Exact Mass: 290.128
Exact Mass Matches: 290.128
Found 202 metabolites which its exact mass value is equals to given mass value 290.128,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Argininosuccinic acid disodium
Arginosuccinic acid is a basic amino acid. Some cells synthesize it from citrulline, aspartic acid and use it as a precursor for arginine in the urea cycle or Citrulline-NO cycle. The enzyme that catalyzes the reaction is argininosuccinate synthetase. Argininosuccinic acid is a precursor to fumarate in the citric acid cycle via argininosuccinate lyase. Defects in the argininosuccinate lyase enzyme can lead to argininosuccinate lyase deficiency, which is an inborn error of metabolism. Argininosuccinate (ASA) lyase deficiency results in defective cleavage of ASA. This leads to an accumulation of ASA in cells and an excessive excretion of ASA in urine (argininosuccinic aciduria). In virtually all respects, this disorder shares the characteristics of other urea cycle defects. The most important characteristic of ASA lyase deficiency is its propensity to cause hyperammonemia in affected individuals. ASA in affected individuals is excreted by the kidney at a rate practically equivalent to the glomerular filtration rate (GFR). Whether ASA itself causes a degree of toxicity due to hepatocellular accumulation is unknown; such an effect could help explain hyperammonemia development in affected individuals. Regardless, the name of the disease is derived from the rapid clearance of ASA in urine, although elevated levels of ASA can be found in plasma. ASA lyase deficiency is associated with high mortality and morbidity rates. Symptoms of ASA lyase deficiency include anorexia, irritability rapid breathing, lethargy and vomiting. Extreme symptoms include coma and cerebral edema. Arginosuccinic acid is a basic amino acid. Some cells synthesize it from citrulline, aspartic acid and use it as a precursor for arginine in the urea cycle or Citrulline-NO cycle. The enzyme that catalyzes the reaction is argininosuccinate synthetase. Argininosuccinic acid is a precursor to fumarate in the citric acid cycle via argininosuccinate lyase. Defects in the arginosuccinate lyase enzyme can lead to arginosuccinate lyase deficiency. Argininosuccinate (ASA) lyase deficiency results in defective cleavage of ASA. This leads to an accumulation of ASA in cells and an excessive excretion of ASA in urine (arginosuccinic aciduria). In virtually all respects, this disorder shares the characteristics of other urea cycle defects. The most important characteristic of ASA lyase deficiency is its propensity to cause hyperammonemia in affected individuals. ASA in affected individuals is excreted by the kidney at a rate practically equivalent to the glomerular filtration rate (GFR). Whether ASA itself causes a degree of toxicity due to hepatocellular accumulation is unknown; such an effect could help explain hyperammonemia development in affected individuals. Regardless, the name of the disease is derived from the rapid clearance of ASA in urine, although elevated levels of ASA can be found in plasma. ASA lyase deficiency is associated with high mortality and morbidity rates. Symptoms of ASA lyase deficiency include anorexia, irritability rapid breathing, lethargy and vomiting. Extreme symptoms include coma and cerebral edema. [HMDB] KEIO_ID A039; [MS2] KO008844 KEIO_ID A039
Trimethoprim
A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to pyrimethamine. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by sulfonamides and the trimethoprim-sulfamethoxazole combination is the form most often used. It is sometimes used alone as an antimalarial. Trimethoprim resistance has been reported. [PubChem] Trimethoprim. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=738-70-5 (retrieved 2024-07-09) (CAS RN: 738-70-5). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Carbinoxamine
Carbinoxamine, also known as carbinoxamine maleate or clistin, is a member of the class of compounds known as benzylethers. Benzylethers are aromatic ethers with the general formula ROCR (R = alkyl, aryl; R=benzene). Carbinoxamine is practically insoluble (in water) and a very strong basic compound (based on its pKa). Carbinoxamine can be found in barley and garden onion, which makes carbinoxamine a potential biomarker for the consumption of these food products. Carbinoxamine can be found primarily in blood and urine. In humans, carbinoxamine is involved in the carbinoxamine h1-antihistamine action. Carbinoxamine is a non-carcinogenic (not listed by IARC) potentially toxic compound. Carbinoxamine is a drug which is used for symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis, as well as allergic conjunctivitis caused by foods and inhaled allergens. also for the relief of allergic reactions to blood or plasma, and the symptomatic management of mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Carbinoxamine (Clistin, Palgic, Rondec, Rhinopront) is a antihistamine and anticholinergic agent. It was first launched in the United States by the McNeil Corporation under the brand name Clistin. It is now available under the brand name Palgic as 4 mg tablets or 4 mg/5 mL liquid. It is approved by the U.S. Food and Drug Administration (FDA) (specifically at the 4 mg dose/strength) for hay fever (a.k.a. allergic rhinitis, SAR and PAR); vasomotor rhinitis; mild urticaria; angioedema, dermatographism and allergic conjunctivitis. Carbinoxamine is a histamine antagonist, specifically an H1-antagonist. The maleic acid salt of the levorotatory isomer is sold as the prescription drug rotoxamine . Carbinoxamine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. Carbinoxamines anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown (DrugBank). Carbinoxamine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. Carbinoxamines anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown (T3DB). Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state do not use in children under 4 years of age in order to prevent and reduce misuse, as many unapproved carbinoxamine-containing preparations contained inappropriate labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and the use in children under 2 years of age), which can potentially cause serious health risks. R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AA - Aminoalkyl ethers D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
Benomyl
Benomyl is an Agricultural and horticultural systemic fungicide mainly used on rice and soybea D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents D016573 - Agrochemicals D010575 - Pesticides
trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene
This compound belongs to the family of Phenanthrenes and Derivatives. These are polycyclic compounds containing a phenanthrene moiety, which is a tricyclic aromatic compound with three non-linearly fused benzene.
