tolnaftate (BioDeep_00000399030)

   

natural product


代谢物信息卡片


O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate

  化学式: C19H17NOS (307.1031)
中文名称: 托萘酯
  谱图信息: 最多检出来源 () %

分子结构信息

SMILES: C1(N(C(OC2=CC=C3C(=C2)C=CC=C3)=S)C)=CC(=CC=C1)C
InChI: InChI=1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3


描述信息

D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
C254 - Anti-Infective Agent > C514 - Antifungal Agent
CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10164; ORIGINAL_PRECURSOR_SCAN_NO 10163
CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10182; ORIGINAL_PRECURSOR_SCAN_NO 10181
CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10208; ORIGINAL_PRECURSOR_SCAN_NO 10207
CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10225; ORIGINAL_PRECURSOR_SCAN_NO 10224
CONFIDENCE standard compound; INTERNAL_ID 850; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10249; ORIGINAL_PRECURSOR_SCAN_NO 10244

同义名列表

348 个代谢物同义名

tolnaftate; 0-2-NAPHTHYL M,N-DIMETHYLTHIOCARBANILATE; 06KB629TKV; 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate; Absorbine; Aftate; Aftate Athlete Foot Cream; Aftate for athlete's foot gel; Aftate for jock itch aerosol spray powder; Aftate for jock itch gel; Aftate for jock itch sprinkle powder; Antifungal Athlete Foot Cream to Powder Tolnaftate; Antifungal Continuous Liquid Spray; Antifungal Cream Tolnaftate 1%; Antifungal Liquid Maximum Strength; Antifungal Liquid Spray; Antifungal Powder Spray; Antifungal Powder Spray with Baking Soda; Antifungal Spray Liquid; Antifungal TolnaftateLiquid Continuous Spray; antifungalfoot care; ANTIFUNGALFor Athletes Foot; Athlete Foot 2 Way Spray; Athlete Foot Powder; Athletes Foot Antifungal Liquid Spray; Athletes FootAntifungal; Atopalm Tolnaftate Antifungal; AVON HeXashield Athletes Foot; AVON HeXashield Athletes FootCream; Barielle Fungus Rx Maximum Strength Anti-fungal; Barielle Professional Maximum Strength Fungus Rx Antifungal Pro; Bengama Antifungal; Bengama-Tolnaftate; Bio-scriptives Extreme AF; BlistexOdor-Eaters Powder; BPBio1_000285; Breezee; CANESPIES; Carbamothioic acid, methyl(3-methylphenyl)-, O-2-naphthalenyl ester; CARBAMOTHIOIC ACID, METHYL(3-METHYLPHENYL)-,0-2-NAPHTHALENYL ESTER; Carbamothioic acid, N-methyl-N-(3-methylphenyl)-, O-2-naphthalenyl ester; Carbamothioic acid, O-2-naphthalenyl ester; CARBANILIC ACID, M,N-DEMETHYLTHIO-, 0-2-NAPHTHYL ESTER; Carbanilic acid, m,N-dimethylthio-, O-2-naphthyl ester; Carbanilic acid, N,m-dimethylthio-, O-2-naphthyl ester; Carbanilic acid,m-dimethylthio-, O-2-naphthyl ester; Carbanilic acid,N-dimethylthio-, O-2-naphthyl ester; Careall Tolnaftate; Chinofungin; Chlorisept; Cidacin Antifungal Treatment; CLARUS AC Antifungal Solution; Clarus