Exact Mass: 291.139
Exact Mass Matches: 291.139
Found 166 metabolites which its exact mass value is equals to given mass value 291.139,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
S-(2-Methylbutanoyl)-dihydrolipoamide
S-(2-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in isoleucine degradation. S-(2-Methylbutanoyl)-dihydrolipoamide is normally conjugated to a lysine residue of the methylpropanoyltransferase enzyme (E stands for enzyme). The structure shown here is the free form. Specifically S-(2-Methylbutanoyl)-dihydrolipoamide-E is the 2-methylbutanoyl thioester of the reduced lipoyllysine residue in dihydrolipoyllysine-residue (2-methylpropanoyl)transferase. [HMDB] S-(2-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in isoleucine degradation. S-(2-Methylbutanoyl)-dihydrolipoamide is normally conjugated to a lysine residue of the methylpropanoyltransferase enzyme (E stands for enzyme). The structure shown here is the free form. Specifically S-(2-Methylbutanoyl)-dihydrolipoamide-E is the 2-methylbutanoyl thioester of the reduced lipoyllysine residue in dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
S-(3-Methylbutanoyl)-dihydrolipoamide-E
S-(3-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in valine, leucine and isoleucine degradation(KEGG ID C15975 ). It is the second to last step in the synthesis of branched chain fatty acid and is converted from 3-methyl-hydroxybutyl-ThPP via the enzyme 2-oxoisovalerate dehydrogenase [EC:1.2.4.4]. It is then converted to 3-methylbutanoyl-CoA via the enzyme dihydrolipoyllysine-residue (2-methylpropanoyl)transferase[EC:2.3.1.168]. [HMDB] S-(3-Methylbutanoyl)-dihydrolipoamide-E is an intermediate in valine, leucine and isoleucine degradation(KEGG ID C15975 ). It is the second to last step in the synthesis of branched chain fatty acid and is converted from 3-methyl-hydroxybutyl-ThPP via the enzyme 2-oxoisovalerate dehydrogenase [EC:1.2.4.4]. It is then converted to 3-methylbutanoyl-CoA via the enzyme dihydrolipoyllysine-residue (2-methylpropanoyl)transferase[EC:2.3.1.168].
Benzhydramine HCl
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics D018926 - Anti-Allergic Agents Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].
(S)-Edulinine
(S)-Edulinine is found in pomes. (S)-Edulinine is an alkaloid from the bark of Casimiroa edulis (Mexican apple
2-hydroxy-3-methylbutanedioylcarnitine
2-hydroxy-3-methylbutanedioylcarnitine is an acylcarnitine. More specifically, it is an 2-hydroxy-3-methylbutanedioic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 2-hydroxy-3-methylbutanedioylcarnitine is therefore classified as a short chain AC. As a short-chain acylcarnitine 2-hydroxy-3-methylbutanedioylcarnitine is a member of the most abundant group of carnitines in the body, comprising more than 50\\% of all acylcarnitines quantified in tissues and biofluids (PMID: 31920980). Some short-chain carnitines have been studied as supplements or treatments for a number of diseases, including neurological disorders and inborn errors of metabolism. Carnitine acetyltransferase (CrAT, EC:2.3.1.7) is responsible for the synthesis of all short-chain and short branched-chain acylcarnitines (PMID: 23485643). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].
(2R,4S)-1-(Tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid
Befunolol
S - Sensory organs > S01 - Ophthalmologicals > S01E - Antiglaucoma preparations and miotics > S01ED - Beta blocking agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists C78283 - Agent Affecting Organs of Special Senses > C29705 - Anti-glaucoma Agent
syn-3-Isopropyl-6-(4-methoxybenzyl)-4-methylmorpholine-2,5-dione
Di-Me ester,N-tert-butyloxycarbonyl-2-Amino-3-hydroxypentanedioic acid
(Z)-1-pyrrolidin-1-yl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
3-isopropyl-6-(4-methoxybenzyl)-4-methylmorpholine-2,5-dione
methyl 5-acetamido-1,7-anhydro-3,5-dideoxy-beta-D-glycero-D-galacto-nonulopyranoside
Diphenhydramine Hydrochloride
Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].
