Exact Mass: 284.1395238
Exact Mass Matches: 284.1395238
Found 170 metabolites which its exact mass value is equals to given mass value 284.1395238,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Promethazine
Promethazine is only found in individuals that have used or taken this drug. It is a phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals. [PubChem]Like other H1-antagonists, promethazine competes with free histamine for binding at H1-receptor sites in the GI tract, uterus, large blood vessels, and bronchial muscle. The relief of nausea appears to be related to central anticholinergic actions and may implicate activity on the medullary chemoreceptor trigger zone. D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AD - Phenothiazine derivatives D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent > C740 - Phenothiazine D003879 - Dermatologic Agents > D000982 - Antipruritics CONFIDENCE standard compound; INTERNAL_ID 2505 CONFIDENCE standard compound; INTERNAL_ID 8490 D018926 - Anti-Allergic Agents
Promazine
C17H20N2S (284.13471200000004)
Promazine is only found in individuals that have used or taken this drug. It is a phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. [PubChem]Promazine is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors. Promazines antipsychotic effect is due to antagonism at dopamine and serotonin type 2 receptors, with greater activity at serotonin 5-HT2 receptors than at dopamine type-2 receptors. This may explain the lack of extrapyramidal effects. Promazine does not appear to block dopamine within the tubero-infundibular tract, explaining the lower incidence of hyperprolactinemia than with typical antipsychotic agents or risperidone. Antagonism at muscarinic receptors, H1-receptors, and alpha(1)-receptors also occurs with promazine. N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics > N05AA - Phenothiazines with aliphatic side-chain D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent > C740 - Phenothiazine D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics
Allogibberic acid
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D005875 - Gibberellins
16-Oxoestrone
Estrone (also oestrone) is an estrogenic hormone secreted by the ovary. Its molecular formula is C18H22O2. estrone has a melting point of 254.5 degrees Celsius. estrone is one of the three estrogens, which also include estriol and estradiol. estrone is the least prevalent of the three hormones, estradiol being prevalent almost always in a female body, estriol being prevalent primarily during pregnancy. estrone sulfate is relevant to health and disease due to its conversion to estrone sulfate, a long-lived derivative of estrone. estrone sulfate acts as a pool of estrone which can be converted as needed to the more active estradiol. [HMDB] Estrone (also oestrone) is an estrogenic hormone secreted by the ovary. Its molecular formula is C18H22O2. estrone has a melting point of 254.5 degrees Celsius. estrone is one of the three estrogens, which also include estriol and estradiol. estrone is the least prevalent of the three hormones, estradiol being prevalent almost always in a female body, estriol being prevalent primarily during pregnancy. estrone sulfate is relevant to health and disease due to its conversion to estrone sulfate, a long-lived derivative of estrone. estrone sulfate acts as a pool of estrone which can be converted as needed to the more active estradiol.
alpha,alpha-diethyl-3,4,4-stilbenetriol
(+)-Larreatricin
An antiviral lignan isolated from the creosote bush, Larrea tridentata, which consists of a 3,4-dimethyltetrahydrofuran skeleton substituted by 4-hydroxyphenyl groups at positions 2 and 5 (the 2R,3R,4S,5R stereoisomer).
(S)-17-Hydroxy-9,11,13,15-octadecatetraynoic acid
(S)-17-Hydroxy-9,11,13,15-octadecatetraynoic acid is found in nuts. (S)-17-Hydroxy-9,11,13,15-octadecatetraynoic acid is isolated from Coula edulis. Isolated from Coula edulis. (S)-17-Hydroxy-9,11,13,15-octadecatetraynoic acid is found in nuts.