trans-5,6-Dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracene
This compound belongs to the family of Phenanthrenes and Derivatives. These are polycyclic compounds containing a phenanthrene moiety, which is a tricyclic aromatic compound with three non-linearly fused benzene.
2-(4-Methyl-3-pentenyl)anthraquinone
2-(4-Methyl-3-pentenyl)anthraquinone is found in fats and oils. 2-(4-Methyl-3-pentenyl)anthraquinone is isolated from the hairy root culture of Sesamum indicum (sesame). Isolated from the hairy root culture of Sesamum indicum (sesame). 2-(4-Methyl-3-pentenyl)anthraquinone is found in fats and oils.
N2-(3-Carboxy-2-hydroxy-1-oxopropyl)arginine
N2-(3-Carboxy-2-hydroxy-1-oxopropyl)arginine is found in pomes. N2-(3-Carboxy-2-hydroxy-1-oxopropyl)arginine is a constituent of the seeds of Vicia faba and the shoots of apple and pear trees. Constituent of the seeds of Vicia faba and the shoots of apple and pear trees. N2-(3-Carboxy-2-hydroxy-1-oxopropyl)arginine is found in pomes and pulses.
N2-(3-Hydroxysuccinoyl)arginine
N2-(3-Hydroxysuccinoyl)arginine is found in pomes. N2-(3-Hydroxysuccinoyl)arginine is a constituent of the shoots of apple and pear trees. Constituent of the shoots of apple and pear trees. N2-(3-Hydroxysuccinoyl)arginine is found in pomes.
Glycine, N-[1-(phenylacetyl)-L-prolyl]-
(3R,4R)-7,12-Dimethyl-3,4-dihydrobenzo(a)anthracene-3,4-diol
3-[2-(3,4,5-trimethoxyphenyl)ethenyl]-4,5-dihydro-1H-pyridazin-6-one
Thioacetic acid S-[[4,4a,7,8,8a,9-hexahydro-9,9-dimethylnaphtho[2,3-b]furan]-6-yl]methyl ester
Thioacetic acid S-[[4,4a,5,6,8a,9-hexahydro-4,4-dimethylnaphtho[2,3-b]furan]-7-yl]methyl ester
N-(4-Chlor-benzyl)-N,N-dimethyl-N-pyrimidin-2-yl-aethylendiamin|N-(4-chloro-benzyl)-N,N-dimethyl-N-pyrimidin-2-yl-ethylenediamine|solamin
Me glycoside,2,3-O-isopropulidene,4-Ac,6-Me-Talose,
4-[2-(5-Hydroxy-1H-indole-3-yl)ethylamino]-4-oxobutyric acid methyl ester
(3S,8S)-cordiarimide B|cordiarimide B|N-[(S)-1-[(S)-2-hydroxy-2-phenylethyl]-2,6-dioxopiperidin-3-yl]acetamide
n-(6-hydroxyindol-3-ylacetyl)-valine
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids
Trimethioprim
Trimethoprim. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=738-70-5 (retrieved 2024-07-09) (CAS RN: 738-70-5). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Argininosuccinic acid
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; KDZOASGQNOPSCU_STSL_0151_Argininosuccinic acid_8000fmol_180506_S2_LC02_MS02_235; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
1-(1-phenylmethoxycarbonylazetidin-3-yl)azetidine-3-carboxylic acid
ethyl 1-(aminomethyl)-6,8-dimethoxyisoquinoline-4-carboxylate
(3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine hydrochloride
1-TERT-BUTYL 5-METHYL 3-METHYL-1H-INDAZOLE-1,5-DICARBOXYLATE
N-METHYL-N-[4-(PIPERIDIN-1-YLMETHYL)BENZYL]AMINE DIHYDROCHLORIDE
1-[(4-methylpiperidin-1-yl)sulfonyl]piperidine-4-carboxylic acid
Ethyl 4-hydroxy-1-isopropyl-7-methyl-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate
ETHYL 4-HYDROXY-7-METHYL-2-OXO-1-PROPYL-1,2-DIHYDRO-1,8-NAPHTHYRIDINE-3-CARBOXYLATE
1-(2-HYDROXY-2-METHYLPROPYL)-5-METHYL-3-OXO-2-PHENYL-2,3-DIHYDROPYRAZOLE-4-CARBOXYLIC ACID
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-thienylmethyl)-1H-pyrazole
2-TERT-BUTOXYCARBONYLAMINO-3-(4-CYANO-PHENYL)-PROPIONIC ACID
