoic acid,(2,5-dioxoimidazolidin-4-yl)urea

[1-[(2-methylpropan-2-yl)oxycarbonyl]-5-methylsulfanylindol-2-yl]boronic acid

C14H18BNO4S (307.10495380000003)

(4-CYCLOHEXYL-5-FURAN-2-YL-4H-[1,2,4]TRIAZOL-3-YLSULFANYL)-ACETIC ACID

(2E,4E)-4-(1-ETHYLQUINOLIN-2(1H)-YLIDENE)-1-PHENYLBUT-2-EN-1-ONE

C12H27OSn (307.10837819999995)

Tributyltin oxide

4-[3-[4-(Methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl]piperidine

C17H14BNO4 (307.10158340000004)

2-(4-boronophenyl)-6-methylquinoline-4-carboxylic acid

4-(5-Isoquinolinylsulfonyl)-1,4-diazepan-1-ol

Fasudil Pyridine N-Oxide TFA Salt

Cyclopentylalbendazole sulfoxide

3-(2-Chloro-1-oxopropyl)spiro[2H-1,3-benzoxazine-2,1-cyclohexan]-4(3H)-one

14H-Benzo[c]benzofuro[2,3-a]carbazole

C22H13NO (307.09970880000003)

Sulfasymazine

C13H17N5O2S (307.1102902)

C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides

8-HYDROXYQUINOLINE-BETA-D-GLUCOPYRANOSIDE

A-68930 hydrochloride

A68930 hydrochloride, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis[1].

ETHYL 4-HYDROXY-5,6,8-TRIMETHOXYQUINOLINE-2-CARBOXYLATE