Antifungal; Conazolantifungal; Curatin; CVS Health Antifungal Anthletes Foot; CVS Health Athletes Foot; D01AE18; Defense Antifungal Medicated Bar; Derman antifungal cream; Derman Antifungal Powder Tolnaftate; DERMATOOL Fungal Nail Solution; Dermatool Fungal Nail Treatment; Dermoxin; Dg Athletes Foot; Dg Health Athletes Foot; DivK1c_000334; Dr Canuso Fungal Nail Eraser; Dr. Canuso Foot Repair Serum; Dr. Gs Clear Nail; Dr. Luke Fungal Nail Renewal; Dr. Scholl's athlete's foot spray; Dr. Scholls Instant Cool Athletes foot treatment with Menthol; Dr. Scholls Instant Cool Athletes Foot Wipes; Dungistop; Equate Athletes Foot; Equate Liquid Foot; Family Care Tolnaftate; Family Wellness Tolnaftate; First Aid Antifungal Medicated; First Aid Antifungal Medicated Cream 0.5 Oz; First Aid Antifungal Medicated Cream 1oz; FLAWLESS NAILS; Flexitol Medicated Foot; Focusan; Foot and Sneaker Spray; Foot Odor Control Powder; Foot Odor Control Powder Spray; Foot Odor Control Spray; Foot Odor Control Spray Powder; Foot Works HealthyAntifungal; Formula 3; Formula 7 THEGEL; Formula 7-The Solution; Forticept Antifungal Balm; Fungablend 10; Fungal Nail Renewal; Fungi Nail Anti-Fungal Pen; Fungi Nail Toe and Foot; Fungicure Anti-Fungal Liquid; Fungifoam; FUNGINIX AF; FUNGINIX JOCK ITCH TREATMENT; FUNGISOLVE TOLNAFTATE ANTIFUNGAL; Fungistop; Fungus Relief; Gadaderm Antifungal; Genaspor; Genaspore cream; Gold Mountain Beauty Fungal Nail Eliminator; Gold Mountain Beauty Intensive Repair Serum; Good Neighbor Pharmacy Maximum Strength Athletes Foot Relief Antifungal; GoodSense Athletes Foot Antifungal; GoodSense Powder Jock Itch Antifungal; HC Max Anti Fungal; HC Max Anti-Fungal; HC Max For Athletes Foot; HC MAX FOR JOCK ITCH; HC Max Hongo Cura; Hi Vetic; Hi-alarzin; HI-Alazin; Homehealth Antifungal; HONGOSAN DSP; IDI1_000334; Jock Itch Powder; KBio1_000334; KBio2_001443; KBio2_004011; KBio2_006579; KERACTILPlus; Kerasal Athletes Foot powder; Kerasal for Athletes Foot Silky Clear; Kiss Fungi-GoneAnti-fungal Treatment; Leader Antifungal Tolnaftate; Lotrimin Daily Prevention; Lotrimin Daily Prevention Deo; LUCKY SUPER SOFT ANTIFUNGAL; LUCKY SUPER SOFT ANTIFUNGALFor Athletes Foot; m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester; Maximum Strength Anti Fungal Tolnaftate 1%; Maximum Strength Antifungal Liquid; Meijer Antifungal Tolnaftate Cream; Meijer Athletes Foot Liquid; Meijer Athletes Foot Liquid Spray; Meijer Maximum Strength Anthletes foot Antifungal; Meijer Maximum Strength Athletes Foot Antifungal; Meijer Maximum Strength Jock Itch Relief Antifungal; meijerantifungal; Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester; Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester; Methyl(3-methylphenyl)carbamothioic Acid