Estrone-2,3-quinone
Estrogen 2,3- and 3,4-quinones are reactive species toward nucleophiles and Michael acceptors. As such, they can bind to DNA and induce cellular damages.Tumors may arise in cells covalently damaged by the free radicals or by the quinones and stimulated to proliferate by hormone receptor-mediated. processes. This hypothesis is supported by the correlation between quinone formation, 8-hydroxylation of guanine bases of DNA and tumor incidence of 4- versus 2-hydroxylated estrogen metabolites. Moreover, estrone-3,4-quinone, but not. estrone-2,3-quinone, induced liver tumors in mice. Estrogen 2,3- and 3,4-quinones are reactive species toward nucleophiles and Michael acceptors. As such, they can bind to DNA and induce cellular damages.Tumors may arise in cells covalently damaged by the free radicals or by the quinones and stimulated to proliferate by hormone receptor-mediated
Estrone-3,4-quinone
Estrogen 2,3- and 3,4-quinones are reactive species toward nucleophiles and Michael acceptors. As such, they can bind to DNA and induce cellular damages.Tumors may arise in cells covalently damaged by the free radicals or by the quinones and stimulated to proliferate by hormone receptor-mediated. processes. This hypothesis is supported by the correlation between quinone formation, 8-hydroxylation of guanine bases of DNA and tumor incidence of 4- versus 2-hydroxylated estrogen metabolites. Moreover, estrone-3,4-quinone, but not. estrone-2,3-quinone, induced liver tumors in mice. Estrogen 2,3- and 3,4-quinones are reactive species toward nucleophiles and Michael acceptors. As such, they can bind to DNA and induce cellular damages.Tumors may arise in cells covalently damaged by the free radicals or by the quinones and stimulated to proliferate by hormone receptor-mediated
3-(4-Carboxybenzylidene)camphor
N-Desmethyltrimeprazine
C17H20N2S (284.13471200000004)
Siguazodan
C14H16N6O (284.13855259999997)
1-(4-Hydroxyphenyl)-2-[4-(1-propenyl)-phenoxyl]-1-propanol
1-O,3-O-[1,4-Phenylene(dimethylmethylene)1,4-phenylene]glycerol
(2R,3R)-2,3-Dihydro-2-(4-hydroxyphenyl)-5-(3-hydroxypropyl)-3-methylbenzofuran
N,N-Dimethyl-N,N-dibenzylthioharnstoff
C17H20N2S (284.13471200000004)
6-Methoxy-4-phenyl-2,3-dihydro-3,3-dimethylbenzofuran-2-methanol
3,4-dihydro-5-methoxy-2,2-dimethyl-7-(4-hydroxyphenyl)-2H-1-benzopyran|garcibenzopyran
10-methoxy-8-methyl-3-(prop-1-en-2-yl)-3,4-dihydro-1H-benzo[h]isochromen-4-ol|cichorin A
9,10-Dihydro-4-(1-hydroxyethyl)-2,8-dimethylphenanthrene-1,7-diol
5-methoxy-4-(3-methyl-2-butenyl)-[1,1-biphenyl]-3,4-diol|garcibiphenyl B
Ac-(2R*,6R*,1E,3E,9E)-form-Tetrahydro-6-(1,3,9-undecatriene-5,7-diynyl)-2H-pyran-2-ol,
(2R,3R,2R)-2,3-dihydro-2-(4-hydroxyphenyl)-5-(2-hydroxypropyl)-3-methylbenzofuran
9,10-Dihydro-5-(1-hydroxyethyl)-1,7-dimethylphenanthrene-2,6-diol
TBS-Corey Lactone Aldehyde
promethazine
C17H20N2S (284.13471200000004)
D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AD - Phenothiazine derivatives D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent > C740 - Phenothiazine D003879 - Dermatologic Agents > D000982 - Antipruritics D018926 - Anti-Allergic Agents
2-Furanpropionic acid, tetrahydro-a-(1-naphthylmethyl)-
Minquartynoic acid
A straight-chain, C18 polyunsaturated fatty acid having four conjugated C#C bonds at positions 9, 11, 13 and 15 as well as an (S)-hydroxy group at position 17.
