Exact Mass: 229.0885
Exact Mass Matches: 229.0885
Found 184 metabolites which its exact mass value is equals to given mass value 229.0885,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
benz(a)acridine
CONFIDENCE standard compound; INTERNAL_ID 8030 CONFIDENCE standard compound; INTERNAL_ID 10
Benz[c]acridine
CONFIDENCE standard compound; INTERNAL_ID 8306 CONFIDENCE standard compound; INTERNAL_ID 8119
N-Hydroxy-meIQX
An imidazoquinoxaline that is 3H-imidazo[4,5-f]quinoxaline substituted at positions 3 and 8 by methyl groups and at position 2 by a hydroxyamino group. The active metabolite of the dietary carcinogen MeIQx.
Ergothioneine
Ergothioneine is a naturally occurring metabolite of histidine that has antioxidant properties. -- Pubchem. Ergothioneine is a product of plant origin that accumulates in animal tissues. Ergothioneine is biosynthesized exclusively by fungi and mycobacteria and is captured by plants through their roots. As an ingredient of human food, ET is distributed very unevenly. By far, the highest levels of Ergothioneine have been found in mushrooms (0.1-1 mg/g dried material). Ergothioneine is rapidly cleared from the circulation and then avidly retained with minimal metabolism: the whole-body half-life of ingested Ergothioneine in rats is 1 month. The content of Ergothioneine varies greatly among tissues and is strongly dependent on its dietary level. In addition to erythrocytes and bone marrow, high Ergothioneine levels have also been found in seminal fluid. The precise physiological role of ET has remained elusive since its discovery in 1909. It is known that Ergothioneine is a powerful scavenger of hydroxyl radicals and an inhibitor of iron or copper ion-dependent generation of hydroxyl radicals from hydrogen peroxide (H2O2). A specific ergothioneine transporter has recently been identified (gene symbol SLC22A4 - PMID: 15795384). Ergothioneine appears to play a pivotal protective role in monocytes, because the occurrence of rheumatoid arthritis and Crohns disease has very recently been linked to variant ergothioneine transporter genes (PMID: 15795384). SLC22A4 is highly expressed in the kidney, where it is thought to aid in active secretion of organic cations, and may facilitate the active reabsorption of ergothioneine. A naturally occurring metabolite of histidine that has antioxidant properties. -- Pubchem. Ergothioneine is a product of plant origin that accumulates in animal tissues. Ergothioneine is biosynthesized exclusively by fungi and mycobacteria and is captured by plants through their roots. As an ingredient of human food, ET is distributed very unevenly. By far, the highest levels of Ergothioneine have been found in mushrooms (0.1-1 mg/g dried material). Ergothioneine is rapidly cleared from the circulation and then avidly retained with minimal metabolism: the whole-body half-life of ingested Ergothioneine in rats is 1 month. The content of Ergothioneine varies greatly among tissues and is strongly dependent on its dietary level. In addition to erythrocytes and bone marrow, high Ergothioneine levels have also been found in seminal fluid. The precise physiological role of ET has remained elusive since its discovery in 1909. It is known that Ergothioneine is a powerful scavenger of hydroxyl radicals and an inhibitor of iron or copper ion-dependent generation of hydroxyl radicals from hydrogen peroxide (H2O2). A specific ergothioneine transporter has recently been identified (gene symbol SLC22A4 - PMID: 15795384). Ergothioneine appears to play a pivotal protective role in monocytes, because the occurrence of rheumatoid arthritis and Crohns disease has very recently been linked to variant ergothioneine transporter genes (PMID: 15795384). SLC22A4 is highly expressed in the kidney, where it is thought to aid in active secretion of organic cations, and may facilitate the active reabsorption of ergothioneine. D020011 - Protective Agents > D000975 - Antioxidants Ergothioneine is an imidazole-2-thione derivative with orally active histidine betaine. Ergothioneine is a specific inhibitor of p38-MAPK and Akt, which plays a protective role in cell apoptosis induced by stress. Ergothioneine has antioxidant activity[1][2]. Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant[1].
