Exact Mass: 186.1157
Exact Mass Matches: 186.1157
Found 88 metabolites which its exact mass value is equals to given mass value 186.1157,
within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error
0.0002 dalton.
Detomidine
A profound lethargy and characteristic lowering of the head with reduced sensitivity to environmental stimuli (sound, pain, etc.) are seen with detomidine. A short period of reduced coordination is characteristically followed by immobility and a firm stance with front legs spread. Following administration there is an initial increase in blood pressure, followed by bradycardia and second degree atrioventricular block (this is not pathologic in horses). The horse commonly sweats to excess, especially on the flanks and neck. Other side effects reported include pilo erection (hair standing erect), ataxia, salivation, slight muscle tremors, and (rarely) penile prolapse. An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine. [PubChem]; As detomidine is an arrhythmogenic agent, extreme care should be exercised in horses with cardiac disease, and in the concurrent administration of other arrhythmogenics. The concurrent use of potentiated sulfonamide antibiotics is considered particularly dangerous. Detomidine is a poor premedication when using Ketamine as an anesthetic in horses. Detomidine is a sedative with analgesic properties. 2-adrenergic agonists produce dose-dependent sedative and analgesic effects, mediatated by activation of catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action. Detomidine is an imidazole derivative and I-adrenergic agonist, used as a large animal sedative, primarily used in horses. It is usually available as the salt detomidine hydrochloride. It is a prescription medication available to veterinarians sold under the trade name Dormosedan. D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
PARAQUAT
D010575 - Pesticides > D006540 - Herbicides COVID info from COVID-19 Disease Map D016573 - Agrochemicals Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
1,2,3,4-Tetrahydro-2-methyl-b-carboline
1,2,3,4-Tetrahydro-2-methyl-b-carboline is found in fruits. 1,2,3,4-Tetrahydro-2-methyl-b-carboline is an alkaloid from Elaeagnus angustifolia (Russian olive
1-Phenyl-5-propyl-1H-pyrazole
1-Phenyl-5-propyl-1H-pyrazole is a flavouring ingredient. Flavouring ingredient
Pyrido[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-6-methyl- (9CI)
Quinoxaline, 1,2-dihydro-3-methyl-2-(2-propenyl)- (9CI)
Pyrido[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-3-methyl- (9CI)
1,2,3,9-TETRAHYDRO-2-METHYL-PYRROLO[2,1-B]QUINAZOLINE
2,3,4,5-TETRAHYDRO-8-METHYL-1H-PYRIDO[4,3-B]INDOLE
Pyrido[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-1-methyl- (7CI)
(4-METHYL-6,7-DIHYDRO-4H-THIENO[3,2-C]PYRAN-4-YL)ACETICACID
1H-Benzimidazole,1-methyl-2-(2-methylcyclopropyl)-(9CI)
Propanedinitrile,2-(3,5,5-trimethyl-2-cyclohexen-1-ylidene)-
6-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
1H-Benzimidazole,1-(1,2-dimethyl-2-propenyl)-(9CI)
1H-Benzimidazole,2-methyl-1-(2-methyl-2-propenyl)-(9CI)
1H-Benzimidazole,5,6-dimethyl-1-(2-propenyl)-(9CI)
Pyrido[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-7-methyl- (7CI,8CI,9CI)
1H-Pyrido[4,3-b]indole,2,3,4,5-tetrahydro-2-methyl-
2-(Dimethylamino)-2,3-dihydro-1H-indene-2-carbonitrile
DETOMIDINE
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