ST 18:5;O3
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
1,3-Propanediol, 2,2-methylenebis(oxymethylene)bis2-(hydroxymethyl)-
Propanoic acid,2-[4-(1-methyl-1-phenylethyl)phenoxy]-
5-tert-butylsulfonyl-2-pyrrolidin-1-ylpyrimidin-4-amine
Siguazodan
C14H16N6O (284.13855259999997)
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor
di[4-(dimethylamino)phenyl]methanethione
C17H20N2S (284.13471200000004)
Methyl 3-(2-methoxy-5-methylphenyl)-3-phenylpropionate
5-(ISOPROPYLSULFONYL)-2-PIPERIDINOPYRIMIDIN-4-AMINE
8-(TERT-BUTOXYCARBONYL)-1-OXA-2,8-DIAZASPIRO[4.5]DEC-2-ENE-3-CARBOXYLIC ACID
Benzenepropanoic acid, 2-methyl-4-(phenylmethoxy)-, methyl ester
tert-butyl 3-(3-amino-1H-pyrazol-5-yl)piperidine-1-carboxylate
(S)-Ethyl 5-(1-((tert-butoxycarbonyl)amino)ethyl)oxazole-4-carboxylate
1-(3-chlorophenyl)-2-[[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]amino]propan-1-one,hydrochloride
7-(tert-butoxycarbonyl)-1-oxa-2,7-diazaspiro[4.5]dec-2-ene-3-carboxylic acid
4,4-BIS(DIMETHYLAMINO)THIOBENZOPHENONE
C17H20N2S (284.13471200000004)
(2R,5R)-2-tert-butyl-3,5-dimethylimidazolidin-4-one trifluoroacetic acid salt
C2HF3O2*C9H18N2O (284.13476999999995)
2-[4-(2,2-DIFLUORO-ETHOXY)-PHENYL]-4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLANE
Estra-1,5(10)-diene-3,4,17-trione
An o-quinone resulting from the formal oxidation of the dihydroxyphenyl moiety of 4-hydroxyestrone.
Isopromethazine
C17H20N2S (284.13471200000004)
D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists D003879 - Dermatologic Agents > D000982 - Antipruritics D018926 - Anti-Allergic Agents
16-Oxoestrone
Estrone (also oestrone) is an estrogenic hormone secreted by the ovary. Its molecular formula is C18H22O2. estrone has a melting point of 254.5 degrees Celsius. estrone is one of the three estrogens, which also include estriol and estradiol. estrone is the least prevalent of the three hormones, estradiol being prevalent almost always in a female body, estriol being prevalent primarily during pregnancy. estrone sulfate is relevant to health and disease due to its conversion to estrone sulfate, a long-lived derivative of estrone. estrone sulfate acts as a pool of estrone which can be converted as needed to the more active estradiol. [HMDB] Estrone (also oestrone) is an estrogenic hormone secreted by the ovary. Its molecular formula is C18H22O2. estrone has a melting point of 254.5 degrees Celsius. estrone is one of the three estrogens, which also include estriol and estradiol. estrone is the least prevalent of the three hormones, estradiol being prevalent almost always in a female body, estriol being prevalent primarily during pregnancy. estrone sulfate is relevant to health and disease due to its conversion to estrone sulfate, a long-lived derivative of estrone. estrone sulfate acts as a pool of estrone which can be converted as needed to the more active estradiol. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
4-[(E)-(4,7,7-trimethyl-3-oxo-2-bicyclo[2.2.1]heptanylidene)methyl]benzoic acid
Estra-1(10),4-diene-2,3,17-trione
An o-quinone resulting from the formal oxidation of the dihydroxyphenyl moiety of 2-hydroxyestrone. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
(-)-Larreatricin
A lignan that consists of a 3,4-dimethyloxolane ring substituted by 4-hydroxyphenyl groups at positions 2 and 5 respectively (the 2S,3R,4S,5S-stereoisomer). Isolated from the roots of Krameria lappacea, it exhibits anti-inflammatory activity.
