Exact Mass: 209.0688046

Hydroxyphenylacetylglycine

[[(4-Hydroxyphenyl)acetyl]amino]acetic acid

Hydroxyphenylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:. acyl-CoA + glycine < -- > CoA + N-acylglycine. Hydroxyphenylacetylglycine is an endogenous human metabolite. It can be originated from the metabolism of tyramine, itself is a monoamine compound derived from the amino acid tyrosine. Hydroxyphenylacetylglycine can also be derived from the metabolism of 3,4-dihydroxyphenylalanine (L-DOPA). In the metabolism of tyrosine, this compound is involved in the reaction Hydroxyphenylacetyl-CoA + Glycine <=> Hydroxyphenylacetylglycine + CoA, catalyzed by acyltransferase enzymes (EC 2.3.1.-). Hydroxyphenylacetylglycine has been identified in human biofluids. (PMID: 14201174, 912020, 716472, 7096501, 7438429, 7438430). Hydroxyphenylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: Hydroxyphenylacetylglycine is an acyl glycine, and an endogenous human metabolite.

3-Carbamoyl-2-phenylpropionic acid

3-(C-hydroxycarbonimidoyloxy)-2-phenylpropanoic acid

3-Carbamoyl-2-phenylpropionic acid is a metabolite of felbamate. Felbamate (marketed under the brand name Felbatol by MedPointe) is an anti-epileptic drug used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drugs usage to severe refractory epilepsy. (Wikipedia)

n-(3-methoxybenzoyl)glycine

(3-IODOPHENOXY)ACETICACIDETHYLESTER

2-(4-Methoxybenzamido)acetic acid

alpha-Methyl-4-carboxyphenylglycine

4-(1-amino-1-carboxyethyl)benzoic acid

D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018691 - Excitatory Amino Acid Antagonists (RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons[1][2].

4-Nitrophenyl butyrate

Para-nitrophenyl butyric acid

4-(4-Chlorophenyl)-3-methyl-3-buten-2-one oxime

N-[4-(4-chlorophenyl)-3-methylbut-3-en-2-ylidene]hydroxylamine

4-[(S)-Amino(carboxy)methyl]-3-methylbenzoic acid

(±)-LY367385 is the racemate of LY367385. LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with > 100 μM for mGlu5a[1][2].

3[N-Morpholino]propane sulfonic acid

3-(morpholin-4-yl)propane-1-sulfonic acid

C7H15NO4S (209.072175)

COVID info from PDB, Protein Data Bank Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

An N,N-dihydroxy-alpha-amino acid having a 5-thiahexyl substituent at the 2-position.

C10H11NO4

NCGC00381049-01_C10H11NO4_

Hydroxyphenylacetylglycine

Hydroxyphenylacetylglycine is an acyl glycine, and an endogenous human metabolite.

N-Benzyloxycarbonylglycine

2-(3-chlorophenyl)-4,4-dimethyl-4,5-dihydrooxazole

2-(2-chlorophenyl)-4,4-dimethyl-4,5-dihydrooxazole

Methylsalicyluric acid

N-(4-cyano-3-methyl-1,2-thiazol-5-yl)butanamide

3-[(4-hydroxybenzoyl)amino]propanoic acid

Ethyl 4-nitrophenylacetate

Ethyl 2-(4-nitrophenyl)acetate

3-CHLORO-1-(2,3-DIHYDRO-1H-INDOL-1-YL)PROPAN-1-ONE

7-Amino-2,3-dihydro-benzo[1,4]dioxine-6-carboxylic acid methyl ester

(R)-(+)-1-PHENYL-1-CYCLOHEXYL-METHANOL

2-methyl-d3-citric acid

C7H7D3O7 (209.061482534)

1,2-BENZENEDIACETIC ACID, 4-AMINO-

1,4,5-TRIAZANAPHTHALENE

(2-Methoxy-benzoylamino)-acetic acid

C10H12ClN3 (209.07197019999998)

3-(6-chloro-1H-benzimidazol-2-yl)propan-1-amine

Dimethyl 4-aminoisophthalate

3-AMINO-2,5,6-TRIMETHYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE

4-ethyl-3-(2-methylfuran-3-yl)-1H-1,2,4-triazole-5-thione

Methyl 4-acetamido-2-hydroxybenzoate

(Z)-11-HEXADECEN-1-YLACETATE

methyl 7-hydroxy-5-oxo-2,3-dihydro-1H-indolizine-8-carboxylate

BIS(3,3,3-TRIFLUOROPROPYL)AMINE

C6H9F6N (209.0639146)

