Exact Mass: 296.9749
Exact Mass Matches: 296.9749
Found 108 metabolites which its exact mass value is equals to given mass value 296.9749,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Hydrochlorothiazide
Hydrochlorothiazide is a thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It has been used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism. -- Pubchem. Hydrochlorothiazide (Apo-Hydro, Aquazide H, Microzide, Oretic), sometimes abbreviated HCT, HCTZ, or HZT is a popular diuretic drug that acts by inhibiting the kidneys ability to retain water. This reduces the volume of the blood, decreasing peripheral vascular resistance. Chlorothiazide, a carbonic anhydrase inhibitor. --Wikipedia. A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It has been used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism. -- Pubchem CONFIDENCE standard compound; INTERNAL_ID 514; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2043; ORIGINAL_PRECURSOR_SCAN_NO 2040 CONFIDENCE standard compound; INTERNAL_ID 514; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2023; ORIGINAL_PRECURSOR_SCAN_NO 2022 CONFIDENCE standard compound; INTERNAL_ID 514; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2034; ORIGINAL_PRECURSOR_SCAN_NO 2032 CONFIDENCE standard compound; INTERNAL_ID 514; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2037; ORIGINAL_PRECURSOR_SCAN_NO 2035 CONFIDENCE standard compound; INTERNAL_ID 514; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2060; ORIGINAL_PRECURSOR_SCAN_NO 2058 CONFIDENCE standard compound; INTERNAL_ID 514; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2039; ORIGINAL_PRECURSOR_SCAN_NO 2037 C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators
2-Chloroticlopidine
2-Chloroticlopidine is only found in individuals that have used or taken Ticlopidine. 2-Chloroticlopidine is a metabolite of Ticlopidine. 2-chloroticlopidine belongs to the family of Thienopyridines. These are heterocyclic compounds containing a thiophene ring fused to a pyridine ring.
Cisplatin
Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide
Rubber, natural-smoked sheet and latex solids (hevea brasiliensis)
Rubber, natural-smoked sheet and latex solids (hevea brasiliensis) is a member of the class of compounds known as phenyl phosphates. Phenyl phosphates are aromatic organooxygen compounds containing a phosphate group, which is O-esterified with a phenyl group. Rubber, natural-smoked sheet and latex solids (hevea brasiliensis) is slightly soluble (in water) and a moderately acidic compound (based on its pKa). Rubber, natural-smoked sheet and latex solids (hevea brasiliensis) can be found in a number of food items such as sapodilla, fig, chicory, and common salsify, which makes rubber, natural-smoked sheet and latex solids (hevea brasiliensis) a potential biomarker for the consumption of these food products.
hydrochlorothiazide
C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents CONFIDENCE standard compound; EAWAG_UCHEM_ID 2610 D049990 - Membrane Transport Modulators
Acetylsulfathiazole
CONFIDENCE standard compound; EAWAG_UCHEM_ID 249 CONFIDENCE standard compound; INTERNAL_ID 2010
PRZ_M298
CONFIDENCE Transformation product, tentative ID (Level 3 structure); INTERNAL_ID 2008
hydrochlorothiazide
C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators CONFIDENCE Reference Standard (Level 1)
3-amino-5-(4-bromophenyl)thiophene-2-carboxylic acid
1-(2,5-Dichlorophenyl)-3-propeneamido-5-pyrazolone
Benzamide, 4-bromo-N-(5-methyl-1,3,4-thiadiazol-2-yl
1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonamide
2-CHLORO-N-[4-(3-NITRO-PHENYL)-THIAZOL-2-YL]-ACETAMIDE
8-(TRIFLUOROMETHOXY)-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL
methyl 2-bromo-5-phenyl-1,3-thiazole-4-carboxylate
2-bromo-1-(4-methyl-2-pyrazin-2-yl-1,3-thiazol-5-yl)ethanone
6-bromo-5-methoxy-1H-indole-2-carboxylic acid ethyl ester
4-CHLORO-3-HYDROXY-5-(TRIFLUOROMETHYL)-1,1-BIPHENYL-4-CARBONITRILE
ethyl 6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate
methyl 3-(benzenesulfonamido)thiophene-2-carboxylate
1h-indole-2-carboxylic acid, 3-bromo-5-methoxy-, ethyl ester
Ethyl 5-chloro-3-(4-chlorophenyl)-1,2,4-triazine-6-carboxylate
2-[3-(trifluoromethyl)benzylsulfonyl]thioacetamide
ethyl 3-bromo-5-(trifluoromethyl)pyridine-2-carboxylate
8-Bromo-4-(2-hydroxyethyl)-5-methoxy-2(1H)-quinolinone
([1-PHENYL-METH-(E)-YLIDENE]-AMINO)-ACETICACIDETHYLESTER
5-Bromo-N-(furan-2-ylmethyl)-3-nitropyridin-2-amine
ETHYL 2-BROMO-8-HYDROXYPYRIDO[3,2-D]PYRIMIDINE-7-CARBOXYLATE
Cythoate
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent D010575 - Pesticides > D007306 - Insecticides D016573 - Agrochemicals
3-(5-BROMO-PYRIDIN-3-YL)-[1,2,4]OXADIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
METHYL 3-AMINO-4-(PHENYLSULFONYL)THIOPHENE-2-CARBOXYLATE
3-(2-CHLORO-ACETYLAMINO)-4-METHOXY-BENZENESULFONYL CHLORIDE
5-Bromo-2-trifluoromethyl-nicotinic acid ethyl ester
ethyl 4-bromo-6-(trifluoromethyl)pyridine-2-carboxylate
4-Hydroxy-6-(trifluoromethoxy)-2-(trifluoromethyl)quinoline
(2S)-2-(4-BROMO-2,3,5,6-TETRAFLUOROPHENYL)PYRROLIDINE
(2-chloro-5-nitrophenyl)(2,6-difluorophenyl)Methanone
2-(6-Chloro-3-pyridazinyl)-2-(2,6-dichlorophenyl)acetonitrile
5-[(Aminooxy)methyl]-2-bromophenyl dihydrogen phosphate
5-bromo-N-(4-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
1-{[2-(2,4,6-Trichlorophenoxy)ethyl]amino}propan-2-ol
N-[phenyl(1,3-thiazol-2-yl)sulfamoyl]carbamimidate
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-thiophenesulfonamide
N-[[(5-chloro-2-pyridinyl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamide
4-chloro-N-(4-methyl-2-thiazolyl)-2-nitrobenzamide
N-(2,3-dichlorobenzylidene)-5-methyl-3-isoxazolecarbohydrazide
N(4)-acetylsulfathiazole
A sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a 1,3-thiazol-2-yl group at the nitrogen atom. It is a metabolite of sulfathiazole.
MPP+ (iodide)
MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT)[1][2].