Meso-3,3-Didemethoxynectandrin B
A lignan that consists of a 3,4-dimethyloxolane ring substituted by 4-hydroxyphenyl groups at positions 2 and 5 respectively (the 2R,3R,4S,5S-stereoisomer). Isolated from the roots of Krameria lappacea, it exhibits anti-inflammatory activity.
threo-(7S,8R)-1-(4-hydroxyphenyl)-2-[4-(E)-propenylphenoxy]-propan-1-ol
A natural product found in Ribes fasciculatum var chinense.
pomecin A
A polyunsaturated fatty acid that is tetradec-9-ene-11,13-diynoic acid in which the terminal acetylenic hydrogen is replaced by a 2-furyl group. Shows potent and broad-spectrum activity in vitro against Candida, Aspergillus, and Trichophyton spp.,
alpha,alpha-diethyl-3,4,4-stilbenetriol
(3aR,4R,5R,6aS)-5-(tert-butyldimethylsilyloxy)-2-oxohexahydro-2H-cyclopenta[b]furan-4-carbaldehyde
2-[3-carboxy-3-(dimethylamino)propyl]-L-histidine
C12H20N4O4 (284.14844800000003)
A L-histidine derivative that is L-histidine substituted at poisition 2 (on the imidazole ring) by a 3-carboxy-3-(dimethylamino)propyl group.
4-{5-[(2S)-2-azaniumyl-2-carboxylatoethyl]-1H-imidazol-2-yl}-2-(dimethylazaniumyl)butanoate
C12H20N4O4 (284.14844800000003)
[(3aS,4R,10S,10aS)-2,6-diamino-10-hydroxy-3a,4,5,8,9,10-hexahydro-1H-pyrrolo[1,2-c]purin-7-ium-4-yl]methyl carbamate
C10H18N7O3+ (284.14710579999996)
5-Hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-14,17-dione
Methyl (2R)-2-(N-((4S)-4-(1-methylethyl)-2-oxazolidinone-3-carbamoyl)amino)-4-pentenoate
promazine
C17H20N2S (284.13471200000004)
N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics > N05AA - Phenothiazines with aliphatic side-chain D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent > C740 - Phenothiazine D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics
16-Ketoestrone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
2-[3-carboxylato-3-(dimethylammonio)propyl]-L-histidine dizwitterion
C12H20N4O4 (284.14844800000003)
An amino acid zwitterion obtained by transfer of protons from the amino to the carboxy groups of 2-[3-carboxy-3-(dimethylamino)propyl]-L-histidine.
4-(5-methoxy-2,2-dimethyl-3,4-dihydro-1-benzopyran-7-yl)phenol
8-(3,6-dimethylhepta-2,5-dien-1-yl)-7-hydroxychromen-2-one
4-{1-hydroxy-2-[4-(prop-1-en-1-yl)phenoxy]propyl}phenol
{[(3e)-5-hydroxy-5-(hydroxymethyl)-2-methoxy-3-[(1e)-prop-1-en-1-ylimino]cyclohex-1-en-1-yl]amino}acetic acid
4-[(1s)-1-hydroxyethyl]-2,8-dimethyl-9,10-dihydrophenanthrene-1,7-diol
4-[(2s,3s,4r,5r)-5-(4-hydroxyphenyl)-3,4-dimethyloxolan-2-yl]phenol
{[(3e,5s)-5-hydroxy-5-(hydroxymethyl)-2-methoxy-3-[(1z)-prop-1-en-1-ylimino]cyclohex-1-en-1-yl]amino}acetic acid
6,10-dihydroxy-4,4,8-trimethyl-1h,2h,3h-cyclohepta[a]naphthalen-9-one
4-(1-hydroxyethyl)-2,8-dimethyl-9,10-dihydrophenanthrene-1,7-diol
1,3-di-o-[2',2'-di-(p-phenylene)isopropylidene]glycerol
{"Ingredient_id": "HBIN001214","Ingredient_name": "1,3-di-o-[2',2'-di-(p-phenylene)isopropylidene]glycerol","Alias": "NA","Ingredient_formula": "C18H20O3","Ingredient_Smile": "CC1(C2=CC=C(C=C2)OCC(COC3=CC=C1C=C3)O)C","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "5480","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