1-Ethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyrid ine-5-carboxylic acid
Diethyl 2,6-dimethyl-1H-pyrrolo[2,3-b]pyridine-3,5-dicarboxylate
3-(4-chlorophenyl)-N,N-dimethyl-3-(2-pyridyl)propan-1-amine oxide
benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride(dr>98/2)
3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride (1:2),(3S,4R)-
2-Propenoic acid 4-[(4-propylphenyl)ethynyl]phenyl ester
Tris(trimethylsilyl)silyloxyethylene,Vinyloxytris(trimethylsilyl)silane
1-CYANO-2-ETHOXYCARBONYL-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE
1-(7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d][1,3]dioxol-5-yl)ethanone
N-[(4-methyl-5-phenyldiazenyl-2-imidazolylidene)amino]aniline
Pentanedioic acid, 3-methyl-, bis(trimethylsilyl) ester
(2R)-2-[[N-[(4S)-4-amino-4-carboxybutyl]carbamimidoyl]amino]butanedioic acid
3-Hydroxymethyl-5-aziridinyl-1methyl-2-[1h-indole-4,7-dione]-propanol
Methyl (3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoate
2-[[2-(6-Hydroxy-1H-indol-3-yl)acetyl]amino]-3-methylbutanoic acid
(2S)-3-methyl-2-[[2-(2-oxo-1,3-dihydroindol-3-yl)acetyl]amino]butanoic acid
3-chloro-N-methyl-N-[4-(1-pyrrolidinyl)but-2-ynyl]benzamide
N-(2-oxoazepan-3-yl)-N-(pyridin-3-ylmethyl)oxamide
1-(2,3-Dimethyl-6-quinoxalinyl)-3-(3-hydroxypropyl)thiourea
3,5-dimethyl-N-[(E)-(2,4,5-trimethoxyphenyl)methylidene]-4H-1,2,4-triazol-4-amine
6-methoxy-2-(3-phenyl-2-propenylidene)-3,4-dihydro-1(2H)-naphthalenone
ethyl 3-amino-7,7-dimethyl-7,8-dihydro-5H-furo[2,3-b]pyrano[3,4-e]pyridine-2-carboxylate
7-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-3-oxoheptanoic acid
(6R)-6-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-3-oxoheptanoic acid
tert-butyl N-[(E)-[(E)-3-(1,3-benzodioxol-5-yl)prop-2-enylidene]amino]carbamate
1-Phenyl-1-(5-methyl-3-phenyl-2-furyl)acetone (3,3,3-D3)
2-(Phenylethynyl)-1,1,1,2,3,3,3-heptamethyltrisilane
2-(3-Chloropropionyl)-5,7-dimethyl-1,2,3,4-tetrahydropyrimido(1,6-A)indole
1,3-Dimethyl-4,6-diphenyl-2-oxabicyclo(4.1.0)hept-3-EN-5-one
carbinoxamine
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AA - Aminoalkyl ethers D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist
trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene
trans-5,6-Dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracene
Benlate
D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents D016573 - Agrochemicals D010575 - Pesticides
M4 mAChR agonist-1
M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4[1].
(7s,8r)-5-ethyl-8,11-dihydroxy-12-methoxy-3,9-diazatricyclo[8.4.0.0³,⁷]tetradeca-1(14),4,10,12-tetraen-2-one
1,4-bis-benzyloxy-benzene
{"Ingredient_id": "HBIN001390","Ingredient_name": "1,4-bis-benzyloxy-benzene","Alias": "NA","Ingredient_formula": "C20H18O2","Ingredient_Smile": "C1=CC=C(C=C1)COC2=CC=C(C=C2)OCC3=CC=CC=C3","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "2436","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2-(4-methylpent-3-enyl)anthraquinone
{"Ingredient_id": "HBIN004474","Ingredient_name": "2-(4-methylpent-3-enyl)anthraquinone","Alias": "NA","Ingredient_formula": "C20H18O2","Ingredient_Smile": "CC(=CCCC1=CC2=C(C=C1)C(=O)C3=CC=CC=C3C2=O)C","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "14655","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