O-2-Naphthyl Ester; Micoisdin; Micomitin Antifungal; Micotrin AL; MIRACURE; Molecular AF; Mycozyl AL; N-Methyl-(3-methylphenyl)-carbamothioic acid, O-2-naphthalenyl ester; N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide; N-methyl-N-(3-methylphenyl)-1-naphthalen-2-yloxy-methanethioamide; N-methyl-N-(3-methylphenyl)carbamothioic acid O-(2-naphthalenyl) ester; N-Methyl-N-(3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester;Methyl(3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester ;2-Naphthyl N-methyl-N-(3-tolyl)thiocarbamate; N-methyl-N-(m-tolyl)thiocarbamic acid O-(2-naphthyl) ester; Nail Renew; Nail Renu; Nailene Antifungal Treatment; Naphthiomate T; Naphthiomate-T; NATUREPLEX TOLNAFTATE; NATUREPLEX TOLNAFTATEANTIFUNGAL; Novonail Solution; NP 27; NP-27; NP-27 Cream; NP-27 Powder; NP-27 Spray Powder; NP27; O-(2-Naphthyl) methyl(3-methylphenyl)thiocarbamate #; O-(2-naphthyl) N-methyl-N-(m-tolyl)carbamothioate; O-(naphthalen-2-yl) methyl(m-tolyl)carbamothioate; O-2-Naphthyl m,N-dimethylthiocarbanilate; O-2-naphthyl methyl(3-methylphenyl)carbamothioate; O-2-Naphthyl methyl(3-methylphenyl)thiocarbamate; O-2-Naphthyl N,N-dimethylthiocarbanilate; O-naphthalen-2-yl methyl(3-methylphenyl)carbamothioate; O-naphthalen-2-yl methyl(m-tolyl)carbamothioate; O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate; O-Naphthalen-2-yl N-methyl-N-(3-methylphenyl)thiocarbamate; O-naphthalen-2-ylmethyl(m-tolyl)carbamothioate; Odor Control Powder Spray; Ongo-Fin; Ony Clear; Ony-Clear; Opti-Nail 2-in-1; Personal Care Antifungal; Phytoderm; PHYTOZINE RINGWORM TREATMENT; PHYTOZINE RINGWORM TREATMENTMAXIMUM STRENGTH; Pitrex; Pitrex cream; Premier Solutions Antifungal Tolnaftate Liquid; Premier Solutions Antifungal Tolnaftate Powder; Premier Value Tolnaftate Antifungal; Prestwick0_000070; Prestwick1_000070; Prestwick2_000070; Prestwick3_000070; ProClearz; Proclearz Maximum Strength Fungal Shield Brush-ON Antifungal; ProClearzMaximum Strength Fungal Shield Brush-on Antifungal; Purder N, Tolnaftat; Quality Choice Antifungal; Quality Choice Tolnaftate Antifungal; Relispray Antifungal Liquid; Rite Aid Athletes Foot; Rugby Tolnaftate 1% Powder; Sanafitil Crema; Separin; Separin (TN); Signature Athletes Foot Antifungal; Signature Black Bottle Tea Tree Antifungal Foot and Body Wash; Signature Care Antifungal Cream Tolnaftate 1%; Signature Care Athletes Foot Antifungal; Silka Antifungal; SKINHEAL ANTIFUNGAL; Smart Sense Tolnaftate Antifungal; Smart Sense Tolnftate Antifungal; SmartSense Maximum Strength Athletes Foot Relief antifungal; Smooth AF; Sorgoa; Spectrum2_000950; Spectrum4_000360; Spectrum5_001000; Sporiline; sunmarkantifungal; Targetantifungal; Terpenicol Antifungal Solution; Thera plus Antifungal