1-hydroxyethyl)-2,6-dihydroxy-1,7-dimethyl-9,10-dihydrophenanthrene
{"Ingredient_id": "HBIN002653","Ingredient_name": "1-hydroxyethyl)-2,6-dihydroxy-1,7-dimethyl-9,10-dihydrophenanthrene","Alias": "NA","Ingredient_formula": "C18H20O3","Ingredient_Smile": "NA","Ingredient_weight": "284.38","OB_score": "42.31360231","CAS_id": "NA","SymMap_id": "SMIT00908","TCMID_id": "NA","TCMSP_id": "MOL007915","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
5-(1-hydroxyethyl)-2,6-dihydroxy-1,7-dimethyl-9,10-dihydrophenanthrene
{"Ingredient_id": "HBIN010962","Ingredient_name": "5-(1-hydroxyethyl)-2,6-dihydroxy-1,7-dimethyl-9,10-dihydrophenanthrene","Alias": "NA","Ingredient_formula": "C18H20O3","Ingredient_Smile": "CC1=C(C(=C2C(=C1)CCC3=C2C=CC(=C3C)O)C(C)O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "10100","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
5-(1-hydroxyethyl)-2,8-dihydroxy-1,7-dimethyl-9,10-dihydrophenanthrene
{"Ingredient_id": "HBIN010963","Ingredient_name": "5-(1-hydroxyethyl)-2,8-dihydroxy-1,7-dimethyl-9,10-dihydrophenanthrene","Alias": "NA","Ingredient_formula": "C18H20O3","Ingredient_Smile": "CC1=C(C=CC2=C1CCC3=C2C(=CC(=C3C)O)C(C)O)O","Ingredient_weight": "284.38","OB_score": "19.37313925","CAS_id": "NA","SymMap_id": "SMIT00723","TCMID_id": "10101","TCMSP_id": "MOL007916","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
9,10-dihydro-1,7-dihydroxy-4-(1-hydroxyethyl)-2,8-dimethylphenanthrene
{"Ingredient_id": "HBIN013925","Ingredient_name": "9,10-dihydro-1,7-dihydroxy-4-(1-hydroxyethyl)-2,8-dimethylphenanthrene","Alias": "NA","Ingredient_formula": "C18H20O3","Ingredient_Smile": "NA","Ingredient_weight": "284.35","OB_score": "NA","CAS_id": "147850-91-7","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7316","PubChem_id": "NA","DrugBank_id": "NA"}
9,10-dihydro-2,6-dihydroxy-5-(1-hydroxyethyl)-1,7-dimethylphenanthrene
{"Ingredient_id": "HBIN013927","Ingredient_name": "9,10-dihydro-2,6-dihydroxy-5-(1-hydroxyethyl)-1,7-dimethylphenanthrene","Alias": "NA","Ingredient_formula": "C18H20O3","Ingredient_Smile": "NA","Ingredient_weight": "284.35","OB_score": "NA","CAS_id": "147850-89-3","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7314","PubChem_id": "NA","DrugBank_id": "NA"}
9,10-dihydro-2,7-dihydroxy-4-(1-hydroxyethyl)-1,8-dimethylphenanthrene
{"Ingredient_id": "HBIN013931","Ingredient_name": "9,10-dihydro-2,7-dihydroxy-4-(1-hydroxyethyl)-1,8-dimethylphenanthrene","Alias": "NA","Ingredient_formula": "C18H20O3","Ingredient_Smile": "NA","Ingredient_weight": "284.35","OB_score": "NA","CAS_id": "199597-54-1","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7310","PubChem_id": "NA","DrugBank_id": "NA"}
9,10-dihydro-7-hydroxy-2-methoxy-1,8-dimethyl-4-phenanthrenemethanol
{"Ingredient_id": "HBIN013940","Ingredient_name": "9,10-dihydro-7-hydroxy-2-methoxy-1,8-dimethyl-4-phenanthrenemethanol","Alias": "NA","Ingredient_formula": "C18H20O3","Ingredient_Smile": "NA","Ingredient_weight": "284.35","OB_score": "NA","CAS_id": "169134-57-0","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7302","PubChem_id": "NA","DrugBank_id": "NA"}