Ethyl 3-methyl-2-nitrobenzoate

1-(3-HYDROXY-4-METHOXYPHENYL)-2-NITROPROPENE

1H-Indole, 1-(chloroacetyl)-2,3-dihydro-7-methyl- (9CI)

1H-Indole, 1-(chloroacetyl)-2,3-dihydro-3-methyl- (9CI)

3-ACETYL-2-AMINO-6-METHOXY-BENZOIC ACID

N-(2-FURFURYLIDENEACETYL)GLYCINE METHYL ESTER

6-(2-METHYL-1,3-DIOXOLAN-2-YL)PICOLINIC ACID

2-ETHYLHEXYLAMINE HYDROBROMIDE

C8H20BrN (209.077902)

3-Methoxy-5-acetylamino-benzoic acid

Phenylalanine,3-carboxy-

3-(2-CARBAMOYLPHENOXY)PROPIONIC ACID

1-(4-CHLOROMETHYL-PHENYL)-PYRROLIDIN-2-ONE

7-methoxycarbonyl-6,7-dihydro-5H-pyrrolizine-1-carboxylic acid

8-chloro-4,4-dimethyl-1,3-dihydroquinolin-2-one

N-(4-THIOUREIDOPHENYL)ACETAMIDE

N,N-Diethyl-2-propyneammonium sulfate

C7H15NO4S (209.072175)

2-(4-Formyl-2-methoxy-phenoxy)-acetamide

Tetraethylammonium bromide

C8H20BrN (209.077902)

D002317 - Cardiovascular Agents > D026902 - Potassium Channel Blockers D049990 - Membrane Transport Modulators

N-Formyl-L-tyrosine

L-Tyrosine, N-formyl-

An N-formyl amino acid that is L-tyrosine in which one of the hydrogens of the amino group has been replaced by a formyl group.

Ethyl 3-methyl-4-nitrobenzoate

3-[(ETHOXYCARBONYL)AMINO]BENZOIC ACID

N-OCTYLAMINE HYDROBROMIDE

C8H20BrN (209.077902)

2,4-DIMETHOXY-OMEGA-NITROSTYRENE

(E)-1,2-DIMETHOXY-3-(2-NITROVINYL)BENZENE

(S)-3-AMINO-3-(2-METHYL-PHENYL)-PROPIONICACID

(R)-3-AMINO-3-(BENZO[D][1,3]DIOXOL-5-YL)PROPANOIC ACID

1-(4-NITROPHENYL)-3-OXO-1-BUTANOL

synkamin hydrochloride

(S)-(-)-1-PHENYLETHYLISOCYANATE

4-(4-Nitrophenyl)butyric acid

2-Nitrophenyl butyrate

1-(3-CHLOROPHENYL)BIGUANIDEHYDROCHLORIDE

C5H12BF3KNO (209.06010679999997)

potassium,2-(dimethylamino)ethoxymethyl-trifluoroboranuide

4-(2-AMINO-2-CARBOXYETHYL)BENZOIC ACID

C9H8FN3O2 (209.06005199999998)

Ethyl 2-fluoro-5H-pyrrolo[2,3-b]pyrazine-6-carboxylate

(S)-4-Ethyl-4-hydroxy-1H-pyrano[3,4-c]pyridine-3,8(4H,7H)-dione

4-Ethyl-3-nitro-benzoic acid Methyl ester

1-(4-CHLORO-PHENYL)-PIPERIDIN-4-ONE

4-Methyl-3-nitrobenzoic acid ethyl ester

(S)-MCPG

D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018691 - Excitatory Amino Acid Antagonists

(4-Chlorophenyl)(pyrrolidin-1-yl)methanone

Benzyl acetoxycarbamate

Methyl 4,5-dimethyl-2-nitrobenzoate

1-AMINO-4,6-DIMETHYL-5-(METHYLTHIO)-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBONITRILE

Methyl 4-acetamido-3-hydroxybenzoate

Benzene,1,2-dimethoxy-3-(2-nitroethenyl)-

1,3-DIMETHOXY-5-(2-NITROVINYL)BENZENE

4-AMINOPHENYLSUCCINIC ACID