Tolnaftate; TheraCare Antifungal Cream; Timoped; Tinactin; Tinactin (TN); Tinactin aerosol liquid; Tinactin aerosol powder; Tinactin antifungal deodorant powder aerosol; Tinactin cream; Tinactin jock itch aerosol powder; Tinactin jock itch cream; Tinactin jock itch spray powder; Tinactin plus aerosol powder; Tinactin plus powder; Tinactin pound>>Tinaderm pound>>Aftate pound>>NP-27 pound>>NP 27 pound>> NP27; Tinactin powder; TinactinAntifungal; Tinaderm; Tinatox; Tinavet; Tinavet (Veterinary); Tinavet Cream 1%; Tineacide; Tineafax; Ting; Ting antifungal cream; Ting antifungal powder; Ting antifungal spray liquid; Ting antifungal spray powder; TM-Tolnaftate; TM-Tolnaftate LR; Tniaderm; Toe Area Treatment; Tolcylen Antifungal Solution; Tolmaftate; Tolnafate; Tolnafi-AL; Tolnaftat Purder N; TOLNAFTATE (EP MONOGRAPH); Tolnaftate (JP17/USP/INN); TOLNAFTATE (MART.); Tolnaftate (Standard); Tolnaftate (USAN:USP:INN:BAN:JAN); TOLNAFTATE (USP MONOGRAPH); TOLNAFTATE (USP-RS); TOLNAFTATE [EP MONOGRAPH]; TOLNAFTATE [GREEN BOOK]; TOLNAFTATE [INN]; TOLNAFTATE [JAN]; TOLNAFTATE [MART.]; TOLNAFTATE [MI]; Tolnaftate [USAN:USP:INN:BAN:JAN]; TOLNAFTATE [USAN]; TOLNAFTATE [USP MONOGRAPH]; TOLNAFTATE [USP-RS]; TOLNAFTATE [VANDF]; TOLNAFTATE [WHO-DD]; Tolnaftate 1%; Tolnaftate Antifungal; Tolnaftate Athletes Foot Powder Spray; Tolnaftate Athletes Foot Powder Spray Talc Free; Tolnaftate Cream 1%; Tolnaftate Cream 1% ANTIFUNGAL; Tolnaftate for system suitability; Tolnaftate for system suitability, European Pharmacopoeia (EP) Reference Standard; Tolnaftate Jock Itch Powder Spray Talc Free; Tolnaftate Jock Itch Powder Spray-Talc Free; Tolnaftate Oil; Tolnaftate Powder Spray; Tolnaftate Powder Spray Talc Free; Tolnaftate Powder Spray-Talc Free; Tolnaftate serum; Tolnaftate Spray; Tolnaftate, European Pharmacopoeia (EP) Reference Standard; Tolnaftate, Pharmaceutical Secondary Standard; Certified Reference Material; Tolnaftate, United States Pharmacopeia (USP) Reference Standard; Tolnaftate; O-Naphthalen-2-yl methyl(3-methylphenyl)carbamothioate; TolnaftateAntifungal; TolnaftateD; Tolnaftato; Tolnaftato (INN-Spanish); Tolnaftato [DCIT]; Tolnaftato [INN-Spanish]; Tolnaftatum; Tolnaftatum (INN-Latin); Tolnaftatum [INN-Latin]; Tolnaphthate; tolnoftate; Tolsanil; Tonoftal; TopCareTolnaftate Antifungal; Tox21_110521; Tox21_110521_1; Tox21_301363; Tritin; UNII-06KB629TKV; up and up antifungal; Up and Up Soothing Antifungal; Villimed Antifungal; Walgreens Athletes Foot; Walgreens Maximum Strength Jock Itch Antifungal; Walgreens Tolnaftate; Western FamilyAntifungal; Wick Storm Tea Tree Antifungal Foot Body Wash; Winco Antifungal; Winco Foods Tolnaftate; Woodwards Mycocide Clinical NS; Xtracare Antifungal Foot; ZeaSorb; Zeasorb-AF powder