Endalin
Endalin belongs to the family of Pyrimidine Nucleosides and Analogues. These are compounds comprising a pyrimidine base attached to a sugar. D020011 - Protective Agents > D002316 - Cardiotonic Agents > D002301 - Cardiac Glycosides D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D004791 - Enzyme Inhibitors
Benzo[c]phenanthridine
4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
Lipoxygenase, also known as bw-755c, is a member of the class of compounds known as trifluoromethylbenzenes. Trifluoromethylbenzenes are organofluorine compounds that contain a benzene ring substituted with one or more trifluoromethyl groups. Lipoxygenase is practically insoluble (in water) and a very strong basic compound (based on its pKa). Lipoxygenase can be found in soy bean, which makes lipoxygenase a potential biomarker for the consumption of this food product. Lipoxygenases (EC 1.13.11.-) are a family of (non-heme), iron-containing enzymes most of which catalyze the dioxygenation of polyunsaturated fatty acids in lipids containing a cis,cis-1,4- pentadiene into cell signaling agents that serve diverse roles as autocrine signals that regulate the function of their parent cells, paracrine signals that regulate the function of nearby cells, and endocrine signals that regulate the function of distant cells . D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents BW 755C is a 5-lipoxygenase (5-LO) inhibitor with an IC50 of 5 μM. BW 755C also inhibits cyclooxygenase (COX) with IC50s of 0.65 and 1.2 μg/mL against COX-1 and COX-2, respectively[1][2].
5-(4-Acetamidophenyl)pyrazin-2(1H)-one
D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents
Orgothionenine
Orgothionenine belongs to histidine and derivatives class of compounds. Those are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. Orgothionenine is practically insoluble (in water) and a moderately acidic compound (based on its pKa). Orgothionenine can be found in oat, which makes orgothionenine a potential biomarker for the consumption of this food product.
CAERULOMYCINAMIDE
A pyridine alkaloid that is 2,2-bipyridine substituted by a methoxy group at position 4 and an aminocarbonyl group at position 6. Isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus, it exhibits antineoplastic activity.
2-amino-5-indol-3-ylmethyl-oxazol-4-one|Antibiotic 927A|C-Desmethyl-N-demethyl-indolmycin|N-Demethyl-C-demethyl-indolmycin
(5R)-2-amino-5-(1H-indol-3-ylmethyl)-1,3-oxazol-4-one
Ergothioneine
A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group. A naturally occurring metabolite of histidine synthesized by bacteria and fungi with antioxidant properties. It is found ubiquitously in plants and animals and is present in many human foodstuffs. D020011 - Protective Agents > D000975 - Antioxidants CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 60 Ergothioneine is an imidazole-2-thione derivative with orally active histidine betaine. Ergothioneine is a specific inhibitor of p38-MAPK and Akt, which plays a protective role in cell apoptosis induced by stress. Ergothioneine has antioxidant activity[1][2]. Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant[1].
Endalin
D020011 - Protective Agents > D002316 - Cardiotonic Agents > D002301 - Cardiac Glycosides D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D004791 - Enzyme Inhibitors
dimethyl 3-methyl-4-oxopiperidine-1,3-dicarboxylate
[1-methyl-5-(trifluoromethyl)benzimidazol-2-yl]methanamine
1-(TERT-BUTOXYCARBONYL)-4-OXOPYRROLIDINE-2-CARBOXYLICACID
4-(2-methylpropoxy)pyridine-2-carboximidamide,hydrochloride
4-[(2-methylpropan-2-yl)oxy]pyridine-2-carboximidamide,hydrochloride