S-(3-Methylbutanoyl)dihydrolipoyllysine
S-(2-Methylbutanoyl)dihydrolipoyllysine
(2R,4R)-tert-butyl 2-phenyl-4-vinylthiazolidine-3-carboxylate
N-METHYL-GAMMA-(2-METHYLPHENOXY)BENZENEPROPANAMINE HYDROCHLORIDE
2-(4-CARBOXY-PHENYL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
TRANS-1-BOC-2-PHENYL-PYRROLIDINE-3-CARBOXYLIC ACID
3-DIBENZYLAMINO-2-FLUOROPROPIONIC ACID BENZYL ESTER
2-((tert-Butyldimethylsilyloxy)methyl)furo[3,2-b]pyridine-6-carbaldehyde
N-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N-(1,3-thiazol-2-yl)ethane-1,2-diamine
2-(BOC-AMINO)-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLIC ACID
(2,4-DIMETHOXYBENZYLIDENE)CARBAMICACIDCYCLOHEXYLESTER
9-(4-chloro-3-methoxyphenyl)-3-azaspiro[5.5]undec-9-ene
Ethyl (1R,2S)-2-(Cbz-amino)cyclopentanecarboxylate
4-(2-(2,6-DIMETHYLPIPERIDIN-1-YL)-2-OXOETHOXY)BENZOIC ACID
N-Methyl-gamma-(2-methylphenoxy) phenylpropylamine hydrochloride
3-(2-HYDROXY-PHENYLCARBAMOYL)-1,2,2-TRIMETHYL-CYCLOPENTANECARBOXYLIC ACID
(2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID
N-BOC-5-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID
benzyl 2-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate
4-Methoxy-alpha-methyl-N-(phenylmethyl)benzeneethanamine hydrochloride
N-Methyl-N-(4-(2-biphenylyloxy)butyl)amine hydrochloride
(R)-(+)-2-Amino-3-methyl-1,1-diphenyl-1-butanol hydrochloride
3-Phenyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
(2R,5S)-1-(TERT-BUTOXYCARBONYL)-5-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID
(2R,4S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-4-phenylpyrrolidine-2-carboxylic acid
(3S,4R)-1-(TERT-BUTOXYCARBONYL)-4-PHENYLPYRROLIDINE-3-CARBOXYLIC ACID
3-[(2-methylpropan-2-yl)oxycarbonylamino]-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid
1-(tert-Butoxycarbonyl) 4-phenylpyrrolidine-3-carboxylic acid
ethyl 4-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)benzoate
(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol hydrochloride
8-((TERT-BUTOXYCARBONYL)AMINO)-5,6,7,8-TETRAHYDRONAPHTHALENE-2-CARBOXYLIC ACID
N-cyclopropyl-3-(1H-indazol-6-yl)-4-methylbenzamide
N-cyclopropyl-3-(1H-indazol-5-yl)-4-methylbenzamide
1-[(TERT-BUTYL)OXYCARBONYL]-4-PHENYLPYRROLINE-3-CARBOXYLIC ACID
Atomoxetine Hydrochloride
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C185721 - Norepinephrine Reuptake Inhibitor C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D049990 - Membrane Transport Modulators Atomoxetine (Tomoxetine) hydrochloride is a selective noradrenaline reuptake inhibitor with Ki values of 5 nM, 77 nM and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine hydrochloride is a potent Na+ channels (VGSCs) blocker. Atomoxetine hydrochloride can be used for attention-deficit hyperactivity disorder (ADHD) research[1][2][3].
(2R,4R)-1-[(2-methylpropan-2-yl)oxycarbonyl]-4-phenylpyrrolidine-2-carboxylic acid
(2S,4R)-Boc-4-Phenyl-pyrrolidine-2-carboxylic acid
3-(1-((Benzyloxy)carbonyl)piperidin-4-yl)propanoic acid
Ethyl (1S,2R)-2-(Cbz-amino)cyclopentanecarboxylate
2-Tert-Butyl 6-Methyl 3,4-Dihydroisoquinoline-2,6(1H)-Dicarboxylate
(s)-tert-butoxycarbonylamino-indan-1-yl-acetic acid
2-(TERT-BUTOXYCARBONYLAMINO)-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLIC ACID
4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-[1,1-biphenyl]-4-carbonitrile
Benzhydrol, α-(2-(dimethylamino)ethyl)-, hydrochloride
4-(1-((TERT-BUTOXYCARBONYL)AMINO)CYCLOBUTYL)BENZOIC ACID
1-[(2-methylpropan-2-yl)oxycarbonyl]-2-phenylpyrrolidine-3-carboxylic acid
(R)-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER 3-ETHYL ESTER
3-(4-CARBOXY-PHENYL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-(2-naphthyl)acetamide
2,4-Diamino-5-(3,4,5-trimethoxy-benzyl)-pyrimidin-1-ium
Befunolol
S - Sensory organs > S01 - Ophthalmologicals > S01E - Antiglaucoma preparations and miotics > S01ED - Beta blocking agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists C78283 - Agent Affecting Organs of Special Senses > C29705 - Anti-glaucoma Agent