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc()

PlantCyc()

代谢反应

个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Na Zhang, Jiaqi Fu, Xin Gao, Fang Lu, Yi Lu, Shumin Liu. Integrated Brain Metabolomics and Network Pharmacology Analysis to Reveal the Improvement Effect of Bai Chan Ting on Parkinson's Disease. BioMed research international. 2022; 2022(?):6113093. doi: 10.1155/2022/6113093. [PMID: 36523484]
  • Catherine Dubé. Re-FIT-ting Colorectal Cancer Screening During and Beyond COVID. Gastroenterology. 2021 08; 161(2):418-420. doi: 10.1053/j.gastro.2021.05.004. [PMID: 33974936]
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  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Anja Grabke, Dolores Fernández-Ortuño, Achour Amiri, Xingpeng Li, Natália A Peres, Powell Smith, Guido Schnabel. Characterization of iprodione resistance in Botrytis cinerea from strawberry and blackberry. Phytopathology. 2014 Apr; 104(4):396-402. doi: 10.1094/phyto-06-13-0156-r. [PMID: 24156554]
  • Pierre Leroux, Michel Gredt, Florent Remuson, Annie Micoud, Anne-Sophie Walker. Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae. Pest management science. 2013 Jan; 69(1):15-26. doi: 10.1002/ps.3408. [PMID: 23073993]
  • Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals. 2012 Dec; 40(12):2332-41. doi: 10.1124/dmd.112.047068. [PMID: 22961681]
  • Xiaohui Yang, Kingsley A Boateng, Li Yuan, Shuang Wu, Tobias I Baskin, Christopher A Makaroff. The radially swollen 4 separase mutation of Arabidopsis thaliana blocks chromosome disjunction and disrupts the radial microtubule system in meiocytes. PloS one. 2011 Apr; 6(4):e19459. doi: 10.1371/journal.pone.0019459. [PMID: 21559383]
  • Xristo Zárate, David C Henderson, Keenan C Phillips, April D Lake, David W Galbraith. Development of high-yield autofluorescent protein microarrays using hybrid cell-free expression with combined Escherichia coli S30 and wheat germ extracts. Proteome science. 2010 Jun; 8(?):32. doi: 10.1186/1477-5956-8-32. [PMID: 20546627]
  • Intzar Ali, Farrah G Khan, Krishan A Suri, Bishan D Gupta, Naresh K Satti, Prabhu Dutt, Farhat Afrin, Ghulam N Qazi, Inshad A Khan. In vitro antifungal activity of hydroxychavicol isolated from Piper betle L. Annals of clinical microbiology and antimicrobials. 2010 Feb; 9(?):7. doi: 10.1186/1476-0711-9-7. [PMID: 20128889]
  • Matthias Kretschmer, Michaela Leroch, Andreas Mosbach, Anne-Sophie Walker, Sabine Fillinger, Dennis Mernke, Henk-Jan Schoonbeek, Jean-Marc Pradier, Pierre Leroux, Maarten A De Waard, Matthias Hahn. Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea. PLoS pathogens. 2009 Dec; 5(12):e1000696. doi: 10.1371/journal.ppat.1000696. [PMID: 20019793]
  • Trang T Nguyen, Kelvin Rembert, John C Conboy. Label-free detection of drug-membrane association using ultraviolet-visible sum-frequency generation. Journal of the American Chemical Society. 2009 Feb; 131(4):1401-3. doi: 10.1021/ja8070607. [PMID: 19140762]
  • Tatsuya Sawasaki, Masahiro Nishihara, Yaeta Endo. RIP and RALyase cleave the sarcin/ricin domain, a critical domain for ribosome function, during senescence of wheat coleoptiles. Biochemical and biophysical research communications. 2008 Jun; 370(4):561-5. doi: 10.1016/j.bbrc.2008.03.124. [PMID: 18395011]
  • Albrecht Serfling, Johannes Wohlrab, Holger B Deising. Treatment of a clinically relevant plant-pathogenic fungus with an agricultural azole causes cross-resistance to medical azoles and potentiates caspofungin efficacy. Antimicrobial agents and chemotherapy. 2007 Oct; 51(10):3672-6. doi: 10.1128/aac.00654-07. [PMID: 17620378]
  • Wen-Qing Wu. [Exploration on the academic achievements of YAN Cangshan's Yi jingjia ting zi liao ji (self-treatment for pestilent convulsion)]. Zhonghua yi shi za zhi (Beijing, China : 1980). 2006 Oct; 36(4):215-8. doi: ". [PMID: 17533696]
  • Louise J Salt, James A Robertson, John A Jenkins, Francis Mulholland, E N Clare Mills. The identification of foam-forming soluble proteins from wheat (Triticum aestivum) dough. Proteomics. 2005 Apr; 5(6):1612-23. doi: 10.1002/pmic.200401035. [PMID: 15789342]
  • Samar Afify, Ulf R Rapp, Petra Högger. Validation of a liquid chromatography assay for the quantification of the Raf kinase inhibitor BAY 43-9006 in small volumes of mouse serum. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2004 Sep; 809(1):99-103. doi: 10.1016/j.jchromb.2004.06.003. [PMID: 15282098]
  • W Iwatani, T Arika, H Yamaguchi. Two mechanisms of butenafine action in Candida albicans. Antimicrobial agents and chemotherapy. 1993 Apr; 37(4):785-8. doi: 10.1128/aac.37.4.785. [PMID: 8494375]
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  • N H Georgopapadakou, B A Dix, S A Smith, J Freudenberger, P T Funke. Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans. Antimicrobial agents and chemotherapy. 1987 Jan; 31(1):46-51. doi: 10.1128/aac.31.1.46. [PMID: 3551826]