(R)-3-Amino-3-phenylpropanoic acid ethyl ester hydrochloride
4-methoxy-7-(3-methyl-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridine
(2-Aminomethyl-benzyl)-phosphonic acid dimethyl ester
(r)-3-amino-4-(2-methylphenyl)butanoic acid hydrochloride
(s)-3-amino-4-(3-methylphenyl)butanoic acid hydrochloride
(r)-3-amino-4-(4-methylphenyl)butanoic acid hydrochloride
6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carboxamide
N-BOC-BELTA-ALANINE-BELTA-METHYL-N-CARBOXYANHYDRIDE
(3-Aminomethyl-benzyl)-phosphonic acid dimethyl ester
tert-butyl-dimethyl-(1,3-thiazol-2-ylmethoxy)silane
N-BOC-BELTA-ALANINE-ALPHA-METHYL-N-CARBOXYANHYDRIDE
(R)-[3,4-(METHYLENEDIOXY)PHENYL]-1-BUTYLAMINE HYDROCHLORIDE
(S)-3-Amino-3-phenylpropanoic acid ethyl ester hydrochloride
6-chloro-1-(2,2-dimethylpropyl)-2H-pyridine-3-carboxylic acid
5-(2-Aminoethyl)-8-hydroxy-4-oxo-1,4-dihydro-3-quinolinecarbonitr ile
(S)-3-amino-3-(o-tolyl)propanoic acid hydrochloride
2-AMINO-1-(4-METHOXY-PHENYL)-5-OXO-4,5-DIHYDRO-1H-PYRROLE-3-CARBONITRILE
Ethanone, 2-chloro-1-[1-(2-methoxyethyl)-2,5-dimethyl-1H-pyrrol-3-yl]- (9CI)
4-ethyl 1-methyl 3-oxopiperidine-1,4-dicarboxylate
ETHYL 2-(4-(AMINOMETHYL)PHENYL)ACETATE HYDROCHLORIDE
2-AMINO-5-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-OL HYDROCHLORIDE
6-[[(2Z)-3-carboxy-1-oxo-2-propenyl]amino]hexanoic acid
tert-Butyl 3,3,3-trifluoro-2-hydroxypropylcarbamate
ALPHA-METHYL-DL-PHENYLALANINE METHYL ESTER HYDROCHLORIDE
(r)-3-amino-4-(3-methylphenyl)butanoic acid hydrochloride
(s)-3-amino-4-(2-methylphenyl)butanoic acid hydrochloride
(s)-3-amino-4-(4-methylphenyl)butanoic acid hydrochloride
N-((2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)METHYL)ETHANAMINE HYDROCHLORIDE
8-(2-CHLORO-ETHYL)-8-AZA-SPIRO[4,5]DECANE-7,9-DIONE
[4-(benzyloxy)tetrahydrofuran-3-yl]amine hydrochloride
3-(4-DIMETHYLAMINOPHENYL)PROPIONIC ACID HYDROCHLORIDE
2-Chloromethyl-4-(3-methoxypropoxy)-3-methylpyridin
6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
2-(4-fluorophenyl)-1-(6-methylpyridin-2-yl)ethanone
(5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione
Ovothiol C
A L-histidine derivative that is N,N-dimethyl-L-histidine substituted at positions N3 and C5 on the imidazole ring by methyl and mercapto groups respectively.
1(2H)-Pyrimidinecarboxamide, N-butyl-5-fluoro-3,4-dihydro-2,4-dioxo-
Anaprox
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D018501 - Antirheumatic Agents > D006074 - Gout Suppressants D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors
L-(+)-ERGOTHIONEINE
(5R)-2-Amino-5-(1H-indol-3-ylmethyl)-1,3-oxazol-4-one
(2S)-2-(dimethylazaniumyl)-3-(1-methyl-4-sulfanyl-1H-imidazol-5-yl)propanoate
N-[(E)-1-Pyridin-3-ylethylideneamino]furan-2-carboxamide
5-[(2S)-2-carboxy-2-(trimethylazaniumyl)ethyl]-1H-imidazole-2-thiolate
2-Hydroxymethyl-1-methyl-5-nitroimidazole, TMS derivative
(Z)-4-methoxy-2,2-bipyridine-6-carbaldehyde oxime
A pyridine alkaloid that is 2,2-bipyridine substituted by a methoxy group at position 4 and a (Z)-(hydroxyimino)methyl group at position 6. It has been isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus.
caerulomycin A
A pyridine alkaloid that is 2,2-bipyridine substituted by a methoxy group at position 4 and a (E)-(hydroxyimino)methyl group at position 6. Isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus, it exhibits antineoplastic activity.
ergothioneine thione form
A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a thioxo group.
ovothiol C zwitterion
An L-alpha-amino acid zwitterion formed from ovothiol C by transfer of a proton from the carboxy to the amino group; major species at pH 7.3.
