Exact Mass: 248.1558
Exact Mass Matches: 248.1558
Found 181 metabolites which its exact mass value is equals to given mass value 248.1558,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Pindolol
Pindolol is only found in individuals that have used or taken this drug. It is a moderately lipophilic beta blocker (adrenergic beta-antagonists). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)Pindolol non-selectively blocks beta-1 adrenergic receptors mainly in the heart, inhibiting the effects of epinephrine and norepinephrine resulting in a decrease in heart rate and blood pressure. By binding beta-2 receptors in the juxtaglomerular apparatus, Pindolol inhibits the production of renin, thereby inhibiting angiotensin II and aldosterone production and therefore inhibits the vasoconstriction and water retention due to angiotensin II and aldosterone, respectively. C - Cardiovascular system > C07 - Beta blocking agents > C07A - Beta blocking agents > C07AA - Beta blocking agents, non-selective C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents CONFIDENCE standard compound; INTERNAL_ID 4098 CONFIDENCE standard compound; INTERNAL_ID 2663 Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33nM).
Bunitrolol
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
ACETIC ACID, (2-(3,6-DIAMINO-5-HYDROXYHEXANOYL)-1-METHYLHYDRAZINO)-
1COOH-2But-A7EO2
Literature spectrum; CONFIDENCE Tentative identification: isomers possible (Level 3); Could be alkyl homologue of given structure; Digitised from figure: approximate intensities
MLS001048956-01!1-(6-methylsulfinylhexyl)-3-propan-2-ylurea
pindolol
C - Cardiovascular system > C07 - Beta blocking agents > C07A - Beta blocking agents > C07AA - Beta blocking agents, non-selective C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33nM).
2-Piperidinecarboxamide, N-(3-hydroxy-2,6-dimethylphenyl)-, (S)-
TERT-BUTYL (1,2,3,4-TETRAHYDROQUINOLIN-3-YL)CARBAMATE
1-(n-benzyloxycarbonyl)-trans-cyclohexane-1,2-diamine
butan-1-ol,2-methyloxirane,oxirane,prop-2-enoic acid
tert-butyl 5,6,7,8-tetrahydroquinolin-8-ylcarbamate
3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheno l
ethyl 1-(pyridin-2-ylmethyl)piperidine-4-carboxylate
TERT-BUTYL (1,2,3,4-TETRAHYDROQUINOLIN-4-YL)CARBAMATE
N-(4-HYDROXY-3-(1-PIPERIDINYLMETHYL) PHENYL)ACETAMIDE
N-(cyclopropylmethyl)-3-methyl-4-nitro-N-propylaniline
TERT-BUTYL 4-AMINO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE
4-HYDROXY-3,5-DIMETHYLPHENYLBORONIC ACID PINACOL ESTER
3-AMINO-1-BENZYL-PIPERIDINE-3-CARBOXYLIC ACID METHYL ESTER
9,10-Dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrazino[2,1-a]isoquinoline
2-Methyl-2-propanyl 5,6,7,8-tetrahydro-9H-pyrido[2,3-b]azepine-9- carboxylate
Carbamic acid, (4-aminocyclohexyl)-, phenylmethyl ester (9CI)
tert-Butyl 4-amino-3,4-dihydroquinoline-1(2H)-carboxylate
1-(4-(4-AMINO-3-METHOXYPHENYL)PIPERIDIN-1-YL)ETHANONE
4-(4-HYDROXY-PIPERIDIN-1-YL)-BENZIMIDIC ACID ETHYL ESTER
4-(Hydroxymethyl)-3-methylphenylboronic Acid Pinacol Ester
4-Amino-3-methyl-1-piperidinecarboxylic acid benzyl ester
1-Pyrrolidinecarboxylic acid, 3-(4-pyridinyl)-, 1,1-dimethylethyl ester
