Exact Mass: 193.0463
Exact Mass Matches: 193.0463
Found 211 metabolites which its exact mass value is equals to given mass value 193.0463,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
L-Dopachrome
Dopachrome is a cyclization product of L-DOPA and is an intermediate in the biosynthesis of melanin. Dopaquinone has an ortho-quinone ring, which is known to be neurotoxic and highly reactive with many other compounds (PMID: 413870). Dopachrome spontaneously gives rise to 5,6-dihydroxyindole (DHI) or it can be enzymatically metabolized by dopachrome tautomerase to give 5,6-dihydroxyindole-2-carboxylic acid (DHICA). DHI and its oxidation products are also toxic to cells. Many Parkinsons patients are treated with L-DOPA. However, long-term treatment with L-DOPA may actually worsen symptoms or may result in neurotic and psychotic symptoms. These may be due to dopachrome and dopaquinone accumulating in the brain of L-DOPA treated patients (PMID: 19131041, PMID: 12373519). The non-decarboxylative tautomerization of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid in the melanin biosynthetic pathway is catalyzed by Tyrosinase-related protein-2, a melanocyte-specific enzyme. (PMID 11095412) [HMDB]
5,6-Dihydroxyindole-2-carboxylic acid
5,6-Dihydroxyindole-2-carboxylic acid is an intermediate in the metabolism of Tyrosine. It is a substrate for Dopachrome tautomerase. [HMDB] 5,6-Dihydroxyindole-2-carboxylic acid is an intermediate in the metabolism of Tyrosine. It is a substrate for Dopachrome tautomerase.
3-Amino-4,7-dihydroxycoumarin
A hydroxycoumarin that is 4,7-dihydroxycoumarin bearing an additional amino substituent at positions 3.
D-Dopachrome
D-dopachrome is reversibly converted into 5,6-dihydroxyindole and carbon dioxide via the enzyme D-dopachrome decarboxylase (EC 4.1.1.84). Cultured human melanoma cells contain this enzyme as well as human liver (PMID: 8267597). Dopaquinone has an ortho-quinone ring, which is known to be neurotoxic and highly reactive with many other compounds (PMID: 413870). D-dopachrome is reversibly converted to 5,6-dihydroxyindole and carbon dioxide via the enzyme D-dopachrome decarboxylase (EC 4.1.1.84). (KEGG) Cultured human melanoma cells contain this enzyme as well as human liver. (PMID 8267597) [HMDB]
5-Fluoroindole-3-acetic acid
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids
5,6-Dioxo-3,7-dihydro-2H-indole-2-carboxylic acid
Methyl 4-oxo-3-piperidinecarboxylate hydrochloride
3-Oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylic acid
3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-5-CARBOXYLIC ACID
(R)-1-(2,5-Difluorophenyl)ethanamine hydrochloride
5-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
2,2,2-TRIFLUORO-1-(3-FLUOROPHENYL)ETHYLAMINE HYDROCHLORIDE
Methyl 2-oxo-2,3-dihydro-1,3-benzoxazole-6-carboxylate
1-(3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDIN-2-YL)ETHANONE
4-AMINOMETHYL-1-(4-METHOXY-PHENYL)-PYRROLIDIN-2-ONE
Methyl 4-oxopiperidine-3-carboxylate hydrochloride
(3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-YL)BORONIC ACID
4-Amino-1,1-dioxo-tetrahydro-2H-thiopyran-4-carboxylic acid
2-Methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyriMidine-6-carboxylic acid
3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-8-CARBOXYLIC ACID
7-OXO-5,6,7,8-TETRAHYDROPYRIDO[2,3-D]PYRIMIDINE-4-CARBOXYLIC ACID
5-Methyl-4-oxo-1,4-dihydropyrrolo[1,2-f][1,2,4]triazine-6-carboxylic acid
(S)-1-(2,6-Difluorophenyl)ethanamine hydrochloride
3-Amino-4-hydroxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
2-Cyano-4-fluoro-6-methyl-benzoic acid methyl ester
1H-Pyrazole-4-carboxamide, 1-methyl-3-(trifluoromethyl)
Benzene, 1-[(1R)-1-isothiocyanatoethyl]-3-methoxy- (9CI)
Methyl 2-oxo-2,3-dihydro-1,3-benzoxazole-5-carboxylate
3-Oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylicacid
2-Chloro-6-ethyl-5-fluoro-4-hydroxy pyrimidine ammonium salt
ethyl 4-hydroxy-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate
(4R,5S)-(+)-4-METHYL-5-PHENYL-1,3-OXAZOLIDINE-2-THIONE
(S)-1-(2,4-Difluorophenyl)ethanamine hydrochloride
Autoinducer-2
An organic anion that is a borate diester derived from a furanose and acts a universal signal molecule mediating intra- and interspecies communication among bacteria.
gamma-Thiomethyl glutamate
A glutamic acid derivative with a methylsulfanyl group at position 4.
(2R)-2-acetamido-3-[(R)-methylsulfinyl]propanoic acid
5,6-dihydroxyindole-2-carboxylic acid
A dihydroxyindole that is indole-2-carboxylic acid substituted by hydroxy groups at positions 5 and 6.
N-carboxy-L-methionine
A non-proteinogenic L-alpha-amino acid that is L-methionine in which one of the hydrogens attached to the amino group bas been replaced by a carboxy group.
3,4,5,8-quinolinetetrol
A hydroxyquinoline that is quinoline substituted by hydroxy groups at positions 3, 4, 5, and 8.