tert-Butyl 5-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate
TERT-BUTYL (1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL)CARBAMATE
3-(4-METHYL-[1,4]DIAZEPAN-1-YLMETHYL)-BENZOIC ACID
benzyl (3R)-3-(dimethylamino)pyrrolidine-1-carboxylate
2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol
Acetamide,N,N-[(4,6-dimethyl-1,3-phenylene)bis(methylene)]bis- (9CI)
ETHYL 4-(PYRIDIN-4-YLMETHYL)PIPERAZINE-1-CARBOXYLATE
N-[4-[3-(dimethylamino)-2-methylpropanoyl]phenyl]acetamide
2-ethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
1-(4-(4-(2-Hydroxyethyl)piperazin-1-yl)phenyl)ethanone
(4-ETHOXY-BENZYL)-(1-METHYL-1H-BENZOIMIDAZOL-5-YL)-AMINE
tert-butyl 3-(5-methylpyridin-2-yl)azetidine-1-carboxylate
5-AMino-2-Methyl-piperidine-1-carboxylic acid benzyl ester
tert-butyl 7-(aminomethyl)-2,3-dihydroindole-1-carboxylate
7-Methyl-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester
benzyl (3S)-3-(dimethylamino)pyrrolidine-1-carboxylate
L-NMMA acetate
C471 - Enzyme Inhibitor > C29574 - Nitric Oxide Synthase Inhibitor
Piperidin-3-ylmethyl-carbamic acid benzyl ester hydrochloride
tert-butyl 5-(aminomethyl)-2,3-dihydro-1H-isoindole-2-carboxylate
(1,2,3,4-TETRAHYDRO-ISOQUINOLIN-5-YL)-CARBAMIC ACID TERT-BUTYL ESTER
tert-Butyl 7-amino-3,4-dihydroquinoline-1(2H)-carboxylate
TERT-BUTYL 1,2,3,4-TETRAHYDROISOQUINOLIN-7-YLCARBAMATE
(2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol
(2S,5R)-Benzyl 5-amino-2-methylpiperidine-1-carboxylate hydrochloride
1-Piperidinecarboxylic acid, 3-amino-2-methyl-, phenylmethyl ester, (2R,3R)-
3-Methoxy-4-methylphenylboronic acid, pinacol ester
2-(3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)ETHANOL
1-Piperidinecarboxylic acid, 5-amino-2-Methyl-, phenylmethyl est
tert-Butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate
(5-AMINO-INDAN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER
4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-benzaldehyde
1-(2-FURYLMETHYL)-2,5-DIMETHYL-1H-PYRROLE-3-CARBALDEHYDE
3-(METHOXYMETHYL)PHENYLBORONIC ACID, PINACOL ESTER
tert-Butyl 6-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate
3-Piperidinecarboxamide,N-(1-methylethyl)-1-(2-pyrimidinyl)-(9CI)
1-(4-AMINOMETHYL-PHENYL)-PIPERIDINE-4-CARBOXYLICACIDETHYLESTER
4-PIPERIDINECARBOXYLICACID, 1-(4-PYRIDINYLMETHYL)-, ETHYL ESTER
tert-butyl 3-(4-aminophenyl)azetidine-1-carboxylate
Etryptamine Acetate
C471 - Enzyme Inhibitor > C667 - Monoamine Oxidase Inhibitor
(S)-(-)-pindolol
l-Pindolol ((-)-pindolol) is a reversible, competitive and orally active 5-HT1A/1B antagonist. l-Pindolol is a partial β-adrenoceptor agonist. l-Pindolol can be used for the research of neurological disease[1][2][3].
2-Hexyloxy-6-hydroxymethyl-tetrahydro-pyran-3,5-diol
Diaminomethylidene-[3-(2-methyl-1-oxopyrrolo[1,2-a]pyrazin-3-yl)propyl]azanium
[(2R)-3-carboxy-2-[(3-hydroxybutanoyl)oxy]propyl]trimethylazanium
[(2S)-3-carboxy-2-[(3R)-3-hydroxybutanoyl]oxypropyl]-trimethylazanium
[3-Carboxy-2-(3-hydroxybutanoyloxy)propyl]-trimethylazanium
3-Methyl-1-(p-tolyl)-2-(trimethylsilyloxy)-2-butene
[3-Hydroxy-2-isopropenyl-3-phenylpropyl]trimethylsilane
Bunitrolol
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
